Last Updated :2024/09/11
Researcher Information
Field Of Study
Career
- Apr. 2024 - Present
Hyogo Medical University, Faculty of Medicine Department of Preventive Medicine, Professor and Chairman - Aug. 2018 - Mar. 2024
Hyogo College of Medicine, 環境予防医学講座, 准教授 - Apr. 2007 - Jul. 2018
Hyogo College of Medicine, 環境予防医学講座, 講師 - Apr. 2005 - Mar. 2007
Hyogo College of Medicine, 内科学講座（血液内科）, 助手 - Feb. 2003 - Mar. 2005
兵庫医科大学 総合内科 血栓止血老年病科助手 - May 2001 - Jan. 2003
Yamagata University, Faculty of Medicine
Research activity information
Paper
- Differences in serum and plasma levels of microRNAs and their time-course changes after blood collection.
Ichiro Wakabayashi; Mikio Marumo; Kazumi Ekawa; Takashi Daimon
Practical laboratory medicine, Mar. 2024 - Augmentation by resveratrol of the inhibitory effect of ethanol on platelet aggregation.
Kazumi Ekawa; Mikio Marumo; Ichiro Wakabayashi
Platelets, Dec. 2023, [Reviewed] - Evidence for Indoxyl Sulfate as an Inducer of Oxidative Stress in Patients With Diabetes
Ichiro Wakabayashi; Mikio Marumo
IN VIVO, Jul. 2022, [Reviewed] - Data on urinary pteridines as a discriminator of atherosclerotic risk in patients with diabetes.
Mikio Marumo; Kazumi Ekawa; Ichiro Wakabayashi
Data in brief, Apr. 2022, [Reviewed]
Lead - Urinary pteridines as a discriminator of atherosclerotic risk in patients with diabetes
Mikio Marumo; Kazumi Ekawa; Ichiro Wakabayashi
ATHEROSCLEROSIS PLUS, Dec. 2021, [Reviewed]
Lead - Relationship of urinary liver-type fatty acid-binding protein with cardiovascular risk factors in the Japanese population without chronic kidney disease: Sasayama study.
Yoshimi Kubota; Aya Higashiyama; Mikio Marumo; Masami Konishi; Yoshiko Yamashita; Tomonori Okamura; Yoshihiro Miyamoto; Ichiro Wakabayashi
BMC nephrology, May 2021, [Reviewed] - Resveratrol inhibits Ca2+ signals and aggregation of platelets.
Mikio Marumo; Kazumi Ekawa; Ichiro Wakabayashi
Environmental health and preventive medicine, Nov. 2020, [Reviewed]
Lead - Inverse association between habitual alcohol drinking and d-dimer in patients with type 2 diabetes mellitus
Marumo M; Ekawa K; Ebara S; Wakabayashi I
Alcohol Alcohol, Jul. 2019, [Reviewed]
Lead - Inhibition by Ethanol of Shear Stress-Induced Formation of Platelet Thrombi in Whole Blood.
Ekawa K; Marumo M; Wakabayashi I
Alcohol Alcohol, Nov. 2018, [Reviewed] - Cardiometabolic index as a useful discriminator for the risk of increased arterial stiffness.
Ichiro Wakabayashi; Mikio Marumo; Yoshimi Kubota; Aya Higashiyama; Yoshihiro Miyamoto; Tomonori Okamura
Clinica chimica acta; international journal of clinical chemistry, Nov. 2018, [Reviewed] - Relationships of Age and Gender with Ankle-brachial Systolic Pressure Index and Cardio-ankle Vascular Index in Patients with Diabetes Mellitus
Mikio Marumo; Shigeyuki Ebara; Ikumi Nishibe; Jun-ichi Soneda; Ichiro Wakabayashi
International Journal of Gerontology, Mar. 2018, [Reviewed]
Lead - Relationships of oxidized HDL with blood coagulation and fibrinolysis in patients with type 2 diabetes mellitus
Shigeyuki Ebara; Mikio Marumo; Jun Mukai; Makoto Ohki; Kagehiro Uchida; Ichiro Wakabayashi
Journal of Thrombosis and Thrombolysis, Feb. 2018, [Reviewed] - Effects of methanol and formic acid on human platelet aggregation
Mikio Marumo; Ichiro Wakabayashi
Environmental Health and Preventive Medicine, Dec. 2017, [Reviewed]
Lead - Detection of Subclinical Peripheral Artery Ischemia in Healthy Male Smokers by an Ankle-Brachial Index After Exercise: Sasayama Study
