Last Updated :2025/09/01
Researcher Information
Career
- Apr. 2025 - Present
The University of Osaka, Graduate School of Medicine Division of Medicine, 招へい教員 - Apr. 2025 - Present
Hyogo Medical University, 病理学 (分子病理部門) 講座, Assistant professor - Apr. 2022 - Mar. 2025
Japan Society for the Promotion of Science - Apr. 2021 - Mar. 2025
The University of Osaka, 卓越大学院プログラム (生命医科学の社会実装を推進する卓越人材の涵養), 修了 - Sep. 2021 - Mar. 2022
The University of Osaka, 学際融合を推進し社会実装を担う 次世代挑戦的研究者育成プロジェクト, 修了
Educational Background
- Apr. 2021 - Mar. 2025, The University of Osaka, Graduate School of Medicine, Division of Medicine
- Apr. 2018 - Mar. 2020, Hiroshima University, Graduate School of Biomedical Sciences, 医歯科学専攻, 修士課程
- Apr. 2014 - Mar. 2018, Kurashiki University of Science and the Arts, College of Life Science, Department of Medical Life Science
Research activity information
Paper
- 〔Major achievements〕Involvement of lncRNA MIR205HG in idiopathic pulmonary fibrosis and IL-33 regulation via Alu elements.
Takashima T; Zeng C; Murakami E; Fujiwara N; Kohara M; Nagata H; Feng Z; Sugai A; Harada Y; Ichijo R; Okuzaki D; Nojima S; Matsui T; Shintani Y; Kawai G; Hamada M; Hirose T; Nakatani K; Morii E
JCI insight, Mar. 2025
Lead - Spatial transcriptome analysis of lung squamous cell carcinoma arising from interstitial pneumonia provides insights into tumor heterogeneity
Koto Ukon; Satoshi Nojima; Daisuke Motooka; Tsuyoshi Takashima; Masaharu Kohara; Hiroki Kiyokawa; Kenji Kimura; Eriko Fukui; Shinichiro Tahara; Kansuke Kido; Takahiro Matsui; Yasushi Shintani; Daisuke Okuzaki; Eiichi Morii
Pathology - Research and Practice, Feb. 2025 - Hypoxia drives the formation of lung micropapillary adenocarcinoma-like structure through hypoxia-inducible factor-1α
Daisuke Umeda; Akikazu Harada; Daisuke Motooka; Shinichiro Tahara; Masako Kurashige; Kansuke Kido; Tsuyoshi Takashima; Hiroki Kiyokawa; Koto Ukon; Takahiro Matsui; Shinji Matsumoto; Yasushi Shintani; Daisuke Okuzaki; Akira Kikuchi; Satoshi Nojima; Eiichi Morii
Scientific Reports, Dec. 2024 - Mesothelin promotes the migration of endometrioid carcinoma and is associated with the MELF pattern
Shinichiro Tahara; Satoshi Nojima; Tsuyoshi Takashima; Daisuke Okuzaki; Eiichi Morii
Pathology - Research and Practice, Oct. 2024 - Transcriptome analysis of an AKT inhibitor-resistant endometrial cancer cell line
Takafumi Onishi; Tsuyoshi Takashima; Kazuki Shibahara; Shoji Takagi; Shinichi Tanaka; Michihiro Mori; Hirokazu Odashima; Yukihiko Osawa; Manabu Hattori
Pharmacological Reports, Apr. 2024 - Acquired AKT-inhibitor Resistance Is Mediated by ATP-binding Cassette Transporters in Endometrial Carcinoma
SHOJI TAKAGI; TAKAFUMI ONISHI; TSUYOSHI TAKASHIMA; KAZUKI SHIBAHARA; MICHIHIRO MORI
Anticancer Research, Jun. 2023 - Ovarian high‐grade serous carcinoma cells with low SMARCA4 expression and high SMARCA2 expression contribute to platinum resistance
Kansuke Kido; Satoshi Nojima; Daisuke Motooka; Yusuke Nomura; Masaharu Kohara; Kazuaki Sato; Kenji Ohshima; Shinichiro Tahara; Masako Kurashige; Daisuke Umeda; Tsuyoshi Takashima; Hiroki Kiyokawa; Koto Ukon; Takahiro Matsui; Daisuke Okuzaki; Eiichi Morii
The Journal of Pathology, May 2023 - Schlafen family member 11 indicates favorable prognosis of patients with head and neck cancer following platinum-based chemoradiotherapy
Seijiro Hamada; Satoshi Kano; Junko Murai; Takayoshi Suzuki; Nayuta Tsushima; Takatsugu Mizumachi; Masanobu Suzuki; Tsuyoshi Takashima; Daiki Taniyama; Naoya Sakamoto; Yoichiro Fujioka; Yusuke Ohba; Akihiro Homma
Frontiers in Oncology, Jan. 2023 - Essential Roles of TDO2 in Gastric Cancer: TDO2 Is Associated with Cancer Progression, Patient Survival, PD-L1 Expression, and Cancer Stem Cells
Quoc Thang Pham; Daiki Taniyama; Shintaro Akabane; Tsuyoshi Takashima; Ryota Maruyama; Yohei Sekino; Kazuhiro Sentani; Wataru Yasui; Naohide Oue
