Last Updated :2025/08/16
Researcher Information
Research activity information
Paper
- Comparison of the effects of renal denervation at early or advanced stages of hypertension on cardiac, renal, and adipose tissue pathology in Dahl salt-sensitive rats.
Kohzo Nagata; Kaito Tagami; Touko Okuzawa; Misaki Hayakawa; Akane Nomura; Tomo Nishimura; Katsuhide Ikeda; Kento Kitada; Shuhei Kobuchi; Yoshihide Fujisawa; Akira Nishiyama; Toyoaki Murohara
Hypertension research : official journal of the Japanese Society of Hypertension, Oct. 2024, [Reviewed] - Vascular Endothelial Dysfunction in the Thoracic Aorta of Rats with Ischemic Acute Kidney Injury: Contribution of Indoxyl Sulfate.
Keisuke Nakagawa; Ryosuke Tanaka; Masahide Donouchi; Masaya Kanda; Saaya Kamada; Shuhei Kobuchi; Masashi Tawa; Yasuo Matsumura; Mamoru Ohkita
Oxidative medicine and cellular longevity, 2022, [Reviewed] - Renal sympathetic nerve activity regulates cardiovascular energy expenditure in rats fed high salt.
Norihiko Morisawa; Kento Kitada; Yoshihide Fujisawa; Daisuke Nakano; Daisuke Yamazaki; Shuhei Kobuchi; Lei Li; Yifan Zhang; Takashi Morikawa; Yoshio Konishi; Takashi Yokoo; Friedrich C Luft; Jens Titze; Akira Nishiyama
Hypertension research : official journal of the Japanese Society of Hypertension, Jun. 2020, [Reviewed] - Neutrophil/lymphocyte ratio elevation in renal dysfunction is caused by distortion of leukocyte hematopoiesis in bone marrow.
Ito Satoyasu; Ohno Yoshiya; Tanaka Toshiyuki; Kobuchi Shuhei; Ayajiki Kazuhide; Manabe Eri; Masuyama Tohru; Jun-Ichi Sakamoto; Tsujino Takeshi
Renal failure, Nov. 2019, [Reviewed] - Mechanisms underlying the renoprotective effect of GABA against ischaemia/reperfusion-induced renal injury in rats
Shuhei Kobuchi; Ryosuke Tanaka; Takuya Shintani; Rie Suzuki; Hidenobu Tsutsui; Mamoru Ohkita; Yasuo Matsumura; Kazuhide Ayajiki
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, Mar. 2015, [Reviewed]
Lead - Nitric oxide modulation of endothelium-derived hyperpolarizing factor in agonist-induced depressor responses in anesthetized rats.
Kobuchi S; Miura K; Iwao H; Ayajiki K
Eur J Pharmacol, 2015, [Reviewed]
Lead - Involvement of Renal Sympathetic Nerve Overactivation in the Progression of Chronic Kidney Disease in Rats
Shuhei Kobuchi; Ryosuke Tanaka; Asami Funai; Rie Suzuki; Maki Yazawa; Hidenobu Tsutsui; Mamoru Ohkita; Kazuhide Ayajiki; Yasuo Matsumura
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, Jan. 2014, [Reviewed]
Lead - Beneficial effects of γ-aminobutyric acid on right ventricular pressure and pulmonary vascular remodeling in experimental pulmonary hypertension.
Suzuki R; Maehara R; Kobuchi S; Tanaka R; Ohkita M; Matsumura Y
Life sciences, Oct. 2012, [Reviewed] - Protective effect of 17β-estradiol on ischemic acute kidney injury through the renal sympathetic nervous system.
Tanaka R; Tsutsui H; Kobuchi S; Sugiura T; Yamagata M; Ohkita M; Takaoka M; Yukimura T; Matsumura Y
European journal of pharmacology, May 2012, [Reviewed] - Nitrergic nerves derived from the pterygopalatine ganglion innervate arteries irrigating the cerebrum but not the cerebellum and brain stem in monkeys.
Ayajiki K; Kobuchi S; Tawa M; Okamura T
Hypertens Res, 2012, [Reviewed] - Mechanisms underlying the renoprotective effect of GABA against ischemia/reperfusion-induced renal injury in rats.
