木村 信也
薬理学 | 講師 |
Last Updated :2024/12/13
研究者情報
研究活動情報
論文
- Repeated Social Defeat Stress Induces HMGB1 Nuclear Export in Prefrontal Neurons, Leading to Social Avoidance in Mice.
Shiho Kitaoka; Ayaka Tomohiro; Shinya Ukeshima; Keyue Liu; Hidenori Wake; Shinya H Kimura; Yasuhiko Yamamoto; Masahiro Nishibori; Tomoyuki Furuyashiki
Cells, 2023年07月 - Prostaglandin E2 increases the expression of cyclooxygenase-2 in cultured rat microglia.
Takayuki Nagano; Naohiko Tsuda; Kenichi Fujimura; Yuji Ikezawa; Yuki Higashi; Shinya H. Kimura
Journal of Neuroimmunology, 2021年12月, [査読有り]
ラスト(シニア)オーサー - Prostaglandin E<sub>2</sub> increases expression of mRNA for cyclooxygenase-2 and microsomal prostaglandin E synthase-1 in microglia.
Takayuki Nagano; Naohiko Tsuda; Kenichi Fujimura; Yuji Ikezawa; Yuki Higashi; Shinya H. Kimura; Motohiko Takemura
Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2020年 - Prostaglandin E2 potentiates interferon-γ-induced nitric oxide production in cultured rat microglia.
Nagano T; Nishiyama R; Sanada A; Mutaguchi Y; Ioku A; Umeki H; Kishimoto S; Yamanaka D; Kimura SH; Takemura M
Journal of neurochemistry, 2017年02月, [査読有り] - Prostaglandin E-2 induces apoptosis in cultured rat microglia
Takayuki Nagano; Shinya H. Kimura; Motohiko Takemura
BRAIN RESEARCH, 2014年06月, [査読有り] - Prostaglandin E-2 reduces amyloid beta-induced phagocytosis in cultured rat microglia
Takayuki Nagano; Shinya H. Kimura; Motohiko Takemura
BRAIN RESEARCH, 2010年04月, [査読有り] - Prostaglandin E(2) reduces extracellular ATP-induced migration in cultured rat microglia
Takayuki Nagano; Shinya H. Kimura; Motohiko Takemura
BRAIN RESEARCH, 2008年07月, [査読有り] - RECS1 deficiency in mice induces susceptibility to cystic medial degeneration
Hanjun Zhao; Akihiko Ito; Shinya H. Kimura; Norikazu Yabuta; Naohiko Sakai; Masahito Ikawa; Masaru Okabe; Yuji Matsuzawa; Shizuya Yamashita; Hiroshi Nojima
GENES & GENETIC SYSTEMS, 2006年02月, [査読有り] - Lipopolysaccharide sensitizes microglia toward Ca2+-induced cell death: Mode of cell death shifts from apoptosis to necrosis
T Nagano; SH Kimura; E Takai; T Matsuda; M Takemura
GLIA, 2006年01月, [査読有り] - A truncated isoform of the PP2A B56γ regulatory subunit reduces irradiation-induced Mdm2 phosphorylation and could contribute to metastatic melanoma cell radioresistance
Y. I. Koma; Akihiko Ito; K. Watabe; S. H. Kimura; Y. Kitamura
Histology and Histopathology, 2004年04月, [査読有り] - Cyclin G1 associates with MDM2 and regulates accumulation and degradation of p53 protein
SH Kimura; H Nojima
GENES TO CELLS, 2002年08月, [査読有り]
筆頭著者 - Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery
Shinya H. Kimura; Masahito Ikawa; Akihiko Ito; Masaru Okabe; Hiroshi Nojima
Oncogene, 2001年, [査読有り]
筆頭著者 - Expression of a mammalian DNA photolyase confers light-dependent repair activity and reduces mutations of UV-irradiated shuttle vectors in xeroderma pigmentosum cells
