Last Updated :2025/10/31
Researcher Information
Research activity information
Paper
- Predictors of the Need for Additional Postoperative Treatment for Eosinophilic Chronic Rhinosinusitis.
Takahiro Saito; Katsuya Fushimi; Tomoki Hirose; Takenori Haruna; Kenzo Tsuzuki
ORL; journal for oto-rhino-laryngology and its related specialties, 2025 - Role of nasal polyp-derived innate lymphoid cells in staphylococcal enterotoxin-induced cellular responses.
Kengo Kanai; Aiko Oka; Shin Kariya; Tazuko Fujiwara; Takaya Higaki; Seiichiro Makihara; Takenori Haruna; Maki Akamatsu; Kazunori Nishizaki; Mizuo Ando; Mitsuhiro Okano
Allergology international : official journal of the Japanese Society of Allergology, Jul. 2024 - The add-on effect of an intranasal antihistamine with an intranasal corticosteroid in Japanese cedar pollinosis.
Takenori Haruna; Shin Kariya; Takaya Higaki; Aya Murai; Kengo Kanai; Aiko Oka; Maki Akamatsu; Mizuo Ando; Kazunori Nishizaki; Mitsuhiro Okano
Auris, nasus, larynx, Feb. 2023 - Mapping naso-ocular symptom scores to EQ-5D-5L utility values in Japanese cedar pollinosis.
Hiroshi Kumanomidou; Kengo Kanai; Aiko Oka; Takenori Haruna; Yuji Hirata; Sei-Ichiro Makihara; Takaya Higaki; Maki Akamatsu; Yoshitaka Okamoto; Shunya Ikeda; Mitsuhiro Okano
Allergology international : official journal of the Japanese Society of Allergology, Apr. 2022 - Role of salivary microbiome in IL-10 production and efficacy of sublingual immunotherapy.
Aiko Oka; Masanori Kidoguchi; Shin Kariya; Tazuko Fujiwara; Atsushi Yuta; Hiromi Miyashita; Takaya Higaki; Yukiko Ogawa; Kengo Kanai; Sei-Ichiro Makihara; Takenori Haruna; Jun Kunisawa; Naoto Adachi; Keisuke Koyama; Rieko Ii; Emiko Noguchi; Shigeharu Fujieda; Kazunori Nishizaki; Mitsuhiro Okano
Allergy, Aug. 2021 - Effect of Prostaglandin D2 on mRNA Expression of Three Isoforms of Hyaluronic Acid Synthase in Nasal Polyp Fibroblasts.
Yuji Hirata; Shin Kariya; Kengo Kanai; Tazuko Fujiwara; Sei-Ichiro Makihara; Ryotaro Omichi; Takaya Higaki; Takenori Haruna; Aiko Oka; Kazunori Nishizaki; Mitsuhiro Okano
American journal of rhinology & allergy, Jan. 2021 - Association between the NOS2 pentanucleotide repeat polymorphism and risk of postoperative recurrence of chronic rhinosinusitis with nasal polyps in a Japanese population.
Masanori Kidoguchi; Kanako Yoshida; Emiko Noguchi; Takako Nakamura; Wataru Morii; Takenori Haruna; Mitsuhiro Okano; Yukiko Yamashita; Shinichi Haruna; Masayo Hasegawa; Naohiro Yoshida; Takahiro Ninomiya; Yoshimasa Imoto; Masafumi Sakashita; Tetsuji Takabayashi; Shigeharu Fujieda
Allergology international : official journal of the Japanese Society of Allergology, Oct. 2020 - Serum IgG4 as a biomarker reflecting pathophysiology and post-operative recurrence in chronic rhinosinusitis.
Aiko Oka; Takahiro Ninomiya; Tazuko Fujiwara; Soshi Takao; Yasuharu Sato; Yuka Gion; Akira Minoura; Shin-Ichi Haruna; Naohiro Yoshida; Yasunori Sakuma; Kenji Izuhara; Junya Ono; Masami Taniguchi; Takenori Haruna; Takaya Higaki; Shin Kariya; Takahisa Koyama; Tetsuji Takabayashi; Yoshimasa Imoto; Masafumi Sakashita; Masanori Kidoguchi; Kazunori Nishizaki; Shigeharu Fujieda; Mitsuhiro Okano
Allergology international : official journal of the Japanese Society of Allergology, Jul. 2020 - Corrigendum to "Effect of prostaglandin D2 on VEGF release by nasal polyp fibroblasts" [Allergol Int 65 (2016) 414-419].
