Last Updated :2025/08/30
Research activity information
Paper
- Torsion of Metastatic Ovarian Tumor Originating From Sigmoid Colon Cancer.
Maika Uenae; Tomoyuki Sasano; Mari Tomiie; Yoshimi Miyagi; Akihiro Moriyama
Cureus, Apr. 2025 - Roles of C-reactive protein and LOX-1 on cancer and myeloid-derived suppressor cells in the progression of uterine cervical cancer.
Michihide Maeda; Seiji Mabuchi; Takashi Akazawa; Yu Mizote; Tomoyuki Sasano; Naoko Komura; Mina Sakata; Tsuyoshi Takiuchi; Shinya Matsuzaki; Tsuyoshi Hisa; Harumi Nakamura; Tomoya Ekawa; Shoji Kamiura; Tadashi Kimura; Hideaki Tahara
Scientific reports, Mar. 2025 - Trends in incidence and hormonal management of endometrial cancer during potentially reproductive age in Japan: a population-based study.
Tomoyuki Sasano; Seiji Mabuchi; Naoko Komura; Mina Sakata; Shoji Kamiura; Toshitaka Morishima; Isao Miyashiro
International journal of clinical oncology, Jul. 2024 - Population-Based Survival Analysis of Stage IVB Small-Cell Neuroendocrine Carcinoma in Comparison to Major Histological Subtypes of Cervical Cancer.
Seiji Mabuchi; Naoko Komura; Tomoyuki Sasano; Mina Sakata; Shinya Matsuzaki; Tsuyoshi Hisa; Shoji Kamiura; Toshitaka Morishima; Isao Miyashiro
Current oncology (Toronto, Ont.), Oct. 2023 - Evaluation of survival outcomes between minimally invasive and open surgery in the treatment of early-stage endometrial cancer: a population-based study in Osaka Japan.
Tomoyuki Sasano; Seiji Mabuchi; Naoko Komura; Michihide Maeda; Shoji Kamiura; Toshitaka Morishima; Isao Miyashiro
Japanese journal of clinical oncology, Aug. 2023 - Comparison of the Survival Outcomes of Minimally Invasive Surgery with Open Surgery in Patients with Uterine-Confined and Node-Negative Cervical Cancer: A Population-Based Study.
Seiji Mabuchi; Tomoyuki Sasano; Naoko Komura; Michihide Maeda; Shinya Matsuzaki; Tsuyoshi Hisa; Shoji Kamiura; Toshitaka Morishima; Isao Miyashiro
Cancers, May 2023 - Laboratory Findings of Benign Convulsions With Mild Gastroenteritis: A Meta-Analysis.
Yoshifumi Miyagi; Tomoyuki Sasano; Kentoku Kin
Cureus, Mar. 2023 - Twenty-five-year mortality trends of four major histological subtypes of cervical cancer: a population-based study using the Osaka cancer registry data.
Naoko Komura; Seiji Mabuchi; Tomoyuki Sasano; Shoji Kamiura; Toshitaka Morishima; Isao Miyashiro
Frontiers in oncology, 2023 - Platelets Increase the Expression of PD-L1 in Ovarian Cancer.
Min Soon Cho; Hani Lee; Ricardo Gonzalez-Delgado; Dan Li; Tomoyuki Sasano; Wendolyn Carlos-Alcalde; Qing Ma; Jinsong Liu; Anil K Sood; Vahid Afshar-Kharghan
Cancers, May 2022 - Hyponatremia and Recurrent Febrile Seizures During Febrile Episodes: A Meta-Analysis.
Yoshifumi Miyagi; Tomoyuki Sasano; Hiroyuki Kato; Kentoku Kin
Cureus, Apr. 2022 - Podoplanin promotes tumor growth, platelet aggregation, and venous thrombosis in murine models of ovarian cancer.
Tomoyuki Sasano; Ricardo Gonzalez-Delgado; Nina M Muñoz; Wendolyn Carlos-Alcade; Min Soon Cho; Rahul A Sheth; Anil K Sood; Vahid Afshar-Kharghan
Journal of thrombosis and haemostasis : JTH, Jan. 2022 - Myeloid-Derived Suppressor Cells as Therapeutic Targets in Uterine Cervical and Endometrial Cancers.
Seiji Mabuchi; Tomoyuki Sasano
Cells, Apr. 2021 - The effect of platelet G proteins on platelet extravasation and tumor growth in the murine model of ovarian cancer.
Min Soon Cho; Jiasong Li; Ricardo Gonzalez-Delgado; Hani Lee; Matthew Vasquez; Tiancheng He; Yunjie He; Kai Liu; Tomoyuki Sasano; Bernd Nürnberg; Anil K Sood; Stephen T C Wong; Vahid Afshar-Kharghan
Blood advances, Apr. 2021 - Targeting Myeloid-Derived Suppressor Cells in Ovarian Cancer.
