Last Updated :2024/12/13
Researcher Information
Degree
Educational Background
- 2001, University of Occupational and Environmental Health, Japan, 医学系研究科, 生体適応系
- 2001, University of Occupational and Environmental Health, Japan, Graduate School, Division of Medicine
- 1997, Hiroshima University, 医学研究科, 博士課程前期
- 1995, Kyushu Institute of Technology, School of Computer Science and Systems Engineering, 生物・化学システム工学科
- 1995, Kyushu Institute of Technology, Faculty of Computer Science and Systems Engineering
Research activity information
Award
- Jun. 2017
第66回日本アレルギー学会学術大会, English session Best presentation award
黒田 悦史 - Dec. 2016
第45回日本免疫学会学術集会, Best presentation award
黒田 悦史 - Sep. 2015
日本免疫毒性学会, 奨励賞
黒田 悦史 - May 2015
第64回日本アレルギー学会学術大会, English session Best presentation award
黒田 悦史 - Sep. 2010
第17回日本免疫毒性学会学術大会, 年会長賞
黒田 悦史 - Jun. 2010
第75回日本インターフェロン・サイトカイン学会学術集会, 優秀ポスター賞
黒田 悦史 - Oct. 2006
第24回産業医科大学学会, 優秀ポスター賞
黒田 悦史 - Oct. 2000
第18回産業医科大学学会, 学会長賞
Japan
Paper
- Bisphenol A triggers activation of ocular immune system and aggravates allergic airway inflammation
Tatsuo Ueda; Takumi Adachi; Tomoya Hayashi; Koubun Yasuda; Kazufumi Matsushita; Eiko Koike; Rie Yanagisawa; Takahiro Nagatake; Jun Kunisawa; Ken J. Ishii; Kenzo Tsuzuki; Etsushi Kuroda
Clinical Immunology, Nov. 2024 - A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages
Izumi Sasaki; Yuri Fukuda-Ohta; Chihiro Nakai; Naoko Wakaki-Nishiyama; Chizuyo Okamoto; Daisuke Okuzaki; Shuhei Morita; Shiori Kaji; Yuki Furuta; Hiroaki Hemmi; Takashi Kato; Asumi Yamamoto; Emi Tosuji; Shin-Ichiroh Saitoh; Takashi Tanaka; Katsuaki Hoshino; Shinji Fukuda; Kensuke Miyake; Etsushi Kuroda; Ken J. Ishii; Takao Iwawaki; Koichi Furukawa; Tsuneyasu Kaisho
Cell Reports, Apr. 2024 - RAGE in circulating immune cells is fundamental for hippocampal inflammation and cognitive decline in a mouse model of latent chronic inflammation.
Dasen Ye; Akio Miyoshi; Tomoe Ushitani; Manabu Kadoya; Masataka Igeta; Kosuke Konishi; Takuhito Shoji; Koubun Yasuda; Shiho Kitaoka; Hideshi Yagi; Etsushi Kuroda; Yasuhiko Yamamoto; Jidong Cheng; Hidenori Koyama
Brain, behavior, and immunity, Feb. 2024 - 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a partial STING agonist, competes for human STING activation.
Burcu Temizoz; Takayuki Shibahara; Kou Hioki; Tomoya Hayashi; Kouji Kobiyama; Michelle Sue Jann Lee; Naz Surucu; Erdal Sag; Atsushi Kumanogoh; Masahiro Yamamoto; Mayda Gursel; Seza Ozen; Etsushi Kuroda; Cevayir Coban; Ken J Ishii
Frontiers in immunology, 2024 - A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages
Izumi Sasaki; Yuri Fukuda-Ohta; Chihiro Nakai; Naoko Wakaki-Nishiyama; Chizuyo Okamoto; Takashi Orimo; Daisuke Okuzaki; Shuhei Morita; Shiori Kaji; Yuki Furuta; Hiroaki Hemmi; Takashi Kato; Asumi Yamamoto; Takashi Tanaka; Katsuaki Hoshino; Shinji Fukuda; Kensuke Miyake; Etsushi Kuroda; Ken J Ishii; Takao Iwawaki; Koichi Furukawa; Tsuneyasu Kaisho
bioRxiv, Jul. 2023 - RAGEは潜在性慢性炎症を伴うメタボリックシンドロームモデルマウスにおける認知障害に関与する(RAGE is involved in cognitive impairment in a mouse model of metabolic syndrome with latent chronic inflammation)
叶 大森; 三好 晶雄; 牛谷 友栄; 角谷 学; 小西 康輔; 庄司 拓仁; 安田 好文; 北岡 志保; 八木 秀司; 黒田 悦史; 山本 靖彦; 小山 英則
糖尿病, Apr. 2023 - Alveolar macrophages instruct CD8+ T cell expansion by antigen cross-presentation in lung.
