Paper

• Torsion of Metastatic Ovarian Tumor Originating From Sigmoid Colon Cancer.
  Maika Uenae; Tomoyuki Sasano; Mari Tomiie; Yoshimi Miyagi; Akihiro Moriyama
  Cureus, Apr. 2025
• Roles of C-reactive protein and LOX-1 on cancer and myeloid-derived suppressor cells in the progression of uterine cervical cancer.
  Michihide Maeda; Seiji Mabuchi; Takashi Akazawa; Yu Mizote; Tomoyuki Sasano; Naoko Komura; Mina Sakata; Tsuyoshi Takiuchi; Shinya Matsuzaki; Tsuyoshi Hisa; Harumi Nakamura; Tomoya Ekawa; Shoji Kamiura; Tadashi Kimura; Hideaki Tahara
  Scientific reports, Mar. 2025
• Trends in incidence and hormonal management of endometrial cancer during potentially reproductive age in Japan: a population-based study.
  Tomoyuki Sasano; Seiji Mabuchi; Naoko Komura; Mina Sakata; Shoji Kamiura; Toshitaka Morishima; Isao Miyashiro
  International journal of clinical oncology, Jul. 2024
• Population-Based Survival Analysis of Stage IVB Small-Cell Neuroendocrine Carcinoma in Comparison to Major Histological Subtypes of Cervical Cancer.
  Seiji Mabuchi; Naoko Komura; Tomoyuki Sasano; Mina Sakata; Shinya Matsuzaki; Tsuyoshi Hisa; Shoji Kamiura; Toshitaka Morishima; Isao Miyashiro
  Current oncology (Toronto, Ont.), Oct. 2023
• Evaluation of survival outcomes between minimally invasive and open surgery in the treatment of early-stage endometrial cancer: a population-based study in Osaka Japan.
  Tomoyuki Sasano; Seiji Mabuchi; Naoko Komura; Michihide Maeda; Shoji Kamiura; Toshitaka Morishima; Isao Miyashiro
  Japanese journal of clinical oncology, Aug. 2023
• Comparison of the Survival Outcomes of Minimally Invasive Surgery with Open Surgery in Patients with Uterine-Confined and Node-Negative Cervical Cancer: A Population-Based Study.
  Seiji Mabuchi; Tomoyuki Sasano; Naoko Komura; Michihide Maeda; Shinya Matsuzaki; Tsuyoshi Hisa; Shoji Kamiura; Toshitaka Morishima; Isao Miyashiro
  Cancers, May 2023
• Laboratory Findings of Benign Convulsions With Mild Gastroenteritis: A Meta-Analysis.
  Yoshifumi Miyagi; Tomoyuki Sasano; Kentoku Kin
  Cureus, Mar. 2023
• Twenty-five-year mortality trends of four major histological subtypes of cervical cancer: a population-based study using the Osaka cancer registry data.
  Naoko Komura; Seiji Mabuchi; Tomoyuki Sasano; Shoji Kamiura; Toshitaka Morishima; Isao Miyashiro
  Frontiers in oncology, 2023
• Platelets Increase the Expression of PD-L1 in Ovarian Cancer.
  Min Soon Cho; Hani Lee; Ricardo Gonzalez-Delgado; Dan Li; Tomoyuki Sasano; Wendolyn Carlos-Alcalde; Qing Ma; Jinsong Liu; Anil K Sood; Vahid Afshar-Kharghan
  Cancers, May 2022
• Hyponatremia and Recurrent Febrile Seizures During Febrile Episodes: A Meta-Analysis.
  Yoshifumi Miyagi; Tomoyuki Sasano; Hiroyuki Kato; Kentoku Kin
  Cureus, Apr. 2022
• Podoplanin promotes tumor growth, platelet aggregation, and venous thrombosis in murine models of ovarian cancer.
  Tomoyuki Sasano; Ricardo Gonzalez-Delgado; Nina M Muñoz; Wendolyn Carlos-Alcade; Min Soon Cho; Rahul A Sheth; Anil K Sood; Vahid Afshar-Kharghan
  Journal of thrombosis and haemostasis : JTH, Jan. 2022
• Myeloid-Derived Suppressor Cells as Therapeutic Targets in Uterine Cervical and Endometrial Cancers.
  Seiji Mabuchi; Tomoyuki Sasano
  Cells, Apr. 2021
• The effect of platelet G proteins on platelet extravasation and tumor growth in the murine model of ovarian cancer.
  Min Soon Cho; Jiasong Li; Ricardo Gonzalez-Delgado; Hani Lee; Matthew Vasquez; Tiancheng He; Yunjie He; Kai Liu; Tomoyuki Sasano; Bernd Nürnberg; Anil K Sood; Stephen T C Wong; Vahid Afshar-Kharghan
  Blood advances, Apr. 2021
• Targeting Myeloid-Derived Suppressor Cells in Ovarian Cancer.
