清宮 健一
| 衛生薬学分野 | 教授 |
Last Updated :2024/12/13
研究者情報
学歴
研究活動情報
論文
- ナノマテリアルの健康影響
清宮 健一
J.Antibact.Antifung.Agents, 2013年, ［査読有り］, ［招待有り］ - Spinal cord trauma in a cat caused by ingestion of a splinter
Toshiyuki Tanaka; Hideo Akiyoshi; Hitoshi Shimazaki; Akinori Sato; Masahiro Inada; Ken-ichi Kiyomiya; Junichiro Shimizu; Zheng Cao; Yijyun Li; Akiyoshi Hayashi; Katsuhito Sone; Tadashi Kitai; Fumihito Ohashi
JOURNAL OF FELINE MEDICINE AND SURGERY, 2012年02月, ［査読有り］ - Detection of chromogranin A in the adrenal gland extracts of different animal species by an enzyme-linked immunosorbent assay using Thomsen-Friedenreich antigen-specific Amaranthus caudatus lectin
Hideo Akiyoshi; Shunji Sugii; Md A. Nahid; Katsuhito Sone; Toshiyuki Tanaka; Cao Zheng; Li Yijyun; Mica Aoki; Shigeo Takenaka; Terumasa Shimada; Junichiro Shimizu; Ken-ichi Kiyomiya; Fumihito Ohashi
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2011年12月, ［査読有り］ - Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain
Ming-Shyue Lee; I-Chu Tseng; Youhong Wang; Ken-ichi Kiyomiya; Michael D. Johnson; Robert B. Dickson; Chen-Yong Lin
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2007年07月 - Effect of BDNF depletion on the formation of Ruffini endings in vibrissa follicles and the survival of their mechanoreceptive neurons in trigeminal ganglion
Shigenaga Shimizu; Hiroyuki Ichikawa; Hiroshi Nakagawa; Ken-ichi Kiyomiya; Saburo Matsuo
BRAIN RESEARCH, 2007年06月 - Matriptase activation and subsequent shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells.（共著）
Kiyomiya, K; Lee, M.S; Tseng, I.C; Zuo, H; Barndt, R.J; Johnson, M.D; Dickson, R.B; Lin, C.Y
American Journal of Physiology-Cell Physiology, 2006年07月 - HAI-1 regulates activation and expression of matriptase, a membrane-bound serine protease.（共著）
Oberst M.D; Chen, L.L; Kiyomiya, K; Williams, C.A; Lee, M.S; Johnson, M.D; Dicksonm R.B; Lin, C.Y
American Journal of Physiology - Cell Physiology, 2005年08月 - Hepatocyte growth factor activator inhibitor I (HAI-I): role in matriptase function beyond a conventional inhibitor.（共著）
M Oberst; LL Chen; KI Kiyomiya; CA Williams; MS Lee; MD Johnson; RB Dickson; CY Lin
Thrombosis and haemostasis, 2005年04月 - Simultaneous activation and hepatocyte growth factor activator inhibitor 1-mediated inhibition of matriptase induced at activation foci in human mammary epithelial cells.（共著）
MS Lee; K Kiyomiya; C Benaud; RB Dickson; CY Lin
American Journal of Physiology - Cell Physiology, 2005年04月 - Correlation between nuclear action of anthracycline anticancer agents and their binding affinity to the proteasome.（共著）
KI Kiyomiya; J Satoh; H Horie; M Kurebe; H Nakagawa; S Matsuo
International Journal of Oncology, 2002年11月 - Mitochondrial cytochrome c oxidase as a target site for cephalosporin antibiotics in renal epithelial cells (LLC-PK1) and renal cortex.（共著）
K Kiyomiya; N Matsushita; M Kurebe; H Nakagawa; S Matsuo
Life Sciences, 2002年11月 - The role of the proteasome in apoptosis induced by anthracycline anticancer agents.(共著)
International Journal of Oncology, 2002年 - Ruffini ending are absent from the periodontal ligament or trkB knockout mice.（共著）
S Matsuo; H Ichikawa; Silos-Santiago, I; KI Kiyomiya; M Kurebe; JJA Arends; MF Jacquin
Somatosensory and Motor Research, 2002年 - Differences in intracellular sites of action of adriamycin in neoplastic and normal differentiated cell(共著)
