Last Updated :2024/12/19
Researcher Information
Research Keyword
Field Of Study
Career
- 2023 - Present
Hyogo Medical University Educational Foundation, Vice Chairman of the Board of Trustees - 2020 - Present
日本痛み関連学会連合代表 - 2016 - 2023
Hyogo College of Medicine, 学長 - 2013 - 2022
日本疼痛学会理事長 - 1994 - 2022
Hyogo College of Medicine, Faculty of Medicine, 教授 - 1991 - 1994
Wakayama Medical University, 助教授 - 1989 - 1991
大阪大学医学部解剖学第二講座, 助手 - 1989 - 1991
National Institute of Health, Visiting Fellow - 1986 - 1989
大阪大学大学院医学研究科博士課程 - 1983 - 1984
大阪大学医学部付属病院研修医
Research activity information
Paper
- Sympathetic Nervous System Overactivation Induces Colonic Eosinophil-Associated Microinflammation and Contributes to the Pathogenesis of Irritable Bowel Syndrome
Shaoqi Duan; Hirosato Kanda; Feng Zhu; Masamichi Okubo; Taro Koike; Yoshiya Ohno; Toshiyuki Tanaka; Yukiko Harima; Kazunari Miyamichi; Hirokazu Fukui; Shinichiro Shinzaki; Yilong Cui; Koichi Noguchi; Yi Dai
Jul. 2024 - COX2 expression plays a role in spinal cord injury-induced neuropathic pain.
Masakazu Toi; Tachibana Toshiya; Koichi Noguchi; Hiroki Yamanaka; Kimiko Kobayashi; Masamichi Okubo; Kazuya Kishima; Yi Dai
Neuroscience letters, Jan. 2024 - 交感神経活動による大腸好酸球浸潤の誘導と内臓知覚過敏への関与(Sympathetic activation-induced colonic eosinophil infiltration contributes to visceral hypersensitivity)
段 韶き; 神田 浩里; 野口 光一; 戴 毅
PAIN RESEARCH, Dec. 2023 - 交感神経活動による大腸好酸球浸潤の誘導と内臓知覚過敏への関与(Sympathetic activation-induced colonic eosinophil infiltration contributes to visceral hypersensitivity)
段 韶き; 神田 浩里; 野口 光一; 戴 毅
PAIN RESEARCH, Dec. 2023 - 脊髄損傷による神経障害性疼痛におけるCOX2の発現に関する研究
都井 政和; 橘 俊哉; 山中 博樹; 小林 希実子; 大久保 正道; 野口 光一
Journal of Spine Research, Apr. 2023 - Axonal membrane stretch suppresses neuronal excitability by activating mechanosensitive K2P channels at the node of Ranvier
Hirosato Kanda; Koichi Noguchi; Yi Dai
Molecular Brain, Jan. 2023, [Reviewed] - 抑肝散はFDモデルラットの胃痛覚過敏と微小炎症を抑制する(Yokukansan suppresses gastric pain hypersensitivity and micro inflammation in FD model rats)
段 韶き; 今村 信子; 近藤 隆; 神田 浩里; 三輪 洋人; 野口 光一; 戴 毅
PAIN RESEARCH, Dec. 2022 - 脊髄損傷による神経障害性疼痛におけるCOX2の発現に関する研究
都井 政和; 橘 俊哉; 野口 光一; 山中 博樹; 小林 希実子; 大久保 正道; 木島 和也; 戴 毅
PAIN RESEARCH, Dec. 2022 - Yokukansan Suppresses Gastric Hypersensitivity and Eosinophil-associated Microinflammation in Rats With Functional Dyspepsia.
Shaoqi Duan; Nobuko Imamura; Takashi Kondo; Hirosato Kanda; Yoko Kogure; Takuya Okugawa; Masashi Fukushima; Toshihiko Tomita; Tadayuki Oshima; Hirokazu Fukui; Koichi Noguchi; Yi Dai; Hiroto Miwa
Journal of neurogastroenterology and motility, Apr. 2022 - Analgesic effect of gastrin-releasing peptide in the dorsal horn.
Ayano Saeki; Hiroki Yamanaka; Kimiko Kobayashi; Masamichi Okubo; Koichi Noguchi
Molecular pain, Apr. 2022 - Reactive Oxygen Species Cause Exercise-Induced Angina in a Myocardial Ischaemia-Reperfusion Injury Model
Xiaohang Wang; Hirosato; Takeshi Tsujino; Yoko Kogure; Feng Zhu; Satoshi Yamamoto; Taichi Sakaguchi; Koichi Noguchi; Yi Dai
International Journal of Molecular Sciences, Mar. 2022 - Acid increases PGE2 in the duodenal mucosa in rats.
Tadahiro Fujimura; Takashi Kondo; Kimiko Kobayashi; Shaoqi Duan; Hirosato Kanda; Tomoaki Kono; Masashi Fukushima; Toshihiko Tomita; Tadayuki Oshima; Hirokazu Fukui; Yoshihito Fujii; Takashi Konemura; Hiroki Okada; Hiroki Yamanaka; Yi Dai; Koichi Noguchi; Hiroto Miwa
Journal of clinical biochemistry and nutrition, Jan. 2022 - 過酸化水素によるTRPA1チャネルの活性化はPCI後狭心症の発症に関与する(The activation of TRPA1 by cardiac hydrogen peroxide is involved in angina after PCI of a rodent model)
王 暁航; 神田 浩里; 坂口 太一; 野口 光一; 戴 毅
PAIN RESEARCH, Dec. 2021 - 過酸化水素によるTRPA1チャネルの活性化はPCI後狭心症の発症に関与する(The activation of TRPA1 by cardiac hydrogen peroxide is involved in angina after PCI of a rodent model)
王 暁航; 神田 浩里; 坂口 太一; 野口 光一; 戴 毅
PAIN RESEARCH, Dec. 2021 - Atractylodin Produces Antinociceptive Effect through a Long-Lasting TRPA1 Channel Activation.
Hirosato Kanda; Yanjing Yang; Shaoqi Duan; Yoko Kogure; Shenglan Wang; Emiko Iwaoka; Miku Ishikawa; Saki Takeda; Hidemi Sonoda; Kyoka Mizuta; Shunji Aoki; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
International journal of molecular sciences, Mar. 2021, [Reviewed] - Kv4.3 Channel Dysfunction Contributes to Trigeminal Neuropathic Pain Manifested with Orofacial Cold Hypersensitivity in Rats.
Hirosato Kanda; Jennifer Ling; Ya-Ting Chang; Ferhat Erol; Viacheslav Viatchenko-Karpinski; Akihiro Yamada; Koichi Noguchi; Jianguo G Gu
The Journal of neuroscience : the official journal of the Society for Neuroscience, Mar. 2021, [Reviewed] - The ubiquitin E3 ligase Nedd4-2 relieves mechanical allodynia through the ubiquitination of TRPA1 channel in db/db mice.
Shenglan Wang; Simin Qi; Yoko Kogure; Hirosato Kanda; Lin Tian; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
The European journal of neuroscience, Mar. 2021, [Reviewed] - Role of Rho-associated coiled-coil containing protein kinase in the spinal cord injury induced neuropathic pain.
Kazuya Kishima; Toshiya Tachibana; Hiroki Yamanaka; Kimiko Kobayashi; Masamichi Okubo; Keishi Maruo; Koichi Noguchi
The spine journal : official journal of the North American Spine Society, Feb. 2021, [Reviewed] - Eosinophil-associated microinflammation in the gastroduodenal tract contributes to gastric hypersensitivity in a rat model of early-life adversity.
Shaoqi Duan; Takashi Kondo; Hiroto Miwa; Yanjing Yang; Shenglan Wang; Hirosato Kanda; Yoko Kogure; Nobuko Imamura; Tadahiro Fujimura; Tomoaki Kono; Masashi Fukushima; Katsuyuki Tozawa; Toshihiko Tomita; Tadayuki Oshima; Hirokazu Fukui; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
American journal of physiology. Gastrointestinal and liver physiology, Feb. 2021, [Reviewed] - Aberrant axo-axonic synaptic reorganization in the phosphorylated l1-cam/calcium channel subunit α2δ 1-containing central terminals of injured c-fibers in the spinal cord of a neuropathic pain model
Hiroki Yamanaka; Masamichi Okubo; Kimiko Kobayashi; Koichi Noguchi
eNeuro, 2021 - Localization of prostaglandin E2 synthases and E-prostanoid receptors in the spinal cord in a rat model of neuropathic pain.
Hirosato Kanda; Kimiko Kobayashi; Hiroki Yamanaka; Masamichi Okubo; Yi Dai; Koichi Noguchi
Brain research, Jan. 2021, [Reviewed] - Daikenchuto attenuates visceral pain and suppresses eosinophil infiltration in inflammatory bowel disease in murine models.
Yoko Kogure; Hirosato Kanda; Shenglan Wang; Yongbiao Hao; Junxiang Li; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
JGH open : an open access journal of gastroenterology and hepatology, Dec. 2020, [Reviewed] - TREK-1 and TRAAK Are Principal K+ Channels at the Nodes of Ranvier for Rapid Action Potential Conduction on Mammalian Myelinated Afferent Nerves.
Kanda H; Ling J; Tonomura S; Noguchi K; Matalon S; Gu JG
Neuron, Sep. 2019, [Reviewed] - TRPA1-expressing lamina propria mesenchymal cells regulate colonic motility.
Yang Y; Wang S; Kobayashi K; Hao Y; Kanda H; Kondo T; Kogure Y; Yamanaka H; Yamamoto S; Li J; Miwa H; Noguchi K; Dai Y
JCI insight, May 2019, [Reviewed] - Spinal glial cell line-derived neurotrophic factor infusion reverses reduction of Kv4.1-mediated A-type potassium currents of injured myelinated primary afferent neurons in a neuropathic pain model
Masamichi Shinoda; Tetsuo Fukuoka; Mamoru Takeda; Koichi Iwata; Koichi Noguchi
Molecular Pain, Apr. 2019, [Reviewed] - Differential expression of mGluRs in rat spinal dorsal horns and their modulatory effects on nocifensive behaviors
Masamichi Okubo; Hiroki Yamanaka; Kimiko Kobayashi; Koichi Noguchi
Molecular Pain, Jan. 2019, [Reviewed] - Pain matrix shift in the rat brain following persistent colonic inflammation revealed by voxel-based statistical analysis
Tianliang Huang; Takashi Okauchi; Di Hu; Mika Shigeta; Yuping Wu; Yasuhiro Wada; Emi Hayashinaka; Shenglan Wang; Yoko Kogure; Koichi Noguchi; Yasuyoshi Watanabe; Yi Dai; Yilong Cui
Molecular Pain, 2019 - Recombinant interleukin-4 alleviates mechanical allodynia via injury-induced interleukin-4 receptor alpha in spinal microglia in a rat model of neuropathic pain.
Okutani H; Yamanaka H; Kobayashi K; Okubo M; Noguchi K
Glia, Aug. 2018, [Reviewed] - Upregulation of calcium channel alpha-2-delta-1 subunit in dorsal horn contributes to spinal cord injury-induced tactile allodynia
Kazuki Kusuyama; Toshiya Tachibana; Hiroki Yamanaka; Masamichi Okubo; Shinichi Yoshiya; Koichi Noguchi
Spine Journal, Jun. 2018, [Reviewed] - Negative regulation of TRPA1 by AMPK in primary sensory neurons as a potential mechanism of painful diabetic neuropathy
Shenglan Wang; Kimiko Kobayashi; Yoko Kogure; Hiroki Yamanaka; Satoshi Yamamoto; Hideshi Yagi; Koichi Noguchi; Yi Dai
Diabetes, Jan. 2018, [Reviewed] - Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor
Syuhei Nakao; Miyuki Mabuchi; Shenglan Wang; Yoko Kogure; Tadashi Shimizu; Koichi Noguchi; Akito Tanaka; Yi Dai
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Jul. 2017, [Reviewed] - Interleukin-18 and its receptor are expressed in gonadotropin-releasing hormone neurons of mouse and rat forebrain
Sachi Kuwahara-Otani; Seishi Maeda; Kimiko Kobayashi; Yusuke Minato; Koichi Tanaka; Kyosuke Yamanishi; Masaki Hata; Wen Li; Tetsu Hayakawa; Koichi Noguchi; Haruki Okamura; Hideshi Yagi
NEUROSCIENCE LETTERS, May 2017, [Reviewed] - Microglial TNFα induces COX2 and PGI2 synthase expression in spinal endothelial cells during neuropathic pain
Hirosato Kanda; Kimiko Kobayashi; Hiroki Yamanaka; Masamichi Okubo; Koichi Noguchi
eNeuro, 2017, [Reviewed] - Correlation Between DNA Methylation of TRPA1 and Chronic Pain States in Human Whole Blood Cells
Norihiko Sukenaga; Yasuko Ikeda-Miyagawa; Daisuke Tanada; Takashi Tunetoh; Susumu Nakano; Takae Inui; Kazumi Satoh; Hiroai Okutani; Koichi Noguchi; Munetaka Hirose
PAIN MEDICINE, Oct. 2016, [Reviewed] - Fibromyalgia and Chronic Pain Syndromes: A White Paper Detailing Current Challenges in the Field.