Seiji Mabuchi; Tomoyuki Sasano; Naoko Komura
Cells, Feb. 2021 - Prognostic significance of bone marrow FDG uptake in patients with gynecological cancer.
Kotaro Shimura; Seiji Mabuchi; Naoko Komura; Eriko Yokoi; Katsumi Kozasa; Tomoyuki Sasano; Mahiru Kawano; Yuri Matsumoto; Tadashi Watabe; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Jun Hatazawa; Tadashi Kimura
Scientific reports, Jan. 2021 - The role of myeloid-derived suppressor cells in increasing cancer stem-like cells and promoting PD-L1 expression in epithelial ovarian cancer.
Naoko Komura; Seiji Mabuchi; Kotaro Shimura; Eriko Yokoi; Katsumi Kozasa; Hiromasa Kuroda; Ryoko Takahashi; Tomoyuki Sasano; Mahiru Kawano; Yuri Matsumoto; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Tadashi Kimura
Cancer immunology, immunotherapy : CII, Dec. 2020 - Pretreatment tumor-related leukocytosis misleads positron emission tomography-computed tomography during lymph node staging in gynecological malignancies.
Seiji Mabuchi; Naoko Komura; Tomoyuki Sasano; Kotaro Shimura; Eriko Yokoi; Katsumi Kozasa; Hiromasa Kuroda; Ryoko Takahashi; Mahiru Kawano; Yuri Matsumoto; Hiroki Kato; Jun Hatazawa; Tadashi Kimura
Nature communications, Mar. 2020 - Lurbinectedin (PM01183), a selective inhibitor of active transcription, effectively eliminates both cancer cells and cancer stem cells in preclinical models of uterine cervical cancer.
Eriko Yokoi; Seiji Mabuchi; Kotaro Shimura; Naoko Komura; Katsumi Kozasa; Hiromasa Kuroda; Ryoko Takahashi; Tomoyuki Sasano; Mahiru Kawano; Yuri Matsumoto; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Tadashi Kimura
Investigational new drugs, Oct. 2019 - Estrogen stimulates female cancer progression by inducing myeloid-derived suppressive cells: investigations on pregnant and non-pregnant experimental models.
Katsumi Kozasa; Seiji Mabuchi; Yuri Matsumoto; Hiromasa Kuroda; Eriko Yokoi; Naoko Komura; Mahiru Kawano; Ryoko Takahashi; Tomoyuki Sasano; Kotaro Shimura; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Kazunori Nagasaka; Tadashi Kimura
Oncotarget, Mar. 2019 - The role of myeloid-derived suppressor cells in endometrial cancer displaying systemic inflammatory response: clinical and preclinical investigations.
Eriko Yokoi; Seiji Mabuchi; Naoko Komura; Kotaro Shimura; Hiromasa Kuroda; Katsumi Kozasa; Ryoko Takahashi; Tomoyuki Sasano; Mahiru Kawano; Yuri Matsumoto; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Tadashi Kimura
Oncoimmunology, 2019 - Premetastatic niche and tumor-related leukocytosis: a close relationship that cannot be ignored in uterine cancer patients.
Seiji Mabuchi; Tomoyuki Sasano; Naoko Komura
Oncotarget, Dec. 2018 - Prostaglandin E2 produced by myeloid-derived suppressive cells induces cancer stem cells in uterine cervical cancer.
Hiromasa Kuroda; Seiji Mabuchi; Eriko Yokoi; Naoko Komura; Katsumi Kozasa; Yuri Matsumoto; Mahiru Kawano; Ryoko Takahashi; Tomoyuki Sasano; Kotaro Shimura; Michiko Kodama; Kae Hashimoto; Kenjiro Sawada; Eiichi Morii; Tadashi Kimura
Oncotarget, Nov. 2018 - The Highly Metastatic Nature of Uterine Cervical/Endometrial Cancer Displaying Tumor-Related Leukocytosis: Clinical and Preclinical Investigations.
Tomoyuki Sasano; Seiji Mabuchi; Katsumi Kozasa; Hiromasa Kuroda; Mahiru Kawano; Ryoko Takahashi; Naoko Komura; Eriko Yokoi; Yuri Matsumoto; Kae Hashimoto; Kenjiro Sawada; Eiichi Morii; Tadashi Kimura
Clinical cancer research : an official journal of the American Association for Cancer Research, Aug. 2018 - Comparison of clinical utility between neutrophil count and neutrophil-lymphocyte ratio in patients with ovarian cancer: a single institutional experience and a literature review.
