Paper

• Anti-transferrin receptor 1 antibody reduces angiotensin II-induced vascular remodeling.
  Yoshiro Naito; Takeshi Tsujino; Tadashi Matsuura; Masanori Asakura; Tohru Masuyama; Masaharu Ishihara
  Journal of molecular and cellular cardiology, Jul. 2025
• Transferrin receptor 1 deficiency in smooth muscle cells attenuates vascular remodeling in hypertensive mice.
  Yoshiro Naito; Hisashi Sawada; Tetsuo Horimatsu; Masaki Ohmuraya; Masanori Asakura; Masaharu Ishihara
  Hypertension research : official journal of the Japanese Society of Hypertension, Jun. 2025
• Eplerenone, diabetes, and chronic kidney disease in patients hospitalized for acute heart failure: findings from the EARLIER trial.
  Masatake Kobayashi; Akira Yamashina; Kazuhiro Satomi; Masataka Watanabe; Ryu Takagi; Ayako Tezuka; Shin Ito; Masanori Asakura; Masafumi Kitakaze
  Cardiovascular diabetology, Mar. 2025
• Efficacy of tranilast in preventing exacerbating cardiac function and death from heart failure in muscular dystrophy patients with advanced-stage heart failure: a single-arm, open-label, multicenter study.
  Tsuyoshi Matsumura; Takayasu Fukudome; Yasufumi Motoyoshi; Akinori Nakamura; Satoshi Kuru; Kazuhiko Segawa; Ruriko Kitao; Chigusa Watanabe; Takuhisa Tamura; Toshiaki Takahashi; Hiroya Hashimoto; Masahiro Sekimizu; Akiko M Saito; Masanori Asakura; Koichi Kimura; Yuko Iwata
  Orphanet journal of rare diseases, Jan. 2025
• Averaged oxygen desaturation improves the prognostic value of the six-minute walk test in elderly patients with heart failure.
  Isamu Sunayama; Kyung-Duk Min; Yoshiyuki Orihara; Junichi Ohno; Yuki Matsumoto; Aika Daimon; Yuko Soyama; Eri Manabe; Makiko Oboshi; Kohei Azuma; Masataka Sugahara; Akiyo Eguchi; Yoshiro Naito; Shinichiro Suna; Masanori Asakura; Masaharu Ishihara
  American journal of physiology. Heart and circulatory physiology, Jan. 2025
• Rediscovery of the implication of albuminuria in heart failure: emerging classic index for cardiorenal interaction.
  Kyung-Duk Min; Yuki Matsumoto; Masanori Asakura; Masaharu Ishihara
  ESC heart failure, Dec. 2024
• Effect of eplerenone in acute heart failure using a win ratio approach.
  Masatake Kobayashi; Akira Yamashina; Kazuhiro Satomi; Ayako Tezuka; Kevin Duarte; Shin Ito; Masanori Asakura; Masafumi Kitakaze; Nicolas Girerd
  Clinical research in cardiology : official journal of the German Cardiac Society, Nov. 2024
• Adverse events associated with early initiation of Eplerenone in patients hospitalized for acute heart failure.
  Masatake Kobayashi; Akira Yamashina; Kazuhiro Satomi; Ayako Tezuka; Shin Ito; Masanori Asakura; Masafumi Kitakaze; João Pedro Ferreira
  International journal of cardiology, Nov. 2024
• Novel Noninvasive Index Combining Echocardiography and Computed Tomography for Screening for Pulmonary Hypertension in Patients With Systemic Sclerosis.
  Yoshiyuki Orihara; Kyung-Duk Min; Akiyo Eguchi; Yoshitaka Okuhara; Masanori Asakura; Masaharu Ishihara
  CJC open, Sep. 2024
• Cardiac sympathetic nerve activity trends after renal denervation in heart failure with preserved ejection fraction.
  Tatsuya Shiraki; Hiroya Mizuno; Takuya Kishi; Masanori Asakura; Hidetsugu Asanoi; Yoshio Yasumura; Yasushi Sakata
  ESC heart failure, Aug. 2024
• Reply to comments on association between the type of pacemaker and progression of tricuspid regurgitation.