Kengo Kanai; Mitsuhiro Okano; Tazuko Fujiwara; Shin Kariya; Takenori Haruna; Ryotaro Omichi; Sei-Ichiro Makihara; Yuji Hirata; Kazunori Nishizaki
Allergology international : official journal of the Japanese Society of Allergology, Jan. 2020 - The efficacy of OK-432 sclerotherapy on thyroglossal duct cyst and the influence on a subsequent surgical procedure.
Tomoyasu Tachibana; Shin Kariya; Yorihisa Orita; Takuma Makino; Takenori Haruna; Yuko Matsuyama; Yasutoshi Komatsubara; Yuto Naoi; Michihiro Nakada; Yoji Wani; Soichiro Fushimi; Machiko Hotta; Katsuya Haruna; Tami Nagatani; Yasuharu Sato; Kazunori Nishizaki
Acta oto-laryngologica, Sep. 2019 - Spontaneous closure of traumatic tympanic membrane perforation following long-term observation.
Tomoyasu Tachibana; Shin Kariya; Yorihisa Orita; Takuma Makino; Takenori Haruna; Yuko Matsuyama; Yasutoshi Komatsubara; Yuto Naoi; Michihiro Nakada; Yohei Noda; Yasuharu Sato; Kazunori Nishizaki
Acta oto-laryngologica, Jun. 2019 - Significance of IgG4-positive cells in severe eosinophilic chronic rhinosinusitis.
Takahisa Koyama; Shin Kariya; Yasuharu Sato; Yuka Gion; Takaya Higaki; Takenori Haruna; Tazuko Fujiwara; Akira Minoura; Soshi Takao; Yorihisa Orita; Kengo Kanai; Masami Taniguchi; Kazunori Nishizaki; Mitsuhiro Okano
Allergology international : official journal of the Japanese Society of Allergology, Apr. 2019 - Determining an Appropriate Time to Start Prophylactic Treatment with Intranasal Corticosteroids in Japanese Cedar Pollinosis.
Takenori Haruna; Shin Kariya; Takaya Higaki; Sei-Ichiro Makihara; Kengo Kanai; Yasutoshi Komatsubara; Aiko Oka; Kazunori Nishizaki; Mitsuhiro Okano
Medical sciences (Basel, Switzerland), Jan. 2019 - Role of whole saliva in the efficacy of sublingual immunotherapy in seasonal allergic rhinitis.
Takenori Haruna; Shin Kariya; Tazuko Fujiwara; Atsushi Yuta; Takaya Higaki; Pengfei Zhao; Yukiko Ogawa; Kengo Kanai; Yuji Hirata; Aiko Oka; Kazunori Nishizaki; Mitsuhiro Okano
Allergology international : official journal of the Japanese Society of Allergology, Jan. 2019 - Factors that prolong the duration of recovery in acute rhinosinusitis with orbital complications.
Tomoyasu Tachibana; Shin Kariya; Yorihisa Orita; Michihiro Nakada; Takuma Makino; Takenori Haruna; Yuko Matsuyama; Yasutoshi Komatsubara; Yuto Naoi; Yasuharu Sato; Kazunori Nishizaki
Acta oto-laryngologica, Jan. 2019 - [THE EXAMINATION OF IGE AND PERIPHERAL BLOOD MONONUCLEAR CELLS RESPONSES TO FLOUR EXTRACTS IN A BAKER'S RHINITIS PATIENT].
Takenori Haruna; Mitsuhiro Okano; Tazuko Fujiwara; Takaya Higaki; Shin Kariya; Seiichiro Makihara; Kengo Kanai; Tomoyasu Tachibana; Yuko Matsuyama; Yasutoshi Komatsubara; Yuto Naoi; Kazunori Nishizaki
Arerugi = [Allergy], 2019 - Periostin as a novel biomarker for postoperative recurrence of chronic rhinosinitis with nasal polyps.