Lesley M Arnold; Ernest Choy; Daniel J Clauw; Don L Goldenberg; Richard E Harris; Milton Helfenstein Jr; Troels Staehelin Jensen; Koichi Noguchi; Stuart L Silverman; Takahiro Ushida; Guochun Wang
The Clinical journal of pain, Sep. 2016, [Reviewed] - Elevated H2O2 levels in trinitrobenzene sulfate-induced colitis rats contributes to visceral hyperalgesia through interaction with the transient receptor potential ankyrin 1 cation channel
Yoko Kogure; Shenglan Wang; Koh-ichi Tanaka; Yongbiao Hao; Satoshi Yamamoto; Nobuyoshi Nishiyama; Koichi Noguchi; Yi Dai
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Jun. 2016, [Reviewed] - Partial Activation and Inhibition of TRPV1 Channels by Evodiamine and Rutaecarpine, Two Major Components of the Fruits of Evodia rutaecarpa
Shenglan Wang; Satoshi Yamamoto; Yoko Kogure; Wensheng Zhang; Koichi Noguchi; Yi Dai
JOURNAL OF NATURAL PRODUCTS, May 2016, [Reviewed] - Macrophage-Colony Stimulating Factor Derived from Injured Primary Afferent Induces Proliferation of Spinal Microglia and Neuropathic Pain in Rats
Masamichi Okubo; Hiroki Yamanaka; Kimiko Kobayashi; Yi Dai; Hirosato Kanda; Hideshi Yagi; Koichi Noguchi
PLOS ONE, Apr. 2016, [Reviewed] - Filamin A interacting protein plays a role in proper positioning of callosal projection neurons in the cortex
Hideshi Yagi; Yuichiro Oka; Munekazu Komada; Min-Jue Xie; Koichi Noguchi; Makoto Sato
Neuroscience Letters, Jan. 2016, [Reviewed] - Evodiamine suppresses capsaicin-induced thermal hyperalgesia through activation and subsequent desensitization of the transient receptor potential V1 channels
Emiko Iwaoka; Shenglan Wang; Nobuyuki Matsuyoshi; Yoko Kogure; Shunji Aoki; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
JOURNAL OF NATURAL MEDICINES, Jan. 2016, [Reviewed] - Filamin A interacting protein plays a role for proper positioning of callosal projection neurons in the cortex.
Yagi, H; Oka, Y; Komada, M; Xie, M.J; Noguchi, K; Sato, M
Neuroscience Letters, Jan. 2016, [Reviewed] - Annexin A2 in primary afferents contributes to neuropathic pain associated with tissue type plasminogen activator
Yamanaka H; Kobayashi K; Okubo M; Noguchi K
Neuroscience, 2016, [Reviewed] - Changes in transient receptor potential channels in the rat geniculate ganglion after chorda tympani nerve injury
Emiko Tatsumi; Hirokazu Katsura; Kimiko Kobayashi; Hiroki Yamanaka; Kenzo Tsuzuki; Koichi Noguchi; Masafumi Sakagami
NEUROREPORT, Sep. 2015, [Reviewed] - Leukotriene enhances NMDA-induced inward currents in dorsal horn neurons of the rat spinal cord after peripheral nerve injury
Yasukuni Kiyoyuki; Wataru Taniguchi; Masamichi Okubo; Hiroki Yamanaka; Kimiko Kobayashi; Naoko Nishio; Terumasa Nakatsuka; Koichi Noguchi
MOLECULAR PAIN, Sep. 2015, [Reviewed] - A POTENTIAL ANTI-ALLODYNIC MECHANISM OF GDNF FOLLOWING L5 SPINAL NERVE LIGATION; MITIGATION OF NPY UP-REGULATION IN THE TOUCH SENSE PATHWAY
T. Fukuoka; K. Noguchi
NEUROSCIENCE, Sep. 2015, [Reviewed] - Peripherally increased artemin is a key regulator of TRPA1/V1 expression in primary afferent neurons
Yasuko Ikeda-Miyagawa; Kimiko Kobayashi; Hiroki Yamanaka; Masamichi Okubo; Shenglan Wang; Yi Dai; Hideshi Yagi; Munetaka Hirose; Koichi Noguchi
MOLECULAR PAIN, Mar. 2015, [Reviewed] - RhoA/ROCK Pathway Mediates p38 MAPK Activation and Morphological Changes Downstream of P2Y12/13 Receptors in Spinal Microglia in Neuropathic Pain
Emiko Tatsumi; Hiroki Yamanaka; Kimiko Kobayashi; Hideshi Yagi; Masafumi Sakagami; Koichi Noguchi
GLIA, Feb. 2015, [Reviewed] - 周産期における中枢性化学受容の低酸素とTRPA1チャネルの反応性について
志賀 真理; 小林 希実子; 下村 英毅; 野口 光一; 荒田 晶子
日本生理学雑誌, Jan. 2015 - DE NOVO EXPRESSION OF NAV1.7 IN INJURED PUTATIVE PROPRIOCEPTIVE AFFERENTS: MULTIPLE TETRODOTOXIN-SENSITIVE SODIUM CHANNELS ARE RETAINED IN THE RAT DORSAL ROOT AFTER SPINAL NERVE LIGATION
T. Fukuoka; K. Miyoshi; K. Noguchi
NEUROSCIENCE, Jan. 2015, [Reviewed] - Filamin A-interacting protein (FILIP) is a region-specific modulator of myosin 2b and controls spine morphology and NMDA receptor accumulation
Hideshi Yagi; Takashi Nagano; Min-Jue Xie; Hiroshi Ikeda; Kazuki Kuroda; Munekazu Komada; Tokuichi Iguchi; Rahman M. Tariqur; Soichi Morikubo; Koichi Noguchi; Kazuyuki Murase; Masaru Okabe; Makoto Sato
SCIENTIFIC REPORTS, Sep. 2014, [Reviewed] - Spinal 5-HT3 receptors mediate descending facilitation and contribute to behavioral hypersensitivity via a reciprocal neuron-glial signaling cascade
Wei Guo; Kan Miyoshi; Ronald Dubner; Ming Gu; Man Li; Jian Liu; Jiale Yang; Shiping Zou; Ke Ren; Koichi Noguchi; Feng Wei
MOLECULAR PAIN, Jun. 2014, [Reviewed] - TNBS誘発性大腸炎モデルラットの内臓痛発症メカニズムにおける過酸化水素の役割
小暮 洋子; 王 勝蘭; 田中 康一; 山本 悟史; 西山 信好; 野口 光一; 戴 毅
日本薬学会年会要旨集, Mar. 2014 - Xilei San Ameliorates Experimental Colitis in Rats by Selectively Degrading Proinflammatory Mediators and Promoting Mucosal Repair
Yongbiao Hao; Kazuko Nagase; Kazutoshi Hori; Shenglan Wang; Yoko Kogure; Ken Fukunaga; Shinichiro Kashiwamura; Satoshi Yamamoto; Shiro Nakamura; Junxiang Li; Hiroto Miwa; Koichi Noguchi; Yi Dai
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2014, [Reviewed] - Etodolac Activates and Desensitizes Transient Receptor Potential Ankyrin 1
Shenglan Wang; Yi Dai; Yoko Kogure; Satoshi Yamamoto; Wensheng Zhang; Koichi Noguchi
JOURNAL OF NEUROSCIENCE RESEARCH, Dec. 2013, [Reviewed] - Transient receptor potential channel A1 involved in calcitonin gene-related peptide release in neurons
Nobumasa Ushio; Yi Dai; Shenglan Wang; Tetsuo Fukuoka; Koichi Noguchi
Neural Regeneration Research, Nov. 2013, [Reviewed] - COX-1-dependent prostaglandin D2 in microglia contributes to neuropathic pain via DP2 receptor in spinal neurons
Hirosato Kanda; Kimiko Kobayashi; Hiroki Yamanaka; Koichi Noguchi
GLIA, Jun. 2013, [Reviewed] - Upregulated glial cell line-derived neurotrophic factor through cyclooxygenase-2 activation in the muscle is required for mechanical hyperalgesia after exercise in rats
Shiori Murase; Etsuji Terazawa; Kenji Hirate; Hiroki Yamanaka; Hirosato Kanda; Koichi Noguchi; Hiroki Ota; Fernando Queme; Toru Taguchi; Kazue Mizumura
Journal of Physiology, Jun. 2013, [Reviewed] - Phosphorylation of ezrin/radixin/moesin (ERM) protein in spinal microglia following peripheral nerve injury and lysophosphatidic acid administration
Ryosuke Kashimoto; Hiroki Yamanaka; Kimiko Kobayashi; Masamichi Okubo; Hideshi Yagi; Osamu Mimura; Koichi Noguchi
GLIA, Mar. 2013, [Reviewed] - Modulation of TRP channels by resveratrol and other stilbenoids
Lina Yu; Shenglan Wang; Yoko Kogure; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
MOLECULAR PAIN, Feb. 2013, [Reviewed] - Expression of ATP receptors in the rat dorsal root ganglion and spinal cord
Kimiko Kobayashi; Hiroki Yamanaka; Koichi Noguchi
ANATOMICAL SCIENCE INTERNATIONAL, Jan. 2013, [Reviewed] - Activation of p38 MAPK through transient receptor potential A1 in a rat model of gastric distension-induced visceral pain
Takashi Kondo; Jun Sakurai; Hiroto Miwa; Koichi Noguchi
NEUROREPORT, Jan. 2013, [Reviewed] - Involvement of TRPA 1 channel in the respiratory rhythm in the hypoxia during perinatal period
Mari Shiga; Kimiko Kobayashi; Hideki Shimomura; Takakuni Tanizawa; Koichi Noguchi; Akiko Arata
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2013 - Spatio-temporal imaging of spinal activities in the rat model of pain hypersensitivity
Kan Miyoshi; Tetsuo Fukuoka; Koichi Noguchi
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013 - Etodolac activates and desensitizes transient receptor potential ankyrin 1 through cysteine modification
Shenglan Wang; Koichi Noguchi; Yi Dai
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013 - Spinal 5-HT3 Receptor Activation Induces Behavioral Hypersensitivity via a Neuronal-Glial-Neuronal Signaling Cascade (Retraction of September, pg 12823, 2011)
Ming Gu; Kan Miyoshi; Ronald Dubner; Wei Guo; Shiping Zou; Ke Ren; Koichi Noguchi; Feng Wei
JOURNAL OF NEUROSCIENCE, Dec. 2012 - Pathophysiology of neuropathic pain: Molecular mechanisms underlying central sensitization in the dorsal horn in neuropathic pain
Hiroki Yamanaka; Koichi Noguchi
Brain and Nerve, Nov. 2012, [Reviewed] - Multiple P2Y subtypes in spinal microglia are involved in neuropathic pain after peripheral nerve injury
Kimiko Kobayashi; Hiroki Yamanaka; Fujio Yanamoto; Masamichi Okubo; Koichi Noguchi
GLIA, Oct. 2012, [Reviewed] - An ultrastructural evidence for the expression of transient receptor potential ankyrin 1 (TRPA1) in astrocytes in the rat trigeminal caudal nucleus
Sang Man Lee; Yi Sul Cho; Tae Fleon Kim; Myoung Uk Jin; Dong Kuk Ahn; Koichi Noguchi; Yong Chul Bae
JOURNAL OF CHEMICAL NEUROANATOMY, Oct. 2012, [Reviewed] - Increased expression of interleukin-18 in the trigeminal spinal subnucleus caudalis after inferior alveolar nerve injury in the rat
Erina Daigo; Yasushi Sakuma; Kan Miyoshi; Koichi Noguchi; Junichiro Kotani
NEUROSCIENCE LETTERS, Oct. 2012, [Reviewed] - Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain
Shenglan Wang; Yi Dai; Kimiko Kobayashi; Wanjun Zhu; Yoko Kogure; Hiroki Yamanaka; You Wan; Wensheng Zhang; Koichi Noguchi
EUROPEAN JOURNAL OF NEUROSCIENCE, Aug. 2012, [Reviewed] - Up-regulation of platelet-activating factor synthases and its receptor in spinal cord contribute to development of neuropathic pain following peripheral nerve injury
Masamichi Okubo; Hiroki Yamanaka; Kimiko Kobayashi; Hirosato Kanda; Yi Dai; Koichi Noguchi
MOLECULAR PAIN, Feb. 2012, [Reviewed] - Re-evaluation of the phenotypic changes in L4 dorsal root ganglion neurons after L5 spinal nerve ligation
Tetsuo Fukuoka; Hiroki Yamanaka; Kimiko Kobayashi; Masamichi Okubo; Kan Miyoshi; Yi Dai; Koichi Noguchi
PAIN, Jan. 2012, [Reviewed] - Evodiamine activates TRPV1 in primary sensory neurons
Emiko Iwaoka; Nobuyuki Matsuyoshi; Yoko Kogure; Shunji Aoki; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012 - Induction of the P2X7 receptor in spinal microglia in a neuropathic pain model
