Last Updated :2024/09/11
Researcher Information
Career
- Oct. 2020 - Present
Hyogo Medical University, Division of Biology, Associate Professor - Jul. 2013 - Mar. 2024
CDB, RIKEN, Visiting Scientist - Jul. 2013 - Sep. 2020
Hyogo College of Medicine, Division of Biology, Associate Professor - Jun. 2013 - Jun. 2013
Hyogo College of Medicine, Division of Biology, Part time lecturer - Apr. 2011 - Jun. 2013
RIKEN CDB, Research Scientist - Apr. 2008 - Mar. 2011
RIKEN CDB, Junior Research Associate - Apr. 2001 - Mar. 2008
High School, Teacher of Science
Research activity information
Award
- Jan. 2024
兵庫医科大学, 教員活動奨励賞
菅原文昭 - Dec. 2022
兵庫医科大学, 教員活動奨励賞
菅原文昭 - Oct. 2021
兵庫医科大学, 教員活動奨励賞
菅原 文昭 - Jan. 2020
兵庫医科大学, 教員活動奨励賞
菅原 文昭 - Mar. 2017
Hyogo College of Medicine, Best teacher award
Fumiaki Sugahara - Sep. 2016
Hyogo College of Medicine, Research Award
Fumiaki Sugahara - Mar. 2016
Hyogo College of Medicine, President's Special Award
Fumiaki Sugahara
Paper
- Hagfish genome elucidates vertebrate whole-genome duplication events and their evolutionary consequences.
Daqi Yu; Yandong Ren; Masahiro Uesaka; Alan J S Beavan; Matthieu Muffato; Jieyu Shen; Yongxin Li; Iori Sato; Wenting Wan; James W Clark; Joseph N Keating; Emily M Carlisle; Richard P Dearden; Sam Giles; Emma Randle; Robert S Sansom; Roberto Feuda; James F Fleming; Fumiaki Sugahara; Carla Cummins; Mateus Patricio; Wasiu Akanni; Salvatore D'Aniello; Cristiano Bertolucci; Naoki Irie; Cantas Alev; Guojun Sheng; Alex de Mendoza; Ignacio Maeso; Manuel Irimia; Bastian Fromm; Kevin J Peterson; Sabyasachi Das; Masayuki Hirano; Jonathan P Rast; Max D Cooper; Jordi Paps; Davide Pisani; Shigeru Kuratani; Fergal J Martin; Wen Wang; Philip C J Donoghue; Yong E Zhang; Juan Pascual-Anaya
Nature ecology & evolution, Jan. 2024, [Reviewed] - Comparative analysis of Hmx expression and the distribution of neuronal somata in the trigeminal ganglion in lamprey and shark: insights into the homology of the trigeminal nerve branches and the evolutionary origin of the vertebrate jaw
Motoki Tamura; Ryota Ishikawa; Yuki Nakanishi; Juan Pascual-Anaya; Makiko Fukui; Takashi Saitou; Fumiaki Sugahara; Filippo M. Rijli; Shigeru Kuratani; Daichi G. Suzuki; Yasunori Murakami
Zoological Letters, Dec. 2023, [Reviewed] - Ultrastructure of the lamprey head mesoderm reveals evolution of the vertebrate head
Takayuki Onai; Noritaka Adachi; Hidetoshi Urakubo; Fumiaki Sugahara; Toshihiro Aramaki; Mami Matsumoto; Nobuhiko Ohno
iScience, Nov. 2023, [Reviewed] - High-quality total RNA extraction from early-stage lamprey embryos
Fumiaki Sugahara; Juan Pascual-Anaya
BioTechniques, May 2023, [Reviewed]
Lead - Evolutionary origin of vertebrate OCT4/POU5 functions in supporting pluripotency.
Woranop Sukparangsi; Elena Morganti; Molly Lowndes; Hélène Mayeur; Melanie Weisser; Fella Hammachi; Hanna Peradziryi; Fabian Roske; Jurriaan Hölzenspies; Alessandra Livigni; Benoit Gilbert Godard; Fumiaki Sugahara; Shigeru Kuratani; Guillermo Montoya; Stephen R Frankenberg; Sylvie Mazan; Joshua M Brickman
Nature communications, Sep. 2022 - Thyroid and endostyle development in cyclostomes provides new insights into the evolutionary history of vertebrates.
Wataru Takagi; Fumiaki Sugahara; Shinnosuke Higuchi; Rie Kusakabe; Juan Pascual-Anaya; Iori Sato; Yasuhiro Oisi; Nobuhiro Ogawa; Hiroshi Miyanishi; Noritaka Adachi; Susumu Hyodo; Shigeru Kuratani
BMC biology, Apr. 2022 - Comparative developmental studies reveal the origin and evolution of the vertebrate cerebellum
Fumiaki Sugahara; Yasunori Murakami
Acta Med. Hyogo., Mar. 2022 - Forebrain Architecture and Development in Cyclostomes, with Reference to the Early Morphology and Evolution of the Vertebrate Head.