Takahiro Ninomiya; Emiko Noguchi; Takenori Haruna; Masayo Hasegawa; Takuto Yoshida; Yukiko Yamashita; Mitsuhiro Okano; Naohiro Yoshida; Shinichi Haruna; Yasunori Sakuma; Shoichiro Ohta; Junya Ono; Kenji Izuhara; Masafumi Okada; Masanori Kidoguchi; Takahiro Tokunaga; Masayuki Okamoto; Masafumi Kanno; Masafumi Sakashita; Tetsuji Takabayashi; Norihiko Narita; Shigeharu Fujieda
Scientific reports, Jul. 2018 - Association between impaired IL-10 production following exposure to Staphylococcus aureus enterotoxin B and disease severity in eosinophilic chronic rhinosinusitis.
Takenori Haruna; Shin Kariya; Tazuko Fujiwara; Takaya Higaki; Seiichiro Makihara; Kengo Kanai; Rumi Fujiwara; Satoshi Iwasaki; Yoshihiro Noguchi; Kazunori Nishizaki; Mitsuhiro Okano
Allergology international : official journal of the Japanese Society of Allergology, Jul. 2018 - Pulmonary function in patients with eosinophilic chronic rhinosinusitis.
Kensuke Uraguchi; Shin Kariya; Seiichiro Makihara; Mitsuhiro Okano; Takenori Haruna; Aiko Oka; Rumi Fujiwara; Yohei Noda; Kazunori Nishizaki
Auris, nasus, larynx, Jun. 2018 - Evaluation of a new and simple classification for endoscopic sinus surgery.
Kengo Kanai; Mitsuhiro Okano; Takenori Haruna; Takaya Higaki; Ryotaro Omichi; Sei-Ichiro Makihara; Munechika Tsumura; Shin Kariya; Yuji Hirata; Kazunori Nishizaki
Allergy & rhinology (Providence, R.I.), Oct. 2017 - The impact of chronic rhinosinusitis on long-term survival in lung transplantation recipients.
Shin Kariya; Mitsuhiro Okano; Takahiro Oto; Takaya Higaki; Takenori Haruna; Yohei Noda; Kazunori Nishizaki
Acta oto-laryngologica, May 2017 - IL-22/IL-22R1 signaling regulates the pathophysiology of chronic rhinosinusitis with nasal polyps via alteration of MUC1 expression.
Yasuyuki Noyama; Mitsuhiro Okano; Tazuko Fujiwara; Shin Kariya; Takaya Higaki; Takenori Haruna; Sei-Ichiro Makihara; Kengo Kanai; Takahisa Koyama; Masami Taniguchi; Jun-Ichi Ishitoya; Akira Kanda; Yoshiki Kobayashi; Mikiya Asako; Koichi Tomoda; Kazunori Nishizaki
Allergology international : official journal of the Japanese Society of Allergology, Jan. 2017 - Effect of prostaglandin D2 on VEGF release by nasal polyp fibroblasts.
Kengo Kanai; Mitsuhiro Okano; Tazuko Fujiwara; Shin Kariya; Takenori Haruna; Ryotaro Omichi; Sei-Ichiro Makihara; Yuji Hirata; Kazunori Nishizaki
Allergology international : official journal of the Japanese Society of Allergology, Oct. 2016 - Effect of intranasal corticosteroid on pre-onset activation of eosinophils and mast cells in experimental Japanese cedar pollinosis.
Yasuyuki Noyama; Mitsuhiro Okano; Tazuko Fujiwara; Shin Kariya; Sei-Ichiro Makihara; Takenori Haruna; Kengo Kanai; Takaya Higaki; Kazunori Nishizaki
Allergology international : official journal of the Japanese Society of Allergology, Jul. 2016 - Regulatory effect of TLR3 signaling on staphylococcal enterotoxin-induced IL-5, IL-13, IL-17A and IFN-γ production in chronic rhinosinusitis with nasal polyps.