  Seiji Mabuchi; Tomoyuki Sasano; Naoko Komura
  Cells, Feb. 2021
• Prognostic significance of bone marrow FDG uptake in patients with gynecological cancer.
  Kotaro Shimura; Seiji Mabuchi; Naoko Komura; Eriko Yokoi; Katsumi Kozasa; Tomoyuki Sasano; Mahiru Kawano; Yuri Matsumoto; Tadashi Watabe; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Jun Hatazawa; Tadashi Kimura
  Scientific reports, Jan. 2021
• The role of myeloid-derived suppressor cells in increasing cancer stem-like cells and promoting PD-L1 expression in epithelial ovarian cancer.
  Naoko Komura; Seiji Mabuchi; Kotaro Shimura; Eriko Yokoi; Katsumi Kozasa; Hiromasa Kuroda; Ryoko Takahashi; Tomoyuki Sasano; Mahiru Kawano; Yuri Matsumoto; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Tadashi Kimura
  Cancer immunology, immunotherapy : CII, Dec. 2020
• Pretreatment tumor-related leukocytosis misleads positron emission tomography-computed tomography during lymph node staging in gynecological malignancies.
  Seiji Mabuchi; Naoko Komura; Tomoyuki Sasano; Kotaro Shimura; Eriko Yokoi; Katsumi Kozasa; Hiromasa Kuroda; Ryoko Takahashi; Mahiru Kawano; Yuri Matsumoto; Hiroki Kato; Jun Hatazawa; Tadashi Kimura
  Nature communications, Mar. 2020
• Lurbinectedin (PM01183), a selective inhibitor of active transcription, effectively eliminates both cancer cells and cancer stem cells in preclinical models of uterine cervical cancer.
  Eriko Yokoi; Seiji Mabuchi; Kotaro Shimura; Naoko Komura; Katsumi Kozasa; Hiromasa Kuroda; Ryoko Takahashi; Tomoyuki Sasano; Mahiru Kawano; Yuri Matsumoto; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Tadashi Kimura
  Investigational new drugs, Oct. 2019
• Estrogen stimulates female cancer progression by inducing myeloid-derived suppressive cells: investigations on pregnant and non-pregnant experimental models.
  Katsumi Kozasa; Seiji Mabuchi; Yuri Matsumoto; Hiromasa Kuroda; Eriko Yokoi; Naoko Komura; Mahiru Kawano; Ryoko Takahashi; Tomoyuki Sasano; Kotaro Shimura; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Kazunori Nagasaka; Tadashi Kimura
  Oncotarget, Mar. 2019
• The role of myeloid-derived suppressor cells in endometrial cancer displaying systemic inflammatory response: clinical and preclinical investigations.
  Eriko Yokoi; Seiji Mabuchi; Naoko Komura; Kotaro Shimura; Hiromasa Kuroda; Katsumi Kozasa; Ryoko Takahashi; Tomoyuki Sasano; Mahiru Kawano; Yuri Matsumoto; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Tadashi Kimura
  Oncoimmunology, 2019
• Premetastatic niche and tumor-related leukocytosis: a close relationship that cannot be ignored in uterine cancer patients.
  Seiji Mabuchi; Tomoyuki Sasano; Naoko Komura
  Oncotarget, Dec. 2018
• Prostaglandin E2 produced by myeloid-derived suppressive cells induces cancer stem cells in uterine cervical cancer.
  Hiromasa Kuroda; Seiji Mabuchi; Eriko Yokoi; Naoko Komura; Katsumi Kozasa; Yuri Matsumoto; Mahiru Kawano; Ryoko Takahashi; Tomoyuki Sasano; Kotaro Shimura; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Eiichi Morii; Tadashi Kimura
  Oncotarget, Nov. 2018
• The Highly Metastatic Nature of Uterine Cervical/Endometrial Cancer Displaying Tumor-Related Leukocytosis: Clinical and Preclinical Investigations.
  Tomoyuki Sasano; Seiji Mabuchi; Katsumi Kozasa; Hiromasa Kuroda; Mahiru Kawano; Ryoko Takahashi; Naoko Komura; Eriko Yokoi; Yuri Matsumoto; Kae Hashimoto; Kenjiro Sawada; Eiichi Morii; Tadashi Kimura
  Clinical cancer research : an official journal of the American Association for Cancer Research, Aug. 2018
• Comparison of clinical utility between neutrophil count and neutrophil-lymphocyte ratio in patients with ovarian cancer: a single institutional experience and a literature review.
  Naoko Komura; Seiji Mabuchi; Eriko Yokoi; Katsumi Kozasa; Hiromasa Kuroda; Tomoyuki Sasano; Yuri Matsumoto; Tadashi Kimura
  International journal of clinical oncology, Feb. 2018
• Effect of Japanese Kampo Medicine Therapy for Menopausal Symptoms after Treatment of Gynecological Malignancy.