Pathobiology, 2023 - Mutually exclusive expression of EZH2 and H3K27me3 in non-small cell lung carcinoma
Takafumi Onishi; Tsuyoshi Takashima; Masako Kurashige; Kenji Ohshima; Eiichi Morii
Pathology - Research and Practice, Oct. 2022 - Prognostic impact of Schlafen 11 in bladder cancer patients treated with platinum‐based chemotherapy
Daiki Taniyama; Naoya Sakamoto; Tsuyoshi Takashima; Masahiko Takeda; Quoc Thang Pham; Shoichi Ukai; Ryota Maruyama; Kenji Harada; Takashi Babasaki; Yohei Sekino; Tetsutaro Hayashi; Kazuhiro Sentani; Yves Pommier; Junko Murai; Wataru Yasui
Cancer Science, Feb. 2022 - Establishment of oxaliplatin-resistant gastric cancer organoids: importance of myoferlin in the acquisition of oxaliplatin resistance
Kenji Harada; Naoya Sakamoto; Shoichi Ukai; Yusuke Yamamoto; Quoc Thang Pham; Daiki Taniyama; Ririno Honma; Ryota Maruyama; Tsuyoshi Takashima; Hiroshi Ota; Yuki Takemoto; Kazuaki Tanabe; Hideki Ohdan; Wataru Yasui
Gastric Cancer, Nov. 2021 - 〔Major achievements〕Schlafen 11 predicts response to platinum-based chemotherapy in gastric cancers
Tsuyoshi Takashima; Daiki Taniyama; Naoya Sakamoto; Maika Yasumoto; Ryuichi Asai; Takuya Hattori; Ririno Honma; Quoc Thang Pham; Shoichi Ukai; Ryota Maruyama; Kenji Harada; Kazuya Kuraoka; Kazuaki Tanabe; Atsuo T. Sasaki; Hideki Ohdan; Eiichi Morii; Junko Murai; Wataru Yasui
British Journal of Cancer, Jul. 2021
Lead - 〔Major achievements〕Immunohistochemical analysis of SLFN11 expression uncovers potential non-responders to DNA-damaging agents overlooked by tissue RNA-seq
Tsuyoshi Takashima; Naoya Sakamoto; Junko Murai; Daiki Taniyama; Ririno Honma; Shoichi Ukai; Ryota Maruyama; Kazuya Kuraoka; Vinodh N. Rajapakse; Yves Pommier; Wataru Yasui
Virchows Archiv, Mar. 2021
Lead - Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development
Fumiya Moribe; Momoko Nishikori; Tsuyoshi Takashima; Daiki Taniyama; Nobuyuki Onishi; Hiroshi Arima; Hiroyuki Sasanuma; Remi Akagawa; Fathi Elloumi; Shunichi Takeda; Yves Pommier; Eiichi Morii; Akifumi Takaori-Kondo; Junko Murai
PLOS ONE, Jan. 2021 - Molecular biological analysis of 5-FU-resistant gastric cancer organoids; KHDRBS3 contributes to the attainment of features of cancer stem cell
Shoichi Ukai; Ririno Honma; Naoya Sakamoto; Yusuke Yamamoto; Quoc Thang Pham; Kenji Harada; Tsuyoshi Takashima; Daiki Taniyama; Ryuichi Asai; Kaho Fukada; Kazuhito Naka; Kazuaki Tanabe; Hideki Ohdan; Wataru Yasui
Oncogene, Dec. 2020 - Uc.63+ contributes to gastric cancer progression through regulation of NF-kB signaling
Naoya Sakamoto; Yohei Sekino; Kaho Fukada; Quoc Thang Pham; Ririno Honma; Daiki Taniyama; Shoichi Ukai; Tsuyoshi Takashima; Takuya Hattori; Kazuhito Naka; Kazuaki Tanabe; Hideki Ohdan; Wataru Yasui
Gastric Cancer, Sep. 2020
Lectures, oral presentations, etc.
- 特発性肺線維症において増加するlong non-cording RNA MIR205HGはIL33発現を制御する
髙島剛志
第21回日本病理学会カンファレンス, Jul. 2025 - Involvement of lncRNA MIR205HG in idiopathic pulmonary fibrosis and regulation of IL33 via Alu elements
髙島剛志
第114回日本病理学会総会, Apr. 2025 - 病理学的所見から切りひらく特発性肺線維症の悪性化メカニズム
髙島剛志
令和6年度日本病理学会近畿支部 夏期病理セミナー「夏の学校」, Aug. 2024, [Invited] - lncRNA MIR205HGは特発性肺線維症で増加し、炎症遺伝子を制御する
髙島剛志
第113回日本病理学会総会, Mar. 2024 - 胃癌におけるSLFN11の発現はプラチナ製剤の効果反応を予測する
髙島剛志
第63回日本臨床細胞学会総会春期大会, Jun. 2022 - 胃癌におけるSLFN11の発現はプラチナ製剤のバイオマーカーとして有用である
髙島剛志
第32回消化器癌発生学会総会, Nov. 2021 - A case of endometrioid carcinoma with mucinous differentiation diagnosed as mucinous carcinoma by endometrial cytology
Tsuyoshi Takashima
The 27th Thai-Japanese Workshop in Diagnostic Cytopathology, Jan. 2020 - 胃癌におけるSLFN11の発現とDNA障害型抗がん剤との相関
髙島剛志
第78回日本癌学会総会, Sep. 2019 - 胃癌における SLFN11発現の意義
髙島剛志
第28回日本がん転移学会学術集会・総会, Jul. 2019 - ヒト正常組織及び癌組織におけるSLFN11タンパク発現の検討
髙島剛志
第108回日本病理学会総会, Apr. 2019 - KIF23 expression is frequently found in gastric cancer with intestinal mucin phenotype
髙島剛志
第77回日本癌学会総会, Sep. 2018