Mitsuhiro Okano; Tazuko Fujiwara; Shin Kariya; Takaya Higaki; Sei-ichiro Makihara; Takenori Haruna; Yasuyuki Noyama; Takahisa Koyama; Ryotaro Omichi; Yorihisa Orita; Kentaro Miki; Kengo Kanai; Kazunori Nishizaki
Allergology international : official journal of the Japanese Society of Allergology, Jan. 2016 - Pulmonary function in never-smoker patients with chronic rhinosinusitis.
Shin Kariya; Mitsuhiro Okano; Takaya Higaki; Yasuyuki Noyama; Takenori Haruna; Kazunori Nishizaki
International forum of allergy & rhinology, Nov. 2015 - Staphylococcal protein A-formulated immune complexes suppress enterotoxin-induced cellular responses in nasal polyps.
Mitsuhiro Okano; Tazuko Fujiwara; Shin Kariya; Takenori Haruna; Takaya Higaki; Yasuyuki Noyama; Sei-ichiro Makihara; Kengo Kanai; Kazunori Nishizaki
The Journal of allergy and clinical immunology, Aug. 2015 - Macrophage Migration Inhibitory Factor Deficiency Causes Prolonged Hearing Loss After Acoustic Overstimulation.
Shin Kariya; Mitsuhiro Okano; Yukihide Maeda; Haruka Hirai; Takaya Higaki; Yasuyuki Noyama; Takenori Haruna; Jun Nishihira; Kazunori Nishizaki
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, Jul. 2015 - [Eosinophilic chronic rhinosinusitis].
Shigeharu Fujieda; Masafumi Sakashita; Takahiro Tokunaga; Mitsuhiro Okano; Takenori Haruna; Mamoru Yoshikawa; Nobuyoshi Ohtori; Daiya Asaka; Shinichi Haruna; Tsuguhisa Nakayama; Junichi Ishitoya; Yasunori Sakuma; Katsuhiro Hirakawa; Sachio Takeno; Tetsuo Himi; Nobuhiko Seki; Yukiko Iino; Naohiro Yoshida; Masayoshi Kobayashi; Hiroshi Sakaida; Kenji Kondo; Tatsuya Yamasoba; Takaki Miwa; Kanako Yamada; Ryo Kawata; Tetsuya Terada; Hideyuki Kawauchi; Ichiro Morikura; Katsuhisa Ikeda; Junko Murata; Hiroki Ikeda; Emiko Noguchi; Mayumi Tamari; Tomomitsu Hirota; Yoshimasa Imoto; Tetsuji Takabayashi; Kaori Tomita; Takahiro Ninomiya; Taiyo Morikawa; Mitsuyoshi Urashima
Arerugi = [Allergy], Feb. 2015 - Cellular responses to Staphylococcus aureus alpha-toxin in chronic rhinosinusitis with nasal polyps.
Mitsuhiro Okano; Tazuko Fujiwara; Shin Kariya; Takaya Higaki; Takenori Haruna; Osamu Matsushita; Yohei Noda; Seiichiro Makihara; Kengo Kanai; Yasuyuki Noyama; Masami Taniguchi; Kazunori Nishizaki
Allergology international : official journal of the Japanese Society of Allergology, Dec. 2014 - Role of macrophage migration inhibitory factor in age-related hearing loss
Shin Kariya; Mitsuhiro Okano; Yukihide Maeda; Haruka Hirai; Takaya Higaki; Yasuyuki Noyama; Takenori Haruna; Jun Nishihira; Kazunori Nishizaki
Neuroscience, Oct. 2014, [Reviewed] - Chronic rhinosinusitis patients have decreased lung function.
Shin Kariya; Mitsuhiro Okano; Takaya Higaki; Yasuyuki Noyama; Takenori Haruna; Hisashi Ishihara; Takuma Makino; Tomoo Onoda; Kazunori Nishizaki
International forum of allergy & rhinology, Oct. 2014 - Local expression of interleukin-17a is correlated with nasal eosinophilia and clinical severity in allergic rhinitis.
