Last Updated :2024/09/11
Researcher Information
Career
- Apr. 2016 - Present
Hyogo College of Medicine, 免疫学教室, 講師 - May 2017 - Apr. 2019
Stanford University School of Medicine, Department of Pathology, Visiting Assisitant Professor - Dec. 2014 - Mar. 2016
Hyogo College of Medicine, Institute for Advanced Medical Sciences, 講師 - Apr. 2010 - Nov. 2014
Hyogo College of Medicine, Institute for Advanced Medical Sciences, 助教 - Apr. 2009 - Mar. 2010
Osaka University, Research Institute for Microbial Diseases, 特任研究員
Research activity information
Paper
- Dynamin-related protein 1 differentially regulates FcεRI- and substance P-induced mast cell activation
Ying Wang; Mang Yu; Kazufumi Matsushita; Chen Liu; Naotada Ishihara; Masatoshi Nomura; Mindy Tsai; Stephen J. Galli
Journal of Allergy and Clinical Immunology, Nov. 2022 - The role of Sp140 revealed in IgE and mast cell responses in Collaborative Cross mice
Kazufumi Matsushita; Xin Li; Yuki Nakamura; Danyue Dong; Kaori Mukai; Mindy Tsai; Stephen B. Montgomery; Stephen J. Galli
JCI Insight, Jun. 2021 - Thymic stromal lymphopoietin contributes to protection of mice from Strongyloides venezuelensis infection by CD4+ T cell-dependent and -independent pathways.
Atsuhide Koida; Koubun Yasuda; Takumi Adachi; Kazufumi Matsushita; Makoto Yasuda; Shigeru Hirano; Etsushi Kuroda
Biochemical and biophysical research communications, May 2021 - Transcriptome programming of IL‐3‐dependent bone marrow‐derived cultured mast cells by stem cell factor (SCF)
Ying Wang; Kazufumi Matsushita; Jennifer Jackson; Takafumi Numata; Yue Zhang; Gao Zhou; Mindy Tsai; Stephen J. Galli
Allergy, Mar. 2021 - Regnase-1 degradation is crucial for IL-33- and IL-25-mediated ILC2 activation.
Kazufumi Matsushita; Hiroki Tanaka; Koubun Yasuda; Takumi Adachi; Ayumi Fukuoka; Shoko Akasaki; Atsuhide Koida; Etsushi Kuroda; Shizuo Akira; Tomohiro Yoshimoto
JCI insight, Feb. 2020 - Human cystatin SN is an endogenous protease inhibitor that prevents allergic rhinitis.
Fukuoka A; Matsushita K; Morikawa T; Adachi T; Yasuda K; Kiyonari H; Fujieda S; Yoshimoto T
The Journal of allergy and clinical immunology, Mar. 2019, [Reviewed] - Interleukin-1/-33 Signaling Pathways as Therapeutic Targets for Endometriosis.
Kato T; Yasuda K; Matsushita K; Ishii KJ; Hirota S; Yoshimoto T; Shibahara H
Frontiers in immunology, 2019, [Reviewed] - Activation of group 2 innate lymphoid cells exacerbates and confers corticosteroid resistance to mouse nasal type 2 inflammation
Taiyo Morikawa; Ayumi Fukuoka; Kazufumi Matsushita; Koubun Yasuda; Naruhito Iwasaki; Shoko Akasaki; Shigeharu Fujieda; Tomohiro Yoshimoto
INTERNATIONAL IMMUNOLOGY, May 2017, [Reviewed] - Allergen endotoxins induce T-cell-dependent and non-IgE-mediated nasal hypersensitivity in mice
Naruhito Iwasaki; Kazufumi Matsushita; Ayumi Fukuoka; Masakiyo Nakahira; Makoto Matsumoto; Shoko Akasaki; Koubun Yasuda; Takeshi Shimizu; Tomohiro Yoshimoto