Naoko Komura; Seiji Mabuchi; Eriko Yokoi; Katsumi Kozasa; Hiromasa Kuroda; Tomoyuki Sasano; Yuri Matsumoto; Tadashi Kimura
International journal of clinical oncology, Feb. 2018 - Effect of Japanese Kampo Medicine Therapy for Menopausal Symptoms after Treatment of Gynecological Malignancy.
Akihiko Yoshimura; Kenjiro Sawada; Tomoyuki Sasano; Hiromasa Kuroda; Katsumi Kozasa; Erika Nakatsuka; Koji Nakamura; Kae Hashimoto; Seiji Mabuchi; Tadashi Kimura
Obstetrics and gynecology international, 2018 - Comparison of clinical utilities of the platelet count and platelet-lymphocyte ratio for predicting survival in patients with cervical cancer: a single institutional study and literature review.
Katsumi Kozasa; Seiji Mabuchi; Naoko Komura; Eriko Yokoi; Kuroda Hiromasa; Tomoyuki Sasano; Mahiru Kawano; Yuri Matsumoto; Eiji Kobayashi; Tadashi Kimura
Oncotarget, Aug. 2017 - Predictors of Survival in Patients With FIGO Stage IVB Cervical Cancer.
Tomoyuki Sasano; Seiji Mabuchi; Hiromasa Kuroda; Ryoko Takahashi; Katsumi Kozasa; Fumiaki Isohashi; Yasuo Yoshioka; Kazuhiko Ogawa; Tadashi Kimura
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Mar. 2016 - Two consecutive pregnancies in a patient with paroxysmal nocturnal haemoglobinuria treated with anticoagulant therapy at different doses.
Tomoyuki Sasano; Takuji Tomimatsu; Jun-Ichi Nishimura; Itaru Matsumura; Yuzuru Kanakura; Tadashi Kimura
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, Jan. 2016 - Preclinical Investigations of PM01183 (Lurbinectedin) as a Single Agent or in Combination with Other Anticancer Agents for Clear Cell Carcinoma of the Ovary.
Ryoko Takahashi; Seiji Mabuchi; Mahiru Kawano; Tomoyuki Sasano; Yuri Matsumoto; Hiromasa Kuroda; Katsumi Kozasa; Kae Hashimoto; Kenjiro Sawada; Tadashi Kimura
PloS one, 2016 - Efficacies of uterine artery embolization for symptomatic uterine fibroids using gelatin sponge: a single-center experience and literature review.
Aska Toda; Kenjiro Sawada; Keigo Osuga; Noboru Maeda; Hiroki Higashihara; Tomoyuki Sasano; Noriyuki Tomiyama; Tadashi Kimura
International journal of women's health, 2016 - The significance of G-CSF expression and myeloid-derived suppressor cells in the chemoresistance of uterine cervical cancer.
Mahiru Kawano; Seiji Mabuchi; Yuri Matsumoto; Tomoyuki Sasano; Ryoko Takahashi; Hiromasa Kuroda; Katsumi Kozasa; Kae Hashimoto; Aki Isobe; Kenjiro Sawada; Toshimitsu Hamasaki; Eiichi Morii; Tadashi Kimura
Scientific reports, Dec. 2015 - The significance of lymphatic space invasion and its association with vascular endothelial growth factor-C expression in ovarian cancer.
Takeshi Hisamatsu; Seiji Mabuchi; Tomoyuki Sasano; Hiromasa Kuroda; Ryoko Takahashi; Yuri Matsumoto; Mahiru Kawano; Katsumi Kozasa; Kei Takahashi; Kenjiro Sawada; Koji Matsuo; Yutaka Tamada; Eiichi Morii; Yasuhiko Kitadai; Tadashi Kimura
Clinical & experimental metastasis, Dec. 2015 - Prognostic Significance of Pretreatment Thrombocytosis in Cervical Cancer Patients Treated With Definitive Radiotherapy.
Mahiru Kawano; Seiji Mabuchi; Yuri Matsumoto; Tomoyuki Sasano; Ryoko Takahashi; Hiromasa Kuroda; Katsumi Kozasa; Fumiaki Isohashi; Kazuhiko Ogawa; Tadashi Kimura
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Nov. 2015 - Real-time tissue sonoelastography for early response monitoring in cervical cancer patients treated with definitive chemoradiotherapy: preliminary results.
Seiji Mabuchi; Tomoyuki Sasano; Hiromasa Kuroda; Ryoko Takahashi; Satoshi Nakagawa; Tadashi Kimura
Journal of medical ultrasonics (2001), Jul. 2015 - Preclinical Efficacy for AKT Targeting in Clear Cell Carcinoma of the Ovary.
Tomoyuki Sasano; Seiji Mabuchi; Hiromasa Kuroda; Mahiru Kawano; Yuri Matsumoto; Ryoko Takahashi; Takeshi Hisamatsu; Kenjiro Sawada; Kae Hashimoto; Aki Isobe; Joseph R Testa; Tadashi Kimura
Molecular cancer research : MCR, Apr. 2015 - The PI3K/AKT/mTOR pathway as a therapeutic target in ovarian cancer.