Kimiko Kobayashi; Emiko Takahashi; Yasuko Miyagawa; Hiroki Yamanaka; Koichi Noguchi
NEUROSCIENCE LETTERS, Oct. 2011, [Reviewed] - Spinal 5-HT3 Receptor Activation Induces Behavioral Hypersensitivity via a Neuronal-Glial-Neuronal Signaling Cascade (Retracted article. See vol. 32, pg. 18270, 2012)
Ming Gu; Kan Miyoshi; Ronald Dubner; Wei Guo; Shiping Zou; Ke Ren; Koichi Noguchi; Feng Wei
JOURNAL OF NEUROSCIENCE, Sep. 2011, [Reviewed] - Leukotrienes in Nociceptive Pathway and Neuropathic/Inflammatory Pain
Koichi Noguchi; Masamichi Okubo
BIOLOGICAL & PHARMACEUTICAL BULLETIN, Aug. 2011, [Reviewed] - ゴシュユの主成分エボジアミンによる一次知覚ニューロンの活性化
岩岡 恵実子; 松吉 延之; 小暮 洋子; 青木 俊二; 野口 光一; 戴 毅
Journal of Traditional Medicines, Aug. 2011 - Comparative study of voltage-gated sodium channel alpha-subunits in non-overlapping four neuronal populations in the rat dorsal root ganglion
Tetsuo Fukuoka; Koichi Noguchi
NEUROSCIENCE RESEARCH, Jun. 2011, [Reviewed] - Increase of Close Homolog of Cell Adhesion Molecule L1 in Primary Afferent by Nerve Injury and the Contribution to Neuropathic Pain
Hiroki Yamanaka; Kimiko Kobayashi; Masamichi Okubo; Tetsuo Fukuoka; Koichi Noguchi
JOURNAL OF COMPARATIVE NEUROLOGY, Jun. 2011, [Reviewed] - Inhibition of TRPA1 channel activity in sensory neurons by the glial cell line-derived neurotrophic factor family member, artemin
Naoki Yoshida; Kimiko Kobayashi; Lina Yu; Shenglan Wang; Rengaowa Na; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
MOLECULAR PAIN, May 2011, [Reviewed] - Expression of COX1, COX2, PGD(2) and thromboxane A(2) synthases mRNAs in spinal cord following peripheral nerve injury
Hirosato Kanda; Kimiko Kobayashi; Hiroki Yamanaka; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2011 - Activation of TRPA1 and p38 MAPK Mediates Gastric Distention-Induced Visceral Pain in Rats
Takashi Kondo; Tadayuki Oshima; Koichi Obata; Jun Sakurai; Takayuki Matsumoto; Koichi Noguchi; Hiroto Miwa
DIGESTIVE DISEASES AND SCIENCES, Oct. 2010 - Expression of leukotriene receptors in the rat dorsal root ganglion and the effects on pain behaviors
Masamichi Okubo; Hiroki Yamanaka; Kimiko Kobayashi; Tetsuo Fukuoka; Yi Dai; Koichi Noguchi
MOLECULAR PAIN, Sep. 2010, [Reviewed] - LAMINAE-SPECIFIC DISTRIBUTION OF ALPHA-SUBUNITS OF VOLTAGE-GATED SODIUM CHANNELS IN THE ADULT RAT SPINAL CORD
T. Fukuoka; K. Kobayashi; K. Noguchi
NEUROSCIENCE, Sep. 2010, [Reviewed] - Leukotriene Synthases and the Receptors Induced by Peripheral Nerve Injury in the Spinal Cord Contribute to the Generation of Neuropathic Pain
Masamichi Okubo; Hiroki Yamanaka; Kimiko Kobayashi; Koichi Noguchi
GLIA, Apr. 2010, [Reviewed] - Expression of Transient Receptor Potential Ankyrin 1 (TRPA1) in the Rat Trigeminal Sensory Afferents and Spinal Dorsal Horn
Yun Sook Kim; Jae Youn Son; Tae Heon Kim; Sang Kyoo Paik; Yi Dai; Koichi Noguchi; Dong Kuk Ahn; Yong Chul Bae
JOURNAL OF COMPARATIVE NEUROLOGY, Mar. 2010, [Reviewed] - Role of Transient Receptor Potential A1 in Gastric Nociception
Takashi Kondo; Tadayuki Oshima; Koichi Obata; Jun Sakurai; Charles H. Knowle; Takayuki Matsumoto; Koichi Noguchi; Hiroto Miwa
DIGESTION, 2010, [Reviewed] - Caspase-1 upregulation in spinal glial cells contributes to tactile allodynia after nerve injury
Kan Miyoshi; Koichi Noguchi
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010 - TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury (vol 115, pg 2393, 2005)
Koichi Obata; Hirokazu Katsura; Toshiyuki Mizushima; Hiroki Yamanaka; Kimiko Kobayashi; Yi Dai; Tetsuo Fukuoka; Atsushi Tokunaga; Makoto Tominaga; Koichi Noguchi
JOURNAL OF CLINICAL INVESTIGATION, Jan. 2010 - Transient receptor potential A1 mediates gastric distention-induced visceral pain in rats
T. Kondo; K. Obata; K. Miyoshi; J. Sakurai; J. Tanaka; H. Miwa; K. Noguchi
GUT, Oct. 2009, [Reviewed] - Suppression of the p75 Neurotrophin Receptor in Uninjured Sensory Neurons Reduces Neuropathic Pain after Nerve Injury (vol 26, pg 11974, 2006)
Koichi Obata; Hirokazu Katsura; Jun Sakurai; Kimiko Kobayashi; Hiroki Yamanaka; Yi Dai; Tetsuo Fukuoka; Koichi Noguchi
JOURNAL OF NEUROSCIENCE, Oct. 2009 - Taste disturbance after stapes surgery--clinical and experimental study.
Miuchi S; Sakagami M; Tsuzuki K; Noguchi K; Mishiro Y; Katsura H
Acta oto-laryngologica. Supplementum, Jun. 2009, [Reviewed] - 3P-192 Induction of P2Y receptors in the spinal cord following peripheral nerve injury.(Neuroscience & Sensory systems,The 47th Annual Meeting of the Biophysical Society of Japan)
Kobayashi Kimiko; Yamanaka Hiroki; Noguchi Koichi
Seibutsu Butsuri, 2009 - Expression and phosphorylation of ERM family proteins in rat spinal dorsal horn with spared nerve injury (SNI) model
Ryosuke Kashimoto; Hiroki Yamanaka; Kimiko Kobayashi; Masamichi Okubo; Osamu Mimura; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2009 - Activation of RET in uninjured primary sensory neurons contributes to the development of pain hypersensitivity after nerve injury
Koichi Obata; Kan Miyoshi; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2009 - IL-18-mediated microglia/astrocyte interaction in the spinal cord enhances neuropathic pain processing after nerve injury
Kan Miyoshi; Koichi Obata; Koichi Noguchi
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009 - Platelet-activating factor biosynthesis in spinal cord contributes to neuropathic pain following peripheral nerve injury
Masamichi Okubo; Hiroki Yamanaka; Kimiko Kobayashi; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2009 - Induction of P2 receptors in the spinal microglia following peripheral nerve injury
Kimiko Kobayashi; Hiroki Yamanaka; Masamichi Okubo; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2009 - Interleukin-1 beta converting enzyme (ICE) upregulation in spinal glial cells contributes to tactile allodynia after nerve injury
Kan Miyoshi; Koichi Obata; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2009 - Taste disturbance after stapes surgery - clinical and experimental study
Shinya Miuchi; Masafumi Sakagami; Kenzo Tsuzuki; Koichi Noguchi; Yasuo Mishiro; Hirokazu Katsura
ACTA OTO-LARYNGOLOGICA, 2009, [Reviewed] - Interleukin-18-Mediated Microglia/Astrocyte Interaction in the Spinal Cord Enhances Neuropathic Pain Processing after Nerve Injury
Kan Miyoshi; Koichi Obata; Takashi Kondo; Haruki Okamura; Koichi Noguchi
JOURNAL OF NEUROSCIENCE, Nov. 2008, [Reviewed] - [Intensity-dependent activation of extracellular signal-regulated protein kinases (ERK) 5 in sensory neurons contributes to pain hypersensitivity].
Mizushima T; Obata K; Noguchi K; Mashimo T
Masui. The Japanese journal of anesthesiology, Nov. 2008, [Reviewed] - Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons
Tetsuo Fukuoka; Kimiko Kobayashi; Hiroki Yamanaka; Koichi Obata; Yi Dai; Koichi Noguchi
JOURNAL OF COMPARATIVE NEUROLOGY, Sep. 2008, [Reviewed] - Toll-like receptor 3 contributes to spinal glial activation and tactile allodynia after nerve injury
K. Obata; H. Katsura; K. Miyoshi; T. Kondo; H. Yamanaka; K. Kobayashi; Y. Dai; T. Fukuoka; S. Akira; K. Noguchi
JOURNAL OF NEUROCHEMISTRY, Jun. 2008, [Reviewed] - Transforming growth factor-activated kinase 1 induced in spinal astrocytes contributes to mechanical hypersensitivity after nerve injury
Hirokazu Katsura; Koichi Obata; Kan Miyoshi; Takashi Kondo; Hiroki Yamanaka; Kimiko Kobayashi; Yi Dai; Tetsuo Fukuoka; Masafumi Sakagami; Koichi Noguchi
GLIA, May 2008, [Reviewed] - Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain
Shenglan Wang; Yi Dai; Tetsuo Fukuoka; Hiroki Yamanaka; Kimiko Kobayashi; Koichi Obata; Xiuyu Cui; Makoto Tominaga; Koichi Noguchi
BRAIN, May 2008, [Reviewed] - [Contribution of primary sensory neurons and spinal glial cells to pathomechanisms of neuropathic pain]
Obata K; Noguchi K
Brain and nerve = Shinkei kenkyu no shinpo, May 2008, [Reviewed] - Contribution of the primary sensory neurons and spinal glial cells to the pathomechanisms of neuropathic pain
Koichi Obata; Koichi Noguchi
Brain and Nerve, May 2008 - Activation of extracellular signal-regulated protein kinase in sensory neurons after noxious gastric distention and its involvement in acute visceral pain in rats
Jun Sakurai; Koichi Obata; Noriyuki Ozako; Atsushi Tokunaga; Kimiko Kobayashi; Hiroki Yamanaka; Yi Dai; Takashi Kondo; Kan Miyoshi; Yasuo Sugiura; Takayuki Matsumoto; Hiroto Miwa; Koichi Noguchi
GASTROENTEROLOGY, Apr. 2008, [Reviewed] - Differential activation of p38 and extracellular signal-regulated kinase in spinal cord in a model of bee venom-induced inflammation and hyperalgesia
Xiu-Yu Cui; Yi Dai; Sheng-Lan Wang; Hiroki Yamanaka; Kimiko Kobayashi; Koichi Obata; Jun Chen; Koichi Noguchi
MOLECULAR PAIN, Apr. 2008, [Reviewed] - Activation of ERK in sensory neurons after noxious gastric distension and its involvement in acute visceral pain in rat
Jun Sakurai; Koichi Obata; Takashi Kondo; Tadayuki Oshima; Toshihiko Tomita; Takayuki Matsumoto; Koichi Noguchi; Hiroto Miwa
GASTROENTEROLOGY, Apr. 2008 - P2Y(12) receptor Upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain
Kimiko Kobayashi; Hiroki Yamanaka; Tetsuo Fukuoka; Yi Dai; Koichi Obata; Koichi Noguchi
JOURNAL OF NEUROSCIENCE, Mar. 2008, [Reviewed] - IL-18-mediated microglia/astrocyte interaction in the spinal cord enhances neuropathic pain processing after nerve injury
Kan Miyoshi; Koichi Obata; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2008 - Expression of leukotriene synthases and leukotriene receptors in the skin and dorsal root ganglion
Masamichi Okubo; Yamanaka Hiroki; Kobayashi Kimiko; Noguchi Koichi
NEUROSCIENCE RESEARCH, 2008 - TRPA1 mediates gastric distension-induced visceral pain in rats
Takashi Kondo; Koichi Obata; Hiroto Miwa; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2008 - Activation of fibroblast growth factor receptor by axotomy, through downstream p38 in dorsal root ganglion, contributes to neuropathic pain.