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Jan. 2017, [Reviewed] - Murine allergic rhinitis and nasal T-h2 activation are mediated via TSLP- and IL-33-signaling pathways
Shoko Akasaki; Kazufumi Matsushita; Yukinori Kato; Ayumi Fukuoka; Naruhito Iwasaki; Masakiyo Nakahira; Shigeharu Fujieda; Koubun Yasuda; Tomohiro Yoshimoto
INTERNATIONAL IMMUNOLOGY, Feb. 2016, [Reviewed] - Essential Function for the Nuclear Protein Akirin2 in B Cell Activation and Humoral Immune Responses
Sarang Tartey; Kazufumi Matsushita; Tomoko Imamura; Atsuko Wakabayashi; Daisuke Ori; Takashi Mino; Osamu Takeuchi
JOURNAL OF IMMUNOLOGY, Jul. 2015, [Reviewed] - Proallergic cytokines and group 2 innate lymphoid cells in allergic nasal diseases
Kazufumi Matsushita; Yukinori Kato; Shoko Akasaki; Tomohiro Yoshimoto
ALLERGOLOGY INTERNATIONAL, Jul. 2015, [Reviewed] - B Cell-Intrinsic MyD88 Signaling Is Essential for IgE Responses in Lungs Exposed to Pollen Allergens
Kazufumi Matsushita; Tomohiro Yoshimoto
JOURNAL OF IMMUNOLOGY, Dec. 2014, [Reviewed] - Hypertrophy of lymphoid organs is a possible phenotypic characteristic of R420W mutation of the cardiac ryanodine receptor gene: A study using a knock-in mouse model
Hajime Nishio; Noriyuki Okudaira; Kazufumi Matsushita; Tomohiro Yoshimoto; Takako Sato; Koichi Suzuki
LEGAL MEDICINE, Nov. 2014, [Reviewed] - Akirin2 is critical for inducing inflammatory genes by bridging I kappa B-zeta and the SWI/SNF complex
Sarang Tartey; Kazufumi Matsushita; Alexis Vandenbon; Daisuke Ori; Tomoko Imamura; Takashi Mino; Daron M. Standley; Jules A. Hoffmann; Jean-Marc Reichhart; Shizuo Akira; Osamu Takeuchi
EMBO JOURNAL, Oct. 2014, [Reviewed] - The role of basophils and proallergic cytokines, TSLP and IL-33, in cutaneously sensitized food allergy
Taichiro Muto; Ayumi Fukuoka; Kenji Kabashima; Steven F. Ziegler; Kenji Nakanishi; Kazufumi Matsushita; Tomohiro Yoshimoto
INTERNATIONAL IMMUNOLOGY, Oct. 2014, [Reviewed] - Nasal Sensitization with Ragweed Pollen Induces Local-Allergic-Rhinitis-Like Symptoms in Mice
Yukinori Kato; Shoko Akasaki; Yoko Muto-Haenuki; Shigeharu Fujieda; Kazufumi Matsushita; Tomohiro Yoshimoto
PLOS ONE, Aug. 2014, [Reviewed] - Innate-Type and Acquired-Type Allergy Regulated by IL-33
Tomohiro Yoshimoto; Kazufumi Matsushita
ALLERGOLOGY INTERNATIONAL, May 2014, [Reviewed] - Pathogenic T(h)2-type follicular helper T cells contribute to the development of lupus in Fas-deficient mice
Shizue Futatsugi-Yumikura; Kazufumi Matsushita; Ayumi Fukuoka; Suzuka Takahashi; Nayu Yamamoto; Shin Yonehara; Kenji Nakanishi; Tomohiro Yoshimoto
INTERNATIONAL IMMUNOLOGY, Apr. 2014, [Reviewed] - Interleukin-33: A multifunctional alarmin that promotes both health and disease.
Matsushita K; Yoshimoto T
Cytokine Frontiers: Regulation of Immune Responses in Health and Disease,, 2014, [Invited] - Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation.
