Last Updated :2024/12/13
Researcher Information
Research activity information
Paper
- 無再発のガン患者の血液中のexosome由来のmicroRNAのガン細胞増殖抑制作用
平田 豊; 高木 治行; 上嶋 英介; 児玉 大志; 和田 玲緒名; 山門 亨一郎
日本インターベンショナルラジオロジー学会雑誌, Apr. 2024 - 蛍光および発光遺伝子を導入したラット肝癌モデルの開発とInterventional Oncology基礎研究への応用
横田 侃己; 高木 治行; 平田 豊; 和田 玲緒奈; 児玉 大志; 山門 亨一郎
日本インターベンショナルラジオロジー学会雑誌, Apr. 2024 - Electrical stimulation mitigates muscle degradation shift in gene expressions during 12-h mechanical ventilation.
Hideki Nakai; Yutaka Hirata; Hidemasa Furue; Yoshitaka Oku
Scientific reports, Nov. 2023, [Reviewed] - Lenvatinib Mitigates Transarterial Embolization-Induced Polarization of Tumor-Associated Macrophages in a Rat Hepatocellular Carcinoma Model.
Eisuke Ueshima; Keitaro Sofue; Haruyuki Takaki; Yutaka Hirata; Hiroshi Kodama; Takuya Okada; Masato Yamaguchi; Koichiro Yamakado; Takamichi Murakami
Journal of vascular and interventional radiology : JVIR, Nov. 2023, [Reviewed] - 光イメージングで視認可能な担癌ラットモデルの開発(第二報)
高木 治行; 平田 豊; 上嶋 英介; 児玉 大志; 山門 亨一郎
日本インターベンショナルラジオロジー学会雑誌, Mar. 2022 - Hepatic Artery Embolization Enhances Expression of Programmed Cell Death 1 Ligand 1 in an Orthotopic Rat Hepatocellular Carcinoma Model: In Vivo and in Vitro Experimentation.
Haruyuki Takaki; Yutaka Hirata; Eisuke Ueshima; Hiroshi Kodama; Seiji Matsumoto; Reona Wada; Hitomi Suzuki; Keiji Nakasho; Koichiro Yamakado
Journal of vascular and interventional radiology : JVIR, Sep. 2020, [Reviewed] - Hepatic Artery Embolization Induces the Local Overexpression of Transforming Growth Factor β1 in a Rat Hepatoma Model.
Eisuke Ueshima; Hideyuki Nishiofuku; Haruyuki Takaki; Yutaka Hirata; Hiroshi Kodama; Toshihiro Tanaka; Kimihiko Kichikawa; Koichiro Yamakado; Takuya Okada; Keitaro Sofue; Masato Yamaguchi; Koji Sugimoto; Takamichi Murakami
Liver cancer, Jan. 2020, [Reviewed] - TRPM8 channel is involved in the ventilatory response to CO2 mediating hypercapnic Ca2+ responses.
Yutaka Hirata; Yoshiro Suzuki; Makoto Tominaga; Yoshitaka Oku
Respiratory physiology & neurobiology, May 2019, [Reviewed] - A knock-in mouse model of N-terminal R420W mutation of cardiac ryanodine receptor exhibits arrhythmogenesis with abnormal calcium dynamics in cardiomyocytes.
Noriyuki Okudaira; Masayoshi Kuwahara; Yutaka Hirata; Yoshitaka Oku; Hajime Nishio
Biochemical and biophysical research communications, Sep. 2014 - Interleukin-13 enhanced Ca2+ oscillations in airway smooth muscle cells.
Hisako Matsumoto; Yutaka Hirata; Kojiro Otsuka; Toshiyuki Iwata; Aya Inazumi; Akio Niimi; Isao Ito; Emiko Ogawa; Shigeo Muro; Hiroaki Sakai; Kazuo Chin; Yoshitaka Oku; Michiaki Mishima
Cytokine, Jan. 2012, [Reviewed] - How is the frequency of agonist-induced Ca2+ oscillation regulated in airway smooth muscle cells?
Yoshitaka Oku; Yutaka Hirata; Hisako Matsumoto; Michiaki Mishima
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010, [Reviewed] - TRP channels are involved in mediating hypercapnic Ca2+ responses in rat glia-rich medullary cultures independent of extracellular pH.
Yutaka Hirata; Yoshitaka Oku
Cell calcium, 2010, [Reviewed] - INTERLEUKIN-13 ENHANCES THE FREQUENCY OF LTD4-INDUCED Ca OSCILLATION IN HUMAN AIRWAY SMOOTH MUSCLE CELLS
Yutaka Hirata; Hisako Matsumoto; Kojiro Otsuka; Isao Ito; Emiko Ogawa; Shigeo Muro; Hiroaki Sakai; Akio Niimi; Michiaki Mishima; Yoshitaka Oku
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, [Reviewed]
Research Themes
- Development of hepatic artery embolization using cancer-accumulating contrast medium for delivery of microRNA therapeutics aiming at recurrence-free
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2022 - 31 Mar. 2025 - Elucidation of hypoxia-responsive genes that control recurrence after hepatic artery embolization and development of siRNA-loaded embolization preparations
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2020 - 31 Mar. 2023 - Novel therapeutic strategies based on macrophage polarization in the tumor microenvironment after hepatic arterial embolization.
Grant-in-Aid for Scientific Research (C)
Kobe University
01 Apr. 2020 - 31 Mar. 2023 - Factors related with acute exacerbation of interstitial pneumonia after lung radiofrequency ablation
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2019 - 31 Mar. 2022 - Elucidation of IL-33 expression mechanism by PAR-2 control aiming at application of asthma treatment
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2018 - 31 Mar. 2021 - Oncogenesis after hepatic arterial embolization
Grant-in-Aid for Young Scientists (B)
Kobe University
01 Apr. 2017 - 31 Mar. 2019 - Hepatic artery embolization and hypoxia: roles in the tumor recurrence and application for new treatment strategy
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2016 - 31 Mar. 2019 - The elucidation of central chemosensitive respiratory regulation by TRP channels expressed in glial cell.
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
2011 - 2013 - Astrocytes drive respiratory rhythm testing a new paradigm
Grant-in-Aid for Challenging Exploratory Research
Hyogo Medical University
2011 - 2012 - Role of chitinase like protein in chronic inflammatory airway diseases
Grant-in-Aid for Scientific Research (C)
Kyoto University
2010 - 2012 - The elucidation of mechanisms for central chemoreceptor
Grant-in-Aid for Young Scientists (B)
Hyogo College of Medicine
2007 - 2008