Yamanaka H; Obata K; Kobayashi K; Dai Y; Fukuoka T; Noguchi K
Neuroscience, Nov. 2007, [Reviewed] - Sensitization of TRPAl by PAR2 contributes to the sensation of inflammatory pain (vol 117, pg 1979, 2007)
Yi Dai; Shenglan Wang; Makoto Tominaga; Satoshi Yamamoto; Tetsuo Fukuoka; Tomohiro Higashi; Kimiko Kobayashi; Koichi Obata; Hiroki Yamanaka; Koichi Noguchi
JOURNAL OF CLINICAL INVESTIGATION, Oct. 2007 - Roles of extracellular signal-regulated protein kinases 5 in spinal microglia and primary sensory neurons for neuropathic pain
Koichi Obata; Hirokazu Katsura; Toshiyuki Mizushima; Jun Sakurai; Kimiko Kobayashi; Hiroki Yamanaka; Yi Dai; Tetsuo Fukuoka; Koichi Noguchi
JOURNAL OF NEUROCHEMISTRY, Sep. 2007, [Reviewed] - Activation of extracellular signal-regulated protein kinases 5 in primary afferent neurons contributes to heat and cold hyperalgesia after inflammation
Hirokazu Katsura; Koichi Obata; Toshiyuki Mizushima; Jun Sakurai; Kimiko Kobayashi; Hiroki Yamanaka; Yi Dai; Tetsuo Fukuoka; Masafumi Sakagami; Koichi Noguchi
JOURNAL OF NEUROCHEMISTRY, Sep. 2007, [Reviewed] - Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain
Yi Dai; Shenglan Wang; Makoto Tominaga; Satoshi Yamamoto; Tetsuo Fukuoka; Tomohiro Higashi; Kimiko Kobayashi; Koichi Obata; Hiroki Yamanaka; Koichi Noguchi
JOURNAL OF CLINICAL INVESTIGATION, Jul. 2007, [Reviewed] - Frequency-dependent ERK phosphorylation in spinal neurons by electric stimulation of the sciatic nerve and the role in electrophysiological activity
Tomokazu Fukui; Yi Dai; Koichi Iwata; Hiroshi Kamo; Hiroki Yamanaka; Koichi Obata; Kimiko Kobayashi; Shenglan Wang; Xiuyu Cui; Shinichi Yoshiya; Koichi Noguchi
MOLECULAR PAIN, Jul. 2007, [Reviewed] - Intensity-dependent activation of extracellular signal-regulated protein kinase 5 in sensory neurons contributes to pain hypersensitivity
Toshiyuki Mizushima; Koichi Obata; Hirokazu Katsura; Jun Sakurai; Kimiko Kobayashi; Hiroki Yamanaka; Yi Dai; Tetsuo Fukuoka; Takashi Mashimo; Koichi Noguchi
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Apr. 2007, [Reviewed] - Tissue type plasminogen activator induced in rat dorsal horn astrocytes contributes to mechanical hypersensitivity following dorsal root injury
Toyoko Kozai; Hiroki Yamanaka; Yi Dai; Koichi Obata; Kimiko Kobayashi; Takashi Mashimo; Koichi Noguchi
GLIA, Apr. 2007, [Reviewed] - Two types of GABAergic miniature inhibitory postsynaptic currents in mouse substantia gelatinosa neurons (vol 553, pg 120, 2006)
Ayako Takahashi; Atsushi Tokunaga; Hiroki Yamanaka; Takashi Mashimo; Koichi Noguchi; Ichiro Uchida
EUROPEAN JOURNAL OF PHARMACOLOGY, Apr. 2007 - ラット後根神経節・脊髄におけるAdenosine受容体mRNAの発現と坐骨神経切断後の変化
小林 希実子; 福岡 哲男; 山中 博樹; 野口 光一
解剖学雑誌, Mar. 2007 - 末梢神経損傷後の接着因子L1-CAMの発現変化と神経因性疼痛への関与
山中 博樹; 野口 光一
解剖学雑誌, Mar. 2007 - Alteration of the cell adhesion molecule L1 expression in a specific subset of primary afferent neurons contributes to neuropathic pain
Hiroki Yamanaka; Koichi Obata; Kimiko Kobayashi; Yi Dai; Tetsuo Fukuoka; Koichi Noguchi
EUROPEAN JOURNAL OF NEUROSCIENCE, Feb. 2007, [Reviewed] - Axotomy increases plasma membrane Ca2+PUMP isoform4 in primary afferent neurons
Hiroyuki Ogura; Toshiya Tachibana; Hiroki Yamanaka; Kimiko Kobayash; Koichi Obata; Yi Dai; Shinichi Yoshiya; Koichi Noguchi
NEUROREPORT, Jan. 2007, [Reviewed] - Alteration of the cell adhesion molecule CHL1 expression in a specific subset of primary afferent neurons and dorsal horn following nerve injury
Hiroki Yamanaka; Masamichi Okubo; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2007 - Potentiation of TRPA1 activity by Bradykinin
Shenglan Wang; Yi Dai; Makoto Tominaga; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2007 - P2Y12 receptor expressed in spinal microglia contributes to neuropathic pain
Kimiko Kobayashi; Tetsuo Fukuoka; Hiroki Yamanaka; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2007 - Sensitization of TRPA1 by PAR-2 through PLC/PIP2-dependent mechanisms
Yi Dai; Shenglan Wang; Makoto Tominaga; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2007 - TAK1 upregulation in spinal astrocytes contributes to tactile allodynia after nerve injury
Hirokazu Katsura; Koichi Obata; masafumi Sakagami; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2007 - Molecular changes in DRG and spinal cord in the model of neuropathic pain
Koichi Noguchi
NEUROSCIENCE RESEARCH, 2007 - Two types of GABAergic miniature inhibitory postsynaptic currents in mouse substantia gelatinosa neurons
Ayako Takahashi; Atsushi Tokunaga; Hiroki Yamanaka; Takashi Mashimo; Koichi Noguchi; Ichiro Uchida
EUROPEAN JOURNAL OF PHARMACOLOGY, Dec. 2006, [Reviewed] - Suppression of the p75 neurotrophin receptor in uninjured sensory neurons reduces neuropathic pain after nerve injury
Koichi Obata; Hirokazu Katsura; Jun Sakurai; Kimiko Kobayashi; Hiroki Yamanaka; Yi Dai; Tetsuo Fukuoka; Koichi Noguchi
JOURNAL OF NEUROSCIENCE, Nov. 2006, [Reviewed] - Neurons and glial cells differentially express P2Y receptor mRNAs in the rat dorsal root ganglion and spinal cord. (vol 498. pg 443, 2006)
Kimiko Kobayashi; Tetsuo Fukuoka; Hiroki Yamanaka; Yi Dai; Koichi Obata; Atsushi Tokunaga; Koichi Noguchi
JOURNAL OF COMPARATIVE NEUROLOGY, Nov. 2006 - Neurons and glial cells differentially express P2Y receptor mRNAs in the rat dorsal root ganglion and spinal cord
Kimiko Kobayashi; Tetsuo Fukuoka; Hirok Iyamanaka; Yi Dai; Koichi Obata; Atsushi Tokunaga; Koichi Noguchi
JOURNAL OF COMPARATIVE NEUROLOGY, Oct. 2006, [Reviewed] - Differential expression of capsaicin-, menthol-, and mustard oil-sensitive receptors in naive rat geniculate ganglion neurons
Hirokazu Katsura; Kenzo Tsuzuki; Koichi Noguchi; Masafumi Sakagami
CHEMICAL SENSES, Sep. 2006, [Reviewed] - Activation of Src-family kinases in spinal microglia contributes to mechanical hypersensitivity after nerve injury
Hirokazu Katsura; Koichi Obata; Toshiyuki Mizushima; Jun Sakurai; Kimiko Kobayashi; Hiroki Yamanaka; Yi Dai; Tetsuo Fukuoka; Masafumi Sakagami; Koichi Noguchi
JOURNAL OF NEUROSCIENCE, Aug. 2006, [Reviewed] - Agonist of proteinase-activated receptor 2 increases painful behavior produced by alpha, beta-methylene adenosine 5 '-triphosphate
Wan-Jun Zhu; Yi Dai; Tetsuo Fukuoka; Hiroki Yamanaka; Kimiko Kobayashi; Koichi Obata; Shenglan Wang; Koichi Noguchi
NEUROREPORT, Aug. 2006, [Reviewed] - Antisense knock down of TRPA1, but not TRPM8. alleviates cold hyperalgesia after spinal nerve ligation in rats
Hirokazu Katsura; Koichi Obata; Toshiyuki Mizushima; Hiroki Yamanaka; Kimiko Kobayashi; Yi Dai; Tetsuo Fukuoka; Atsushi Tokunaga; Masafumi Sakagami; Koichi Noguchi
EXPERIMENTAL NEUROLOGY, Jul. 2006, [Reviewed] - The role of ERK signaling and the P2X receptor on mechanical pain evoked by movement of inflamed knee joint
D Seino; A Tokunaga; T Tachibana; S Yoshiya; Y Dai; K Obata; H Yamanaka; K Kobayashi; K Noguchi
PAIN, Jul. 2006, [Reviewed] - BDNF in sensory neurons and chronic pain
K Obata; K Noguchi
NEUROSCIENCE RESEARCH, May 2006, [Reviewed] - Chapter 20 Central sensitization following nerve injury: molecular mechanisms
Koichi Noguchi
Handbook of Clinical Neurology, 2006, [Reviewed] - Cold receptors in the DRG: Basic science and clinical implications
Koichi Obata; Kimiko Kobayashi; Tetsuo Fukuoka; Koichi Noguchi
Reviews in Analgesia, 2006 - Expression patterns and histological aspects of TRP channels in sensory neurons
Tetsuo Fukuoka; Koichi Noguchi
NOCICEPTIVE MEMBRANE, 2006, [Reviewed] - The effect of site and type of nerve injury on the expression of brain-derived neurotrophic factor in the dorsal root ganglion and on neuropathic pain behavior
K Obata; H Yamanaka; K Kobayashi; Y Dai; T Mizushima; H Katsura; T Fukuoka; A Tokunaga; K Noguchi
NEUROSCIENCE, 2006, [Reviewed] - Activation of ERK5 in DRG neurons contributes to acute pain
Toshiyuki Mizushima; Koichi Obata; Takashi Mashimo; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2006 - Activation of ERK5 in DRG neurons contributes to inflammatory pain
Hirokazu Katsura; Koichi Obata; Masafumi Sakagami; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2006 - Activation of ERK5 in the DRG and spinal cord contributes to neuropathic pain
Koichi Obata; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2006 - Noxious cold stimulation induces mitogen-activated protein kinase activation in transient receptor potential (TRP) channels TRPA1- and TRPM8-containing small sensory neurons
T. Mizushima; K. Obata; H. Katsura; H. Yamanaka; K. Kobayashi; Y. Dai; T. Fukuoka; A. Tokunaga; T. Mashimo; K. Noguchi
NEUROSCIENCE, 2006, [Reviewed] - Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with A delta/C-fibers and colocalization with trk receptors
K Kobayashi; T Fukuoka; K Obata; H Yamanaka; Y Dai; A Tokunaga; K Noguchi
JOURNAL OF COMPARATIVE NEUROLOGY, Dec. 2005, [Reviewed] - The tonic inhibition mediated by GABAA receptor in substantia gelatinosa neurons
Ayako Takahashi; Hiroki Yamanaka; Atsushi Tokunaga; Koichi Noguchi; Takashi Mashimo; Ichiro Uchida
International Congress Series, Nov. 2005, [Reviewed] - TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury
K Obata; H Katsura; T Mizushima; H Yamanaka; K Kobayashi; Y Dai; T Fukuoka; A Tokunaga; M Tominaga; K Noguchi
JOURNAL OF CLINICAL INVESTIGATION, Sep. 2005, [Reviewed] - 後根神経節ニューロンでのATP受容体発現及び炎症組織における痛覚過敏
野口 光一; 小林 希実子; 福岡 哲男; 山中 博樹; 戴 毅; 清野 大輔; 徳永 敦
PAIN RESEARCH, Jul. 2005 - 後根損傷後の脊髄後角における組織型プラスミノーゲン活性化因子(tPA)による細胞外タンパク分解
香西 都容子; 山中 博樹; 真下 節; 野口 光一
PAIN RESEARCH, Jul. 2005 - ラット一次感覚ニューロンにおける冷覚受容体TRPA1,TRPM8の局在
小林 希実子; 福岡 哲男; 山中 博樹; 野口 光一
PAIN RESEARCH, Jul. 2005 - 末梢神経損傷後の後根神経節におけるFibroblast growth factor receptor1(FGFR1)の活性化
山中 博樹; 野口 光一
PAIN RESEARCH, Jul. 2005 - Ca2+/calmodulin-dependent protein kinase II in the spinal cord contributes to neuropathic pain in a rat model of mononeuropathy
Y Dai; H Wang; A Ogawa; H Yamanaka; K Obata; A Tokunaga; K Noguchi
EUROPEAN JOURNAL OF NEUROSCIENCE, May 2005, [Reviewed] - Ca2+/calmodulin-protein kinase II alpha in the trigeminal subnucleus caudalis contributes to neuropathic pain following inferior alveolar nerve transection
A Ogawa; Y Dai; H Yamanaka; K Iwata; H Niwa; K Noguchi
EXPERIMENTAL NEUROLOGY, Apr. 2005, [Reviewed] - Expression of mRNA for four subtypes of the proteinase-activated receptor in rat dorsal root ganglia
WJ Zhu; H Yamanaka; K Obata; Y Dai; K Kobayashi; T Kozai; A Tokunaga; K Noguchi
BRAIN RESEARCH, Apr. 2005, [Reviewed] - Differential expression patterns of mRNAs for P2X receptor subunits in neurochemically characterized dorsal root ganglion neurons in the rat
K Kobayashi; T Fukuoka; H Yamanaka; Y Dai; K Obata; A Tokunaga; K Noguchi
JOURNAL OF COMPARATIVE NEUROLOGY, Jan. 2005, [Reviewed] - Activation of p38 MAPK in primary afferent neurons by noxious stimulation and its involvement in the development of thermal hyperalgesia
T Mizushima; K Obata; H Yamanaka; Y Dai; T Fukuoka; A Tokunaga; T Mashimo; K Noguchi
PAIN, Jan. 2005, [Reviewed] - Induction of plasminogen activator inhibitor-1 and -2 in dorsal root ganglion neurons after peripheral nerve injury.