Seiji Mabuchi; Hiromasa Kuroda; Ryoko Takahashi; Tomoyuki Sasano
Gynecologic oncology, Apr. 2015 - Prognostic significance of systemic neutrophil and leukocyte alterations in surgically treated endometrial cancer patients: a monoinstitutional study.
Ryoko Takahashi; Seiji Mabuchi; Mahiru Kawano; Tomoyuki Sasano; Yuri Matsumoto; Hiromasa Kuroda; Takeshi Hisamatsu; Katsumi Kozasa; Kenjiro Sawada; Toshimitsu Hamasaki; Tadashi Kimura
Gynecologic oncology, Apr. 2015 - [Treatment of ovarian clear cell carcinoma].
Seiji Mabuchi; Ryoko Takahashi; Tomoyuki Sasano; Hiromasa Kuroda; Tadashi Kimura
Gan to kagaku ryoho. Cancer & chemotherapy, Feb. 2015 - First two cases of primary carcinoma of the vagina successfully treated with concurrent weekly carboplatin plus paclitaxel, external beam radiotherapy and high-dose-rate interstitial brachytherapy: a case report and published work review.
Seiji Mabuchi; Mahiru Kawano; Fumiaki Isohashi; Hiromasa Kuroda; Tomoyuki Sasano; Tadashi Kimura
The journal of obstetrics and gynaecology research, Jan. 2015 - Uterine cervical cancer displaying tumor-related leukocytosis: a distinct clinical entity with radioresistant feature.
Seiji Mabuchi; Yuri Matsumoto; Mahiru Kawano; Kazumasa Minami; Yuji Seo; Tomoyuki Sasano; Ryoko Takahashi; Hiromasa Kuroda; Takeshi Hisamatsu; Aiko Kakigano; Masami Hayashi; Kenjiro Sawada; Toshimitsu Hamasaki; Eiichi Morii; Hirohisa Kurachi; Nariaki Matsuura; Tadashi Kimura
Journal of the National Cancer Institute, Jul. 2014 - Combination treatment with trabectedin and irinotecan or topotecan has synergistic effects against ovarian clear cell carcinoma cells.
Mahiru Kawano; Seiji Mabuchi; Toshiko Kishimoto; Takeshi Hisamatsu; Yuri Matsumoto; Tomoyuki Sasano; Ryoko Takahashi; Kenjiro Sawada; Kazuhiro Takahashi; Toshifumi Takahashi; Toshimitsu Hamasaki; Tadashi Kimura
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Jun. 2014 - [IV. Targeted therapies for epithelial ovarian cancer].
Seiji Mabuchi; Tomoyuki Sasano; Mahiru Kawano; Tadashi Kimura
Gan to kagaku ryoho. Cancer & chemotherapy, Feb. 2014 - Reirradiation using high-dose-rate interstitial brachytherapy for locally recurrent cervical cancer: a single institutional experience.
Seiji Mabuchi; Ryoko Takahashi; Fumiaki Isohashi; Takeshi Yokoi; Mika Okazawa; Tomoyuki Sasano; Shintaroh Maruoka; Makoto Anzai; Yasuo Yoshioka; Kazuhiko Ogawa; Tadashi Kimura
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Jan. 2014 - Utility of serum squamous cell carcinoma antigen levels at the time of recurrent cervical cancer diagnosis in determining the optimal treatment choice.
Kotaro Shimura; Seiji Mabuchi; Takeshi Yokoi; Tomoyuki Sasano; Kenjirou Sawada; Toshimitsu Hamasaki; Tadashi Kimura
Journal of gynecologic oncology, Oct. 2013 - Potential role of mTORC2 as a therapeutic target in clear cell carcinoma of the ovary.
Takeshi Hisamatsu; Seiji Mabuchi; Yuri Matsumoto; Mahiru Kawano; Tomoyuki Sasano; Ryoko Takahashi; Kenjiro Sawada; Kimihiko Ito; Hirohisa Kurachi; Russell J Schilder; Joseph R Testa; Tadashi Kimura
Molecular cancer therapeutics, Jul. 2013 - Impact of the addition of concurrent chemotherapy to pelvic radiotherapy in surgically treated stage IB1-IIB cervical cancer patients with intermediate-risk or high-risk factors: a 13-year experience.
Mika Okazawa; Seiji Mabuchi; Fumiaki Isohashi; Osamu Suzuki; Yasuo Yoshioka; Tomoyuki Sasano; Yukinobu Ohta; Shoji Kamiura; Kazuhiko Ogawa; Tadashi Kimura
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Mar. 2013