H Asahina; ZB Han; M Kawanishi; T Kato; H Ayaki; T Todo; T Yagi; H Takebe; M Ikenaga; SH Kimura
MUTATION RESEARCH-DNA REPAIR, 1999年12月, [査読有り]
ラスト(シニア)オーサー - Genomic structure and chromosomal localization of mouse cyclin G1 gene
SH Kimura; TR Kataoka; Y Endo; H Nojima
GENOMICS, 1997年12月, [査読有り]
筆頭著者 - Structure, expression, and chromosomal localization of human GAK
SH Kimura; H Tsuruga; N Yabuta; Y Endo; H Nojima
GENOMICS, 1997年09月, [査読有り]
筆頭著者 - GAK: A cyclin G associated kinase contains a tensin/auxilin-like domain
Yoshihide Kanaoka; Shinya H. Kimura; Issey Okazaki; Masako Ikeda; Hiroshi Nojima
FEBS Letters, 1997年02月, [査読有り]
筆頭著者
MISC
- ミクログリアの誘導型一酸化窒素合成酵素発現に対するPGE2受容体アゴニストとアンタゴニストの影響
西山遼; 長野貴之; 眞田彩加; 牟田口由紀子; 井奥杏奈; 楳木博久; 岸本聖; 山中大輔; 木村信也; 竹村基彦
日本薬理学会近畿部会プログラム・要旨集, 2016年 - Prostaglandin E-2 induces apoptosis in cultured rat microglia
Takayuki Nagano; Shinya H. KImura; Motohiko Takemura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013年 - Microglial activation is reduced by prostaglandin E2
Takayuki Nagano; Shinya H. Kimura; Motohiko Takemura
Microglia: Biology, Functions and Roles in Disease, 2012年12月01日 - Prostaglandin E-2 reduces amyloid beta(1-42)-induced phagocytosis in microglia
Takayuki Nagano; Shinya H. Kimura; Motohiko Takemura
NEUROSCIENCE RESEARCH, 2010年 - Prostaglandin E-2 inhibits amyloid beta(25-35)-induced phagocytosis in cultured rat microglia
Takayuki Nagano; Shinya H. Kimura; Motohiko Takemura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009年 - Prostaglandin E-2 inhibits extracellular ATP-induced migration in cultured rat microglia
Takayuki Nagano; Shinya H. Kimura; Motohiko Takemura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2008年 - Lipopolysaccharide decreases intracellular ATP level via p38 mitogen-activated protein kinase and poly(ADP-ribose) polymerase in cultured rat microglia.
Takayuki Nagano; Shinya H. Kimura; Eri Takai; Motohiko Takemura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2007年 - Barbiturates inhibit apoptosis induced by reactive oxygen species in PC12
Shinya Kimura; Jiping Ren; Takayuki Nagano; Motohiko Takemura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2007年 - RECS1, a novel shear stress-upregulated gene in endothelial cells, suppresses Fas-mediated apoptosis
SH Kimura; T Tsujimura; H Yoshisue; H Nojima; M Takemura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004年 - Cyclin G1 associates with MDM2 and regulates accumulation and degradation of p53 protein :
Kimura Shinya H.; Takemura Motohiko; Nojima Hiroshi
Journal of radiation research, 2002年 - shear stress応答性cDNAの包括的単離と動脈硬化における役割の解明
大屋健; 山下静也; 酒井尚彦; ちょう漢軍; 吉末元; 木村信也; 野島博; 松沢佑次
動脈硬化, 2001年05月15日 - shear stress 応答性cDNAの包括的単離と動脈硬化における役割の解明
大屋 健; 山下 静也; 酒井 尚彦; 趙 漢軍; 吉末 元; 木村 信也; 野島 博; 松澤 佑次
動脈硬化 = The journal of Japan Atherosclerosis Society, 2001年05月15日 - Cyclin G1はDNA損傷後のG2/M期停止と,損傷回復後の増殖制御に関与している
木村信也; 伊川正人; 伊藤彰彦; 岡部勝; 野島博
日本分子生物学会年会プログラム・講演要旨集, 2000年11月25日