Yoshimi Kubota; Aya Higashiyama; Mikio Marumo; Masami Konishi; Yoshiko Yamashita; Chikara Tashiro; Tomonori Okamura; Yoshihiro Miyamoto; Ichiro Wakabayashi
ANGIOLOGY, Oct. 2017, [Reviewed] - Cysteinylated transthyretin as a discriminator of cardiovascular risk in patients with diabetes mellitus
Ichiro Wakabayashi; Mikio Marumo; Daisuke Nonaka; Lyang-Ja Lee; Jun Mukai; Makoto Ohki; Kenji Tanaka; Kagehiro Uchida
CLINICA CHIMICA ACTA, Jul. 2017, [Reviewed] - Inverse associations of HDL cholesterol and oxidized HDL with d-dimer in patients with type 2 diabetes mellitus
Shigeyuki Ebara; Mikio Marumo; Chika Yamabata; Ikumi Nishibe; Jun-ichi Soneda; Jun Mukai; Makoto Ohki; Kagehiro Uchida; Ichiro Wakabayashi
THROMBOSIS RESEARCH, Jul. 2017, [Reviewed] - Selective induction of anti-inflammatory monocyte-platelet aggregates in a model of pulsatile blood flow at low shear rates
Yuji Takeda; Mikio Marumo; Hidetoshi Nara; Zhong-Gang Feng; Hironobu Asao; Ichiro Wakabayashi
PLATELETS, Sep. 2016, [Reviewed] - Potential Biomarker Peptides Associated with Acute Alcohol-Induced Reduction of Blood Pressure
Ichiro Wakabayashi; Mikio Marumo; Daisuke Nonaka; Tomoko Shimomura; Ryoji Eguchi; Lyang-Ja Lee; Kenji Tanaka; Katsuhiko Hatake
PLOS ONE, Jan. 2016, [Reviewed] - Association Between Serum Long-Chain n-3 and n-6 Polyunsaturated Fatty Acid Profiles and Glomerular Filtration Rate Assessed by Serum Creatinine and Cystatin C Levels in Japanese Community-Dwellers
Aya Higashiyama; Yoshimi Kubota; Mikio Marumo; Masami Konishi; Yoshiko Yamashita; Kunihiro Nishimura; Yoshihiro Fukuda; Tomonori Okamura; Ichiro Wakabayashi
JOURNAL OF EPIDEMIOLOGY, Apr. 2015, [Reviewed] - Ethanol-Induced Inhibition of Platelet Aggregation in Whole Blood from Healthy Donors
Marumo M; Wakabayashi I
J Clin Toxicol, 2015, [Reviewed]
Lead - Hairy cell leukemia accompanied by Evans syndrome.
Ebara S; Kagosima M; Marumo M; Ito Y; Tatumi E; Mitsutani S
[Rinsho ketsueki] The Japanese journal of clinical hematology, Apr. 2014, [Reviewed] - Inhibition of thrombin-induced Ca2+ influx in platelets by R59949, an inhibitor of diacylglycerol kinase
Mikio Marumo; Tomoyuki Nakano; Yuji Takeda; Kaoru Goto; Ichiro Wakabayashi
JOURNAL OF PHARMACY AND PHARMACOLOGY, Jun. 2012, [Reviewed]
Lead - Attenuated phagocytic activity of monocytes in type 2 diabetic Goto-Kakizaki rats
Yuji Takeda; Mikio Marumo; Ichiro Wakabayashi
IMMUNOBIOLOGY, Oct. 2011, [Reviewed] - Diverse effects of ethanol on Ca2+ entry and subsequent aggregation of platelets
Mikio Marumo; Ichiro Wakabayashi
ALCOHOL, Jun. 2010, [Reviewed]
Lead - Sensitivity of thrombin-induced platelet aggregation to inhibition by ethanol.
Mikio Marumo; Ichiro Wakabayashi
Clinica chimica acta; international journal of clinical chemistry, Apr. 2009, [Reviewed]
Lead - TRPC4 expression determines sensitivity of the platelet-type capacitative Ca2+ entry channel to intracellular alkalosis.
Ichiro Wakabayashi; Mikio Marumo; Annarita Graziani; Michael Poteser; Klaus Groschner
Platelets, Nov. 2006, [Reviewed] - [Effects of ethanol ingestion on glucose tolerance in people with different genotypes of ALDH2].
Negoro M; Marumo M; Takahashi Y; Wakabayashi I
Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence, Oct. 2005, [Reviewed] - Monensin augments capacitative Ca2+ entry and subsequent aggregation of platelets via an intracellular alkalosis-mediated mechanism.
Mikio Marumo; Ichiro Wakabayashi
Pharmacological research, Feb. 2005, [Reviewed]
Lead - Intracellular alkalinization augments capacitative Ca2+ entry in platelets.
