Last Updated :2025/09/13
Researcher Information
Research activity information
Paper
- Bacterial Lipopolysaccharide Induces PD-L1 Expression and an Invasive Phenotype of Oral Squamous Cell Carcinoma Cells.
Yuji Omori; Kazuma Noguchi; Mizuha Kitamura; Yuna Makihara; Takayuki Omae; Soutaro Hanawa; Kyohei Yoshikawa; Kazuki Takaoka; Hiromitsu Kishimoto
Cancers, Jan. 2024 - Usefulness of quantitative bone SPECT/CT for evaluating medication-related osteonecrosis of the jaw treatment response.
Kuniyasu Moridera; Kazuhiro Kitajima; Kyohei Yoshikawa; Kazuki Takaoka; Tatsuya Tsuchitani; Kazuma Noguchi; Hiromitsu Kishimoto; Koichiro Yamakado
Japanese journal of radiology, Jul. 2023 - Establishment of an oral squamous cell carcinoma cell line expressing vascular endothelial growth factor a and its two receptors.
Hanako Araki-Maeda; Mutsuki Kawabe; Yuji Omori; Koji Yamanegi; Kazunari Yoshida; Kyohei Yoshikawa; Kazuki Takaoka; Kazuma Noguchi; Yoshiro Nakano; Hiromitsu Kishimoto
Journal of dental sciences, Oct. 2022 - Establishment of a patient-derived mucoepidermoid carcinoma cell line with the CRTC1-MAML2 fusion gene.
Kazuma Noguchi; Shuji Kanda; Kazunari Yoshida; Yusuke Funaoka; Koji Yamanegi; Kyohei Yoshikawa; Kazuki Takaoka; Hiromitsu Kishimoto; Yoshiro Nakano
Molecular and clinical oncology, Mar. 2022 - Validity of a dysphagia screening test following resection for head and neck cancer.
Nobuhide Horii; Yoko Hasegawa; Ayumi Sakuramoto-Sadakane; Shyota Saito; Tomoki Nanto; Yuta Nakao; Kazuhisa Domen; Takahiro Ono; Hiromitsu Kishimoto
Irish journal of medical science, Feb. 2021 - Occurrence of a mucocele in a submandibular gland containing a sialolith: A case report
Kyohei Yoshikawa; Kazuma Noguchi; Koji Yamanegi; Masumi Nakanishi; Kazuki Takaoka; Hiromitsu Kishimoto
Oral Science International, Sep. 2020 - 〔Major achievements〕Novel insight into the management of bisphosphonate-related osteonecrosis of the jaw (BRONJ)
Hiromitsu Kishimoto; Kazuma Noguchi; Kazuki Takaoka
Japanese Dental Science Review, Nov. 2019 - Oral squamous cell carcinoma occurring secondary to oral lichen planus around the dental implant: A case report
Kazuma Noguchi; Kuniyasu Moridera; Yohei Sotsuka; Koji Yamanegi; Kazuki Takaoka; Hiromitsu Kishimoto
Oral Science International, Aug. 2019 - 〔Major achievements〕Long-term oral bisphosphonates delay healing after tooth extraction: a single institutional prospective study.
Atsushi Shudo; Hiromitsu Kishimoto; Kazuki Takaoka; Kazuma Noguchi
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, Jul. 2018, [Reviewed] - New paste for severe stomatitis in patients undergoing head-and-neck cancer radiotherapy and/or chemotherapy with oral appliance
Ayumi Sakuramoto; Yoko Hasegawa; Kazuma Sugahara; Yoshiyuki Komoda; Kana Hasegawa; Shinichi Hikasa; Mai Kurashita; Junya Sakai; Masahiro Arita; Kazuhiro Yasukawa; Hiromitsu Kishimoto
BMC Cancer, Mar. 2018 - Treatment with teriparatide for advanced bisphosphonate-related osteonecrosis of the jaw around dental implants: a case report
Yusuke Zushi; Kazuki Takaoka; Joji Tamaoka; Miho Ueta; Kazuma Noguchi; Hiromitsu Kishimoto
International Journal of Implant Dentistry, Dec. 2017 - Molecular analysis of keratocystic odontogenic tumor cell lines derived from sporadic and basal cell nevus syndrome patients
Kazuma Noguchi; Keiko Wakai; Tohru Kiyono; Mutsuki Kawabe; Kyohei Yoshikawa; Tomoko Hashimoto-Tamaoki; Hiromitsu Kishimoto; Yoshiro Nakano
INTERNATIONAL JOURNAL OF ONCOLOGY, Dec. 2017, [Reviewed] - Clinical study of splint therapeutic efficacy for the relief of temporomandibular joint discomfort
Yoko Hasegawa; Naoya Kakimoto; Seiki Tomita; Masanori Fujiwara; Reichi Ishikura; Hiromitsu Kishimoto; Kosuke Honda
Journal of Cranio-Maxillofacial Surgery, Nov. 2017 - Change in tongue pressure in patients with head and neck cancer after surgical resection.