Takumi Kawasaki; Moe Ikegawa; Kosuke Yunoki; Hifumi Otani; Daisuke Ori; Ken J Ishii; Etsushi Kuroda; Shiki Takamura; Masahiro Kitabatake; Toshihiro Ito; Ayako Isotani; Taro Kawai
Cell reports, Dec. 2022 - 終末糖化産物受容体(RAGE)は慢性炎症メタボリックシンドロームモデルでの認知機能障害に関与する
三好 晶雄; 叶 大森; 牛谷 友栄; 角谷 学; 小西 康輔; 庄司 拓仁; 安田 好文; 黒田 悦史; 北岡 志保; 八木 秀司; 山本 靖彦; 小山 英則
肥満研究, Nov. 2022 - Efficient antigen delivery by dendritic cell-targeting peptide via nucleolin confers superior vaccine effects in mice
Teppei Matsuda; Kazuki Misato; Shigeyuki Tamiya; Yasuhiro Akeda; Ikuhiko Nakase; Etsushi Kuroda; Shokichi Takahama; Motohiro Nonaka; Takuya Yamamoto; Michiko N. Fukuda; Yasuo Yoshioka
iScience, Nov. 2022 - ケミカルメディエーター、受容体 スギ花粉症に対するTLR9アゴニストを用いた新規皮下免疫療法薬の効果
土井 雅津代; 内海 大知; 鈴木 啓介; 黒田 悦史; 石井 健
アレルギー, Aug. 2022 - Safety and immunogenicity of a quadrivalent seasonal influenza vaccine adjuvanted with hydroxypropyl-β-cyclodextrin: A phase 1 clinical trial.
Akane Watanabe; Sumiyuki Nishida; Temizöz Burcu; Takayuki Shibahara; Takato Kusakabe; Etsushi Kuroda; Ken J Ishii; Atsushi Kumanogoh
Vaccine, Jul. 2022, [Reviewed] - CpG ODN (K3)-toll-like receptor 9 agonist-induces Th1-type immune response and enhances cytotoxic activity in advanced lung cancer patients: a phase I study.
Tomoyuki Otsuka; Sumiyuki Nishida; Takayuki Shibahara; Burcu Temizoz; Masanari Hamaguchi; Takayuki Shiroyama; Keiko Kimura; Kotaro Miyake; Haruhiko Hirata; Yumiko Mizuno; Mayu Yagita; Yusuke Manabe; Etsushi Kuroda; Yoshito Takeda; Hiroshi Kida; Ken J Ishii; Atsushi Kumanogoh
BMC cancer, Jul. 2022 - Anti-tumor immunity by transcriptional synergy between TLR9 and STING activation.
Burcu Temizoz; Kou Hioki; Shingo Kobari; Nao Jounai; Takato Kusakabe; Michelle S J Lee; Cevayir Coban; Etsushi Kuroda; Ken J Ishii
International immunology, Apr. 2022 - Suppression of Airway Allergic Reactions by a Photocatalytic Filter Using Mouse Model
Taisuke Tomonaga; Hiroto Izumi; Chinatsu Nishida; Kaori Kato; Kazuhiro Yatera; Etsushi Kuroda; Yasuo Morimoto
Toxics, Jan. 2022 - Machine Learning-Assisted Screening of Herbal Medicine Extracts as Vaccine Adjuvants.