Kobuchi S; Tanaka R; Shintani T; Suzuki R; Tsutsui H; Ohkita M; Ayajiki K; Matsumura Y
The Journal of pharmacology and experimental therapeutics, Sep. 2011, [Reviewed]
MISC
- Effects of drinking water administration of indoxyl sulfate, a urea toxin, on vascular endothelial function in normal rats
中川恵輔; 戸田成美; 小渕修平; 田和正志; 大喜多守
日本薬学会年会要旨集(Web), 2023 - Differential effects of early versus late phase renal denervation on hypertension, cardiac, renal, and adipose pathology in Dahl salt-sensitive rats
早川美咲; 野村朱音; 西村知; 古川希; 小渕修平; 中野志保; 芦川采央; 河合夢乃; 崔茜茜; 坂部名奈子; 池田勝秀; 北田研人; 藤澤良秀; 西山成; 永田浩三
日本高血圧学会総会プログラム・抄録集(CD-ROM), 2021 - 虚血性急性腎障害に併発する血管内皮機能障害におけるインドキシル硫酸の関与
中川恵輔; 堂内政秀; 神田将哉; 鎌田沙彩; 小渕修平; 田中亮輔; 田和正志; 松村靖夫; 大喜多守
日本循環薬理学会口演要旨集, 2021 - Effect of antioxidants against vascular dysfunction in adenine-induced renal injury in rats
酒井悠華; 加藤彩綺; 小西莉子; 向圭吾; 小渕修平
日本薬学会年会要旨集(Web), 2020 - Dahl食塩感受性高血圧ラットは,高食塩摂取により異常な腎交感神経活性化が生じ,心血管エネルギー消費量が増大する
森澤紀彦; 北田研人; 藤澤良秀; 中野大介; 山崎大輔; 小渕修平; 西山成
日本高血圧学会総会プログラム・抄録集(CD-ROM), 2019 - Functional impairment of NO is earlier than that of EDHF in 5/6 nephrectomized rat
Shuhei Kobuchi; Kazuhide Ayajiki
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2014 - Modification of acetylcholine-induced depressor response by chronic kidney disease in anesthetized rat
Shuhei Kobuchi; Kazuhide Ayajiki
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013 - Possible role of gap junction agonist-induced endothelium-dependent hypotension in anesthetized rats
Shuhei Kobuchi; Kazuhide Ayajiki
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012 - 虚血性急性腎障害における17β-エストラジオールの腎交感神経系を介した保護効果について
田中亮輔; 筒居秀伸; 杉浦孝宏; 小渕修平; 山形雅代; 大喜多守; 高岡昌徳; 雪村時人; 松村靖夫
血管, 2011 - Gender difference of ischemia/reperfusion-induced acute kidney injury is dependent on renal sympathetic nervous system
Hidenobu Tsutsui; Ryosuke Tanaka; Toshihide Fujii; Shuhei Kobuchi; Takao Tanba; Yui Bonkohara; Masayo Yamagata; Mamoru Ohkita; Masanori Takaoka; Yasuo Matsumura; Tokihito Yukimura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011 - Mechanisms underlying agonist-induced endothelium-dependent hypotension in anesthetized rats
Shuhei Kobuchi; Kazuhide Ayajiki
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011 - gamma-Aminobutyric acid attenuates monocrotaline-induced pulmonary hypertension in rats by suppressing plasma norepinephrine level
Rie Suzuki; Rumi Maehara; Shuhei Kobuchi; Mamoru Ohkita; Yasuo Matsumura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011 - Protective effect of 17 beta-estradiol on ischemic acute kidney injury through renal sympathetic nervous system
Ryosuke Tanaka; Hidenobu Tsutsui; Takahiro Sugiura; Shuhei Kobuchi; Asami Funai; Masayo Yamagata; Mamoru Ohkita; Masanori Takaoka; Tokihito Yukimura; Yasuo Matsumura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011 - ラット腎虚血再灌流障害に対する内因性モノアミンオキシダーゼ阻害物質イサチンの効果
三浦健; 三浦健; 筒居秀伸; 筒居秀伸; 小渕修平; 田中亮輔; 山形雅代; 大喜多守; 松村靖夫; 雪村時人; 寺田知行
日本薬学会年会要旨集, 2010 - Effects of gamma-aminobutyric acid on monocrotaline-induced pulmonary hypertension in rats