Yoko Hasegawa; Kazuma Sugahara; Tatsuyuki Fukuoka; Shota Saito; Ayumi Sakuramoto; Nobuhide Horii; Saori Sano; Kana Hasegawa; Yuta Nakao; Tomoki Nanto; Kanenori Kadoi; Kuniyasu Moridera; Kazuma Noguchi; Kazuhisa Domen; Hiromitsu Kishimoto
Odontology, Oct. 2017 - Oral management for creating functional oral cavity in eating
Kishimoto Hiromitsu; Hasegawa Yoko; Takaoka Kazuki; Noguchi Kazuma
Journal of Japanese Society for Parenteral and Enteral Nutrition, 2016 - Prevalence of temporomandibular disorders among junior high school students who play wind instruments
Eriko Yasuda; Kosuke Honda; Yoko Hasegawa; Eiko Matsumura; Masanori Fujiwara; Makoto Hasegawa; Hiromitsu Kishimoto
International Journal of Occupational Medicine and Environmental Health, 2016 - Dental implant treatment in a young woman after marginal mandibulectomy for treatment of mandibular gingival carcinoma: a case report
Kazuki Takaoka; Emi Segawa; Michiyo Yamamura; Yusuke Zushi; Masahiro Urade; Hiromitsu Kishimoto
International Journal of Implant Dentistry, Dec. 2015 - Establishment of an Animal Model of Bisphosphonate-Related Osteonecrosis of the Jaws in Spontaneously Diabetic Torii Rats
Kazuki Takaoka; Michiyo Yamamura; Toshihiro Nishioka; Tetsuya Abe; Joji Tamaoka; Emi Segawa; Masami Shinohara; Haruyasu Ueda; Hiromitsu Kishimoto; Masahiro Urade
PLOS ONE, Dec. 2015, [Reviewed] - The Hippo pathway transcriptional co-activator, YAP, confers resistance to cisplatin in human oral squamous cell carcinoma
Kyohei Yoshikawa; Kazuma Noguchi; Yoshiro Nakano; Michiyo Yamamura; Kazuki Takaoka; Tomoko Hashimoto-Tamaoki; Hiromitsu Kishimoto
INTERNATIONAL JOURNAL OF ONCOLOGY, Jun. 2015, [Reviewed] - Sodium valproate, a histone deacetylase inhibitor, modulates the vascular endothelial growth inhibitor-mediated cell death in human osteosarcoma and vascular endothelial cells
Koji Yamanegi; Mutsuki Kawabe; Hiroyuki Futani; Hiroshi Nishiura; Naoko Yamada; Nahoko Kato-Kogoe; Hiromitsu Kishimoto; Shinichi Yoshiya; Keiji Nakasho
INTERNATIONAL JOURNAL OF ONCOLOGY, May 2015, [Reviewed] - Osteonecrosis of the jaw in an AIDS patient: a case report.
Yusuke Zushi; Kazuma Noguchi; Kuniyasu Moridera; Kazuki Takaoka; Hiromitsu Kishimoto
AIDS research and therapy, 2015 - Effect of a nitric oxide synthase inhibitor and a CXC chemokine receptor-4 antagonist on tumor growth and metastasis in a xenotransplanted mouse model of adenoid cystic carcinoma of the oral floor
Kazuki Takaoka; Sayaka Hidaka; Susumu Hashitani; Emi Segawa; Michiyo Yamamura; Noriaki Tanaka; Yusuke Zushi; Kazuma Noguchi; Hiromitsu Kishimoto; Masahiro Urade
INTERNATIONAL JOURNAL OF ONCOLOGY, Sep. 2013, [Reviewed] - Unicystic ameloblastoma metastasizing to multiple cervical lymph nodes.
