Last Updated :2026/08/21
Research activity information
Paper
- β-Hydroxybutyrate Attenuates Cardiac Inflammation and Hepatic Fibrosis in Dahl Salt-Sensitive Rats
Satoyasu Ito; Eri Manabe; Toshiyuki Shikata; Kojiro Takamoto; Shuhei Kobuchi
Current Issues in Molecular Biology, Jun. 2026 - Dimethyl Fumarate Ameliorated Cardiorenal Anemia Syndrome and Improved Overall Survival in Dahl/Salt-Sensitive Rats.
Satoyasu Ito; Fuyuka Yamatani; Yuri Arai; Eri Manabe; Takeshi Tsujino
The Journal of pharmacology and experimental therapeutics, Dec. 2023 - Juzentaihoto improves adenine-induced chronic renal failure in BALB/c mice via suppression of renal fibrosis and inflammation.
Satoyasu Ito; Eri Manabe; Yi Dai; Masaharu Ishihara; Takeshi Tsujino
Journal of pharmacological sciences, Jan. 2022 - Low Quality of Warfarin Therapy is Associated With Female Gender but Not With Polypharmacy in Patients With Atrial Fibrillation.
Kojiro Takamoto; Jun-Ichi Sakamoto; Satoyasu Ito; Takeshi Kimura; Eri Manabe; Toshiyuki Shikata; Masanori Asakura; Masaharu Ishihara; Takeshi Tsujino
Frontiers in pharmacology, 2021 - Reduced lifespan of erythrocytes in Dahl/Salt sensitive rats is the cause of the renal proximal tubule damage.
Eri Manabe; Satoyasu Ito; Yoshiya Ohno; Toshiyuki Tanaka; Yoshiro Naito; Naoko Sasaki; Masanori Asakura; Tohru Masuyama; Masaharu Ishihara; Takeshi Tsujino
Scientific reports, Dec. 2020 - Polypharmacy Is Associated With Accelerated Deterioration of Renal Function in Cardiovascular Outpatients.
Jun-Ichi Sakamoto; Toshiyuki Shikata; Satoyasu Ito; Takeshi Kimura; Kojiro Takamoto; Eri Manabe; Masanori Asakura; Masaharu Ishihara; Takeshi Tsujino
Cardiology research, Feb. 2020 - Neutrophil/lymphocyte ratio elevation in renal dysfunction is caused by distortion of leukocyte hematopoiesis in bone marrow.
Satoyasu Ito; Yoshiya Ohno; Toshiyuki Tanaka; Shuhei Kobuchi; Kazuhide Ayajiki; Eri Manabe; Tohru Masuyama; Sakamoto Jun-Ichi; Takeshi Tsujino
Renal failure, Nov. 2019 - Olmesartan inhibits cultured rat aortic smooth muscle cell death induced by cyclic mechanical stretch through the inhibition of the c-Jun N-terminal kinase and p38 signaling pathways.
Satoyasu Ito; Kentaro Ozawa; Jing Zhao; Yoji Kyotani; Kosuke Nagayama; Masanori Yoshizumi
Journal of pharmacological sciences, Jan. 2015 - Exendin-4 Prevents Vascular Smooth Muscle Cell Proliferation and Migration by Angiotensin II via the Inhibition of ERK1/2 and JNK Signaling Pathways.
Kosuke Nagayama; Yoji Kyotani; Jing Zhao; Satoyasu Ito; Kentaro Ozawa; Francesco A Bolstad; Masanori Yoshizumi
PloS one, 2015 - Azelnidipine inhibits cultured rat aortic smooth muscle cell death induced by cyclic mechanical stretch.
Jing Zhao; Kentaro Ozawa; Yoji Kyotani; Kosuke Nagayama; Satoyasu Ito; Akira T Komatsubara; Yuichi Tsuji; Masanori Yoshizumi
PloS one, 2014 - Intermittent hypoxia induces the proliferation of rat vascular smooth muscle cell with the increases in epidermal growth factor family and erbB2 receptor.