Fumiaki Sugahara; Yasunori Murakami; Juan Pascual-Anaya; Shigeru Kuratani
Brain, behavior and evolution, Sep. 2021, [Reviewed]
Lead - Genetic Mechanism for the Cyclostome Cerebellar Neurons Reveals Early Evolution of the Vertebrate Cerebellum.
Fumiaki Sugahara; Juan Pascual-Anaya; Shigehiro Kuraku; Shigeru Kuratani; Yasunori Murakami
Frontiers in cell and developmental biology, 2021, [Reviewed]
Lead - FGF- and SHH-based molecular signals regulate barbel and craniofacial development in catfish.
Itoyama T; Fukui M; Kawaguchi M; Kaneko S; Sugahara F; Murakami Y
Zoological letters, Jun. 2019, [Reviewed] - Evolution of the Vertebrate Semicircular Canals Revealed by the Inner Ear Development in Hagfishes and Lampreys
Fumiaki Sugahara; Shinnosuke Higuchi
Acta Med. Hyogo, Mar. 2019, [Invited] - Inner ear development in cyclostomes and evolution of the vertebrate semicircular canals.
Higuchi S; Sugahara F; Pascual-Anaya J; Takagi W; Oisi Y; Kuratani S
Nature, Jan. 2019, [Reviewed] - Hagfish and lamprey Hox genes reveal conservation of temporal colinearity in vertebrates
Juan Pascual-Anaya; Iori Sato; Fumiaki Sugahara; Shinnosuke Higuchi; Jordi Paps; Yandong Ren; Wataru Takagi; Adrián Ruiz-Villalba; Kinya G. Ota; Wen Wang; Shigeru Kuratani
Nature Ecology and Evolution, May 2018, [Reviewed] - Expansions, diversification, and interindividual copy number variations of AID/APOBEC family cytidine deaminase genes in lampreys
Stephen J. Holland; Lesley M. Berghuis; Justin J. King; Lakshminarayan M. Iyer; Katarzyna Sikora; Heather Fifield; Sarah Peter; Emma M. Quinlan; Fumiaki Sugahara; Prashant Shingate; Inês Trancoso; Norimasa Iwanami; Elena Temereva; Christine Strohmeier; Shigeru Kuratani; Byrappa Venkatesh; Guillaume Evanno; L. Aravind; Michael Schorpp; Mani Larijani; Thomas Boehm
Proceedings of the National Academy of Sciences of the United States of America, Apr. 2018, [Reviewed] - Evidence from Cyclostomes for Ancestral Developmental Plan and Evolution of the Vertebrate Brain
Fumiaki Sugahara
Acta Med. Hyogo., Sep. 2017, [Invited] - Reconstructing the ancestral vertebrate brain
Fumiaki Sugahara; Yasunori Murakami; Juan Pascual-Anaya; Shigeru Kuratani
DEVELOPMENT GROWTH & DIFFERENTIATION, May 2017, [Reviewed] - Developmental origin of the clavicle, and its implications for the evolution of the neck and the paired appendages in vertebrates
Hiroshi Nagashima; Fumiaki Sugahara; Keisuke Watanabe; Masahiro Shibata; Akina Chiba; Noboru Sato
JOURNAL OF ANATOMY, Oct. 2016, [Reviewed] - On the Vagal Cardiac Nerves, with Special Reference to the Early Evolution of the Head-Trunk Interface
Hiroki Higashiyama; Tatsuya Hirasawa; Yasuhiro Oisi; Fumiaki Sugahara; Susumu Hyodo; Yoshiakira Kanai; Shigeru Kuratani
JOURNAL OF MORPHOLOGY, Sep. 2016, [Reviewed] - Evidence from cyclostomes for complex regionalization of the ancestral vertebrate brain.
Fumiaki Sugahara; Juan Pascual-Anaya; Yasuhiro Oisi; Shigehiro Kuraku; Shin-ichi Aota; Noritaka Adachi; Wataru Takagi; Tamami Hirai; Noboru Sato; Yasunori Murakami; Shigeru Kuratani
Nature, Mar. 2016, [Reviewed] - Reevaluating Emx gene phylogeny: homopolymeric amino acid tracts as a potential factor obscuring orthology signals in cyclostome genes.