Yamanaka H; Obata K; Fukuoka T; Dai Y; Kobayashi K; Tokunaga A; Noguchi K
Neuroscience, 2005, [Reviewed] - Differential activation of MAPK in injured and uninjured DRG neurons following chronic constriction injury of the sciatic nerve in rats
K Obata; H Yamanaka; Y Dai; T Mizushima; T Fukuoka; A Tokunaga; K Noguchi
EUROPEAN JOURNAL OF NEUROSCIENCE, Dec. 2004, [Reviewed] - Plasma membrane calcium ATPase expression in the rat spinal cord
T Tachibana; H Ogura; A Tokunaga; Y Dai; H Yamanaka; D Seino; K Noguchi
MOLECULAR BRAIN RESEARCH, Nov. 2004, [Reviewed] - Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation
K Obata; H Yamanaka; K Kobayashi; Y Dai; T Mizushima; H Katsura; T Fukuoka; A Tokunaga; K Noguchi
JOURNAL OF NEUROSCIENCE, Nov. 2004, [Reviewed] - Proteinase activated receptorsの後根神経節における発現
朱 万君; 山中 博樹; 野口 光一
解剖学雑誌, Sep. 2004 - 疼痛メカニズム探求の新展開 ニューロパチックペインの新規メカニズムとしてのセリンプロテアーゼ及び細胞接着因子の変化(The frontier of research on pain mechanisms: Changes in serine protease and cell adhesion molecule in nociceptive pathway as novel pathomechanisms of neuropathic pain)
野口 光一; 山中 博樹
神経化学, Aug. 2004 - 脊髄後角第2層における持続性GABA,A受容体持続的抑制性電流(The tonic inhibition mediated by γ Aminobutyric AcidA receptor in substantia gelatinosa neurons)
高橋 亜矢子; 内田 一郎; 真下 節; 山中 博樹; 徳永 敦; 野口 光一
神経化学, Aug. 2004 - 末梢神経損傷による接着因子L1-CAMの発現変化と疼痛発現への関与(Expression of L1-CAM in rat dorsal root ganglia and spinal cord following nerve injury)
山中 博樹; 野口 光一
神経化学, Aug. 2004 - Contribution of degeneration of motor and sensory fibers to pain behavior and the changes in neurotrophic factors in rat dorsal root ganglion
K Obata; H Yamanaka; Y Dai; T Mizushima; T Fukuoka; A Tokunaga; H Yoshikawa; K Noguchi
EXPERIMENTAL NEUROLOGY, Jul. 2004, [Reviewed] - Activation of extracellular signal-regulated protein kinase in dorsal horn neurons in the rat neuropathic intermittent claudication model
Y Liu; K Obata; H Yamanaka; Y Dai; T Fukuoka; A Tokunaga; K Noguchi
PAIN, May 2004, [Reviewed] - Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain
Y Dai; T Moriyama; T Higashi; K Togashi; K Kobayashi; H Yamanaka; M Tominaga; K Noguchi
JOURNAL OF NEUROSCIENCE, May 2004, [Reviewed] - Contribution of sensitized P2X receptors in inflamed tissue to the mechanical hypersensitivity revealed by phosphorylated ERK in DRG neurons
Y Dai; T Fukuoka; H Wang; H Yamanaka; K Obata; A Tokunaga; K Noguchi
PAIN, Apr. 2004, [Reviewed] - MAPK activation in nociceptive neurons and pain hypersensitivity
K Obata; K Noguchi
LIFE SCIENCES, Apr. 2004, [Reviewed] - Enhancement of stimulation-induced ERK activation in the spinal dorsal horn and gracile nucleus neurons in rats with peripheral nerve injury
H Wang; Y Dai; T Fukuoka; H Yamanaka; K Obata; A Tokunaga; K Noguchi
EUROPEAN JOURNAL OF NEUROSCIENCE, Feb. 2004, [Reviewed] - Tissue plasminogen activator in primary afferents induces dorsal horn excitability and pain response after peripheral nerve injury
H Yamanaka; K Obata; T Fukuoka; Y Dai; K Kobayashi; A Tokunaga; K Noguchi
EUROPEAN JOURNAL OF NEUROSCIENCE, Jan. 2004, [Reviewed] - Changes in DRG neurons and spinal excitability in neuropathy
Koichi Noguchi; Koichi Obata; Yi Dai; Mantyh; Devor; Dray; Belmonte; Perl
Novartis Foundation Symposium, 2004, [Reviewed] - Activation of extracellular signal-regulated protein kinase in the dorsal root ganglion following inflammation near the nerve cell body
K Obata; H Yamanaka; Y Dai; T Mizushima; T Fukuoka; A Tokunaga; K Noguchi
NEUROSCIENCE, 2004, [Reviewed] - Protease-activated receptor 2によるTRPV1活性の増強
戴 毅; 森山 朋子; 冨樫 和也; 東 智広; 山中 博樹; 富永 真琴; 野口 光一
PAIN RESEARCH, Dec. 2003 - 膝関節炎モデルにおける後根神経節細胞のExtracellular Signal-Regulated Kinaseのリン酸化
清野 大輔; 徳永 敦; 橘 俊哉; 野口 光一; 圓尾 宗司
日本整形外科学会雑誌, Aug. 2003 - Increase of preprotachykinin mRNA in the uninjured mandibular neurons after rat infraorbital nerve transection
K Tsuzuki; T Fukuoka; M Sakagami; K Noguchi
NEUROSCIENCE LETTERS, Jul. 2003, [Reviewed] - Possible involvement of P2Y(2) metabotropic receptors in ATP-Induced transient receptor potential vanilloid receptor 1-mediated thermal hypersensitivity
T Moriyama; T Iida; K Kobayashi; T Higashi; T Fukuoka; H Tsumura; C Leon; N Suzuki; K Inoue; C Gachet; K Noguchi; M Tominaga
JOURNAL OF NEUROSCIENCE, Jul. 2003, [Reviewed] - The effects of dexmedetomidine and halothane on Fos expression in the spinal dorsal horn using a rat postoperative pain model
N Shimode; T Fukuoka; M Tanimoto; C Tashiro; A Tokunaga; K Noguchi
NEUROSCIENCE LETTERS, May 2003, [Reviewed] - Differential activation of extracellular signal-regulated protein kinase in primary afferent neurons regulates brain-derived neurotrophic factor expression after peripheral inflammation and nerve injury
K Obata; H Yamanaka; Y Dai; T Tachibana; T Fukuoka; A Tokunaga; H Yoshikawa; K Noguchi
JOURNAL OF NEUROSCIENCE, May 2003, [Reviewed] - Increased expression of 3 beta-hydroxysteroid dehydrogenase mRNA in dorsal root ganglion neurons of adult rats following peripheral nerve injury
N Hashimoto; H Yamanaka; T Mizushima; K Noguchi
NEUROSCIENCE LETTERS, Apr. 2003, [Reviewed] - 末梢神経損傷に伴うplasminogen activatorの発現とその疼痛発現への影響
山中 博樹; 野口 光一
解剖学雑誌, Apr. 2003 - Induction of neuronal nitric oxide synthase by sympathetic denervation is mediated via alpha 2-adrenoceptors in the jejunal myenteric plexus
K Nishizaki; K Nakao; H Ishii; H Yamanaka; A Tokunaga; K Nakagawa; T Yamamura; K Noguchi
BRAIN RESEARCH, Mar. 2003, [Reviewed] - Changes in phosphorylation of ERK and Fos expression in dorsal horn neurons following noxious stimulation in a rat model of neuritis of the nerve root
Y Kominato; T Tachibana; Y Dai; H Tsujino; S Maruo; K Noguchi
BRAIN RESEARCH, Mar. 2003, [Reviewed] - Contribution of injured and uninjured dorsal root ganglion neurons to pain behavior and the changes in gene expression following chronic constriction injury of the sciatic nerve in rats
K Obata; H Yamanaka; T Fukuoka; D Yi; A Tokunaga; N Hashimoto; H Yoshikawa; K Noguchi
PAIN, Jan. 2003, [Reviewed] - Hard-food mastication suppresses complete Freund's adjuvant-induced nociception
A Ogawa; T Morimoto; JW Hu; Y Tsuboi; A Tashiro; K Noguchi; H Nakagawa; K Iwata
NEUROSCIENCE, 2003, [Reviewed] - Expression of auxiliary beta subunits of sodium channels in primary afferent neurons and the effect of nerve injury.
Takahashi N; Kikuchi S; Dai Y; Kobayashi K; Fukuoka T; Noguchi K
Neuroscience, 2003, [Reviewed] - Phosphorylation of extracellular signal-regulated kinase in primary afferent neurons by noxious stimuli and its involvement in peripheral sensitization
Y Dai; K Iwata; T Fukuoka; E Kondo; A Tokunaga; H Yamanaka; T Tachibana; Y Liu; K Noguchi
JOURNAL OF NEUROSCIENCE, Sep. 2002, [Reviewed] - VR1, but not P2X(3), increases in the spared L4 DRG in rats with L5 spinal nerve ligation
T Fukuoka; A Tokunaga; T Tachibana; Y Dai; H Yamanaka; K Noguchi
PAIN, Sep. 2002, [Reviewed] - Expression of neurotrophic factors in the dorsal root ganglion in a rat model of lumbar disc herniation
K Obata; H Tsujino; H Yamanaka; D Yi; T Fukuoka; N Hashimoto; K Yonenobu; H Yoshikawa; K Noguchi
PAIN, Sep. 2002, [Reviewed] - VR1, but not P2X(3), increases in the spared L4 DRG in rats with L5 spinal nerve ligation
T Fukuoka; A Tokunaga; T Tachibana; Y Dai; H Yamanaka; K Noguchi
PAIN, Sep. 2002, [Reviewed] - Expression of neurotrophic factors in the dorsal root ganglion in a rat model of lumbar disc herniation
K Obata; H Tsujino; H Yamanaka; D Yi; T Fukuoka; N Hashimoto; K Yonenobu; H Yoshikawa; K Noguchi
PAIN, Sep. 2002, [Reviewed] - Contribution of the spared primary afferent neurons to the pathomechanisms of neuropathic pain
T Fukuoka; K Noguchi
MOLECULAR NEUROBIOLOGY, Aug. 2002, [Reviewed] - Analysis of gene expression following spinal cord injury in rat using complementary DNA microarray
T Tachibana; K Noguchi; MA Ruda
NEUROSCIENCE LETTERS, Jul. 2002, [Reviewed] - Analysis of gene expression following spinal cord injury in rat using complementary DNA microarray
T Tachibana; K Noguchi; MA Ruda
NEUROSCIENCE LETTERS, Jul. 2002, [Reviewed] - Heme oxygenase-1 expression after spinal cord injury: The induction in activated neutrophils
Y Liu; T Tachibana; Y Dai; E Kondo; T Fukuoka; H Yamanaka; K Noguchi
JOURNAL OF NEUROTRAUMA, Apr. 2002, [Reviewed] - Expression of activating transcription factor 3 and growth-associated protein 43 in the rat geniculate ganglion neurons after chorda tympani injury
K Tsuzuki; K Noguchi; D Mohri; H Yasuno; M Umemoto; C Shimobayashi; K Fukazawa; M Sakagami
ACTA OTO-LARYNGOLOGICA, Mar. 2002, [Reviewed] - Plastic changes in nociceptive transmission of the rat spinal cord with advancing age
K Iwata; T Fukuoka; E Kondo; Y Tsuboi; A Tashiro; K Noguchi; Y Masuda; T Morimoto; K Kanda
JOURNAL OF NEUROPHYSIOLOGY, Feb. 2002, [Reviewed] - Involvement of glutamate receptors on hyperexcitability of wide dynamic range neurons in the gracile nucleus of the rats with experimental mononeuropathy
E Kondo; K Iwata; A Ogawa; A Tashiro; Y Tsuboi; T Fukuoka; H Yamanaka; Y Dai; T Morimoto; K Noguchi
PAIN, Jan. 2002, [Reviewed] - Expression of Apc2 during mouse development
Hiroki Yamanaka; Norio Hashimoto; Kumiko Koyama; Hidewaki Nakagawa; Yusuke Nakamura; Koichi Noguchi
Brain research. Gene expression patterns, 2002, [Reviewed] - Involvement of glutamate receptors on hyperexcitability of wide dynamic range neurons in the gracile nucleus of the rats with experimental mononeuropathy
E Kondo; K Iwata; A Ogawa; A Tashiro; Y Tsuboi; T Fukuoka; H Yamanaka; Y Dai; T Morimoto; K Noguchi
PAIN, Jan. 2002, [Reviewed] - 末梢神経損傷後のPlasminogen activatorの後根神経節と脊髄後角における発現
山中 博樹; 野口 光一
PAIN RESEARCH, Dec. 2001 - Expression of hepatocyte growth factor in primary sensory neurons of adult rats
N Hashimoto; H Yamanaka; T Fukuoka; K Obata; T Mashimo; K Noguchi
MOLECULAR BRAIN RESEARCH, Dec. 2001, [Reviewed] - 末梢神経損傷時の後根神経節・脊髄後角におけるPlasminogen activatorとinhibitorの発現
山中 博樹; 橋本 典夫; 野口 光一
神経化学, Sep. 2001 - NF-kappa B decoy suppresses cytokine expression and thermal hyperalgesia in a rat neuropathic pain model.