  Yoshihiro Ohta; Akiko Goda; Aika Daimon; Eri Manabe; Kumiko Masai; Hideyuki Kishima; Takanao Mine; Masanori Asakura; Masaharu Ishihara
  Journal of medical ultrasonics (2001), Apr. 2024
• Hypoxia-inducible factor-prolyl hydroxylase inhibitor Roxadustat (FG-4592) reduces renal fibrosis in Dahl salt-sensitive rats.
  Yoshiro Naito; Seiki Yasumura; Keisuke Okuno; Masanori Asakura; Takeshi Tsujino; Tohru Masuyama; Masaharu Ishihara
  Journal of hypertension, Mar. 2024
• Nocturnal Hypertension and Left Ventricular Diastolic Dysfunction in Patients With Diabetes With the Absence of Heart Failure: Prospective Cohort HSCAA Study.
  Yonekazu Kidawara; Manabu Kadoya; Masataka Igeta; Akiko Morimoto; Akio Miyoshi; Miki Kakutani-Hatayama; Akinori Kanzaki; Kosuke Konishi; Yoshiki Kusunoki; Takashi Daimon; Masanori Asakura; Masaharu Ishihara; Hidenori Koyama
  Hypertension (Dallas, Tex. : 1979), Jan. 2024
• Impact of Cytokine Release Syndrome on Cardiac Function After Chimeric Antigen Receptor-T Cell Therapy.
  Isamu Sunayama; Kyung-Duk Min; Yoshiyuki Orihara; Makiko Oboshi; Satoshi Yoshihara; Kyoko Yoshihara; Hiroya Tamaki; Masahiro Teramoto; Koichi Nishimura; Akiyo Eguchi; Yoshiro Naito; Satoshi Higasa; Masanori Asakura; Masaharu Ishihara
  JACC. Asia, Dec. 2023
• DAPagliflozin for the attenuation of albuminuria in Patients with hEaRt failure and type 2 diabetes (DAPPER study): a multicentre, randomised, open-label, parallel-group, standard treatment-controlled trial.
  Fumiki Yoshihara; Miki Imazu; Ichiro Sakuma; Yukio Hiroi; Hisao Hara; Osamu Okazaki; Chizuru Ishiguro; Chisato Izumi; Teruo Noguchi; Toshihiko Shiraiwa; Norio Nishioka; Kenshi Fujii; Katsuomi Iwakura; Osamu Tomonaga; Koichi Kobayashi; Masahiro Takihata; Kazuhiko Yumoto; Hiroyuki Takase; Toshiharu Himi; Ikki Shimizu; Tsutomu Murakami; Kenji Wagatsuma; Katsuhiko Sato; Takeyuki Hiramatsu; Satoshi Akabame; Shiro Hata; Masanori Asakura; Takanori Kawabata; Katsuhiro Omae; Shin Ito; Masafumi Kitakaze
  EClinicalMedicine, Dec. 2023
• Reticulocyte hemoglobin equivalent is an easily applicable marker for detecting iron deficiency in patients with acute decompensated heart failure.
  Keisuke Okuno; Yoshiro Naito; Junichi Ohno; Isamu Sunayama; Yuki Matsumoto; Yuko Soyama; Makiko Oboshi; Eri Manabe; Kohei Azuma; Masataka Sugahara; Kyung-Duk Min; Masanori Asakura; Masaharu Ishihara
  American heart journal plus : cardiology research and practice, Nov. 2023
• Mean pulmonary artery pressure estimated by echocardiogram rapidly exceeds 20 mmHg from the normal range in patients with connective tissue disease.
  Yoshiyuki Orihara; Masanori Asakura; Kyung-Duk Min; Yuki Matsumoto; Isamu Sunayama; Koichi Nishimura; Akiyo Eguchi; Yoshitaka Okuhara; Masaharu Ishihara
  Heart and vessels, Sep. 2023
• Efficacy of azilsartan on left ventricular diastolic dysfunction compared with candesartan: J-TASTE randomized controlled trial.
