江嵜 啓祥
| 化学 | 准教授 |
| 医学教育センター |
Last Updated :2024/08/30
研究者情報
経歴
研究活動情報
論文
- Synthesis of 4-Imidazolidinones from Diamides and Ethynyl Benziodoxolones via Double Michael-Type Addition: Ethynyl Benziodoxolones as Electrophilic Ynol Synthons
Ayaka Shimizu; Atsushi Shibata; Takashi Kano; Yuuichi Kumai; Ryouhei Kawakami; Hiroyoshi Esaki; Kazuaki Fukushima; Norihiro Tada; Akichika Itoh
Organic Letters, 2022年11月, ［査読有り］
責任著者 - Theoretical Study of the Mechanism of Ribosomal Peptide Bond Formation Using the ONIOM Method
Kazuaki Fukushima; Hiroyoshi Esaki
Chemical and Pharmaceutical Bulletin, 2021年08月, ［査読有り］ - Enantioselective Protonation of Cyclic Carbonyl Ylides by Chiral Lewis Acid Assisted Alcohols
Yasunori Toda; Takayuki Yoshida; Kaoru Arisue; Kazuaki Fukushima; Hiroyoshi Esaki; Ayaka Kikuchi; Hiroyuki Suga
Chemistry – A European Journal, 2021年07月, ［査読有り］ - Methoxy Groups Increase Reactivity of Bifunctional Tetraarylphosphonium Salt Catalysts for Carbon Dioxide Fixation: A Mechanistic Study
Yasunori Toda; Yutaka Komiyama; Hiroyoshi Esaki; Kazuaki Fukushima; Hiroyuki Suga
The Journal of Organic Chemistry, 2019年12月, ［査読有り］ - Enantioselective Cycloadditions between Aliphatic Nitrile Oxides And 2-Hydroxystyrenes Catalyzed by Chiral Amine-urea
Yasunori Toda; Masato Koyama; Hiroyoshi Esaki; Kazuaki Fukushima; Hiroyuki Suga
Heterocycles, 2018年, ［査読有り］ - Amine-Urea-Mediated Asymmetric Cycloadditions between Nitrile Oxides and o-Hydroxystyrenes by Dual Activation
Hiroyuki Suga; Yohei Hashimoto; Yasunori Toda; Kazuaki Fukushima; Hiroyoshi Esaki; Ayaka Kikuchi
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017年09月, ［査読有り］ - Highly chemoselective hydrogenation method using Pd on spherical carbon
Esaki Hiroyoshi; Hattori Tomohiro; Tsubone Aya; Mibayashi Satoko; Sakata Takao; Sawama Yoshinari; Monguchi Yasunari; Yasuda Hidehiro; Nosaka Kazuto; Sajiki Hironao
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014年08月, ［査読有り］ - Enzymatic and structural characterization of an archaeal thiamin phosphate synthase
Maria Hayashi; Kazuya Kobayashi; Hiroyoshi Esaki; Hiroyuki Konno; Kenichi Akaji; Keiko Tazuya; Kazuko Yamada; Toshikatsu Nakabayashi; Kazuto Nosaka
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2014年04月, ［査読有り］ - SYNTHESIS OF 4-ARYLPIPERIDIN-4-OL DERIVATIVES OF LOPERAMIDE AS AGENTS WITH POTENT ANTIPROLIFERATIVE EFFECTS AGAINST HCT-116 AND HL-60 CELLS
Noriyuki Hatae; Tomoyuki Nagayama; Hiroyoshi Esaki; Eiko Kujime; Masabumi Minami; Minoru Ishikura; Tominari Choshi; Satoshi Hibino; Chiaki Okada; Eiko Toyota; Hideko Nagasawa; Tatsunori Iwamura
HETEROCYCLES, 2014年01月, ［査読有り］ - Chemoselective Hydrogenation Catalyzed by Pd on Spherical Carbon
Hiroyoshi Esaki; Tomohiro Hattori; Aya Tsubone; Satoko Mibayashi; Takao Sakata; Yoshinari Sawama; Yasunari Monguchi; Hidehiro Yasuda; Kazuto Nosaka; Hironao Sajiki
CHEMCATCHEM, 2013年12月, ［査読有り］ - トランスケトラーゼ様タンパク質はトランスケトラーゼ活性を持たない
野坂和人; 江嵜啓祥
ビタミン, 2013年, ［査読有り］ - Facilitated recruitment of Pdc2p, a yeast transcriptional activator, in response to thiamin starvation
Kazuto Nosaka; Hiroyoshi Esaki; Mari Onozuka; Hiroyuki Konno; Yasunao Hattori; Kenichi Akaji
FEMS MICROBIOLOGY LETTERS, 2012年05月, ［査読有り］ - Efficient and Selective Pt/C-Catalyzed H–D Exchange Reaction of Aromatic Rings
Nobuhiro Ito; Hiroyoshi Esaki; Tsuneaki Maesawa; Eikoh Imamiya; Tomohiro Maegawa; Hironao Sajiki