G Sakaue; M Shimaoka; T Fukuoka; T Hiroi; T Inoue; N Hashimoto; T Sakaguchi; Y Sawa; R Morishita; H Kiyono; K Noguchi; T Mashimo
Neuroreport, Jul. 2001, [Reviewed] - Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model
T Fukuoka; E Kondo; Y Dai; N Hashimoto; K Noguchi
JOURNAL OF NEUROSCIENCE, Jul. 2001, [Reviewed] - The effect of electroacupuncture on pain behaviors and noxious stimulus-evoked fos expression in a rat model of neuropathic pain
Y Dai; E Kondo; T Fukuoka; A Tokunaga; K Miki; K Noguchi
JOURNAL OF PAIN, Jun. 2001, [Reviewed] - Expression of HGF and cMet in the peripheral nervous system of adult rats following sciatic nerve injury
N Hashimoto; H Yamanaka; T Fukuoka; Y Dai; K Obata; T Mashimo; K Noguchi
NEUROREPORT, May 2001, [Reviewed] - Differential regulation of P2X(3) mRNA expression by peripheral nerve injury in intact and injured neurons in the rat sensory ganglia
K Tsuzuki; E Kondo; T Fukuoka; D Yi; H Tsujino; M Sakagami; K Noguchi
PAIN, Apr. 2001, [Reviewed] - Change in gene expression in facial nerve nuclei and the effect of superoxide dismutase in a rat model of ischemic facial paralysis
D Mohri; F Satomi; E Kondo; T Fukuoka; M Sakagami; K Noguchi
BRAIN RESEARCH, Mar. 2001, [Reviewed] - A selective increase in Fos expression in the spinal dorsal horn neurons following quantitative thermal stimulation in rats with experimental mononeuropathy (joint worked)
Dai Y; Iwata K; Kondo E; Morimoto T; Noguchi K
Pain, Feb. 2001, [Reviewed] - A selective increase in Fos expression in spinal dorsal horn neurons following graded thermal stimulation in rats with experimental mononeuropathy
Y Dai; K Iwata; E Kondo; T Morimoto; K Noguchi
PAIN, Feb. 2001, [Reviewed] - Nerve growth factor applied onto the olfactory epithelium alleviates degenerative changes of the olfactory receptor neurons following axotomy
H Yasuno; K Fukazawa; T Fukuoka; E Kondo; M Sakagami; K Noguchi
BRAIN RESEARCH, Dec. 2000, [Reviewed] - Suppression of neuropeptides' mRNA expression by herbal medicines in a rat model of peripheral inflammation
Y Dai; K Miki; T Fukuoka; A Tokunaga; T Tachibana; E Kondo; K Noguchi
LIFE SCIENCES, Nov. 2000, [Reviewed] - Dorsal column-thalamic pathway is involved in thalamic hyperexcitability following peripheral nerve injury: a lesion study in rats with experimental mononeuropathy
K Miki; K Iwata; Y Tsuboi; T Morimoto; E Kondo; Y Dai; K Ren; K Noguchi
PAIN, Mar. 2000, [Reviewed] - マウス個体発生におけるAPCL mRNAの発現
山中 博樹; 金銅 英二; 野口 光一; 中川 英刀; 小山 久美子; 中村 祐輔
解剖学雑誌, Feb. 2000 - Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury
H Tsujino; E Kondo; T Fukuoka; Y Dai; A Tokunaga; K Miki; K Yonenobu; T Ochi; K Noguchi
MOLECULAR AND CELLULAR NEUROSCIENCE, Feb. 2000, [Reviewed] - Differential effect of brain-derived neurotrophic factor on high-threshold mechanosensitivity in a rat neuropathic pain model
K Miki; T Fukuoka; A Tokunaga; E Kondo; Y Dai; K Noguchi
NEUROSCIENCE LETTERS, Jan. 2000, [Reviewed] - The role of neighboring intact dorsal root ganglion neurons in a rat neuropathic pain model
T Fukuoka; A Tokunaga; E Kondo; K Noguchi
PROCEEDINGS OF THE 9TH WORLD CONGRESS ON PAIN, 2000, [Reviewed] - Excitability of spinal cord and gracile nucleus neurons in rats with chronically injured sciatic nerve examined by c-fos expression
A Tokunaga; E Kondo; T Fukuoka; K Miki; Y Dai; H Tsujino; K Noguchi
BRAIN RESEARCH, Nov. 1999, [Reviewed] - Differential regulation of alpha- and beta-CGRP mRNAs within oculomotor, trochlear, abducens, and trigeminal motoneurons in response to axotomy
T Fukuoka; A Tokunaga; E Kondo; K Miki; T Tachibana; K Noguchi
MOLECULAR BRAIN RESEARCH, Jan. 1999, [Reviewed] - Effects of halothane, ketamine and nitrous oxide on dynorphin mRNA expression in dorsal horn neurons after peripheral tissue injury
M Tanimoto; T Fukuoka; K Miki; A Tokunaga; C Tashiro; K Noguchi
BRAIN RESEARCH, Nov. 1998, [Reviewed] - Change in mRNAs for neuropeptides and the GABA(A) receptor in dorsal root ganglion neurons in a rat experimental neuropathic pain model
T Fukuoka; A Tokunaga; E Kondo; K Miki; T Tachibana; K Noguchi
PAIN, Oct. 1998, [Reviewed] - Dynorphin mRNA expression in dorsal horn neurons after traumatic spinal cord injury: Temporal and spatial analysis using in situ hybridization
T Tachibana; K Miki; T Fukuoka; A Arakawa; M Taniguchi; S Maruo; K Noguchi
JOURNAL OF NEUROTRAUMA, Jul. 1998, [Reviewed] - Responses of dorsal column nuclei neurons in rats with experimental mononeuropathy
K Miki; K Iwata; Y Tsuboi; R Sumino; T Fukuoka; T Tachibana; A Tokunaga; K Noguchi
PAIN, Jun. 1998, [Reviewed] - Calcitonin gene-related peptide increase in the rat spinal dorsal horn and dorsal column nucleus following peripheral nerve injury: Up-regulation in a subpopulation of primary afferent sensory neurons
K Miki; T Fukuoka; A Tokunaga; K Noguchi
NEUROSCIENCE, Feb. 1998, [Reviewed] - Expression of beta-calcitonin gene-related peptide in axotomized rubrospinal neurons and the effect of brain derived neurotrophic factor
T Fukuoka; K Miki; Yoshiya, I; K Noguchi
BRAIN RESEARCH, Sep. 1997, [Reviewed] - Localization of myogenin, c-fos, c-jun, and muscle-specific gene mRNAs in regenerating rat skeletal muscle
Katsuya Kami; Koichi Noguchi; Emiko Senba
Cell and Tissue Research, Apr. 1995 - GENE-REGULATION IN AN ASCENDING NOCICEPTIVE PATHWAY - INFLAMMATION-INDUCED INCREASE IN PREPROTACHYKININ MESSENGER-RNA IN RAT LAMINA-I SPINAL PROJECTION NEURONS
K NOGUCHI; MA RUDA
JOURNAL OF NEUROSCIENCE, Jul. 1992, [Reviewed] - NEONATAL CAPSAICIN TREATMENT ATTENUATES SPINAL FOS ACTIVATION AND DYNORPHIN GENE-EXPRESSION FOLLOWING PERIPHERAL TISSUE INFLAMMATION AND HYPERALGESIA
JLK HYLDEN; K NOGUCHI; MA RUDA
JOURNAL OF NEUROSCIENCE, May 1992, [Reviewed] - Changes in expression of peptides in rat facial motoneurons after facial nerve crushing and resection
Takanori Saika; Emiko Senba; Koichi Noguchi; Makoto Sato; Takeshi Kubo; Toru Matsunaga; Masaya Tohyama
Molecular Brain Research, 1991, [Reviewed] - Effects of nerve crush and transection on mRNA levels for nerve growth factor receptor in the rat facial motoneurons
Takanori Saika; Emiko Senba; Koichi Noguchi; Makoto Sato; Shigetaka Yoshida; Takeshi Kubo; Toru Matsunaga; Masaya Tohyama
Molecular Brain Research, 1991, [Reviewed] - THE DIFFERENTIAL EXPRESSION PATTERN OF THE MESSENGER-RNAS ENCODING BETA SUBUNITS (BETA-1, BETA-2, AND BETA-3) OF GABA-A RECEPTOR IN RAT-BRAIN
JH ZHANG; M SATO; K NOGUCHI; M TOHYAMA
NEURORECEPTOR MECHANISMS IN BRAIN, 1991, [Reviewed] - THE DIFFERENTIAL EXPRESSION PATTERNS OF THE MESSENGER-RNAS ENCODING BETA-SUBUNITS (BETA-1, BETA-2 AND BETA-3) OF GABA-A RECEPTOR IN THE OLFACTORY-BULB AND ITS RELATED AREAS IN THE RAT-BRAIN
JH ZHANG; M SATO; K NOGUCHI; M TOHYAMA
NEUROSCIENCE LETTERS, Nov. 1990, [Reviewed] - DIFFERENT ONTOGENIC PROFILES OF CELLS EXPRESSING PREPRONEUROTENSIN NEUROMEDIN-N MESSENGER-RNA IN THE RAT POSTERIOR CINGULATE CORTEX AND THE HIPPOCAMPAL-FORMATION
M SATO; Y LEE; JH ZHANG; S SHIOSAKA; K NOGUCHI; Y MORITA; M TOHYAMA
DEVELOPMENTAL BRAIN RESEARCH, Jul. 1990, [Reviewed] - Postnatal development of preproenkephalin mRNA containing neurons in the rat lower brainstem
Yasuhiro Morita; Jian‐Hua Zhang; Takashi Hironaka; Emiko Tateno; Koichi Noguchi; Makoto Sato; Hiroshi Kiyama; Masaya Tohyama
Journal of Comparative Neurology, 1990, [Reviewed] - α-CGRP and β-CGRP mRNAs are differentially regulated in the rat spinal cord and dorsal root ganglion
Koichi Noguchi; Emiko Senba; Yasuhiro Morita; Makoto Sato; Masaya Tohyama
Molecular Brain Research, 1990, [Reviewed] - Co-expression of α-CGRP and β-CGRP mRNAs in the rat dorsal root ganglion cells
Koichi Noguchi; Emiko Senba; Yasuhiro Morita; Makoto Sato; Masaya Tohyama
Neuroscience Letters, Jan. 1990, [Reviewed] - Postnatal ontogeny of POMC gene expression in the rat pituitary: an analysis by in situ hybridization histochemistry
Ya-Qi Wang; Makoto Sato; Yasuhiro Morita; Koichi Noguchi; Hiroshi Kiyama; Masaya Tohyama
Developmental Brain Research, May 1989, [Reviewed] - PREPROENKEPHALIN GENE-EXPRESSION IN THE RAT SPINAL-CORD AFTER NOXIOUS STIMULI
K NOGUCHI; Y MORITA; H KIYAMA; M SATO; K ONO; M TOHYAMA
MOLECULAR BRAIN RESEARCH, May 1989, [Reviewed] - Prepro-VIP and preprotachykinin mRNAs in the rat dorsal root ganglion cells following peripheral axotomy