Kou Hioki; Tomoya Hayashi; Yayoi Natsume-Kitatani; Kouji Kobiyama; Burcu Temizoz; Hideo Negishi; Hitomi Kawakami; Hiroyuki Fuchino; Etsushi Kuroda; Cevayir Coban; Nobuo Kawahara; Ken J Ishii
Frontiers in immunology, 2022 - Neutrophil-Mediated Lung Injury Both via TLR2-Dependent Production of IL-1α and IL-12 p40, and TLR2-Independent CARDS Toxin after Mycoplasma pneumoniae Infection in Mice
Shigeyuki Tamiya; Eisuke Yoshikawa; Monami Ogura; Etsushi Kuroda; Koichiro Suzuki; Yasuo Yoshioka
Microbiology Spectrum, Dec. 2021 - Thymic stromal lymphopoietin contributes to protection of mice from Strongyloides venezuelensis infection by CD4+ T cell-dependent and -independent pathways.
Atsuhide Koida; Koubun Yasuda; Takumi Adachi; Kazufumi Matsushita; Makoto Yasuda; Shigeru Hirano; Etsushi Kuroda
Biochemical and biophysical research communications, May 2021 - Lung fibroblasts produce IL-33 in response to stimulation with retinoblastoma-binding protein 9 via production of prostaglandin E2.
Takumi Adachi; Koubun Yasuda; Taichiro Muto; Satoshi Serada; Tomohiro Yoshimoto; Ken J Ishii; Etsushi Kuroda; Kimi Araki; Masaki Ohmuraya; Tetsuji Naka; Kenji Nakanishi
International immunology, Sep. 2020 - Vaccination using inactivated Mycoplasma pneumoniae induces detrimental infiltration of neutrophils after subsequent infection in mice.
Shigeyuki Tamiya; Eisuke Yoshikawa; Monami Ogura; Etsushi Kuroda; Koichiro Suzuki; Yasuo Yoshioka
Vaccine, Jul. 2020 - Murine Cross-Reactive Nonneutralizing Polyclonal IgG1 Antibodies Induced by Influenza Vaccine Inhibit the Cross-Protective Effect of IgG2 against Heterologous Virus in Mice.
Meito Shibuya; Taiki Aoshi; Etsushi Kuroda; Yasuo Yoshioka
Journal of virology, Jun. 2020 - ZBP1 governs the inflammasome-independent IL-1α and neutrophil inflammation that play a dual role in anti-influenza virus immunity.
Masatoshi Momota; Patrick Lelliott; Atsuko Kubo; Takato Kusakabe; Kouji Kobiyama; Etsushi Kuroda; Yumiko Imai; Shizuo Akira; Cevayir Coban; Ken J Ishii
International immunology, Mar. 2020, [Reviewed] - Regnase-1 degradation is crucial for IL-33- and IL-25-mediated ILC2 activation.
Kazufumi Matsushita; Hiroki Tanaka; Koubun Yasuda; Takumi Adachi; Ayumi Fukuoka; Shoko Akasaki; Atsuhide Koida; Etsushi Kuroda; Shizuo Akira; Tomohiro Yoshimoto
JCI insight, Feb. 2020 - IL-33 Is Essential for Adjuvant Effect of Hydroxypropyl-β-Cyclodexrin on the Protective Intranasal Influenza Vaccination.
Shingo Kobari; Takato Kusakabe; Masatoshi Momota; Takayuki Shibahara; Tomoya Hayashi; Koji Ozasa; Hideaki Morita; Kenji Matsumoto; Hirohisa Saito; Shuichi Ito; Etsushi Kuroda; Ken J Ishii
Frontiers in immunology, 2020, [Reviewed] - Role of eosinophils in protective immunity against secondary nematode infections.
Koubun Yasuda; Etsushi Kuroda
Immunological medicine, Dec. 2019 - Cholera toxin B induces interleukin-1β production from resident peritoneal macrophages through the pyrin inflammasome as well as the NLRP3 inflammasome.
Takashi Orimo; Izumi Sasaki; Hiroaki Hemmi; Toshiya Ozasa; Yuri Fukuda-Ohta; Tomokazu Ohta; Mio Morinaka; Mariko Kitauchi; Takako Yamaguchi; Yayoi Sato; Takashi Tanaka; Katsuaki Hoshino; Kei-Ichi Katayama; Shinji Fukuda; Kensuke Miyake; Masahiro Yamamoto; Takashi Satoh; Koichi Furukawa; Etsushi Kuroda; Ken J Ishii; Kiyoshi Takeda; Tsuneyasu Kaisho
International immunology, Sep. 2019, [Reviewed] - B cell-intrinsic MyD88 signaling controls IFN-γ-mediated early IgG2c class switching in mice in response to a particulate adjuvant.