Rie Suzuki; Shuhei Kobuchi; Mamoru Ohkita; Yasuo Matsumura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010 - Sympathetic role in 5/6 nephrectomized-induced chronic kidney disease in rats
Shuhei Kobuchi; Ryosuke Tanaka; Rie Suzuki; Hidenobu Tsutsui; Mamoru Ohkita; Kazuhide Ayajiki; Yasuo Matsumura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010 - The effect of monoamine oxidase inhibitor on ischemia/reperfusion-induced acute kidney injury in rats
Hidenobu Tsutsui; Takeshi Miura; Shuhei Kobuchi; Ryosuke Tanaka; Masayo Yamagata; Mamoru Ohkita; Yasuo Matsumura; Tokihito Yukimura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010 - Renoprotective effects of gamma-aminobutyric acid on ischemia/reperfusion-induced renal injury in rats
Shuhei Kobuchi; Takuya Shintani; Takahiro Sugiura; Ryosuke Tanaka; Rie Suzuki; Hidenobu Tsutsui; Toshihide Fujii; Mamoru Ohkita; Kazuhide Ayajiki; Yasu Matsumura
EUROPEAN JOURNAL OF PHARMACOLOGY, Nov. 2009 - Antihypertensive effect of French maritime pine bark extract (Flavangenol): possible involvement of endothelial nitric oxide-dependent vasorelaxation
Chol-Jun Kwak; Eriko Kubo; Kiwako Fujii; Yuri Nishimura; Shuhei Kobuchi; Mamoru Ohkita; Makiko Yoshimura; Yoshinobu Kiso; Yasuo Matsumura
JOURNAL OF HYPERTENSION, Jan. 2009 - Preventive mechanisms of agmatine against ischemic acute kidney injury in rats
Takahiro Sugiura; Shuhei Kobuchi; Hidenobu Tsutsui; Masanori Takaoka; Toshihide Fujii; Kentaro Hayashi; Yasuo Matsumura
EUROPEAN JOURNAL OF PHARMACOLOGY, Jan. 2009 - Preventive mechanism of gamma-aminobutyric acid on ischemic/reperfusion-induced renal injury in rats
Shuhei Kobuchi; Ryosuke Tanaka; Takuya Shintani; Rie Suzuki; Takahiro Sugiura; Hidenobu Tsutsui; Toshihide Fujii; Mamoru Ohkita; Yasuo Matsumura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009 - Gender difference of ischemia/reperfusion-induced acute kidney injury is independent of endothelial nitric oxide synthase
Naoki Zenda; Mamoru Ohkita; Hidenobu Tsutsui; Shuhei Kobuchi; Hiroko Tamaki; Ryosuke Tanaka; Rie Suzuki; Yasuo Matsumura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009 - Protective effect of agmatine on ischemia/reperfusion-induced renal injury in rats
Takahiro Sugiura; Hidenobu Tsutsui; Masanori Takaoka; Shuhei Kobuchi; Kentaro Hayashi; Toshihide Fujii; Yasuo Matsumura
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, Mar. 2008 - Protective effect of 17 beta-estradiol on ischemic acute renal failure through the PI3K/Akt/eNOS pathway
A. Satake; M. Takaoka; M. Nishikawa; M. Yuba; Y. Shibata; K. Okumura; K. Kitano; H. Tsutsui; K. Fujii; S. Kobuchi; M. Ohkita; Y. Matsumura
KIDNEY INTERNATIONAL, Feb. 2008 - Selective antagonism of the postsynaptic alpha(1)-adrenoceptor is protective against ischemic acute renal failure in rats
Toshihide Fujii; Takahiro Sugiura; Mamoru Ohkita; Shuhei Kobuchi; Masanori Takaoka; Yasuo Matsumura
EUROPEAN JOURNAL OF PHARMACOLOGY, Nov. 2007 - Preventive mechanisms of agmatine against ischemic acute renal failure in rats
Takabiro Sugiura; Masanori Takaoka; Shuhei Kobuchi; Hidenobu Tsutsui; Toshihide Fujii; Kentaro Hayashi; Yasuo Matsumura
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2007