Koichi Noguchi; Emiko Senba; Yasuhiro Morita; Makoto Sato; Masaya Tohyama
Molecular Brain Research, 1989, [Reviewed] - A noxious stimulus induces the preprotachykinin-A gene expression in the rat dorsal root ganglion: a quantitative study using in situ hybridization histochemistry
Koichi Noguchi; Yasuhiro Morita; Hiroshi Kiyama; Keiro Ono; Masaya Tohyama
Molecular Brain Research, 1988, [Reviewed]
MISC
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段韶基; 段韶基; 近藤隆; 神田浩里; 河野友彰; 福島政司; 富田寿彦; 大島忠之; 福井広一; 戴毅; 戴毅; 野口光一; 三輪洋人
日本潰瘍学会プログラム・抄録集, 2021 - ラット母子分離ストレスモデルにおける胃十二指腸の微小炎症は胃の痛覚過敏に関与する(Micro-inflammation in the Gastroduodenal Tract Contributes to Gastric Pain Hypersensitivity in MS Model Rats)
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PAIN RESEARCH, Dec. 2020 - 【運動器の痛み:どこから来るのか?どこへ行くのか?】(Part1)運動器の痛み どこから来るのか? 疼痛の発生メカニズム
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Bone Joint Nerve, Oct. 2020 - EARLY-LIFE ADVERSITY INDUCESD SEX-DEPENDENT GASTRIC HYPRSENSITIVITY
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日本自律神経学会総会プログラム・抄録集, Oct. 2018 - 末梢神経 脊髄ネットワークにおける痛覚伝達メカニズム 神経傷害性疼痛モデル動物の脊髄後角における損傷C線維の形態的可塑性
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PAIN RESEARCH, Jun. 2017 - 一次知覚神経におけるAMPキナーゼによるTRPA1膜発現の制御
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PAIN RESEARCH, Jun. 2017 - 神経障害性疼痛の分子メカニズム
野口 光一
自律神経, Dec. 2016 - 神経障害性疼痛モデルラットの脊髄後角におけるIL-4およびIL-4受容体の発現変化
奥谷 博愛; 小林 希実子; 山中 博樹; 大久保 正道; 廣瀬 宗孝; 野口 光一
PAIN RESEARCH, Jun. 2016 - 神経障害性疼痛のメカニズム
野口 光一
日本自律神経学会総会プログラム・抄録集, Oct. 2015 - 痛みの分子メカニズムとIASP
野口 光一
日本ペインクリニック学会誌, Jun. 2015 - 痛みの分子メカニズム
野口 光一
Journal of Neurosciences for Pain Research, Apr. 2015 - 脊椎関連難治性疼痛に対する診療アプローチの現状と課題 脊髄障害性疼痛に対するカルシウムチャネルα2δ-1サブユニット作動薬の効果と作用機序
橘 俊哉; 楠山 一樹; 圓尾 圭史; 井上 真一; 有住 文博; 山中 博樹; 野口 光一; 吉矢 晋一
Journal of Spine Research, Mar. 2015 - 神経障害性疼痛のメカニズム 神経可塑性に注目して
野口 光一
Practice of Pain Management, Dec. 2014 - 脊髄損傷モデルにおけるカルシウムチャネルα2δ-1サブユニットの発現
楠山 一樹; 橘 俊哉; 山中 博樹; 野口 光一; 吉矢 晋一
Journal of Musculoskeletal Pain Research, Sep. 2014 - 【痛みのマネジメントupdate 基礎知識から緩和ケアまで】痛みの基礎知識 痛みの発生のメカニズム 痛みの受容器
戴 毅; 野口 光一
日本医師会雑誌, Jun. 2014 - ロイコトリエンは末梢神経損傷後に脊髄後角ニューロンのNMDA受容体の反応性を増加させる
清行 康邦; 山中 博樹; 小林 希実子; 谷口 亘; 大久保 正道; 中塚 映政; 野口 光一
Journal of Musculoskeletal Pain Research, Nov. 2013 - 末梢神経損傷後の脊髄および後根神経節におけるColony-stimulating factorとそれら受容体mRNAの発現
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Journal of Musculoskeletal Pain Research, Nov. 2013 - EtodolacはTRPA1を活性化し脱感作する(Etodolac activates and desensitizes TRPA1)
王 勝蘭; 戴 毅; 野口 光一
Journal of Musculoskeletal Pain Research, Nov. 2013 - ロイコトリエンは末梢神経損傷後に脊髄後角ニューロンのNMDA受容体の反応性を増加させる
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PAIN RESEARCH, Jul. 2013 - 【最新生理活性脂質研究-実験手法、基礎的知識とその応用-】(第4章)臨床編 痛みとプロスタグランジン・ロイコトリエン
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遺伝子医学MOOK, May 2013 - 【整形外科関連疾患での慢性の痛み】基礎/臨床研究 疼痛を惹起する運動器疾患モデルでの基礎的研究 運動器疾患の疼痛の慢性化
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ペインクリニック, Apr. 2013 - 脊髄マイクログリアにおけるPGD2とTXA2合成酵素および受容体発現と神経障害疼痛行動への関与
山中博樹; 神田浩里; 小林希実子; 野口光一
日本解剖学会総会・全国学術集会講演プログラム・抄録集, 2013 - 末梢神経障害後の脊髄におけるPGI2合成酵素および受容体の発現と疼痛行動への関与
神田 浩里; 小林 希実子; 山中 博樹; 野口 光一
Journal of Musculoskeletal Pain Research, Oct. 2012 - 下歯槽神経損傷モデルにおける三叉神経脊髄路核でのIL-18の発現増加
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日本歯科麻酔学会雑誌, Sep. 2012 - 下歯槽神経損傷後の三叉神経脊髄路核におけるIL-18の発現増加
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日本慢性疼痛学会プログラム・抄録集, Feb. 2012 - 痛みの分子メカニズム
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日本マイクロサージャリー学会会誌, Jul. 2011 - ラット胃伸展刺激によるp38 MAPKの活性化とTRPA1の関与
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日本消化器病学会雑誌, Mar. 2011 - 下歯槽神経損傷におけるIL-18の発現増加とアロディニア
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日本歯科麻酔学会雑誌, Sep. 2010 - 痛みの分子メカニズム
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PAIN RESEARCH, Jul. 2009 - 脊髄マイクログリアにおけるinterleukin-1β converting enzyme(ICE)の発現増加とアロディニア
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PAIN RESEARCH, Jul. 2009 - 【神経障害性疼痛】痛みの機序 MAPKの活性化と疼痛
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Clinical Neuroscience, May 2009 - 医学部4年生必修科目としての東洋医学教育導入の成果 アンケート調査からの検討
戴 毅; 夏秋 優; 野口 光一
日本東洋医学雑誌, May 2009 - 【神経障害性疼痛の基礎と臨床】神経障害性疼痛に関する基礎研究 神経障害性疼痛における一次知覚ニューロンの役割
小畑 浩一; 三好 歓; 野口 光一
ペインクリニック, Apr. 2009 - 「痛み」 その発生機序と臨床的制御の意義 炎症性疼痛の分子メカニズム
野口 光一
日本リウマチ学会総会・学術集会・国際リウマチシンポジウムプログラム・抄録集, Mar. 2009 - 慢性痛のメカニズム 若手研究者による新知見 神経因性疼痛発現における脊髄IL-18シグナル伝達経路の関与
小畑 浩一; 三好 歓; 野口 光一
日本慢性疼痛学会プログラム・抄録集, Feb. 2009 - 侵害受容システムにおけるシグナル伝達と疼痛関連分子の制御機構
野口 光一
上原記念生命科学財団研究報告集, Dec. 2008 - ラット胃伸展刺激に伴う内臓痛におけるTRPA1の関与
近藤 隆; 小畑 浩一; 櫻井 淳; 野口 光一; 三輪 洋人
日本消化器病学会雑誌, Sep. 2008 - 一次知覚ニューロンにおける電位依存性ナトリウムチャネルサブタイプの発現比較
福岡 哲男; 小林 希実子; 山中 博樹; 戴 毅; 小畑 浩一; 野口 光一
PAIN RESEARCH, Jul. 2008 - 【痛みのメカニズムとその制御】TRPファミリー受容体と痛み(基礎)
戴 毅; 野口 光一
BIO Clinica, May 2008 - ラット後根神経節におけるロイコトリエン受容体の発現
大久保 正道; 山中 博樹; 野口 光一
全日本鍼灸学会雑誌, May 2008 - ラット胃の伸展刺激によるp38 MAPKの活性化
近藤 隆; 小畑 浩一; 櫻井 淳; 三輪 洋人; 野口 光一
解剖学雑誌, Mar. 2008 - ラット後根神経節におけるロイコトリエン受容体の発現
大久保 正道; 山中 博樹; 小林 希実子; 野口 光一
解剖学雑誌, Mar. 2008 - 脊髄マイクログリアにおけるTLR3の活性化とアロディニア
小畑 浩一; 三好 歓; 野口 光一
解剖学雑誌, Mar. 2008 - IL-18を介した脊髄マイクログリア・アストロサイト相互作用と神経因性疼痛
三好 歓; 小畑 浩一; 野口 光一
解剖学雑誌, Mar. 2008 - ラット胃の伸展刺激による脊髄神経系の解剖
櫻井 淳; 小畑 浩一; 野口 光一; 三輪 洋人
日本消化器病学会雑誌, Sep. 2007 - C-15 炎症関連因子によるTRPA1受容体の活性調節機構(消化器・チャンネル,一般演題口演,第24回和漢医薬学会大会 和漢薬の複雑さ-経験知と科学知-)
戴毅; 王勝蘭; 野口光一
和漢医薬学雑誌, 20 Aug. 2007 - SNLモデルの脊髄ミクログリアにおけるSrc-family kinasesの活性化と痛覚過敏
桂 弘和; 小畑 浩一; 阪上 雅史; 野口 光一
解剖学雑誌, Mar. 2006 - 一次知覚ニューロンにおけるp75NTRの発現変化と痛み
小畑 浩一; 野口 光一
解剖学雑誌, Mar. 2006 - Role of MAP kinases in sensory neurons on pain transmission
NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 15 Dec. 2005 - 侵害受容ニューロンにおけるMAPKの活性化と痛み (第5土曜特集 痛みシグナルの制御機構と最新治療エビデンス) -- (疼痛の生理機構と分子メカニズム)
小畑 浩一; 野口 光一
医学のあゆみ, 30 Oct. 2004 - Phosphorylation of Extracellular Signal-Regulated Kinase in Primary Afferent Neurons by Noxious Stimuli and its Involvement in Peripheral Sensitization
Dj Yi; NOGOCHI Koichi
Acta medica Hyogoensia, 25 Aug. 2004 - 痛み伝達にかかわる細胞内シグナル伝達系 (特集 痛みの分子メカニズムと臨床--基礎研究と治療の最前線) -- (REVIEW 1:痛みの分子メカニズム)
戴 毅; 小畑 浩一; 野口 光一
モレキュラ-メディシン, Jun. 2004 - Phenotypic change in the spared DRG neurons after peripheral nerve lesion
FUKUOKA Tetsuo; NOGUCHI Koichi
The Journal of the Japan Society of Pain Clinicians, 25 Apr. 2003 - Expression of brain-derived neurotrophic factor in rat dorsal root ganglion in spinal nerve root transection model
OBATA K.
日本脊椎脊髄病学会雑誌 = The journal of the Japan Spine Research Society, 20 Feb. 2003 - Plasma membrane Ca^2+ATPase mRNA expression in neuropathic pain model
OGURA H.
日本脊椎脊髄病学会雑誌 = The journal of the Japan Spine Research Society, 20 Feb. 2003 - 脊髄神経根切断モデルの脊髄後根神経節(DRG)における neeve growth factor brain-derived neurotrophic factor(BDNF)の発現
小畑浩一; 野口光一; 石井崇大; 坂浦博伸; 田村裕一; 向井克容; 細野昇; 吉川秀樹
日本脊椎脊髄病学会雑誌 = The journal of the Japan Spine Research Society, 20 Feb. 2003 - Neuronal plasticity in the spinal cord and sensory ganglia in animal modes of chronic pain
OBATA Koichi; NOGUCHI Koichi
日本整形外科學會雜誌, 25 Jan. 2003 - Expression of nerve growth factor in rat dorsal root ganglion in spinal nerve root transection model
OBATA K.
日本脊椎脊髄病学会雑誌 = The journal of the Japan Spine Research Society, 26 Apr. 2002 - Expression of MAP kinase and c-fos to the nociceptive stimulus in a rat lumbar disc herniation model at the early stage
KOMINATO Y.
日本脊椎脊髄病学会雑誌 = The journal of the Japan Spine Research Society, 26 Apr. 2002 - Plasma membrane Ca^<2+> ATPase mRNA expression following spinal cord injury
TACHIBANA T.
日本脊椎脊髄病学会雑誌 = The journal of the Japan Spine Research Society, 26 Apr. 2002 - 第23回 日本疼痛学会印象記 : 基礎部門
野口光一
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 31 Mar. 2002 - 腰椎椎間板ヘルニアモデルの脊髄後根神経節(DRG)におけるbrain-derivedneurotrophic factor(BDNF)の発現
小畑浩一; 辻野宏明; 三木健司; 野口光一; 向井克容; 佐藤巌; 金澤淳則; 米延策雄; 吉川秀樹
日本脊椎脊髄病学会雑誌 = The journal of the Japan Spine Research Society, 27 Apr. 2001 - Changes in N-methyl-D-aspartate receptor gene expression and a neuronal phenotypic switch in bralnstem pain modulatory circuitry after inflammation
MIKI K.; QIQI Zhou; TERAYAMA Ruji; RONALD Dubner; RE Ren
日本脊椎脊髄病学会雑誌 = The journal of the Japan Spine Research Society, 27 Apr. 2001 - Pain mechanisms in primary afferent neurons
NOGUCHI K.