Mikio Marumo; Ichiro Wakabayashi
Thrombosis and haemostasis, Dec. 2003, [Reviewed]
Lead - Intracellular alkalinization augments capacitative Ca2+ entry in vascular smooth muscle cells
K Wakabayashi; M Marumo; Y Sotoda
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, Jun. 2003, [Reviewed] - Diverse effects of monensin on capacitative Ca2+ entry and release of stored Ca2+ in vascular smooth muscle cells
Wakabayashi, I; M Marumo; Y Sotoda
EUROPEAN JOURNAL OF PHARMACOLOGY, Mar. 2003, [Reviewed] - Intracellular alkalinization augments platelet aggregation due to increase in cytosolic free-Ca2+.
Mikio Marumo; Akira Suehiro; Eizo Kakishita; Ichiro Wakabayashi
Platelets, May 2002, [Reviewed]
Lead - Ethanol inhibits store-operated Ca2+ entry of platelets.
Ichiro Wakabayashi; Mikio Marumo
Pharmacology & toxicology, Apr. 2002, [Reviewed] - Extracellular pH affects platelet aggregation associated with modulation of store-operated Ca2+ entry
Mikio Marumo; Akira Suehiro; Eizo Kakishita; Klaus Groschner; Ichiro Wakabayashi
Thrombosis Research, Dec. 2001, [Reviewed]
Lead - In vitro inhibitory effect of sarpogrelate hydrochloride on serotonin- induced platelet small-aggregate formation
Akira Suehiro; Mikio Marumo; Hiroshi Yoshimoto; Satoshi Higasa; Eizo Kakishita
Current Therapeutic Research - Clinical and Experimental, Feb. 2000 - Effect of tissue-type plasminogen activator on platelet aggregation
A Suehiro; H Tsujioka; M Marumo; H Yoshimoto; S Higasa; E Kakishita
RECENT PROGRESS IN BLOOD COAGULATION AND FIBRINOLYSIS, 1997, [Reviewed]
MISC
- 血小板凝集およびカルシウム流入機構への1-ブタノールの影響
江川 可純; 丸茂 幹雄; 若林 一郎
アルコールと医学生物学, Apr. 2018 - 血小板の異なるメカニズムを介するカルシウム流入および凝集能へのレスベラトロールの作用
丸茂 幹雄; 若林 一郎
アルコールと医学生物学, Jun. 2016 - アルコール性肝硬変患者における腹水濾過濃縮還元療法(CART)による腹水管理
江原 重幸; 篭島 瑞穂; 山田 直人; 梅田 茉友; 岡本 圭司; 丸茂 幹雄; 若林 一郎
アルコールと医学生物学, Mar. 2015 - 血小板のカルシウム流入および凝集能への異なった種類のアルコールによる影響
丸茂 幹雄; 若林 一郎
アルコールと医学生物学, Mar. 2015 - 全血中での血小板凝集へのエタノールの抑制作用
丸茂 幹雄; 丸茂 久美子; 若林 一郎
アルコールと医学生物学, Jan. 2014 - 血小板のカルシウム流入および凝集能へのアルコール類の作用
丸茂 幹雄; 丸茂 久美子; 若林 一郎
アルコールと医学生物学, Oct. 2012 - EFFECTS OF ALCOHOL ON Ca2+ ENTRY AND SUBSEQUENT AGGREGATION OF PLATELETS THROUGH DIFFERENT PATHWAYS
M. Marumo; I. Wakabayashi
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, Sep. 2012 - EFFECTS OF ALCOHOL ON Ca2+ ENTRY AND SUBSEQUENT AGGREGATION OF PLATELETS THROUGH DIFFERENT PATHWAYS
M. Marumo; I. Wakabayashi
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, Sep. 2012 - エタノールの血小板抑制作用に関する異なった測定法による評価
丸茂 幹雄; 丸茂 久美子; 若林 一郎
アルコールと医学生物学, Apr. 2011 - 血小板の凝集及びカルシウム流入機構へのアルコールの作用
丸茂 幹雄; 丸茂 久美子; 若林 一郎
アルコールと医学生物学, Mar. 2009 - Effects of alcohol on platelet aggregation and calcium entry
MARUMO Mikio; WAKABAYASHI Ichiro
日本アルコール・薬物医学会雑誌 = Japanese journal of alcohol studies & drug dependence, 28 Aug. 2008 - TRPC4 expression determines sensitivity of the platelet-type capacitative Ca2+ entry channel to intracellular alkalosis
I. Wakabayashi; M. Marumo; A. Graziani; M. Poteser; K. Groschner
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, Mar. 2007 - Intracellular pH and calcium homeostasis in regulation of platelet and vascular cell function
WAKABAYASHI Ichiro; MARUMO Mikio; KAKISHITA Eizo
Blood & Vessel, 2005 - 血小板の容量依存性カルシウム流入へのモネンシンおよびEIPAの効果と細胞内アルカリ化の意義
丸茂幹雄; 垣下榮三; 若林一郎
東北止血血栓研究会誌, 2004 - TTP, HUS, TMAとは
血液・腫瘍科, 2004 - Intracellular alkalinization augments capacitative Ca2+ entry in vascular smooth muscle cells
K Wakabayashi; M Marumo; Y Sotoda
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, Jun. 2003 - Diverse effects of monensin on capacitative Ca2+ entry and release of stored Ca2+ in vascular smooth muscle cells
Wakabayashi, I; M Marumo; Y Sotoda
EUROPEAN JOURNAL OF PHARMACOLOGY, Mar. 2003 - 血小板および巨核球の容量依存性カルシウム流入に及ぼす細胞内アルカリ化の影響
東北止血血栓研究会誌, 2003 - Ethanol inhibits store-operated Ca2+ entry of platelets.