KIYOMIYA K; MATSUO S; KUREBE M
Cancer Chemotherapy and Pharmacology, 2001年01月 - Mechanism of specific nuclear transport of doxorubicin : The mode of nuclear translocation of doxorubicin-proteasome complex(共著)
Cancer Research, 2001年 - Cephaloridine-induced inhibition of cytochrome coxidase activity in the mitochondria of cultured renal epithelial cells(LLC-PK1) as a possible mechanism of its nephrotoxicity(共著)
KIYOMIYA K; MATSUSHITA N; MATSUO S; KUREBE M
Toxicol. Appl. Pharmacol, 2000年09月 - Differential toxic effects of gentamicin on cultured renal epithelial cells(LLC-PK1)on application to the brush border membrane or the basolateral membrane(共著)
清宮 健一; 松下 直子; 松尾 三郎; 暮部 勝
J.Vet.Med.Sci., 2000年09月 - Roles of oxygen rodical production and lipid peroxidation in the cytotoxicity of cephaloridine on cultured renal epitholial cells(LLC-PK1).(共著)
清宮 健一; 松下 直子; 松尾 三郎; 暮部 勝
J.Vet.Med.Sci., 2000年09月 - Implanted tumor growth is suppressed and survival is prolonged in sixty percent of food-restricted mico(共著)
J Matsuzaki; R Yamaji; K Kiyomiya; M Kurebe; H Inui; Y Nakano
J.Nutr., 2000年01月 - Role of hypothermia induced by tumor necrosis factor on apoptosis and function of inflammatory neutrophils in mice(共著)
T Mizuno; Y Kannan; M Tokunaga; M Moriyama; Y Kiso; K Kusakabe; J Yamate; K Kiyomiya; T Sugano
Am.J.Physiol., 2000年01月 - Fluoride-induced ultrastructural changes in exocrine pancreas cells of rats : fluoride disrupts the export of zymogens from the rough endoplasmic reticulum(rER)(共著)
MATSUO S; NAKAGAWA H; KIYOMIYA K; KUREBE M
Arch.Toxicol, 2000年 - In situ photoaffinity labeling of proteasome with photoactive adriamycin analogue.(共著)
KIYOMIYA K; MATSUO S; KUREBE M
Biochem.Biophys.Res.Commun, 2000年 - Proprioceptive offerents survive in the masser muscle of trk C knockout mice(共著)
MATSUO S; ICHIKAWA H; SILOS‐SANTIAGO I; ARENDS J J A; HENDERSON T A; KIYOMIYA K; KUREBE M; JACQUIN M F
Neuroscience, 2000年 - Proteasome is a carrier to translocate doxorubicin from cytoplasm into nucleus. (共著)
KIYOMIYA K; MATSUO S; KUREBE M
Life Sciences, 1998年04月 - Mechanism of toxic action of fluoride in dental fluorosis : whether trimeric Goprotein participate in the disturbance of intracellular transport of secretory ameloblast exposed to fluoride(共著)
MATSUO S; KIYOMIYA K; KUREBE M
Archives of Toxicology, 1998年 - Influence of fluoride on secretory pathway of the secretory ameloblast in rat incisor tooth germs exposed to sodium fluoride (共著)
MATSUO S; INAI T; KURISU K; KIYOMIYA K; KUREBE M
Archies of Toxicology, 1996年04月 - Deodorant effect of Amenitop, antimicrobiol compound on the feces in rats and toxicological study with its administrations for a month (共著)
Applied Biological Science, 1995年 - Relation between the trans-golgi network and the golgi stack on development of the golgi apparatus of the ameloblast on developing rat molar tooth germs (共著)
S MATSUO; K KURISU; K KIYOMIYA; M KUREBE
The Anatomical Record, 1995年01月 - Changes of Lectin Staining Patlern of the Golgi Stock During Differentiation of the Ameloblastin Developing Rat Molar Tooth Germs(共著)
S MATSUO; H ICHIKAWA; K KURISU; S WAKISAKA; KI KIYOMIYA; M KUREBE
The Anatomical Recerd, 1993年06月 - Mechanism of differential cytotoxicic effects of ascorbic acid on neoplastic cells and normal differentiated cells (共著)