  Akihiko Yoshimura; Kenjiro Sawada; Tomoyuki Sasano; Hiromasa Kuroda; Katsumi Kozasa; Erika Nakatsuka; Koji Nakamura; Kae Hashimoto; Seiji Mabuchi; Tadashi Kimura
  Obstetrics and gynecology international, 2018
• Comparison of clinical utilities of the platelet count and platelet-lymphocyte ratio for predicting survival in patients with cervical cancer: a single institutional study and literature review.
  Katsumi Kozasa; Seiji Mabuchi; Naoko Komura; Eriko Yokoi; Kuroda Hiromasa; Tomoyuki Sasano; Mahiru Kawano; Yuri Matsumoto; Eiji Kobayashi; Tadashi Kimura
  Oncotarget, Aug. 2017
• Predictors of Survival in Patients With FIGO Stage IVB Cervical Cancer.
  Tomoyuki Sasano; Seiji Mabuchi; Hiromasa Kuroda; Ryoko Takahashi; Katsumi Kozasa; Fumiaki Isohashi; Yasuo Yoshioka; Kazuhiko Ogawa; Tadashi Kimura
  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Mar. 2016
• Two consecutive pregnancies in a patient with paroxysmal nocturnal haemoglobinuria treated with anticoagulant therapy at different doses.
  Tomoyuki Sasano; Takuji Tomimatsu; Jun-Ichi Nishimura; Itaru Matsumura; Yuzuru Kanakura; Tadashi Kimura
  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, Jan. 2016
• Preclinical Investigations of PM01183 (Lurbinectedin) as a Single Agent or in Combination with Other Anticancer Agents for Clear Cell Carcinoma of the Ovary.
  Ryoko Takahashi; Seiji Mabuchi; Mahiru Kawano; Tomoyuki Sasano; Yuri Matsumoto; Hiromasa Kuroda; Katsumi Kozasa; Kae Hashimoto; Kenjiro Sawada; Tadashi Kimura
  PloS one, 2016
• Efficacies of uterine artery embolization for symptomatic uterine fibroids using gelatin sponge: a single-center experience and literature review.
  Aska Toda; Kenjiro Sawada; Keigo Osuga; Noboru Maeda; Hiroki Higashihara; Tomoyuki Sasano; Noriyuki Tomiyama; Tadashi Kimura
  International journal of women's health, 2016
• The significance of G-CSF expression and myeloid-derived suppressor cells in the chemoresistance of uterine cervical cancer.
  Mahiru Kawano; Seiji Mabuchi; Yuri Matsumoto; Tomoyuki Sasano; Ryoko Takahashi; Hiromasa Kuroda; Katsumi Kozasa; Kae Hashimoto; Aki Isobe; Kenjiro Sawada; Toshimitsu Hamasaki; Eiichi Morii; Tadashi Kimura
  Scientific reports, Dec. 2015
• The significance of lymphatic space invasion and its association with vascular endothelial growth factor-C expression in ovarian cancer.
  Takeshi Hisamatsu; Seiji Mabuchi; Tomoyuki Sasano; Hiromasa Kuroda; Ryoko Takahashi; Yuri Matsumoto; Mahiru Kawano; Katsumi Kozasa; Kei Takahashi; Kenjiro Sawada; Koji Matsuo; Yutaka Tamada; Eiichi Morii; Yasuhiko Kitadai; Tadashi Kimura
  Clinical & experimental metastasis, Dec. 2015
• Prognostic Significance of Pretreatment Thrombocytosis in Cervical Cancer Patients Treated With Definitive Radiotherapy.
  Mahiru Kawano; Seiji Mabuchi; Yuri Matsumoto; Tomoyuki Sasano; Ryoko Takahashi; Hiromasa Kuroda; Katsumi Kozasa; Fumiaki Isohashi; Kazuhiko Ogawa; Tadashi Kimura
  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Nov. 2015
• Real-time tissue sonoelastography for early response monitoring in cervical cancer patients treated with definitive chemoradiotherapy: preliminary results.
  Seiji Mabuchi; Tomoyuki Sasano; Hiromasa Kuroda; Ryoko Takahashi; Satoshi Nakagawa; Tadashi Kimura
  Journal of medical ultrasonics (2001), Jul. 2015
• Preclinical Efficacy for AKT Targeting in Clear Cell Carcinoma of the Ovary.
  Tomoyuki Sasano; Seiji Mabuchi; Hiromasa Kuroda; Mahiru Kawano; Yuri Matsumoto; Ryoko Takahashi; Takeshi Hisamatsu; Kenjiro Sawada; Kae Hashimoto; Aki Isobe; Joseph R Testa; Tadashi Kimura
  Molecular cancer research : MCR, Apr. 2015
• The PI3K/AKT/mTOR pathway as a therapeutic target in ovarian cancer.