Takuya Uehata; Hidenori Iwasaki; Alexis Vandenbon; Kazufumi Matsushita; Eduardo Hernandez-Cuellar; Kanako Kuniyoshi; Takashi Satoh; Takashi Mino; Yutaka Suzuki; Daron M Standley; Tohru Tsujimura; Hiromi Rakugi; Yoshitaka Isaka; Osamu Takeuchi; Shizuo Akira
Cell, May 2013, [Reviewed] - A critical role of IL-33 in experimental allergic rhinitis
Yoko Haenuki; Kazufumi Matsushita; Shizue Futatsugi-Yumikura; Ken J. Ishii; Tatsukata Kawagoe; Yoshimasa Imoto; Shigeharu Fujieda; Makoto Yasuda; Yasuo Hisa; Shizuo Akira; Kenji Nakanishi; Tomohiro Yoshimoto
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Jul. 2012, [Reviewed] - Contribution of IL-33-activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice
Koubun Yasuda; Taichiro Muto; Tatsukata Kawagoe; Makoto Matsumoto; Yuki Sasaki; Kazufumi Matsushita; Yuko Taki; Shizue Futatsugi-Yumikura; Hiroko Tsutsui; Ken J. Ishii; Tomohiro Yoshimoto; Shizuo Akira; Kenji Nakanishi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Feb. 2012, [Reviewed] - The I kappa B kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1
Hidenori Iwasaki; Osamu Takeuchi; Shunsuke Teraguchi; Kazufumi Matsushita; Takuya Uehata; Kanako Kuniyoshi; Takashi Satoh; Tatsuya Saitoh; Mutsuyoshi Matsushita; Daron M. Standley; Shizuo Akira
NATURE IMMUNOLOGY, Dec. 2011, [Reviewed] - Negative regulators in toll-like receptor responses
Shizuo Akira; Tatsuya Saitoh; Kazufumi Matsushita; Osamu Takeuchi
Cornea, Nov. 2010, [Reviewed] - The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
Takashi Satoh; Osamu Takeuchi; Alexis Vandenbon; Koubun Yasuda; Yoshiaki Tanaka; Yutaro Kumagai; Tohru Miyake; Kazufumi Matsushita; Toshihiko Okazaki; Tatsuya Saitoh; Kiri Honma; Toshifumi Matsuyama; Katsuyuki Yui; Tohru Tsujimura; Daron M. Standley; Kenji Nakanishi; Kenta Nakai; Shizuo Akira
NATURE IMMUNOLOGY, Oct. 2010, [Reviewed] - I kappa B zeta is essential for natural killer cell activation in response to IL-12 and IL-18
Tohru Miyake; Takashi Satoh; Hiroki Kato; Kazufumi Matsushita; Yutaro Kumagai; Alexis Vandenbon; Tohru Tani; Tatsushi Muta; Shizuo Akira; Osamu Takeuchi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Oct. 2010, [Reviewed] - LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses
Takashi Satoh; Hiroki Kato; Yutaro Kumagai; Mitsutoshi Yoneyama; Shintaro Sato; Kazufumi Matsushita; Tohru Tsujimura; Takashi Fujita; Shizuo Akira; Osamu Takeuchi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jan. 2010, [Reviewed] - [Control of inflammatory responses by a novel RNase, Zc3h12a].
Takeuchi O; Matsushita K; Akira S
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Nov. 2009, [Reviewed] - Poly I:C-Induced Activation of NK Cells by CD8 alpha(+) Dendritic Cells via the IPS-1 and TRIF-Dependent Pathways
Tohru Miyake; Yutaro Kumagai; Hiroki Kato; Zijin Guo; Kazufumi Matsushita; Takashi Satoh; Tatsukata Kawagoe; Himanshu Kumar; Myoung Ho Jang; Taro Kawai; Tohru Tani; Osamu Takeuchi; Shizuo Akira
JOURNAL OF IMMUNOLOGY, Aug. 2009, [Reviewed] - Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay
Kazufumi Matsushita; Osamu Takeuchi; Daron M. Standley; Yutaro Kumagai; Tatsukata Kawagoe; Tohru Miyake; Takashi Satoh; Hiroki Kato; Tohru Tsujimura; Haruki Nakamura; Shizuo Akira
NATURE, Apr. 2009, [Reviewed] - Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5
Hiroki Kato; Osamu Takeuchi; Eriko Mikamo-Satoh; Reiko Hirai; Tomoji Kawai; Kazufumi Matsushita; Akane Hiiragi; Terence S. Dermody; Takashi Fujita; Shizuo Akira
JOURNAL OF EXPERIMENTAL MEDICINE, Jul. 2008, [Reviewed] - Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2
Tatsukata Kawagoe; Shintaro Sato; Kazufumi Matsushita; Hiroki Kato; Kosuke Matsui; Yutaro Kumagai; Tatsuya Saitoh; Taro Kawai; Osamu Takeuchi; Shizuo Akira
NATURE IMMUNOLOGY, Jun. 2008, [Reviewed] - Erratum: Akirins are highly conserved nuclear proteins required for NF-κB-dependent gene expression in drosophila and mice (Nature Immunology (2008) vol. 9 (97-104)
Akira Goto; Kazufumi Matsushita; Viola Gesellchen; Laure El Chamy; David Kuttenkeuler; Osamu Takeuchi; Jules A. Hoffmann; Shizuo Akira; Michael Boutros; Jean Marc Reichhart
Nature Immunology, Feb. 2008, [Reviewed] - Akirins are highly conserved nuclear proteins required for NF-kappa B-dependent gene expression in drosophila and mice
Akira Goto; Kazufumi Matsushita; Viola Gesellchen; Laure El Chamy; David Kuttenkeuler; Osamu Takeuchi; Jules A. Hoffmann; Shizuo Akira; Michael Boutros; Jean-Marc Reichhart
NATURE IMMUNOLOGY, Jan. 2008, [Reviewed]
MISC
- 【慢性副鼻腔炎up-to-date】エンドトキシンによりひき起こされるI型過敏症様鼻炎反応
松下 一史
臨床免疫・アレルギー科, Apr. 2019 - ILC2-activation exacerbates nasal type 2 inflammation in mice
Taiyo Morikawa; Ayumi Fukuoka; Kazufumi Matsushita; Shigeharu Fujieda; Tomohiro Yoshimoto
CYTOKINE, Dec. 2017 - アレルギー性鼻炎 ここまで解った病態 治療への展望 エンドトキシンを引き金としたIgE非依存性鼻炎症状の誘導
岩崎 成仁; 松下 一史; 清水 猛史; 善本 知広
アレルギー, May 2016 - ケミカルメディエーター/サイトカイン・ケモカイン アレルギー性鼻炎モデルマウスにおけるTSLPの役割
赤崎 晶子; 加藤 幸宣; 松下 一史; 善本 知広
アレルギー, Apr. 2015 - 気道炎症の病態と自然免疫 気道への花粉曝露によるIL-1ファミリーサイトカインを介した抗原特異的IgEの誘導
松下 一史; 善本 知広
アレルギー, Apr. 2015 - 【IL-33】IL-33による感染症防御
松下 一史; 善本 知広
医学のあゆみ, Mar. 2015 - Essential Role of B-Cell-Intrinsic MyD88-Signaling in IgE Responses in Lungs
Kazufumi Matsushita; Tomohiro Yoshimoto
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Feb. 2015 - The Role of Basophils and Pro-Allergic Cytokines, TSLP and IL-33, in Cutaneously-Sensitized Food Allergy
Taichiro Muto; Ayumi Fukuoka; Kazufumi Matsushita; Tomohiro Yoshimoto
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Feb. 2015 - Diesel Exhaust Particles Exacerbate Allergic Rhinitis in Mice By Disrupting the Nasal Epithelial Barrier
Ayumi Fukuoka; Kazufumi Matsushita; Hirohisa Takano; Tomohiro Yoshimoto
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Feb. 2015 - 【病態の理解に向かう アレルギー疾患研究-なぜ、アレルギーが起こるのか?発症・進展の新概念と臨床への展開】(第2章)アレルギーを制御する免疫細胞・基盤分子の最新トピック 顆粒球のアレルギー疾患における新たな役割
松下 一史; 善本 知広
実験医学, Nov. 2013 - 【サイトカインと疾患 あらたな病態モデルから治療へ】サイトカインの分泌刺激および産生調節機構 mRNAの安定性制御を介した免疫応答の調節
松下 一史; 審良 静男
医学のあゆみ, Jul. 2010 - 自然免疫と自己免疫疾患
松下 一史; 竹内 理; 審良 静男
炎症と免疫, Dec. 2009 - 【シグナル伝達病を知る その分子機序解明から新たな治療戦略まで】基礎編 免疫系のシグナル伝達 TLRを介したシグナル伝達
松下 一史; 審良 静男
遺伝子医学MOOK, Dec. 2006