Toxicology Letters, 1992年 - Difference of intracellular action sites of doxorubicin in neoplastic cell and normal differentiated cell (共著)
Toxicology Letters, 1992年 - General toxicity and immunotoxicity of antitumor agents (共著)
KUREBE Masaru; KIYOMIYA Ken-ichi
Journal of Toxicological Sciences, 1991年 - アムリノンの毒性学的研究 3.ラットにおける亜急性毒性 (共著)
基礎と臨床, 1990年 - Studies on the mechanism of nephrotoxicity of aminoglycoside antibiotics: Toxic effects of aminoglycoside antibiotics on cultured renal epithelial cells from brush border membrane or basal membrane.（共著）
Japanese Journal of Pharmacology, Vol.46 (Supplement), pp. 297P, 1988年 - Ethyl Loflazepate (CM6912)に関する毒性学的研究：５．雄ビーグル犬における急性毒性
清宮 健一
基礎と臨床, 1986年03月, ［査読有り］ - Studies on the nephrotoxicity of aminoglycoside antibiotics: Effects on cultured renal epithelial cells.（共著）
Journal of Toxicological Sciences, 1986年 - Studies on the mechanism of nephrotoxicity of aminoglycoside antibiotics: Effect on brush border membranes and lysosome of renal epithelial cell in rats.（共著）
Japanese Journal of Pharmacology, 1986年 - HBKに関する毒性学的研究 8.静脈内投与によるビーグル犬慢性毒性試験 (共著)
基礎と臨床, 1986年 - HBKに関する毒性学的研究 7.筋肉内投与によるビーグル犬亜急性毒性および回復性試験 (共著)
基礎と臨床, 1986年 - Effect of fosfomycin on toxicity and antineoplastic activity of cisplatin (共著)
Toxicology Letters, 1986年 - Phorbol myristate acetate-stimulated release of cyclooxygenase products in rat pleural cells : Derivatization of prostaglandins with 9-anthryldiazomatane for fluorometric determination by high performance liquid chromatography (共著)
KIYOMIYA K; YAMAKI K; NIMURA N; KINOSHITA T; OH‐ISHI S
Prostaglandins, 1986年01月 - Involvement of arachidonic acid metabolites in acute inflammation : Detection of 6-keto-PGF1a, Thromboxan B2 and PGD2 in rat pleurisy by phorbol myristate acetate (共著)
KIYOMIYA K; OH‐ISHI S
Japan Journal of Pharmacology, 1985年 - Search of chemical mediators with the inflammatory model: (2) Involvement of arachidonic acid metabolite in rat pleurisy.（共著）
K KIYOMIYA; M KIKUCHI; M HAYASHI; O SACHIKO
Japanese Journal of Pharmacology, 1984年 - Search of chemical mediators with inflammatory model: (1) Involvement of histamine in rat pleurisy.（共著）
M KIKUCHI; K KIYOMIYA; M HAYASHI; K KAWAMURA; O SACHIKO
Japanese Journal of Pharmacology, 1984年
MISC
- Matriptase activation and subsequent shedding with HAI-I is induced by steroidal sex hormones in human prostate but not breast cancer cells
MS Lee; KI Kiyomiya; RB Dickson; CY Lin
THROMBOSIS AND HAEMOSTASIS, 2005年04月 - Correlation between nuclear action of anthracycline anticancer agents and their binding affinity to the proteasome
KI Kiyomiya; J Satoh; H Horie; M Kurebe; H Nakagawa; S Matsuo
INTERNATIONAL JOURNAL OF ONCOLOGY, 2002年11月 - Mitochondrial cytochrome c oxidase as a target site for cephalosporin antibiotics in renal epithelial cells (LLC-PK1) and renal cortex
K Kiyomiya; N Matsushita; M Kurebe; H Nakagawa; S Matsuo
LIFE SCIENCES, 2002年11月 - The role of the proteasome in apoptosis induced by anthracycline anticancer agents
KI Kiyomiya; M Kurebe; H Nakagawa; S Matsuo
INTERNATIONAL JOURNAL OF ONCOLOGY, 2002年06月 - Ruffini endings are absent from the periodontal ligament of trkB knockout mice
S Matsuo; H Ichikawa; Silos-Santiago, I; KI Kiyomiya; M Kurebe; JJA Arends; MF Jacquin