Kazuma Noguchi; Hiromitsu Kishimoto; Koji Yamanegi; Kuniyasu Moridera; Kazuki Takaoka; Masahiro Urade
Journal of surgical case reports, May 2013 - Wernicke's encephalopathy after chemoradiotherapy for tongue cancer: Report of a case
Mutsuki Kawabe; Kazuma Noguchi; Hiromitsu Kishimoto; Masahiro Urade
Oral Science International, May 2013, [Reviewed] - Functional analysis of Zyxin in cell migration and invasive potential of oral squamous cell carcinoma cells
Michiyo Yamamura; Kazuma Noguchi; Yoshiro Nakano; Emi Segawa; Yusuke Zushi; Kazuki Takaoka; Hiromitsu Kishimoto; Tomoko Hashimoto-Tamaoki; Masahiro Urade
International Journal of Oncology, Mar. 2013, [Reviewed] - Diffuse sclerosing osteomyelitis of the mandible successfully treated with pamidronate: a long-term follow-up report
Masahiro Urade; Kazuma Noguchi; Kazuki Takaoka; Kuniyasu Moridera; Hiromitsu Kishimoto
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, Oct. 2012, [Reviewed] - Up-regulation of neutrophil gelatinase-associated lipocalin in oral squamous cell carcinoma: Relation to cell differentiation
Takashi Hiromoto; Kazuma Noguchi; Michiyo Yamamura; Yusuke Zushi; Emi Segawa; Kazuki Takaoka; Kuniyasu Moridera; Hiromitsu Kishimoto; Masahiro Urade
ONCOLOGY REPORTS, Dec. 2011, [Reviewed] - Inhibitory effect of vitamin D-binding protein-derived macrophage activating factor on DMBA-induced hamster cheek pouch carcinogenesis and its derived carcinoma cell line
Yukiyo Toyohara; Susumu Hashitani; Hiromitsu Kishimoto; Kazuma Noguchi; Nobuto Yamamoto; Masahiro Urade
Oncology Letters, Jul. 2011, [Reviewed] - Novel PTCH1 mutations in Japanese Nevoid basal cell carcinoma syndrome patients: two familial and three sporadic cases including the first Japanese patient with medulloblastoma
Midori Fujii; Kazuma Noguchi; Masahiro Urade; Yukoh Muraki; Kuniyasu Moridera; Hiromitsu Kishimoto; Tomoko Hashimoto-Tamaoki; Yoshiro Nakano
JOURNAL OF HUMAN GENETICS, Apr. 2011, [Reviewed] - Promotion of hematogenous metastatic potentials in human KB carcinoma cells with overexpression of cyclooxygenase-2
Emi Segawa; Hiromitsu Kishimoto; Kazuki Takaoka; Kazuma Noguchi; Susumu Hashitani; Kazunari Sakurai; Masahiro Urade
ONCOLOGY REPORTS, Sep. 2010, [Reviewed] - Antitumor effects of inhibitors of nitric oxide synthase or cyclooxygenase-2 on human KB carcinoma cells overexpressing COX-2
Nao Ohtsu; Kazuki Takaoka; Emi Segawa; Susumu Hashitani; Kazuma Noguchi; Hiromitsu Kishimoto; Masahiro Urade
ONCOLOGY REPORTS, Jul. 2010, [Reviewed] - Inhibitory effect of sulindac on DMBA-induced hamster cheek pouch carcinogenesis and its derived cell line
Emi Segawa; Susumu Hashitani; Yukiyo Toyohara; Hiromitsu Kishimoto; Kazuma Noguchi; Kazuki Takaoka; Masahiro Urade
ONCOLOGY REPORTS, Apr. 2009, [Reviewed] - Relations among expression of CXCR4, histological patterns, and metastatic potential in adenoid cystic carcinoma of the head and neck
Yusuke Zushi; Kazuma Noguchi; Susumu Hashitani; Kazunari Sakurai; Emi Swgawa; Kazuki Takaoka; Yukiyo Toyohara; Noriaki Tanaka; Hiromitsu Kishimoto; Masahiro Urade
INTERNATIONAL JOURNAL OF ONCOLOGY, Dec. 2008, [Reviewed] - In vitro susceptibility to anticancer agents of the human KB carcinoma cell line transfected with COX-2 cDNA
Kazuki Takaoka; Hiromitsu Kishimoto; Emi Segawa; Nao Otsu; Yusuke Zushi; Susumu Hashitani; Kazuma Noguchi; Masahiro Urade
ONCOLOGY REPORTS, Sep. 2008, [Reviewed] - Expression of cyclooxygenase-2 and DNA topoisomerase II alpha in precancerous and cancerous lesions of the oral mucosa