Yoji Kyotani; Hiroyo Ota; Asako Itaya-Hironaka; Akiyo Yamauchi; Sumiyo Sakuramoto-Tsuchida; Jing Zhao; Kentaro Ozawa; Kosuke Nagayama; Satoyasu Ito; Shin Takasawa; Hiroshi Kimura; Masayuki Uno; Masanori Yoshizumi
Experimental cell research, Nov. 2013 - COMPARISON OF THE EFFECTS OF SRC INHIBITION AND MITOGEN-ACTIVATED PROTEIN KINASE INHIBITION ON THE MIGRATION OF VASCULAR SMOOTH MUSCLE CELLS STIMULATED BY ANGIOTENSIN II
ZHAO Jing; 京谷陽司; 伊藤都裕; 長山功佑; 小澤健太郎; 吉栖正典
Journal of Nara Medical Association, Apr. 2012 - Obstructive Sleep Apnea and Cardiovascular Diseases
Kyotani Yoji; Zhao Jing; Nagayama Kosuke; Ito Satoyasu; Ozawa Kentaro; Yoshizumi Masanori
Japanese Journal of Circulation Research, 2012, [Reviewed] - Role of big mitogen-activated protein kinase 1 (BMK1) / extracellular signal-regulated kinase 5 (ERK5) in the pathogenesis and progression of atherosclerosis.
Masanori Yoshizumi; Yoji Kyotani; Jing Zhao; Kosuke Nagayama; Satoyasu Ito; Yuichi Tsuji; Kentaro Ozawa
Journal of pharmacological sciences, 2012 - Big mitogen-activated protein kinase 1 protects cultured rat aortic smooth muscle cells from oxidative damage.
Jing Zhao; Yoji Kyotani; Satoyasu Itoh; Hitoshi Nakayama; Minoru Isosaki; Masanori Yoshizumi
Journal of pharmacological sciences, 2011
MISC
- The effect of SGLT2 inhibitors on liver fibrosis in hypertensive patients with type 2 diabetes mellitus
吉平凪沙; 伊藤都裕; 岡山眞理; 竹内陽平; 鳥井愛; 三浦笑華; 内藤由朗; 石原正治; 辻野健; 辻野健
日本薬学会年会, 2025 - Effect of sodium-glucose transporter-2 inhibitor on visit-to-visit blood pressure variation
竹内陽平; 伊藤都裕; 鳥井愛; 三浦笑華; 吉平凪沙; 岡山眞理; 内藤由朗; 石原正治; 辻野健; 辻野健
日本薬学会年会, 2025 - High FIB-4 index, non-invasive marker of liver fibrosis, is associated with atrial fibrillation in hypertensive patients with type 2 diabetes mellitus
岡山眞理; 伊藤都裕; 竹内陽平; 鳥井愛; 三浦笑華; 吉平凪沙; 内藤由朗; 石原正治; 辻野健; 辻野健
日本薬学会年会, 2025 - Blood pressure lowering effect of sodium-glucose transporter-2 inhibitor is associated with renal function
三浦笑華; 伊藤都裕; 吉平凪沙; 岡山眞理; 竹内陽平; 鳥井愛; 内藤由朗; 石原正治; 辻野健; 辻野健
日本薬学会年会, 2025 - Red bood cell distribution width-CV predicts increase in hemoglobin by sodium-glucose transporter-2 inhibitors
鳥井愛; 伊藤都裕; 三浦笑華; 吉平凪沙; 岡山眞理; 竹内陽平; 内藤由朗; 石原正治; 辻野健; 辻野健
日本薬学会年会, 2025 - FIB-4 index, an indicator of liver fibrosis, is associated with left atrial enlargement in hypertensive patients with type 2 diabetes mellitus
北村優太; 伊藤都裕; KIM Hyocheon; 内橋未希; 打越里奈; 岡田優美花; 富田月子; 内藤由朗; 朝倉正紀; 石原正治; 辻野健; 辻野健
日本薬学会年会, 2024 - SGLT2 inhibitors improve FIB-4 index, a marker of liver fibrosis, in hypertensive patients with type2 diabetes mellitus
内橋未希; 伊藤都裕; 打越里奈; 岡田優美花; 北村優太; KIM Hyocheon; 富田月子; 内藤由朗; 朝倉正紀; 石原正治; 辻野健; 辻野健
日本薬学会年会, 2024 - Use of hypnotics and anxiolytics is associated with increase in left ventricular mass in hypertensive patients with type 2 diabetes mellitus.