SOMATOSENSORY AND MOTOR RESEARCH, 2002年 - Mechanism of specific nuclear transport of adriamycin: The mode of nuclear translocation of adriamycin-proteasome complex
K Kiyomiya; S Matsuo; M Kurebe
CANCER RESEARCH, 2001年03月 - Differences in intracellular sites of action of Adriamycin in neoplastic and normal differentiated cells
K Kiyomiya; S Matsuo; M Kurebe
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2001年01月 - Cephaloridine-induced inhibition of cytochrome c oxidase activity in the mitochondria of cultured renal epithelial cells (LLC-PK1) as a possible mechanism of its nephrotoxicity
K Kiyomiya; N Matsushita; S Matsuo; M Kurebe
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2000年09月 - Differential toxic effects of gentamicin on cultured renal epithelial cells (LLC-PK1) on application to the brush border membrane or the basolateral membrane
K Kiyomiya; N Matsushita; S Matsuo; M Kurebe
JOURNAL OF VETERINARY MEDICAL SCIENCE, 2000年09月 - Roles of oxygen radical production and lipid peroxidation in the cytotoxicity of cephaloridine on cultured renal epithelial cells (LLC-PK1)
K Kiyomiya; N Matsushita; S Matsuo; M Kurebe
JOURNAL OF VETERINARY MEDICAL SCIENCE, 2000年09月 - In situ photoaffinity labeling of proteasome with photoactive adriamycin analogue
K Kiyomiya; S Matsuo; M Kurebe
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000年07月 - Fluoride-induced ultrastructural changes in exocrine pancreas cells of rats: fluoride disrupts the export of zymogens from the rough endoplasmic reticulum (rER)
S Matsuo; H Nakagawa; K Kiyomiya; M Kurebe
ARCHIVES OF TOXICOLOGY, 2000年02月 - Implanted tumor growth is suppressed and survival is prolonged in sixty percent of food-restricted mice
J Matsuzaki; R Yamaji; K Kiyomiya; M Kurebe; H Inui; Y Nakano
JOURNAL OF NUTRITION, 2000年01月 - Role of hypothermia induced by tumor necrosis factor on apoptosis and function of inflammatory neutrophils in mice
T Mizuno; Y Kannan; M Tokunaga; M Moriyama; Y Kiso; K Kusakabe; J Yamate; K Kiyomiya; T Sugano
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2000年01月 - Proprioceptive afferents survive in the masseter muscle of trkC knockout mice
S Matsuo; H Ichikawa; Silos-Santiago, I; JJA Arends; TA Henderson; K Kiyomiya; M Kurebe; MF Jacquin
NEUROSCIENCE, 2000年 - Mechanism of toxic action of fluoride in dental fluorosis: whether trimeric G proteins participate in the disturbance of intracellular transport of secretory ameloblast exposed to fluoride
S Matsuo; K Kiyomiya; M Kurebe
ARCHIVES OF TOXICOLOGY, 1998年12月 - Proteasome is a carrier to translocate doxorubicin from cytoplasm into nucleus
K Kiyomiya; S Matsuo; M Kurebe
LIFE SCIENCES, 1998年04月 - Influence of fluoride on secretory pathway of the secretory ameloblast in rat incisor tooth germs exposed to sodium fluoride
S Matsuo; T Inai; K Kurisu; KI Kiyomiya; M Kurebe
ARCHIVES OF TOXICOLOGY, 1996年04月 - Deodorant effect of Amenitop, antimicrobiol compound on the feces in rats and toxicological study with its administrations for a month (共著)
Applied Biological Science, 1995年 - Relation between the trans‐Golgi network and the Golgi stack on development of the Golgi apparatus of the ameloblast in developing rat molar tooth germs
Saburou Matsuo; Kojiro Kurisu; Ken‐Ichi Kiyomiya; Masaru Kurebe
The Anatomical Record, 1995年 - Effect of colchicine on the Golgi apparatus in secretory ameloblast studied by cytochemistry and ^3H-proline autoradiography in vitro