日本脊椎脊髄病学会雑誌 = The journal of the Japan Spine Research Society, 27 Apr. 2001 - Asian Pain Symposiumを開催して
野口光一
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 31 Mar. 2001 - Expression of Neurotrophic Factor in Rat Dorsal Root Ganglion Following Spinal Nerve Root Irritation with Autologous Nucleus Pulposus
OBATA Koichi; TSUJINO Hiroaki; NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 02 Dec. 2000 - The spared L4 DRG neurons increase BDNF expression in Chung model rats
FUKUOKA Testuo; KONDO Eiji; DAI Yi; NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 02 Dec. 2000 - 痛覚伝達路の可塑性と遺伝子 (12月第1土曜特集 痛みとその制御機構--分子メカニズムと治療の最前線) -- (疼痛の生理機構と分子メカニズム)
福岡 哲男; 野口 光一
医学のあゆみ, 02 Dec. 2000 - Change in gene expression in the ipsilateral L4 DRG neurons in Chung model rats and neurotrophic factors
FUKUOKA Tetsuo; TOKUNAGA Atsushi; KONDO Eiji; NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 11 Dec. 1999 - Fos expression in the spinal dorsal horn neurons following quantitative thermal stimulation in rats with CCI
DAI Yi; IWATA Kohichi; KONDO Eiji; NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 11 Dec. 1999 - Effect of infraorbital nerve transection on P2X3 mRNA expression in trigeminal ganglion neurons
TSUZUKI Kenzo; TSUJINNO Hiroaki; NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 11 Dec. 1999 - EXPRESSION OF ATF3 IN PERIPHERAL NERVOUS SYSTEM FOLLOWING AXOTOMY
TSUJINO Hiroaki; TSUZUKI Kenzo; NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 11 Dec. 1999 - Expression of neuropeptides in geniculate ganglion after chorda tympani injury
TSUZUKI Kenzo; YASUNO Hiroki; NOGUCHI Koichi; SAKAGAMI Masafumi
The Japanese journal of taste and smell research, 01 Dec. 1999 - The effect of neurotrophic factor on the rat olfactory receptor neurons following axotomy
YASUNO Hiroki; FUKAZAWA Keijirou; FUJII Megumi; TSUZUKI Kenzou; NOGUCHI Koichi; SAKAGAMI Masafumi
The Japanese journal of taste and smell research, 01 Dec. 1999 - Chronic Pain and Gene Expression in Spinal Cord - Molecular Mechanism of Cancer Pain -
NOGUCHI Koichi
The Journal of the Japan Society of Pain Clinicians, 25 Oct. 1999 - Paradoxical effect of L-Arginine on nitric oxide(NO) synthesis and histopathological changes in 5/6 nephrectomized SD rats.
TANAKA Toshihiko; NAKANISHI Takeshi; HASUIKE Yukiko; INOUE Touru; NOGUCHI Kouichi; TAKAMITSU Yoshihiro
Jpn J Nephrol, 1999 - EXPRESSIONS OF NEUROTRANSMITTERS IN GENICULATE GANGLION DUE TO ISCHEMIC FACIAL NERVE PARALYSIS : THE SECOND REPORT
MOHRI Daisuke; SATOMI Fumio; NOGUCHI Koichi; SAKAGAMI Masafumi
Facial nerve research, 10 Dec. 1998 - The increase in CGRP and PPT mRNA in ipsilateral L4 DRG in Chung model rats and its mechanism
FUKUOKA Testuo; TOKUNAGA Atsushi; KONDO Eiji; NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 05 Dec. 1998 - Distribution of N-type Voltage Gated Calcium Ion Channel in the rat dorsal root ganglion and spinal cord
KONDO Eiji; TOKUNAGA Atsushi; FUKUOKA Tetsuo; NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 05 Dec. 1998 - Effect of α2-adrenoceptor agonist & antagonist on dynorphin mRNA expression in dorsal horn neurons in a rat model of peripheral inflammation
SHIMODE N.; TASHIRO C.; TOKUNAGA A.; FUKUOKA T.; NOGUCHI K.
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 05 Dec. 1998 - Effect of electroacupuncture on the pain behavior and c-fos expression in spinal cord neurons in a rat neuropathic pain model
DAI Yi; NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 05 Dec. 1998 - Regulation of excitability of spinal cord and gracile nucleus neurons in the chronically injured sciatic nerve
TOKUNAGA A.; MIKI K.; FUKUOKA T.; NOGUCHI K.
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 05 Dec. 1998 - Expression of neuropeptide while regeneration of rats' olfactory receptor neurouns after axotomy
YASUNO Hiroki; FUKAZAWA Keijirou; FUJII Emi; NOGUCHI Koichi; SAKAGAMI Masashi
The Japanese journal of taste and smell research, 01 Dec. 1998 - 慢性痛と脊髄における遺伝子発現の変化
野口光一
The journal of the Japan Society of Pain Clinicians = 日本ペインクリニック学会誌, 15 Jun. 1998 - 237 ラット肝阻血再灌流モデルにおけるエンドセリンレセプターの局在ならびに発現動態(第52回日本消化器外科学会総会)
伊東通裕; 山中若樹; 安井智明; 黒田暢一; 田中恒雄; 田中渉; 山中潤一; 今北正道; 岡田敏弘; 岡本英三; 野口光一
日本消化器外科学会雑誌, 01 Jun. 1998 - ラット肝阻血再潅流モデルにおけるエンドセリン-1、エンドセリンレセプターの局在ならびに発現動態
伊東通裕; 山中若樹; 安井智明; 田中恒雄; 田中渉; 山中潤一; 黒田暢一; 今北正道; 岡田敏弘; 岡本英三; 野口光一
日本外科学会雑誌, 10 Mar. 1998 - CHANGES OF NEUROPEPTIDES IN TASTE BUDS DUE TO ISCHEMIC FACIAL NERVE PARALYSIS
MOHRI Daisuke; SATOMI Fumio; NODE Michiko; NOGUCHI Koichi; SAKAGAMI Masafumi
Facial nerve research, 10 Dec. 1997 - Effect of dorsal column lesion on thalamic nociceptive neuronal activity in rats with experimental mononeuropathy
MIKI K; IWATA K; TSUBOI Y; SUMINO R; NOGUCHI K
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 06 Dec. 1997 - Potential mechanisms for hypersensitivity in Chung model ; The increasc in neuropeptidecontaining fibers in L4 spinal cord and CGRP mRNA in L4 DRG.
FUKUOKA Tetuo; MIKI Kenji; TACHIBANA Toshiya; TOKUNAGA Atsushi; NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 06 Dec. 1997 - Effect of inhalation anesthetics on dynorphin mRNA expression in spinal cord after noxious stimulus
TANIMOTO M; TASHIRO C; TOKUNAGA A; FUKUOKA T; NOGUCHI K
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 06 Dec. 1997 - Effect of Oren-gedoku-to on neuropeptides' expression in rat model of peripheral inflammation
DAI Y; MIKI K; TOKUNAGA A; NOGUCHI K
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 06 Dec. 1997 - Histamine stimulation changes the Neuropsin in the Skin
KONDO Eiji; MIZUNO Makoto; MISHIMURA Mitsuhiro; TOHYAMA Masaya; SHIOSAKA Sadao; NOGUCHI Kohichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 06 Dec. 1997 - Effects of a novel analgesic compound OT-7100 on hyperalgesia in an animal model of neuropathic pain
YASUDA Tsuneo; IWAMOTO Takeshi; OHARA Masayuki; SATO Seiji; KOHRI Hideaki; NOGUCHI Koichi; SENBA Emiko
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 06 Dec. 1997 - Regeneration of olfactory receptor cell after transection of fila olfactolia
YASUNO Hiroki; FUKAZAWA Keijiro; NOGUCHI Kouichi; SAKAGAMI Masashi
The Japanese journal of taste and smell research, 01 Dec. 1997 - Electrophysiolpgical properties of dorsal column nucleus neurons in a rat model of peripheral mononeuropathy
MIKI K; IWATA K; TSUBOI Y; SUMINO R; NOGUCHI K
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 07 Dec. 1996 - Prodynorphin Gene Expression in Dorsal Horn Neurons Following Spinal Cord Injury
TACHIBANA T.
日本整形外科學會雜誌 = The Journal of the Japanese Orthopaedic Association, 25 Aug. 1996 - CGRP expression in a subpopulation of DRG neurons projecting to the gracile nucleus after peripheral nerve injury
MIKI Kenji; FUKUOKA Tetsuo; NOGUCHI Koichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, 02 Dec. 1995 - Request of Donations for the Hanshin-Awaji Great Earthquake
UCHINO S.; YAMADORI T.; NOGUCHI K.
解剖學雜誌, 01 Aug. 1995
Affiliated academic society
Research Themes
- Regulation of activation switching in spinal microglia as a tool of treatment of chronic pain
Grant-in-Aid for Challenging Research (Exploratory)
Hyogo College of Medicine
30 Jun. 2017 - 31 Mar. 2020 - Aberrant axo-axonic synaptic reorganization in the calcium channel subunit alpha2 delta-1/L1-CAM-containing central terminals of injured c-fibers in the spinal cord of a neuropathic pain model
Grant-in-Aid for Scientific Research (B)
Hyogo College of Medicine
01 Apr. 2017 - 31 Mar. 2020 - New mechanisms of neuropathic pain after spinal cord injury
Grant-in-Aid for Challenging Exploratory Research
Hyogo College of Medicine
01 Apr. 2015 - 31 Mar. 2017 - Development of minimally invasive treatment for osteoarthritis using focused ultrasound technique
Grant-in-Aid for Challenging Exploratory Research
Aichi Medical University
01 Apr. 2015 - 31 Mar. 2017 - pain modulation by AMP kinase through TRP channels and its molecular mechanism
Grant-in-Aid for Scientific Research (C)
Hyogo University of Health Sciences
01 Apr. 2014 - 31 Mar. 2017 - Molecular basis of spinal glia/endothelium/neurons interaction as the mechanisms of development and maintenance of chronic pain
Grant-in-Aid for Scientific Research (B)
Hyogo College of Medicine
01 Apr. 2013 - 31 Mar. 2016 - Novel regulator of gene expression in DRG in a neuropathic pain
Grant-in-Aid for Challenging Exploratory Research
Hyogo College of Medicine
01 Apr. 2012 - 31 Mar. 2014 - Molecular mechanisms of spinal neuro-glial interaction involving neuropathic pain
Grant-in-Aid for Scientific Research (B)
Hyogo College of Medicine
2010 - 2012 - Molecular mechanisms of neuropathic pain
Grant-in-Aid for Scientific Research (B)
Hyogo College of Medicine
2007 - 2009 - Role of MAP kinase family in the peripheral sensitization in a model of temporomandibular joint pain
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
2007 - 2008 - Contribution of extra-cellular protease, tPA to the radicular pain
Grant-in-Aid for Exploratory Research
Hyogo College of Medicine
2007 - 2008 - modulation mechanism of transient receptor potential A1 by proteinase activated receptor 2
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
2006 - 2007 - Alteration of the cell adhesion molecule L1 expression in a specific subset of primary afferent neurons contributes to neuropathic pain
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
2006 - 2007 - Role of inflammation on neuropathic pain in trigeminal nerve
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
2005 - 2006 - Contribution of thermo-sensitive ion channels to pathomechanism of CRPS
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
2005 - 2006 - Signal transduction mechanisms in primary afferent neurons following pain transmission
Grant-in-Aid for Scientific Research (B)
Hyogo College of Medicine
2003 - 2006 - Mechanisms of ectopic orofacial pain following peripheral nerve injury.
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
2003 - 2004 - Involvement of immune system to the inferior alveolar nerve injury.
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
2001 - 2002 - REGULATION OF GENE EXPRESSION AND NEUROFUNCTION UNDER OROFACIAL PAIN
Grant-in-Aid for Scientific Research (C)
兵庫医科大学->松本歯科大学
2000 - 2001 - MOLECULAR MECHANISM OF ABNORMAL SENSATION AFTER INJURY OF INFERIOR ALVEOLAR NERVE
Grant-in-Aid for Scientific Research (C)
HYOGO COLLEGE OF MEDICINE
1999 - 2000 - The mechanism of neuropatic pain model
Grant-in-Aid for Scientific Research (B).
HYOGO COLLEGE OF MEDICINE
1999 - 2000 - Expression of nerve construction protein in developing and regenerating auditory organ
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
1998 - 2000 - Changes in neuroactive substances in trigeminal motor nucleus after peripheral nerve injury
Grant-in-Aid for Scientific Research (C)
HYOGO COLLEGE OF MEDICINE
1996 - 1997 - Changes in gene expression in facial nerve nuclei in the rat model of ischemic Bell's palsy
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
1996 - 1997 - Dynorphin mRNA expression in dorsal horn neurons following traumatic spinal cord injury and the effect of neurotrophic factor
Grant-in-Aid for Scientific Research (C)
HYOGO COLLEGE OF MEDICINE
1996 - 1997 - Electron microsopic and histochemical study on the neural circuitry for color vision in the monkey retina
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
1995 - 1996 - Changes in neuroactive substances in a rat model of neuropathic pain and the role of hyperexcitability in neurons of spinal cord-dorsal colum-thalamus pathway
Grant-in-Aid for Scientific Research (B)
HYOGO COLLEGE OF MEDICINE
1995 - 1996 - The development of viral vector for in vivo gene-delivery and its applications
Grant-in-Aid for Developmental Scientific Research (B)
Wakayama Medical College
1993 - 1995