KIM Hyocheon; 伊藤都裕; 内橋未希; 打越里奈; 岡田優美花; 北村優太; 富田月子; 内藤由朗; 朝倉正紀; 石原正治; 辻野健; 辻野健
日本薬学会年会, 2024 - Liver Fibrosis Index Predicts Left Atrial Enlargement in Hypertensive Patients with Tye 2 Diabetes Mellitus
辻野健; 伊藤都裕; 内藤由朗; 朝倉正紀; 石原正治
日本高血圧学会総会, 2024 - Sodium-glucose Transporter-2 Inhibitor Lowered Left Atrial Pressure in Hypertensive Patients with Diabetes Mellitus
辻野健; 伊藤都裕; 内藤由朗; 朝倉正紀; 石原正治
日本高血圧学会総会, 2023 - Sodium-glucose transporter-2 inhibitor ameliorated left ventricular hypertrophy and improved diastolic function in hypertensive patients with diabetes mellitus
新井優里; 伊藤都裕; 山谷冬華; 浅川裕介; 森園愛美; 思川佳歩; 垣下未優; 東川美希; 内藤由朗; 朝倉正紀; 石原正治; 辻野健; 辻野健
日本薬学会年会, 2023 - Dimethyl fumarate ameliorated cardiac mRNA expression of TGF-β1 and ICAM-1 and improved survival of salt-loaded Dahl/Salt sensitive rats
山谷冬華; 伊藤都裕; 新井優里; 辻野健
日本薬学会年会, 2023 - Dimethyl fumarate improves rat viability with suppression of blood pressure, TGF-β expression and renal damage in Dahl/Salt sensitive rats.
Satoyasu Ito, Takeshi Tsujino
The 29th Scientific Meeting of the International Society of Hypertension, Oct. 2022 - Increased visit-to-visit blood pressure variability is associated with left atrium enlargement and high RDW-CV in hypertensive patients
Takeshi Tsujino; Satoyasu Ito; Yoshiro Naito; Masanori Asakura; Masaharu Ishihara
The 29th Scientific Meeting of the International Society of Hypertension, Oct. 2022 - Increase in visit-to-visit systolic blood pressure variability is associated with enlargement of left atrium in patients with hypertension
今別府和歌菜; 伊藤都裕; 小澤研一; 片浦里咲; 古賀愛梨; 富田佳歩; 内藤あすか; 松本遥; 内藤由朗; 朝倉正紀; 石原正治; 辻野健; 辻野健
日本薬学会年会, 2022 - Increase in visit-to-visit systolic blood pressure variability is associated with enlargement of left atrium in patients with hypertension
辻野健; 辻野健; 伊藤都裕; 内藤由朗; 朝倉正紀; 石原正治
日本高血圧学会総会, 2021 - Juzen-taiho-to Ameliorates Renal Injury and Neutrophil/Lymphocyte Ratio Elevation in Chronic Renal Failure
伊藤都裕; 辻野健; 真鍋恵理
日本循環器学会学術集会, 2020 - Protective effects of Juzentaihoto on adenine-induced chronic renal failure.
與倉史人; 伊藤都裕; DAI Yi; 辻野健; 辻野健
日本薬学会年会要旨集(Web), 2020 - Blood pressure control to avoid transient blood pressure elevation in patients treated with warfarin potassium.