  Shin Ito; Hiroyuki Takahama; Masanori Asakura; Yukio Abe; Masayoshi Ajioka; Toshihisa Anzai; Takuo Arikawa; Takaharu Hayashi; Yorihiko Higashino; Shinya Hiramitsu; Noriaki Iwahashi; Chisato Izumi; Kazuo Kimura; Koichiro Kinugawa; Hidetaka Kioka; Young-Jae Lim; Ken Matsuoka; Satoshi Matsuoka; Hirohiko Motoki; Sunao Nakamura; Takafumi Nakayama; Akihiro Nomura; Taishi Sasaoka; Shin Takiuchi; Shigeru Toyoda; Tomoya Ueda; Tetsuya Watanabe; Akira Yamada; Masayoshi Yamamoto; Takashi Sozu; Masafumi Kitakaze
  Scientific reports, Aug. 2023
• Effect of eplerenone on clinical stability of Japanese patients with acute heart failure.
  Masatake Kobayashi; João Pedro Ferreira; Yuya Matsue; Taishiro Chikamori; Shin Ito; Masanori Asakura; Akira Yamashina; Masafumi Kitakaze
  International journal of cardiology, Mar. 2023
• Impact of lipoprotein(a) levels on primary patency after endovascular therapy for femoropopliteal lesions.
  Koji Yanaka; Hirokuni Akahori; Takahiro Imanaka; Kojiro Miki; Nagataka Yoshihara; Toshio Kimura; Takamasa Tanaka; Masanori Asakura; Masaharu Ishihara
  Heart and vessels, Feb. 2023
• Plasma renin activity variation following admission predicts patient outcome in acute decompensated heart failure with reduced and mildly reduced ejection fraction.
  Kohei Azuma; Koichi Nishimura; Kyung-Duk Min; Kanae Takahashi; Yuki Matsumoto; Akiyo Eguchi; Yoshitaka Okuhara; Yoshiro Naito; Sinichiro Suna; Masanori Asakura; Masaharu Ishihara
  Heliyon, Feb. 2023
• The differences between conventional lead, thin lead, and leadless pacemakers regarding effects on tricuspid regurgitation in the early phase.
  Yoshihiro Ohta; Akiko Goda; Aika Daimon; Eri Manabe; Kumiko Masai; Hideyuki Kishima; Takanao Mine; Masanori Asakura; Masaharu Ishihara
  Journal of medical ultrasonics (2001), Jan. 2023
• Efficacy of Sodium-Glucose Cotransporter 2 Inhibitors on Outcomes After Catheter Ablation for Atrial Fibrillation.
  Hideyuki Kishima; Takanao Mine; Eiji Fukuhara; Ryo Kitagaki; Masanori Asakura; Masaharu Ishihara
  JACC. Clinical electrophysiology, Nov. 2022
• Evolocumab for prevention of microvascular dysfunction in patients undergoing percutaneous coronary intervention: the randomised, open-label EVOCATION trial.
  Masaharu Ishihara; Masanori Asakura; Kiyoshi Hibi; Kozo Okada; Wataru Shimizu; Hitoshi Takano; Satoru Suwa; Kenshi Fujii; Yasuo Okumura; Toshiaki Mano; Kenichi Tsujita; Masataka Igeta; Rika Okamoto; Shinichiro Suna
  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Oct. 2022
• Sleep Apnea and Physical Movement During Sleep, But Not Sleep Duration, Are Independently Associated With Progression of Left Ventricular Diastolic Dysfunction: Prospective Hyogo Sleep Cardio-Autonomic Atherosclerosis Cohort Study.
  Yonekazu Kidawara; Manabu Kadoya; Akiko Morimoto; Takashi Daimon; Miki Kakutani-Hatayama; Kae Kosaka-Hamamoto; Akio Miyoshi; Kosuke Konishi; Yoshiki Kusunoki; Takuhito Shoji; Akiko Goda; Masanori Asakura; Masaharu Ishihara; Hidenori Koyama
  Journal of the American Heart Association, Oct. 2022
• Clinical utility of reticulocyte hemoglobin equivalent in patients with heart failure.
  Saki Tahara; Yoshiro Naito; Keisuke Okuno; Seiki Yasumura; Tetsuo Horimatsu; Junichi Ohno; Isamu Sunayama; Yuki Matsumoto; Eri Manabe; Kumiko Masai; Kohei Azuma; Koichi Nishimura; Kyung-Duk Min; Akiko Goda; Masanori Asakura; Masaharu Ishihara
  Scientific reports, Aug. 2022
• Impact of lipoprotein (a) on long-term outcome after percutaneous coronary intervention in the era of new generation drug-eluting stents.