Michelle Sue Jann Lee; Yayoi Natsume-Kitatani; Burcu Temizoz; Yukiko Fujita; Aki Konishi; Kyoko Matsuda; Yoshikatsu Igari; Toshihiro Tsukui; Kouji Kobiyama; Etsushi Kuroda; Motoyasu Onishi; Thomas Marichal; Wataru Ise; Takeshi Inoue; Tomohiro Kurosaki; Kenji Mizuguchi; Shizuo Akira; Ken J Ishii; Cevayir Coban
European journal of immunology, Sep. 2019, [Reviewed] - BLT1 mediates commensal bacteria-dependent innate immune signals to enhance antigen-specific intestinal IgA responses.
Takahiro Nagatake; So-Ichiro Hirata; Tomoaki Koga; Etsushi Kuroda; Shingo Kobari; Hidehiko Suzuki; Koji Hosomi; Naomi Matsumoto; Yaulia Yanrismet; Michiko Shimojou; Sakiko Morimoto; Fumiyuki Sasaki; Ken J Ishii; Takehiko Yokomizo; Jun Kunisawa
Mucosal immunology, Sep. 2019, [Reviewed] - Rapid Quantification of NETs In Vitro and in Whole Blood Samples by Imaging Flow Cytometry.
Patrick M Lelliott; Masatoshi Momota; Michelle S J Lee; Etsushi Kuroda; Norifumi Iijima; Ken J Ishii; Cevayir Coban
Cytometry. Part A : the journal of the International Society for Analytical Cytology, May 2019, [Reviewed] - Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection.
Seiki Fujiwara; Midori Hoshizaki; Yu Ichida; Dennis Lex; Etsushi Kuroda; Ken J Ishii; Shigeyuki Magi; Mariko Okada; Hiroyuki Takao; Masahiro Gandou; Hirotaka Imai; Ryujiro Hara; Herbert Herzog; Akihiko Yoshimura; Hitoshi Okamura; Josef M Penninger; Arthur S Slutsky; Stefan Uhlig; Keiji Kuba; Yumiko Imai
Nature microbiology, Feb. 2019, [Reviewed] - Cyclic GMP-AMP Triggers Asthma in an IL-33-Dependent Manner That Is Blocked by Amlexanox, a TBK1 Inhibitor.
Koji Ozasa; Burcu Temizoz; Takato Kusakabe; Shingo Kobari; Masatoshi Momota; Cevayir Coban; Shuichi Ito; Kouji Kobiyama; Etsushi Kuroda; Ken J Ishii
Frontiers in immunology, 2019, [Reviewed] - 感染症とワクチン 細胞死が放出するDAMPsとそのワクチンへの応用
石井 健; 百田 匡寿; 日下部 峻斗; 林 智哉; 黒田 悦史
日本臨床免疫学会総会プログラム・抄録集, Nov. 2018 - Immunological association of inducible bronchus-associated lymphoid tissue organogenesis in Ag85B-rHPIV2 vaccine-induced anti-tuberculosis mucosal immune responses in mice.
Takahiro Nagatake; Hidehiko Suzuki; So-Ichiro Hirata; Naomi Matsumoto; Yasuko Wada; Sakiko Morimoto; Ayaka Nasu; Michiko Shimojou; Mitsuo Kawano; Kentaro Ogami; Yusuke Tsujimura; Etsushi Kuroda; Norifumi Iijima; Koji Hosomi; Ken J Ishii; Tetsuya Nosaka; Yasuhiro Yasutomi; Jun Kunisawa
International immunology, Sep. 2018, [Reviewed] - Combination and inducible adjuvants targeting nucleic acid sensors.
Burcu Temizoz; Etsushi Kuroda; Ken J Ishii
Current opinion in pharmacology, Aug. 2018, [Reviewed] - Unravelling how adjuvants work, and what their roles are in vaccination and allergy.