Matsuo S; Kiyomiya K; Yoshikawa A; Kurebe M
Journal of toxicological sciences, 1993年11月25日 - CHANGES OF LECTIN STAINING PATTERN OF THE GOLGI STACK DURING DIFFERENTIATION OF THE AMELOBLAST IN DEVELOPING RAT MOLAR TOOTH GERMS
S MATSUO; H ICHIKAWA; K KURISU; S WAKISAKA; KI KIYOMIYA; M KUREBE
ANATOMICAL RECORD, 1993年06月 - Mechanism of differential cytotoxicic effects of ascorbic acid on neoplastic cells and normal differentiated cells (共著)
Toxicology Letters, 1992年 - Difference of intracellular action sites of doxorubicin in neoplastic cell and normal differentiated cell (共著)
Toxicology Letters, 1992年 - GENERAL TOXICITY AND IMMUNOTOXICITY OF ANTITUMOR AGENTS
KUREBE Masaru; KIYOMIYA Ken-ichi
The Journal of Toxicological Sciences, 1991年 - RENAL TOXICITY MECHANISM OF CEPHALOSPORINS - EFFECT OF CEPHALORIDINE ON THE MITOCHONDRIA IN CULTURED LLC-PK1 CELLS
M KUREBE; KI KIYOMIYA
EUROPEAN JOURNAL OF PHARMACOLOGY, 1990年07月 - COMPARISON OF INTERACTIONS OF FOSFOMYCIN AND CISPLATIN ON CULTIVATED LYMPHOCYTES AND LEUKEMIA-CELLS
K KIYOMIYA; N SUGIYAMA; H KAWAOTO; M KUREBE
FOLIA PHARMACOLOGICA JAPONICA, 1986年06月 - INTERACTION OF FOSFOMYCIN AND CISPLATIN ON THE CULTIVATED LYMPHOCYTES OF RATS
K KIYOMIYA; N SUGIYAMA; H SASAKI; M KUREBE
FOLIA PHARMACOLOGICA JAPONICA, 1986年03月 - Effect of fosfomycin on toxicity and antineoplastic activity of cisplatin (共著)
Toxicology Letters, 1986年 - PHORBOL-MYRISTATE ACETATE-STIMULATED RELEASE OF CYCLOOXYGENASE PRODUCTS IN RAT PLEURAL CELLS - DERIVATIZATION OF PROSTAGLANDINS WITH 9-ANTHRYLDIAZOMETHANE FOR FLUOROMETRIC-DETERMINATION BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
K KIYOMIYA; K YAMAKI; N NIMURA; T KINOSHITA; S OHISHI
PROSTAGLANDINS, 1986年01月 - INVOLVEMENT OF ARACHIDONIC-ACID METABOLITES IN ACUTE-INFLAMMATION - DETECTION OF 6-KETO-PGF1-ALPHA, THROMBOXANE-B2 AND PGD2 IN RAT PLEURISY INDUCED BY PHORBOL-MYRISTATE ACETATE
K KIYOMIYA; S OHISHI
JAPANESE JOURNAL OF PHARMACOLOGY, 1985年 - EFFECT OF SOME AGENTS ON THE BINDING OF CORTISOL TO THE STEROID-RECEPTOR OF SMALL INTESTINAL-MUCOSA
M KUREBE; T HIRANUMA; K KIYOMIYA; S OHISHI
FOLIA PHARMACOLOGICA JAPONICA, 1982年
書籍等出版物
- 図解 薬害・副作用学
清宮 健一, 共著
南山堂, 2013年08月 - 第5版 衛生薬学－健康と環境ｰ
清宮 健一, 共著
丸善出版, 2013年03月 - 薬剤面談トレーニング帳
清宮 健一, 共著
化学同人, 2012年03月 - コンパス衛生薬学
清宮 健一, 共著
南江堂, 2011年03月 - 処方解析トレーニング帳
清宮 健一, 共著
化学同人, 2010年03月 - 薬理学・毒性学実習書
清宮 健一, 共著
文英堂, 2008年03月 - トキシコロジー用語集(共著)
日本毒科学会, 1993年 - Effect of cortisol and estradiol-17β on metabolism and cytotoxicity of aflatoxin B1in intestinal-mucosal cells(共著)
共著
Microsomes,drugoxidations,and toxicity, 1982年 - Effect of cortisol and estradiol-17β on metabolism and cytotoxicity of aflatoxin B1in intestinal-mucosal cells(共著)
Microsomes,drugoxidations,and toxicity, 1982年
講演・口頭発表等
- 食の安全・安心について（化学物質、医薬品などによる食品汚染）
清宮 健一
第41回 日本毒性学会学術年会 市民公開セミナー, 2014年07月 - 薬物乱用について
清宮 健一
第48回 神戸市学校保健大会, 2013年10月 - 食の安全・安心について－化学物質，医薬品などによる食品汚染ー
清宮 健一
兵庫医療 大学地域連携実践センター 公開講座, 2013年06月 - ナノマテリアルのリスク評価法の確立について
清宮 健一
平成23年度日本小動物獣医学会, 2011年11月 - 知っておきたいがんの基礎知識－がんととう付き合うか－
清宮 健一
文部科学省「戦略的大学連携支援事業」ポーアイ4大学による連携事業・地域交流プロジェクト, 2010年01月 - アンスラサイクリンの標的分子と作用発現
清宮 健一
第6回大阪府立大学・大阪府立成人病センター合同セミナー, 2007年06月 - アポトーシスにおけるプロテアソームの役割
清宮 健一
第134回日本獣医学会学術集会, 2002年09月 - アンスラサイクリン系制癌剤の標的分子への親和性と作用との関係
清宮 健一
アストラゼネカ社・リサーチグラント2001受賞式講演, 2001年12月 - 癌細胞におけるプロテアソームの役割
清宮 健一
第130回日本獣医学会学術集会, 2001年10月