Seiichiro Makihara; Mitsuhiro Okano; Tazuko Fujiwara; Yohei Noda; Takaya Higaki; Tomomi Miyateke; Kengo Kanai; Takenori Haruna; Shin Kariya; Kazunori Nishizaki
Allergy & rhinology (Providence, R.I.), Apr. 2014 - Pulmonary function in patients with chronic rhinosinusitis and allergic rhinitis
Shin Kariya; Mitsuhiro Okano; Takahiro Oto; Takaya Higaki; Seiichiro Makihara; Takenori Haruna; Kazunori Nishizaki
The Journal of Laryngology & Otology, Mar. 2014, [Reviewed] - Determining minimal clinically important differences in Japanese cedar/cypress pollinosis patients.
Takaya Higaki; Mitsuhiro Okano; Shin Kariya; Tazuko Fujiwara; Takenori Haruna; Haruka Hirai; Aya Murai; Minoru Gotoh; Kimihiro Okubo; Shuji Yonekura; Yoshitaka Okamoto; Kazunori Nishizaki
Allergology international : official journal of the Japanese Society of Allergology, Dec. 2013 - Neutralizing antibody against granulocyte/macrophage colony-stimulating factor inhibits inflammatory response in experimental otitis media.
Shin Kariya; Mitsuhiro Okano; Takaya Higaki; Seiichiro Makihara; Takenori Haruna; Motoharu Eguchi; Kazunori Nishizaki
The Laryngoscope, Jun. 2013 - Characterization of IL-18 expression and release in the pathogenesis of chronic rhinosinusitis.
Mitsuhiro Okano; Tazuko Fujiwara; Seiichiro Makihara; Rumi Fujiwara; Takaya Higaki; Shin Kariya; Yohei Noda; Takenori Haruna; Kazunori Nishizaki
International archives of allergy and immunology, 2013 - Early interventional treatment with intranasal corticosteroids compared with postonset treatment in pollinosis.
Takaya Higaki; Mitsuhiro Okano; Seiichiro Makihara; Tazuko Fujiwara; Takenori Haruna; Yohei Noda; Shin Kariya; Kazunori Nishizaki
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, Dec. 2012 - Early interventional treatment with intranasal mometasone furoate in Japanese cedar/cypress pollinosis: a randomized placebo-controlled trial.
Seiichiro Makihara; Mitsuhiro Okano; Tazuko Fujiwara; Masayo Kimura; Takaya Higaki; Takenori Haruna; Yohei Noda; Kengo Kanai; Shin Kariya; Kazunori Nishizaki
Allergology international : official journal of the Japanese Society of Allergology, Jun. 2012 - Characterization of pollen antigen-induced IL-31 production by PBMCs in patients with allergic rhinitis.
Mitsuhiro Okano; Tazuko Fujiwara; Takaya Higaki; Seiichiro Makihara; Takenori Haruna; Yohei Noda; Kengo Kanai; Shin Kariya; Hiroshi Yasueda; Kazunori Nishizaki
The Journal of allergy and clinical immunology, Jan. 2011 - Prostaglandin E(2) suppresses staphylococcal enterotoxin-induced eosinophilia-associated cellular responses dominantly through an E-prostanoid 2-mediated pathway in nasal polyps.