Miyuki Noro; Fumiaki Sugahara; Shigehiro Kuraku
BMC evolutionary biology, May 2015, [Reviewed] - On the Homology of the Shoulder Girdle in Turtles
Hiroshi Nagashima; Fumiaki Sugahara; Masaki Takechi; Noboru Sato; Shigeru Kuratani
JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION, May 2015, [Reviewed] - Gene expression analysis of lamprey embryos
Fumiaki Sugahara; Yasunori Murakami; Shigeru Kuratani
In Situ Hybridization Methods, Feb. 2015, [Reviewed] - Origin of the unique morphology of the shoulder girdle in turtles
Hiroshi Nagashima; Tatsuya Hirasawa; Fumiaki Sugahara; Masaki Takechi; Ryo Usuda; Noboru Sato; Shigeru Kuratani
JOURNAL OF ANATOMY, Dec. 2013, [Reviewed] - Evolution of the regionalization and patterning of the vertebrate telencephalon: What can we learn from cyclostomes?
Fumiaki Sugahara; Yasunori Murakami; Noritaka Adachi; Shigeru Kuratani
Current Opinion in Genetics and Development, Aug. 2013, [Reviewed] - Body wall development in lamprey and a new perspective on the origin of vertebrate paired fins
Frank J. Tulenko; David W. McCauley; Ethan L. MacKenzie; Sylvie Mazan; Shigeru Kuratani; Fumiaki Sugahara; Rie Kusakabe; Ann C. Burke
Proceedings of the National Academy of Sciences of the United States of America, Jul. 2013, [Reviewed] - Developmental and evolutionary significance of the mandibular arch and prechordal/premandibular cranium in vertebrates: revising the heterotopy scenario of gnathostome jaw evolution
Shigeru Kuratani; Noritaka Adachi; Naoyuki Wada; Yasuhiro Oisi; Fumiaki Sugahara
JOURNAL OF ANATOMY, Jan. 2013, [Reviewed] - Involvement of Hedgehog and FGF signalling in the lamprey telencephalon: evolution of regionalization and dorsoventral patterning of the vertebrate forebrain.
Fumiaki Sugahara; Shin-ichi Aota; Shigehiro Kuraku; Yasunori Murakami; Yoko Takio-Ogawa; Shigeki Hirano; Shigeru Kuratani
Development (Cambridge, England), Mar. 2011, [Reviewed] - Evolution of oropharyngeal patterning mechanisms involving Dlx and endothelins in vertebrates.
Shigehiro Kuraku; Yoko Takio; Fumiaki Sugahara; Masaki Takechi; Shigeru Kuratani
Developmental biology, May 2010, [Reviewed] - Evolution of the Turtle Body Plan by the Folding and Creation of New Muscle Connections
Hiroshi Nagashima; Fumiaki Sugahara; Masaki Takechi; Rolf Ericsson; Yoshie Kawashima-Ohya; Yuichi Narita; Shigeru Kuratani
SCIENCE, Jul. 2009, [Reviewed] - A new evolutionary scenario for the vertebrate jaw
Y Shigetani; F Sugahara; S Kuratani
BIOESSAYS, Mar. 2005, [Reviewed] - Heterotopic shift of epithelial-mesenchymal interactions in vertebrate jaw evolution
Y Shigetani; F Sugahara; Y Kawakami; Y Murakami; S Hirano; S Kuratani
SCIENCE, May 2002, [Reviewed] - Compartments in the lamprey embryonic brain as revealed by regulatory gene expression and the distribution of reticulospinal neurons
Y Murakami; M Ogasawara; P Satoh; F Sugahara; M Myojin; S Hirano; S Kuratani
BRAIN RESEARCH BULLETIN, Feb. 2002, [Reviewed] - Identification and expression of the lamprey Pax6 gene: evolutionary origin of the segmented brain of vertebrates
Y Murakami; M Ogasawara; F Sugahara; S Hirano; N Satoh; S Kuratani
DEVELOPMENT, Sep. 2001 - Isolation of Dlx and Emx gene cognates in an agnathan species, Lampetra japonica, and their expression patterns during embryonic and larval development: Conserved and diversified regulatory patterns of homeobox genes in vertebrate head evolution
M Myojin; T Ueki; F Sugahara; Y Murakami; Y Shigetani; S Aizawa; S Hirano; S Kuratani
JOURNAL OF EXPERIMENTAL ZOOLOGY, Apr. 2001, [Reviewed]
MISC
Books and other publications
- 生物の科学 遺伝 2024年7月号
上坂将弘; 菅原文昭; 倉谷滋; フアン・パスクァル・アナヤ, Joint work, 円口類ヌタウナギと脊椎動物初期進化における全ゲノム重複
Jun. 2024
9784860438678 - Origin and evolution of animals approached by experimental biology
Fumiaki Sugahara; Yasunori Murakami, Contributor, Developmental origin and evolution of the cerebellum: Insights from cyclostomes
New Science Co., Ltd. Tokyo, Japan, Apr. 2024 - 【Clinical Neuroscience 2023年12月号】脳の進化―多様性と可能性
菅原文昭, Contributor, 無顎類の神経系―ヌタウナギ，ヤツメウナギの神経系の特徴と進化の過程
中外医学社, Dec. 2023 - Handbook of Marine Model Organisms in Experimental Biology: Established and Emerging
Fumiaki Sugahara, Contributor, 22. Cyclostomes (Lamprey and Hagfish)
CRC Press, Dec. 2021
036744447X - Cerebellum as a CNS Hub (Contemporary Clinical Neuroscience)
Yasunori Murakami; Fumiaki Sugahara, Contributor, Evolutionary and Developmental Perspectives on the Origin and Diversification of the Vertebrate Cerebellum
Springer, Nov. 2021
3030758168 - Brain Science Review 2019
Fumiaki Sugahara, Contributor, Evolution of the developmental plan for the vertebrate cerebellum, insights from cyclostomes.