赤木悠人; 高本光次郎; 坂本淳一; 伊藤都裕; 真鍋恵理; 石原正治; 辻野健
日本薬学会年会要旨集(Web), 2020 - 赤血球容積分布幅変動係数は心腎貧血症候群で上昇する
真鍋恵理; 辻野健; 辻野健; 辻野健; 伊藤都裕; 佐々木尚子; 志方敏幸; 坂本淳一; 高本光次郎; 高本光次郎; 朝倉正紀; 石原正治
医学と薬学, 2019 - ポリファーマシーがワルファリンカリウム服用中患者の抗凝固療法の質に及ぼす影響の検討
森上怜也; 村松和可子; 伊藤都裕; 高本光次郎; 坂本淳一; 水谷美穂; 夏井彩季; 石原正治; 辻野健; 辻野健
日本薬学会年会要旨集(CD-ROM), 2019 - 心房細動患者においてポリファーマシーが心原性脳塞栓症や脳出血のリスクスコアに及ぼす影響の検討
村松和可子; 森上怜也; 伊藤都裕; 高本光次郎; 坂本淳一; 水谷美穂; 夏井彩季; 石原正治; 真鍋恵理; 辻野健; 辻野健
日本薬学会年会要旨集(CD-ROM), 2019 - Dahl食塩感受性高血圧ラットに合併する貧血に対するエリスロポエチン製剤と鉄製剤の治療効果
小海龍矢; 伊藤都裕; 真鍋恵理; 石原正治; 辻野健; 辻野健
日本高血圧学会臨床高血圧フォーラム, 2019 - 降圧目標の遵守状況とそれにガイドライン変更が及ぼす影響について
中西香子; 久保亜里菜; 伊藤都裕; 坂本淳一; 高本光次郎; 真鍋恵理; 内藤由朗; 朝倉正紀; 石原正治; 辻野健; 辻野健
日本高血圧学会臨床高血圧フォーラム, 2019 - ワルファリンカリウム内服中の患者において血圧変動性が血圧コントロールに及ぼす影響の検討
久保亜里菜; 中西香子; 伊藤都裕; 坂本淳一; 高本光次郎; 真鍋恵理; 内藤由朗; 朝倉正紀; 石原正治; 辻野健
日本高血圧学会臨床高血圧フォーラム, 2019 - 高血圧患者において抗不安薬/睡眠薬の使用が予後に及ぼす影響
伊藤都裕; 坂本淳一; 志方敏幸; 高本光次郎; 高本光次郎; 真鍋恵理; 増山理; 辻野健; 辻野健; 辻野健
日本高血圧学会臨床高血圧フォーラムプログラム・抄録集(CD-ROM), 2018 - Dahl食塩感受性高血圧ラットにおける貧血にエリスロポエチン製剤は無効である
伊藤都裕; 真鍋恵理; 内藤由朗; 増山理; 辻野健; 辻野健
日本高血圧学会総会プログラム・抄録集(CD-ROM), 2018 - ガイドラインで推奨されていない薬剤数の増加は悪いアウトカムと関連する:J-MELODIC試験サブ解析
志方敏幸; 福井美保; 真鍋恵理; 高本光次郎; 坂本淳一; 伊藤都裕; 増山理; 辻野健; 辻野健; 辻野健
日本医療薬学会年会講演要旨集(Web), 2017 - Reduced Half-life of Erythrocytes in Dahl/Salt Sensitive Rats is the Cause of the Renal Proximal Tubule Damage
真鍋恵理; 伊藤都裕; 辻野健; 増山理
日本循環器学会学術集会(Web), 2017 - GLP-1analogueのExendin-4はERK1/2とJNKの阻害を介してアンギオテンシンIIによる血管平滑筋細胞の増殖と遊走を抑制する
長山功佑; 京谷陽司; 趙晶; 伊藤都裕; 小澤健太郎; 吉栖正典
日本薬理学会近畿部会プログラム・要旨集, 2015 - アンギオテンシンIIによる血管平滑筋細胞の増殖と遊走に対するGLP-1 analogueのExendin-4の抑制効果
長山功佑; 京谷陽司; 趙晶; 伊藤都裕; 小澤健太郎; 吉栖正典
日本循環薬理学会口演要旨集, 2015 - Peroxynitrite negatively regulates mitochondrial degradation via denitrosylation and tyrosine nitration of parkin
Kentaro Ozawa; Akira Komatsubara; Hiroto Kawafune; Jing Zhao; Yoji Kyotani; Satoyasu Ito; Kosuke Nagayama; Yuichi Tsuji; Masanori Yoshizumi