KURODA Etsushi
IMPACT, Jun. 2018, [Invited] - Carbonate Apatite Nanoparticles Act as Potent Vaccine Adjuvant Delivery Vehicles by Enhancing Cytokine Production Induced by Encapsulated Cytosine-Phosphate-Guanine Oligodeoxynucleotides.
Hideki Takahashi; Kazuki Misato; Taiki Aoshi; Yasuyuki Yamamoto; Yui Kubota; Xin Wu; Etsushi Kuroda; Ken J Ishii; Hirofumi Yamamoto; Yasuo Yoshioka
Frontiers in immunology, 2018, [Reviewed] - DAMP-Inducing Adjuvant and PAMP Adjuvants Parallelly Enhance Protective Type-2 and Type-1 Immune Responses to Influenza Split Vaccination.
Tomoya Hayashi; Masatoshi Momota; Etsushi Kuroda; Takato Kusakabe; Shingo Kobari; Kotaro Makisaka; Yoshitaka Ohno; Yusuke Suzuki; Fumika Nakagawa; Michelle S J Lee; Cevayir Coban; Risako Onodera; Taishi Higashi; Keiichi Motoyama; Ken J Ishii; Hidetoshi Arima
Frontiers in immunology, 2018, [Reviewed] - Isntillation of Particulate Suspensions to the Lungs
Kuroda E; Morimoto Y; Ishii KJ
Bio-protocol, Nov. 2017, [Reviewed], [Invited] - CD63-Mediated Antigen Delivery into Extracellular Vesicles via DNA Vaccination Results in Robust CD8+ T Cell Responses.
Tomohiro Kanuma; Takuya Yamamoto; Kouji Kobiyama; Eiko Moriishi; Yuji Masuta; Takato Kusakabe; Koji Ozasa; Etsushi Kuroda; Nao Jounai; Ken J Ishii
Journal of immunology (Baltimore, Md. : 1950), Jun. 2017, [Reviewed] - Plasmodium products persist in the bone marrow and promote chronic bone loss.
Michelle S J Lee; Kenta Maruyama; Yukiko Fujita; Aki Konishi; Patrick M Lelliott; Sawako Itagaki; Toshihiro Horii; Jing-Wen Lin; Shahid M Khan; Etsushi Kuroda; Shizuo Akira; Ken J Ishii; Cevayir Coban
Science immunology, Jun. 2017, [Reviewed] - アジュバントによる免疫活性化のメカニズム 免疫制御因子としてのデンジャーシグナル
黒田 悦史; 石井 健
The Journal of Toxicological Sciences, Jun. 2017 - Human scavenger receptor A1-mediated inflammatory response to silica particle exposure is size specific
Nobuo Nishijima; Toshiro Hirai; Kazuki Misato; Michihiko Aoyama; Etsushi Kuroda; Ken J. Ishii; Kazuma Higashisaka; Yasuo Yoshioka; Yasuo Tsutsumi
Frontiers in Immunology, Apr. 2017, [Reviewed] - Allergic Responses induced by the immunomodulatory effects of Nanomaterials upon Skin exposure
Yasuo Yoshioka; Etsushi Kuroda; Toshiro Hirai; Yasuo Tsutsumi; Ken J. Ishii
FRONTIERS IN IMMUNOLOGY, Feb. 2017, [Reviewed] - Particulates Induce Type-2 Immune Responses.