KUBAPRO, Jun. 2019
4878051604 - In Situ Hybridization Methods (Neuromethods)
Fumiaki Sugahara; Yasunori Murakami; Shigeru Kuratani; Giselbert Hauptmann, Contributor, Part IV, "Gene Expression Analysis of Lamprey Embryos"
Humana Press, Feb. 2015
1493923021
Research Themes
- Evo-Devo study of cerebellum-specific neurons using cyclostomes
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2023 - 31 Mar. 2026 - Special Grant
Hyogo Medical University
Apr. 2023 - Mar. 2024 - Joint research
Apr. 2014 - Mar. 2023 - Special Grant
Hyogo Medical University
Apr. 2021 - Mar. 2022 - 円口類を用いた「第３の半規管」水平半規管獲得の進化発生学的な解明
2019 - 2022 - Research grant
Aug. 2017 - Aug. 2019 - Apr. 2017 - Mar. 2018
- Mar. 2018
- 円口類ヌタウナギ、ヤツメウナギ半規管の進化発生学的解析
2016 - 2018 - 2015 - 2017
- Apr. 2014 - Mar. 2015
- Evolutionary developmental study of the cyclostome towards acquisition of the paired nostrils.
Grant-in-Aid for Young Scientists (B)
Hyogo Medical University
2013 - 2015 - Developmental study of the naso-hypophyseal placode in cyclostomes (Lamprey and Hagfish)
Grant-in-Aid for Research Activity Start-up
The Institute of Physical and Chemical Research
2011 - 2012
Social Contribution Activities
- 滝川第二中学校 出張授業
lecturer
30 Jul. 2024 - からだに隠された進化の痕跡と、進化と病気の関係
lecturer
こうべ生涯学習カレッジ, 14 Nov. 2023 - 授業科目「グリーンサイエンス」 円口類から探る脊椎動物の進化
lecturer
ノートルダム清心女子高等学校【SHH指定校】, 2018 - 2022 - 雲雀丘学園高等学校 「職業人レクチャー」
lecturer
07 Nov. 2020 - 京都橘中学高等学校 出張授業
lecturer
28 Jan. 2020 - 授業科目「生命」 円口類から探る脊椎動物の進化
lecturer
ノートルダム清心女子高等学校【SHH指定校】, 2014 - 2017
Media Coverage
- Interview: 脊椎動物の「脳」の基本構造は５億年以上前に成立していた！
大学受験予備校・四谷学院の学部学科がわかる本|公式サイト, Nov. 2023 - 理研・東大・兵庫医科大、ヤツメウナギの内柱がヤツメウナギ現生種の系統で独自に獲得された可能性を明らかに
日本経済新聞社, 日本経済新聞, 01 Apr. 2022, Paper - 理研・神戸大・兵庫医科大・東大、脊椎動物の３つの半規管の構成要素の大部分が5億年以上前に獲得されていたことを解明
日本経済新聞社, 日本経済新聞, 06 Dec. 2018, Paper - 脳の進化的起源を解明
日本工業新聞, Fuji Sankei Business i, FBi. Science View, 17 Mar. 2016, Paper - 脳の基本構造 5億年以上前に 理研など特定
産経新聞社, The Sankei Shimbun, 2016年2月16日朝刊, 16 Feb. 2016, Paper - 脳の基本形5億年以上前に 理研と兵庫医大 原始的脊椎動物を解析
神戸新聞社, 神戸新聞, 2016年2月16日朝刊, Feb. 2016, Paper - 脊椎動物の脳基本構造 5億年以上前に完成
日本経済新聞社, 日経産業新聞〔日経テレコン21〕, 2016年2月16日朝刊, Feb. 2016, Paper - 脊椎動物 脳の基本構造 5億年前に完成
日本経済新聞社, 日本経済新聞, 2016年2月16日朝刊, Feb. 2016, Paper - 脳の基本構造 5億年前から
朝日新聞社, The Asahi Shimbun, 2016年2月16日朝刊, Feb. 2016, Paper