Ichiro Wakabayashi; Mikio Marumo
Pharmacology & toxicology, Apr. 2002 - Development of "Medication Support Sheet" for Effective Antiretroviral Therapy.
HIGASA Satoshi; SUEHIRO Akira; SAWADA Akihiro; HASEGAWA Yoshikazu; MARUMO Mikio; KAKISHITA Eizo
The Journal of AIDS Research, 1999 - Role of nitric oxide (NO) on whole blood aggregation measured by impedance aggregometer
H Yoshimoto; A Suehiro; M Marumo; T Matsuda; S Higasa; E Kakishita
THROMBOSIS AND HAEMOSTASIS, Jun. 1997 - Effect of plasminogen activator on the activation of coagulation factor VII
H Tsujioka; A Suehiro; M Marumo; S Higasa; M Ueda; E Kakishita
THROMBOSIS AND HAEMOSTASIS, Jun. 1997 - Urgent Allogeneic Bone Marrow Transplantation Using a Preparative Regimen of Cyclophosphamide Anti-Human Thymocytes Rabbit Globulin in a Patient with Severe aplastic Anemia with Pneumonia
OKAMOTO Takahiro; MARUMO Mikio; SAHEKI Kaname; OKADA Masaya; KAWAGUCHI Kohtaro; TAKATUKA Hiroyuki; FUJIMORI Yoshihiro; TAKEMOTO Yoshinobu; KOHSAKI Yoshihiro; KANAMARU Akihisa; KAKISHITA Eizo
臨床血液, 1996 - In a case of severe aplastic animia with severe pneumonia, allogenic bone marrow transplantation was successfully done by using granulocyte transfusion together
MARUMO Mikio; OKAMOTO Takahiro; SAEKI Kaname; TAKATSUKA Hiroyuki; FUJIMORI Yoshihiro; TAKEMOTO Yoshinobu; KOHSAKI Masatoshi; KANAMARU Akihisa; KAKISHITA Eizo; NAGAI Kiyoyasu
無菌生物 = Japanese journal of germfree life and gnotobiology, Jun. 1995
Books and other publications
Research Themes
- New peptide biomarkers for prevention and mechanistic investigation of alcohol-induced hypertension
Grant-in-Aid for Scientific Research (B)
Hyogo Medical University
01 Apr. 2021 - 31 Mar. 2024 - Elucidation of sex difference in the association of alcohol drinking pattern with blood coagulant and fibrinolytic function as risk factor of atherosclerosis.
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2018 - 31 Mar. 2021 - Inhibitory effects of polyphenols on the TRP channel-mediated pathways in human platelets
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2018 - 31 Mar. 2021 - Development of useful biomarkers for diagnosis of septic shock by using a new method for peptidome analysis
Grant-in-Aid for Challenging Exploratory Research
Hyogo College of Medicine
01 Apr. 2014 - 31 Mar. 2017 - An epidemiological study on peripheral arterial disease using a new instrument for measuring blood pressure and pulse wave
Grant-in-Aid for Scientific Research (B)
Hyogo College of Medicine
01 Apr. 2012 - 31 Mar. 2016 - Research in substances inducing changes in blood pressure after alcohol drinking by using a new method for peptidome analysis
Grant-in-Aid for Challenging Exploratory Research
Hyogo College of Medicine
01 Apr. 2012 - 31 Mar. 2014 - Establishment of arteriosclerosis index related with leukocyte and platelet function measured by whole blood analysis method
Grant-in-Aid for Scientific Research (C)
2010 - 2012 - Molecular mechanism for anti-thrombotic action of alcohol drinking related to TRP channels of platelets.
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
2010 - 2012 - An epidemiological study on the association between habitual alcohol drinking and risk factors for atherosclerotic disease in the elderly
Grant-in-Aid for Scientific Research (B)
Hyogo College of Medicine
2009 - 2011 - Study on alcohol consumption that is recommended to restrict from the viewpoint of prevention of atherosclerotic disease in women
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
2007 - 2008 - 血小板のアルカリ化に対する影響についての検討.
- Enhancing Effect of Cytoplasmic Alkalinization of Human Platelets Activation.