Kuroda E; Ishii KJ
Nihon eiseigaku zasshi. Japanese journal of hygiene, 2017, [Reviewed] - Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1 alpha Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation
Etsushi Kuroda; Koji Ozasa; Burcu Temizoz; Keiichi Ohata; Christine X. Koo; Tomohiro Kanuma; Takato Kusakabe; Shingo Kobari; Masanori Horie; Yasuo Morimoto; Saeko Nakajima; Kenji Kabashima; Steven F. Ziegler; Yoichiro Iwakura; Wataru Ise; Tomohiro Kurosaki; Takahiro Nagatake; Jun Kunisawa; Naoki Takemura; Satoshi Uematsu; Masayuki Hayashi; Taiki Aoshi; Kouji Kobiyama; Cevayir Coban; Ken J. Ishii
IMMUNITY, Dec. 2016, [Reviewed] - Circulating nano-particulate TLR9 agonist scouts out tumor microenvironment to release immunogenic dead tumor cells
Yuji Kitahata; Tomohiro Kanuma; Masayuki Hayashi; Nobuyoshi Kobayashi; Koji Ozasa; Takato Kusakabe; Burcu Temizoz; Etsushi Kuroda; Hiroki Yamaue; Cevayir Coban; Takuya Yamamoto; Kouji Kobiyama; Taiki Aoshi; Ken J. Ishii
ONCOTARGET, Aug. 2016, [Reviewed] - Evaluation of Pulmonary Toxicity of Zinc Oxide Nanoparticles Following Inhalation and Intratracheal Instillation
Yasuo Morimoto; Hiroto Izumi; Yukiko Yoshiura; Taisuke Tomonaga; Takako Oyabu; Toshihiko Myojo; Kazuaki Kawai; Kazuhiro Yatera; Manabu Shimada; Masaru Kubo; Kazuhiro Yamamoto; Shinichi Kitajima; Etsushi Kuroda; Kenji Kawaguchi; Takeshi Sasaki
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Aug. 2016, [Reviewed] - Vaccine adjuvants as potential cancer immunotherapeutics
Burcu Temizoz; Etsushi Kuroda; Ken J. Ishii
INTERNATIONAL IMMUNOLOGY, Jul. 2016, [Reviewed] - RNA is an Adjuvanticity Mediator for the Lipid-Based Mucosal Adjuvant, Endocine
Masayuki Hayashi; Taiki Aoshi; Koji Ozasa; Takato Kusakabe; Masatoshi Momota; Yasunari Haseda; Shingo Kobari; Etsushi Kuroda; Kouji Kobiyama; Cevayir Coban; Ken J. Ishii
SCIENTIFIC REPORTS, Jul. 2016, [Reviewed] - Intranasal hydroxypropyl-beta-cyclodextrin-adjuvanted influenza vaccine protects against sub-heterologous virus infection
Takato Kusakabe; Koji Ozasa; Shingo Kobari; Masatoshi Momota; Natsuko Kishishita; Kouji Kobiyama; Etsushi Kuroda; Ken J. Ishii
VACCINE, Jun. 2016, [Reviewed] - Comparison of pulmonary inflammatory responses following intratracheal instillation and inhalation of nanoparticles
Yasuo Morimoto; Hiroto Izumi; Yukiko Yoshiura; Taisuke Tomonaga; Byeong-Woo Lee; Takami Okada; Takako Oyabu; Toshihiko Myojo; Kazuaki Kawai; Kazuhiro Yatera; Manabu Shimada; Masaru Kubo; Kazuhiro Yamamoto; Shinichi Kitajima; Etsushi Kuroda; Masanori Horie; Kenji Kawaguchi; Takeshi Sasaki
NANOTOXICOLOGY, May 2016, [Reviewed] - Species-dependent role of type I IFNs and IL-12 in the CTL response induced by humanized CpG complexed with beta-glucan
Kouji Kobiyama; Burcu Temizoz; Tomohiro Kanuma; Koji Ozasa; Masatoshi Momota; Takuya Yamamoto; Taiki Aoshi; Etsushi Kuroda; Ken J. Ishii
EUROPEAN JOURNAL OF IMMUNOLOGY, May 2016, [Reviewed] - Metal Ion Release of Manufactured Metal Oxide Nanoparticles Is Involved in the Allergic Response to Inhaled Ovalbumin in Mice
Horie Masanori; Stowe Mayumi; Tabei Miki; Kuroda Etsushi