Emi Segawa; Kazunari Sakurai; Hiromitsu Kishimoto; Kazuki Takaoka; Kazuma Noguchi; Susumu Hashitani; Seiichi Hirota; Masahiro Urade
ORAL ONCOLOGY, Jul. 2008, [Reviewed] - Prognostic significance of cyclooxygenase-2 and DNA topoisomerase II alpha expression in oral carcinoma
Kazunari Sakurai; Masahiro Urade; Kazuma Noguchi; Susumu Hashitani; Kazuki Takaoka; Emi Segawa; Hiromitsu Kishimoto
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, Nov. 2007, [Reviewed] - Elevated cell migration, invasion and tumorigenicity in human KB carcinoma cells transfected with COX-2 cDNA
Kazuki Takaoka; Hiromitsu Kishimoto; Emi Segawa; Susumu Hashitani; Yusuke Zushi; Kazuma Noguchi; Kazunari Sakurai; Masahiro Urade
INTERNATIONAL JOURNAL OF ONCOLOGY, Nov. 2006, [Reviewed] - 食道癌手術患者の周術期口腔管理による術後肺炎予防
岸本 裕充; 野口 一馬; 高岡 一樹; 浦出 雅裕
日本口腔感染症学会雑誌, Oct. 2006 - ビスホスホネートに起因すると考えられる顎骨壊死の2例
田中 徳昭; 高岡 一樹; 橋谷 進; 岸本 裕充; 頭司 雄介; 瀬川 英美; 櫻井 一成; 浦出 雅裕
日本口腔外科学会雑誌, Sep. 2006 - Changes of histological and biological features by serial passages in a human adenoid cystic carcinoma line transplantable in nude mice
S Hashitani; K Noguchi; Y Manno; K Moridera; K Takaoka; N Nishimura; H Kishimoto; K Sakurai; M Urade
ONCOLOGY REPORTS, Apr. 2005, [Reviewed] - Promotion of cell differentiation, and suppression of cell growth and cyclooxygenase-2 expression by differentiation-inducing agents in human oral squamous carcinoma SCC25 cells
J Kuroda; M Urade; H Kishimoto; K Noguchi; S Hashitani; K Sakurai; N Nishimura; T Hashimoto-Tamaoki
INTERNATIONAL JOURNAL OF ONCOLOGY, Feb. 2005, [Reviewed] - Establishment of a new cell line with neuronal differentiation derived from small cell neuroendocrine carcinoma of the maxillary sinus
K Noguchi; M Urade; H Kishimoto; J Kuroda; K Moridera; K Sakurai
ONCOLOGY, 2004, [Reviewed] - Small cell neuroendocrine carcinoma of the maxillary sinus - A case report and nude mouse transplantable model
K Noguchi; M Urade; K Sakurai; N Nishimura; S Hashitani; H Kishimoto
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, May 2002, [Reviewed] - Increased expression of cyclooxygenase-2 in human salivary gland tumors
Kazunari Sakurai; Masahiro Urade; Kazuma Noguchi; Hiromitsu Kishimoto; Miki Ishibashi; Hitoshi Yasoshima; Tadashi Yamamoto; Akira Kubota
Pathology International, 2001 - Common variable immunodeficiency with unusual vegetative lesions of the tongue and labial mucosa - A case report
H Kishimoto; M Urade; K Noguchi; K Sakurai
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, Jan. 2001, [Reviewed] - Increased expression of c-erbB-3 protein and proliferating cell nuclear antigen during development of verrucous carcinoma of the oral mucosa
K Sakurai; M Urade; Y Takahashi; H Kishimoto; K Noguchi; H Yasoshima; A Kubota
CANCER, Dec. 2000, [Reviewed] - Two cases of upper gingival carcinoma with metastasis to the lateral retropharyngeal node (Rouviere node )
KISHIMOTO Hiromitsu; URADE Masahiro; ARIMOTO Takamasa; NOGUCHI Kazuma; FUKUTSUJI Miki; KAWANAKA Masao; TAKAHASHI Yumiko; YANAGISAWA Takamichi; YOSHIOKA Wataru
Journal of Oral Surgery Society of Japan, Dec. 1995 - A case of adenoid squamous cell carcinoma of the maxillary sinus with high levels of serum SCC antigen and CEA
KISHIMOTO Hiromitsu; URADE Masahiro; ARIMOTO Takamasa; SAKURAI Kazunari; YANAGISAWA Takamichi; YOSHIOKA Wataru
Journal of Oral Surgery Society of Japan, Dec. 1995 - Experience in treating a gingival carcinoma patient with autoimmune leukopenia by combination therapy with human granulocyte colony stimulating factor.