  Toshio Kimura; Hirokuni Akahori; Takamasa Tanaka; Koji Yanaka; Nagataka Yoshihara; Kojiro Miki; Takahiro Imanaka; Masanori Asakura; Masaharu Ishihara
  Journal of cardiology, Aug. 2022
• Urine albumin-to-creatinine ratio on admission predicts early rehospitalization in patients with acute decompensated heart failure.
  Yuki Matsumoto; Yoshiyuki Orihara; Masanori Asakura; Kyung-Duk Min; Yoshitaka Okuhara; Kohei Azuma; Koichi Nishimura; Isamu Sunayama; Kazunori Kashiwase; Yoshiro Naito; Akiko Goda; Masaharu Ishihara
  Heart and vessels, Jul. 2022
• Iron Deficiency Induces Heart Failure With Ectopic Cardiac Calcification in Mice With Metabolic Syndrome.
  Yoshiro Naito; Hisashi Sawada; Seiki Yasumura; Tetsuo Horimatsu; Keisuke Okuno; Saki Tahara; Koichi Nishimura; Masanori Asakura; Takeshi Tsujino; Tohru Masuyama; Masaharu Ishihara
  Circulation. Heart failure, Jul. 2022
• Successful withdrawal of catecholamine with ivabradine administration in catecholamine-dependent heart failure.
  Kohei Azuma; Masanori Asakura; Koichi Nishimura; Saki Tahara; Yuki Matsumoto; Eri Manabe; Kyung-Duk Min; Masaharu Ishihara
  Journal of cardiology cases, Jun. 2022
• Tranilast for advanced heart failure in patients with muscular dystrophy: a single-arm, open-label, multicenter study.
  Tsuyoshi Matsumura; Hiroya Hashimoto; Masahiro Sekimizu; Akiko M Saito; Yasufumi Motoyoshi; Akinori Nakamura; Satoshi Kuru; Takayasu Fukudome; Kazuhiko Segawa; Toshiaki Takahashi; Takuhisa Tamura; Tetsuo Komori; Chigusa Watanabe; Masanori Asakura; Koichi Kimura; Yuko Iwata
  Orphanet journal of rare diseases, May 2022
• Design and rationale of the EVOCATION trial: A prospective, randomized, exploratory study comparing the effect of evolocumab on coronary microvascular function after percutaneous coronary intervention in patients with stable coronary artery disease.
  Masanori Asakura; Kiyoshi Hibi; Wataru Shimizu; Kenshi Fujii; Satoru Suwa; Yasuo Okumura; Toshiaki Mano; Masataka Igeta; Rika Okamoto; Masaharu Ishihara
  Journal of cardiology, Jan. 2022
• Aortic plaque burden predicts vascular events in patients with cardiovascular disease: The EAST-NOGA study.
  Keisuke Kojima; Sei Komatsu; Tsunekazu Kakuta; Daisuke Fukamachi; Shigeki Kimura; Hiroyuki Fujii; Masayoshi Matsuura; Kazuoki Dai; Hiroshi Matsuoka; Yoshiharu Higuchi; Yasunori Ueda; Masanori Asakura; Chikao Yutani; Yasuo Okumura; John W Eikelboom; Atsushi Hirayama; Kazuhisa Kodama
  Journal of cardiology, Jan. 2022
• Severe acute heart failure during or following cytokine release syndrome after CAR T-cell therapy.
  Kyoko Yoshihara; Yoshiyuki Orihara; Tokiko Hoshiyama; Hiroya Tamaki; Isamu Sunayama; Ikuo Matsuda; Akinori Nishikawa; Tomoko Kumamoto; Mami Samori; Nobuto Utsunomiya; Kyung-Duk Min; Masanori Asakura; Seiichi Hirota; Masaharu Ishihara; Satoshi Higasa; Satoshi Yoshihara
  Leukemia research reports, 2022
• ASB2 is a novel E3 ligase of SMAD9 required for cardiogenesis.
  Kyung-Duk Min; Masanori Asakura; Manabu Shirai; Satoru Yamazaki; Shin Ito; Hai Ying Fu; Hiroshi Asanuma; Yoshihiro Asano; Tetsuo Minamino; Seiji Takashima; Masafumi Kitakaze
  Scientific reports, Nov. 2021