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2014 - オルメサルタンはJNK,p38のリン酸化を阻害することにより伸展刺激による細胞死を抑制する
伊藤都裕; 趙晶; 京谷陽司; 長山功佑; 辻優一; 小澤健太郎; 吉栖正典
日本薬理学会近畿部会プログラム・要旨集, 2014 - Nitric oxide increases activity of Parkin via S-nitrosylation
Kentaro Ozawa; Akira Komatsubara; Hiroto Kawafune; Jing Zhao; Yoji Kyotani; Satoyasu Ito; Kosuke Nagayama; Yuichi Tsuji; Yoshizumi Masanori
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013 - 一酸化窒素によるパーキンソン病関連タンパク質の制御機構
小澤健太郎; 小松原晃; 川舟広徒; 趙晶; 京谷陽司; 伊藤都裕; 長山功佑; 辻優一; 吉栖正典
日本NO学会学術集会プログラム抄録集, 2013 - 伸展負荷による血管平滑筋細胞死に対するアゼルニジピンの阻害効果の解析
趙晶; 小澤健太郎; 京谷陽司; 長山功佑; 伊藤都裕; 横田紘子; 小松原晃; 川舟広徒; 辻優一; 吉栖正典
日本薬理学会近畿部会プログラム・要旨集, 2013 - 伸展刺激による血管平滑筋細胞死に対するオルメサルタンの抑制効果
伊藤都裕; 趙昌; 京谷陽司; 長山功佑; 小松原晃; 川舟広徒; 辻優一; 小澤健太郎; 宇野雅之; 吉栖正典
日本薬理学会近畿部会プログラム・要旨集, 2013 - NO修飾によるパーキンソン病関連タンパク質Parkinの活性調節機構
小松原晃; 小澤健太郎; 川舟広徒; 辻優一; 趙晶; 京谷陽司; 伊藤都裕; 長山功佑; 吉栖正典
日本薬理学会近畿部会プログラム・要旨集, 2013 - Intermittent hypoxia promotes rat vascular muscle cells proliferation with up-regulation of erbB2 receptor and epidermal growth factor family
Yoji Kyotani; Shin Takasawa; Hiroyo Ota; Asako Hironaka; Akiyo Yamauchi; Sumiyo Tsuchida; Jing Zhao; Hiroshi Kimura; Satoyasu Ito; Masanori Yoshizumi
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012 - 膝関節および股関節全置換術後の深部静脈血栓症に対するアスピリンの予防投与と抗凝固療法の治療効果
野田哲史; 伊藤都裕; 赤羽理也; 河田明弘; 小西廣己; 千葉幹夫; 川崎拓; 松末吉隆; 山路昭
日本薬学会年会要旨集, 2008 - Spironolactone exhibits direct anti-atherosclerotic effects and inhibits LOX-1 expression in the L-NAME-induced hypertensive rat aorta
Toba H.; Inoue R.; Tsukamoto R.; Nakayama Y.; Ito S.; Kobara M.; Nakata T.
The 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, 2006, Oct. 2006
Research Themes
- Does liver fibrosis aggravate heart failure?
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2023 - 31 Mar. 2026 - Mechanisms of reduced lifespan of erythrocytes in chronic heart failure
Grant-in-Aid for Scientific Research (C)
01 Apr. 2018 - 31 Mar. 2023