KISHIMOTO Hiromitsu; URADE Masahiro; SUZUTA Akihiko; TANAKA Shunsuke; YANAGISAWA Takamichi; YOSHIOKA Wataru
Journal of Oral Surgery Society of Japan, 1993
MISC
- Usefulness of Quantitative Bone SPECT/CT for Evaluating Treatment Response in a Patient with Mandibular Osteomyelitis
Kazuhiro Kitajima; Kazuma Noguchi; Kuniyasu Moridera; Hiromitsu Kishimoto; Tatsuya Tsuchitani; Yoshiyuki Takahashi; Shungo Furudoi; Koichiro Yamakado
Case Reports in Oncology, 11 Jun. 2021 - Establishment and molecular analysis of immortalized keratocystic odontogenic tumor cell lines derived from sporadic and Gorlin syndrome patients
Yoshiro Nakano; Kazuma Noguchi; Hiromitsu Kishimoto; Tomoko Hashimoto-Tamaoki
MECHANISMS OF DEVELOPMENT, Jul. 2017 - Functional analysis of Zyxin in cell migration and invasive potential of oral squamous cell carcinoma cells (vol 42, pg 873, 2013)
Michiyo Yamamura; Kazuma Noguchi; Yoshiro Nakano; Emi Segawa; Yusuke Zushi; Kazuki Takaoka; Hiromitsu Kishimoto; Tomoko Hashimoto-Tamaoki; Masahiro Urade
INTERNATIONAL JOURNAL OF ONCOLOGY, Nov. 2016 - Assess Dental Plaque and Suction-Extricated Bacteria Adequately
Hiromitsu Kishimoto; Masahiro Urade
CHEST, Feb. 2010 - Mechanical tooth cleaning before chlorhexidine application
Hiromitsu Kishimoto; Masahiro Urade
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Feb. 2007 - 〔Major achievements〕Overexpression of SCC antigen and cyclins in an adenoid squamous carcinoma cell line derived from the maxillary sinus
H Kishimoto; M Urade; T Hashimoto-Tamaoki; J Furuyama
INTERNATIONAL JOURNAL OF ONCOLOGY, Feb. 2001 - Isolation and characterisation of adenoid squamous carcinoma cells highly producing SCC antigen and CEA from carcinoma of the maxillary sinus
H Kishimoto; M Urade; K Sakurai; K Noguchi
ORAL ONCOLOGY, Jan. 2000 - A case of incomplete CREST syndrome associated with dry mouth
Hiromitsu KISHIMOTO; Yukiyo MANNO; Kazuki TAKAOKA; Jun NATORI; Kazunari SAKURAI; Masahiro URADE
Japanese Journal of Oral and Maxillofacial Surgery, 1999 - Study of hospital infection control against MRSA in inpatients undergoing oral surgery
KISHIMOTO Hiromitsu; URADE Masahiro; MATSUMOTO Suwako; ARIMOTO Takamasa; NOGUCHI Kazuma; HASHITANI Susumu; YANAGISAWA Takamichi; WADA Yasunao; YOSHIOKA Wataru
Journal of Oral Surgery Society of Japan, 1996 - Clinical study on prophylactic effectiveness of antimicrobial regimen on postoperative infection in oral surgery
Hiromitsu Kishimoto; Masahiro Urade; Takamasa Arimoto; Shigeki Satake; Kazuma Noguchi; Wataru Yoshioka
ORAL THERAPEUTICS AND PHARMACOLOGY, 1995
Affiliated academic society
Research Themes
- The development of novel traetment strategy for the adipose tissue infiltration of oral squamous cell carcinoma
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2025 - 31 Mar. 2028 - 歯科口腔外科領域における感染症対策
- 口腔癌の腫瘍マーカーに関する研究
- Infection Control in Dentistry and Oral Surgery
- Study on Tumor Markers of Oral Cancer