Bulletin of the Chemical Society of Japan, 2008年02月, ［査読有り］ - Mild and Efficient H–D Exchange of Alkanes Based on C–H Activation Catalyzed by Heterogeneous Rhodium on Charcoal
Tomohiro Maegawa; Yuta Fujiwara; Yuya Inagaki; Hiroyoshi Esaki; Yasunari Monguchi; Hironao Sajiki
Angewandte Chemie International Edition, 2008年, ［査読有り］ - Facile and Convenient Method of Deuterium Gas Generation Using a Pd/C-Catalyzed H2–D2 Exchange Reaction and Its Application to Synthesis of Deuterium-Labeled Compounds
Takanori Kurita; Fumiyo Aoki; Takuto Mizumoto; Toshihide Maejima; Hiroyoshi Esaki; Tomohiro Maegawa; Yasunari Monguchi; Hironao Sajiki
Chemistry-A European Journal, 2008年, ［査読有り］ - Novel Pd/C-Catalyzed Redox Reactions between Aliphatic Secondary Alcohols and Ketones under Hydrogenation Conditions: Application to H–D Exchange Reaction and the Mechanistic Study
Hiroyoshi Esaki; Rumi Ohtaki; Tomohiro Maegawa; Yasunari Monguchi; Hironao Sajiki
Journal of Organic Chemistry, 2007年03月, ［査読有り］ - 不均一系白金族触媒を用いた重水素標識化反応
江嵜啓祥; 栗田貴教; 藤原佑太; 前川智弘; 門口泰也; 佐治木弘尚
有機合成化学協会誌, 2007年, ［査読有り］ - Efficient H/D Exchange Reactions of Alkyl-Substituted Benzene Derivatives by Means of the Pd/C–H2–D2O System
Hiroyoshi Esaki; Fumiyo Aoki; Miho Umemura; Masatsugu Kato; Tomohiro Maegawa; Yasunari Monguchi; Hironao Sajiki
Chemistry-A European Journal, 2007年, ［査読有り］ - General method of obtaining deuterium-labeled heterocyclic compounds using neutral D2O with heterogeneous Pd/C
Hiroyoshi Esaki; Nobuhiro Ito; Shino Sakai; Tomohiro Maegawa; Yasunari Monguchi; Hironao Sajiki
TETRAHEDRON, 2006年11月, ［査読有り］ - Synthesis of Base-Selectively Deuterium-Labelled Nucleosides by the Pd/C-Catalyzed H–D Exchange Reaction in Deuterium Oxide
Hiroyoshi Esaki; Fumiyo Aoki; Tomohiro Maegawa; Kosaku Hirota; Hironao Sajiki
Heterocycles, 2005年12月, ［査読有り］ - Aromatic Ring Favorable and Efficient H–D Exchange Reaction Catalyzed by Pt/C
Hironao Sajiki; Nobuhiro Ito; Hiroyoshi Esaki; Tsuneaki Maesawa; Tomohiro Maegawa; Kosaku Hirota
Tetrahedron Letters, 2005年10月, ［査読有り］ - Palladium-Catalyzed Base-Selective H–D Exchange Reaction of Nucleosides in Deuterium Oxide
Hironao Sajiki; Hiroyoshi Esaki; Fumiyo Aoki; Tomohiro Maegawa; Kosaku Hirota
Synlett, 2005年06月, ［査読有り］ - Efficient and selective deuteration of phenylalanine derivatives catalyzed by Pd/C
T Maegawa; A Akashi; H Esaki; F Aoki; H Sajiki; K Hirota
SYNLETT, 2005年03月, ［査読有り］ - Complete replacement of H-2 by D-2 via Pd/C-catalyzed H/D exchange reaction
H Sajiki; T Kurita; H Esaki; F Aoki; T Maegawa; K Hirota
ORGANIC LETTERS, 2004年09月, ［査読有り］ - Efficient C–H/C–D Exchange Reaction on the Alkyl Side Chain of Aromatic Compounds Using Heterogeneous Pd/C in D2O
Hironao Sajiki; Fumiyo Aoki; Hiroyoshi Esaki; Tomohiro Maegawa; Kosaku Hirota
Organic Letters, 2004年04月, ［査読有り］
MISC
- Multiple/regioselective H-D exchange reaction of aliphatic alkanes and alcohols
Yuta Fujiwara; Hiroyoshi Esaki; Tomohiro Maegawa; Yasunari Monguchi; Hironao Sajiki
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009年08月
書籍等出版物
共同研究・競争的資金等の研究課題
- 中分子創薬に資するトリアゾール人工生命鎖の開発
2023年度 武田科学振興財団 薬学系研究助成
岐阜薬科大学
2028年03月 - 計算化学的スクリーニングを利用した有機分子触媒反応の設計および開発
基盤研究(C)
信州大学
2017年07月 - 2020年03月 - 新規パラジウム触媒Pd@iO-braneTMを利用した鈴木－宮浦反応の開発
2014年 - 2015年 - 新規パラジウム触媒の機能性開発研究
2012年 - 2014年 - ロペラミドをリード化合物とした新規抗腫瘍薬の開発研究
2010年 - 2011年 - パラジウム触媒を用いた新規重水素標識化法に関する研究
2005年 - 2006年 - Efficient deuterium labeling method of biologically active compounds
2004年