  Seiji Mabuchi; Hiromasa Kuroda; Ryoko Takahashi; Tomoyuki Sasano
  Gynecologic oncology, Apr. 2015
• Prognostic significance of systemic neutrophil and leukocyte alterations in surgically treated endometrial cancer patients: a monoinstitutional study.
  Ryoko Takahashi; Seiji Mabuchi; Mahiru Kawano; Tomoyuki Sasano; Yuri Matsumoto; Hiromasa Kuroda; Takeshi Hisamatsu; Katsumi Kozasa; Kenjiro Sawada; Toshimitsu Hamasaki; Tadashi Kimura
  Gynecologic oncology, Apr. 2015
• [Treatment of ovarian clear cell carcinoma].
  Seiji Mabuchi; Ryoko Takahashi; Tomoyuki Sasano; Hiromasa Kuroda; Tadashi Kimura
  Gan to kagaku ryoho. Cancer & chemotherapy, Feb. 2015
• First two cases of primary carcinoma of the vagina successfully treated with concurrent weekly carboplatin plus paclitaxel, external beam radiotherapy and high-dose-rate interstitial brachytherapy: a case report and published work review.
  Seiji Mabuchi; Mahiru Kawano; Fumiaki Isohashi; Hiromasa Kuroda; Tomoyuki Sasano; Tadashi Kimura
  The journal of obstetrics and gynaecology research, Jan. 2015
• Uterine cervical cancer displaying tumor-related leukocytosis: a distinct clinical entity with radioresistant feature.
  Seiji Mabuchi; Yuri Matsumoto; Mahiru Kawano; Kazumasa Minami; Yuji Seo; Tomoyuki Sasano; Ryoko Takahashi; Hiromasa Kuroda; Takeshi Hisamatsu; Aiko Kakigano; Masami Hayashi; Kenjiro Sawada; Toshimitsu Hamasaki; Eiichi Morii; Hirohisa Kurachi; Nariaki Matsuura; Tadashi Kimura
  Journal of the National Cancer Institute, Jul. 2014
• Combination treatment with trabectedin and irinotecan or topotecan has synergistic effects against ovarian clear cell carcinoma cells.
  Mahiru Kawano; Seiji Mabuchi; Toshiko Kishimoto; Takeshi Hisamatsu; Yuri Matsumoto; Tomoyuki Sasano; Ryoko Takahashi; Kenjiro Sawada; Kazuhiro Takahashi; Toshifumi Takahashi; Toshimitsu Hamasaki; Tadashi Kimura
  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Jun. 2014
• [IV. Targeted therapies for epithelial ovarian cancer].
  Seiji Mabuchi; Tomoyuki Sasano; Mahiru Kawano; Tadashi Kimura
  Gan to kagaku ryoho. Cancer & chemotherapy, Feb. 2014
• Reirradiation using high-dose-rate interstitial brachytherapy for locally recurrent cervical cancer: a single institutional experience.
  Seiji Mabuchi; Ryoko Takahashi; Fumiaki Isohashi; Takeshi Yokoi; Mika Okazawa; Tomoyuki Sasano; Shintaroh Maruoka; Makoto Anzai; Yasuo Yoshioka; Kazuhiko Ogawa; Tadashi Kimura
  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Jan. 2014
• Utility of serum squamous cell carcinoma antigen levels at the time of recurrent cervical cancer diagnosis in determining the optimal treatment choice.
  Kotaro Shimura; Seiji Mabuchi; Takeshi Yokoi; Tomoyuki Sasano; Kenjirou Sawada; Toshimitsu Hamasaki; Tadashi Kimura
  Journal of gynecologic oncology, Oct. 2013
• Potential role of mTORC2 as a therapeutic target in clear cell carcinoma of the ovary.
  Takeshi Hisamatsu; Seiji Mabuchi; Yuri Matsumoto; Mahiru Kawano; Tomoyuki Sasano; Ryoko Takahashi; Kenjiro Sawada; Kimihiko Ito; Hirohisa Kurachi; Russell J Schilder; Joseph R Testa; Tadashi Kimura
  Molecular cancer therapeutics, Jul. 2013
• Impact of the addition of concurrent chemotherapy to pelvic radiotherapy in surgically treated stage IB1-IIB cervical cancer patients with intermediate-risk or high-risk factors: a 13-year experience.
  Mika Okazawa; Seiji Mabuchi; Fumiaki Isohashi; Osamu Suzuki; Yasuo Yoshioka; Tomoyuki Sasano; Yukinobu Ohta; Shoji Kamiura; Kazuhiko Ogawa; Tadashi Kimura
  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Mar. 2013