Mitsuhiro Okano; Tazuko Fujiwara; Takenori Haruna; Shin Kariya; Seiichiro Makihara; Takaya Higaki; Kazunori Nishizaki
The Journal of allergy and clinical immunology, Apr. 2009
MISC
- A Study on 65 Cases of Congenital Aural Fistula Treated by Surgery
佐伯忠彦; 小川晃弘; 春名威範; 黒田一彬
耳鼻咽喉科臨床, 2025 - A Study on 121 Cases with a Foreign Body in the External Auditory Canal, Including a Case of Aural Myiasis
佐伯忠彦; 小川晃弘; 春名威範; 黒田一彬
耳鼻咽喉科臨床, 2025 - Clinical Study of 162 Cases of Peritonsillar Abscess Diagnosed by Contrast-Enhanced Computed Tomography
佐伯忠彦; 小川晃弘; 春名威範; 黒田一彬
耳鼻咽喉科臨床 補冊, 2025 - 好酸球性副鼻腔炎に対してDupilumab投与後に好酸球性多発血管炎性肉芽腫症を発症した一例
春名威範; 小川晃弘; 佐伯忠彦; 檜垣貴哉; 岡野光博
日本耳鼻咽喉科免疫アレルギー感染症学会総会・学術講演会プログラム・抄録集(CD-ROM), 2023 - スギ花粉症に対する鼻噴霧用ステロイド薬への鼻噴霧用抗ヒスタミン薬の上乗せ効果に関する医療経済的評価の検討
春名威範; 岡愛子; 金井健吾; 檜垣貴哉; 牧原靖一郎; 安藤瑞生; 佐伯忠彦; 小川晃弘; 赤松摩紀; 岡野光博; 岡野光博
日本職業・環境アレルギー学会雑誌(Web), 2023 - 花粉症・アレルギー性鼻炎—特集 大きく変わった?ステロイドの使い方 ; 各種疾患におけるステロイドの使い方
岡野 光博; 金井 健吾; 岡 愛子; 春名 威範
臨牀と研究 = The Japanese journal of clinical and experimental medicine, Oct. 2022 - 好酸球性副鼻腔炎における黄色ブドウ球菌エンテロトキシン曝露後のIL-10産生と重症度の関連—Association between the impairment of IL-10 production following exposure to staphylococcal enterotoxin and disease severity in eosinophilic chronic rhinosinusitis—特集 慢性副鼻腔炎up-to-date
岡野 光博; 春名 威範; 小山 貴久
臨床免疫・アレルギー科 = Clinical immunology & allergology / 臨床免疫・アレルギー科編集委員会 編, Apr. 2019 - 鼻噴霧ステロイド薬を用いた初期治療の有効性—Efficacy of prophylactic treatment with nasal corticosteroids—特集 スギ花粉症の発症と初期治療
小山 貴久; 岡野 光博; 春名 威範
臨床免疫・アレルギー科 = Clinical immunology & allergology / 臨床免疫・アレルギー科編集委員会 編, Dec. 2013 - O58-6 黄色ブドウ球菌αトキシンによる鼻茸細胞からのサイトカイン産生(サイトカイン・ケモカイン1,口演,第62回日本アレルギー学会秋季学術大会)
春名 威範; 岡野 光博; 檜垣 貴哉; 西崎 和則
アレルギー, 2012 - 副鼻腔炎の難治化における真菌の役割—Role of fungi in the pathogenesis of intractable chronic rhinosinusitis—特集 難治性アレルギー疾患における真菌の役割
岡野 光博; 木林 並樹; 春名 威範
臨床免疫・アレルギー科 = Clinical immunology & allergology / 臨床免疫・アレルギー科編集委員会 編, Oct. 2008 - アレルギー性真菌性副鼻腔炎--難治性副鼻腔炎における真菌の関与について—特集 アレルギー疾患における真菌の重要性
岡野 光博; 仮谷 伸; 春名 威範
アレルギー・免疫 = Allergology & immunology, Sep. 2008 - S15-4 慢性副鼻腔炎の難治化における真菌の役割(難治性アレルギー疾患における真菌の役割,シンポジウム,第57回日本アレルギー学会秋季学術大会)
岡野 光博; 仮谷 伸; 木林 並樹; 春名 威範
アレルギー, 2007 - 来院前の心肺蘇生が奏効し,その後社会復帰を果たした心肺停止症例3例の検討
春名威範; 内藤宏道; 渡辺めぐみ; 長江正晴; 笠井慎也; 萩岡信吾; 白石建輔; 森本直樹; 杉山雅俊
日本救急医学会雑誌, 2006
Research Themes
- Development of predicting factor for the efficacy of sublingual immunotherapy for Japanese cedar pollinosis using saliva
Grant-in-Aid for Scientific Research (B)
Okayama University
01 Apr. 2015 - 31 Mar. 2019 - Role of Staphylococcus aureus alpha-toxin and IL-22 in the pathogenesis of eosinophilic rhinosinusitis
Grant-in-Aid for Young Scientists (B)
Okayama University
01 Apr. 2013 - 31 Mar. 2016