Occupational Diseases and Environmental Medicine, 2016, [Reviewed] - Optimization of physiological properties of hydroxyapatite as a vaccine adjuvant
Masayuki Hayashi; Taiki Aoshi; Yasumichi Kogai; Daisuke Nomi; Yasunari Haseda; Etsushi Kuroda; Kouji Kobiyama; Ken J. Ishii
VACCINE, Jan. 2016, [Reviewed] - Pulmonary toxicity of well-dispersed cerium oxide nanoparticles following intratracheal instillation and inhalation
Yasuo Morimoto; Hiroto Izumi; Yukiko Yoshiura; Taisuke Tomonaga; Takako Oyabu; Toshihiko Myojo; Kazuaki Kawai; Kazuhiro Yatera; Manabu Shimada; Masaru Kubo; Kazuhiro Yamamoto; Shinichi Kitajima; Etsushi Kuroda; Kenji Kawaguchi; Takeshi Sasaki
JOURNAL OF NANOPARTICLE RESEARCH, Nov. 2015, [Reviewed] - Pulmonary toxicity of well-dispersed titanium dioxide nanoparticles following intratracheal instillation
Yukiko Yoshiura; Hiroto Izumi; Takako Oyabu; Masayoshi Hashiba; Tatsunori Kambara; Yohei Mizuguchi; Byeong Woo Lee; Takami Okada; Taisuke Tomonaga; Toshihiko Myojo; Kazuhiro Yamamoto; Shinichi Kitajima; Masanori Horie; Etsushi Kuroda; Yasuo Morimoto
JOURNAL OF NANOPARTICLE RESEARCH, Jun. 2015, [Reviewed] - TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN
Burcu Temizoz; Etsushi Kuroda; Keiichi Ohata; Nao Jounai; Koji Ozasa; Kouji Kobiyama; Taiki Aoshi; Ken J. Ishii
EUROPEAN JOURNAL OF IMMUNOLOGY, Apr. 2015, [Reviewed] - Hydroxypropyl-beta-Cyclodextrin Spikes Local Inflammation That Induces Th2 Cell and T Follicular Helper Cell Responses to the Coadministered Antigen
Motoyasu Onishi; Koji Ozasa; Kouji Kobiyama; Keiichi Ohata; Mitsutaka Kitano; Keiichi Taniguchi; Tomoyuki Homma; Masanori Kobayashi; Akihiko Sato; Yuko Katakai; Yasuhiro Yasutomi; Edward Wijaya; Yoshinobu Igarashi; Noriyuki Nakatsu; Wataru Ise; Takeshi Inoue; Hiroshi Yamada; Alexis Vandenbon; Daron M. Standley; Tomohiro Kurosaki; Cevayir Coban; Taiki Aoshi; Etsushi Kuroda; Ken J. Ishii
JOURNAL OF IMMUNOLOGY, Mar. 2015, [Reviewed] - Pharyngeal aspiration of metal oxide nanoparticles showed potential of allergy aggravation effect to inhaled ovalbumin
Masanori Horie; Mayumi Stowe; Miki Tabei; Etsushi Kuroda
INHALATION TOXICOLOGY, Feb. 2015, [Reviewed] - Development of Nonaggregating Poly-A Tailed Immunostimulatory A/D Type CpG Oligodeoxynucleotides Applicable for Clinical Use
Taiki Aoshi; Yasunari Haseda; Kouji Kobiyama; Hirotaka Narita; Hideaki Sato; Hirokazu Nankai; Shinichi Mochizuki; Kazuo Sakurai; Yuko Katakai; Yasuhiro Yasutomi; Etsushi Kuroda; Cevayir Coban; Ken J. Ishii
JOURNAL OF IMMUNOLOGY RESEARCH, 2015, [Reviewed] - Expression of cytokine-induced neutrophil chemoattractant in rat lungs following an intratracheal instillation of micron-sized nickel oxide nanoparticle agglomerates
Yasuo Morimoto; Masami Hirohashi; Akira Ogami; Takako Oyabu; Toshihiko Myojo; Masayoshi Hashiba; Yohei Mizuguchi; Tatsunori Kambara; Byeong Woo Lee; Etsushi Kuroda; Isamu Tanaka
TOXICOLOGY AND INDUSTRIAL HEALTH, Oct. 2014, [Reviewed] - An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells
Shinsuke Yasukawa; Yoshiyuki Miyazaki; Chika Yoshii; Mako Nakaya; Naoko Ozaki; Shuji Toda; Etsushi Kuroda; Ken-ichi Ishibashi; Tomoharu Yasuda; Yohei Natsuaki; Fumika Mi-ichi; Ei'ichi Iizasa; Takeshi Nakahara; Masanori Yamazaki; Kenji Kabashima; Yoichiro Iwakura; Toshiyuki Takai; Takashi Saito; Tomohiro Kurosaki; Bernard Malissen; Naohito Ohno; Masutaka Furue; Hiroki Yoshida; Hiromitsu Hara
NATURE COMMUNICATIONS, May 2014, [Reviewed] - Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist
Kouji Kobiyama; Taiki Aoshi; Hirotaka Narita; Etsushi Kuroda; Masayuki Hayashi; Kohhei Tetsutani; Shohei Koyama; Shinichi Mochizuki; Kazuo Sakurai; Yuko Katakai; Yasuhiro Yasutomi; Shinobu Saijo; Yoichiro Iwakura; Shizuo Akira; Cevayir Coban; Ken J. Ishii
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Feb. 2014, [Reviewed] - MafB promotes atherosclerosis by inhibiting foam-cell apoptosis
Michito Hamada; Megumi Nakamura; Mai Thi Nhu Tran; Takashi Moriguchi; Cynthia Hong; Takayuki Ohsumi; Tra Thi Huong Dinh; Manabu Kusakabe; Motochika Hattori; Tokio Katsumata; Satoko Arai; Katsuhiko Nakashima; Takashi Kudo; Etsushi Kuroda; Chien-Hui Wu; Pei-Han Kao; Masaharu Sakai; Hitoshi Shimano; Toru Miyazaki; Peter Tontonoz; Satoru Takahashi
NATURE COMMUNICATIONS, Jan. 2014, [Reviewed] - Significance of Persistent Inflammation in Respiratory Disorders Induced by Nanoparticles
Yasuo Morimoto; Hiroto Izumi; Etsushi Kuroda
JOURNAL OF IMMUNOLOGY RESEARCH, 2014, [Reviewed] - Pulmonary toxicity of printer toner following inhalation and intratracheal instillation
Yasuo Morimoto; Takako Oyabu; Masanori Horie; Tatsunori Kambara; Hiroto Izumi; Etsushi Kuroda; Otto Creutzenberg; Bernd Bellmann; Gerhard Pohlmann; Sven Schuchardt; Tanja Hansen; Heinrich Ernst
INHALATION TOXICOLOGY, Oct. 2013, [Reviewed] - Prostaglandin E-2 is critical for the development of niacin-deficiency-induced photosensitivity via ROS production
Kazunari Sugita; Atsuko Ikenouchi-Sugita; Yasuko Nakayama; Haruna Yoshioka; Takashi Nomura; Jun-ichi Sakabe; Kyoko Nakahigashi; Etsushi Kuroda; Satoshi Uematsu; Jun Nakamura; Shizuo Akira; Motonobu Nakamura; Shuh Narumiya; Yoshiki Miyachi; Yoshiki Tokura; Kenji Kabashima
SCIENTIFIC REPORTS, Oct. 2013, [Reviewed] - D1-like dopamine receptors antagonist inhibits cutaneous immune reactions mediated by Th2 and mast cells
Tomoko Mori; Kenji Kabashima; Shoko Fukamachi; Etsushi Kuroda; Jun-ichi Sakabe; Miwa Kobayashi; Saeko Nakajima; Kazuhisa Nakano; Yoshiya Tanaka; Sho Matsushita; Motonobu Nakamura; Yoshiki Tokura
JOURNAL OF DERMATOLOGICAL SCIENCE, Jul. 2013, [Reviewed] - Dose-dependent pulmonary response of well-dispersed titanium dioxide nanoparticles following intratracheal instillation
Takako Oyabu; Yasuo Morimoto; Masami Hirohashi; Masanori Horie; Tatsunori Kambara; Byeong Woo Lee; Masayoshi Hashiba; Yohei Mizuguchi; Toshihiko Myojo; Etsushi Kuroda
JOURNAL OF NANOPARTICLE RESEARCH, Apr. 2013, [Reviewed] - Particulate Adjuvant and Innate Immunity: Past Achievements, Present Findings, and Future Prospects
Etsushi Kuroda; Cevayir Coban; Ken J. Ishii
INTERNATIONAL REVIEWS OF IMMUNOLOGY, Apr. 2013, [Reviewed] - The Chemotherapeutic Agent DMXAA as a Unique IRF3-Dependent Type-2 Vaccine Adjuvant
Choon Kit Tang; Taiki Aoshi; Nao Jounai; Junichi Ito; Keiichi Ohata; Kouji Kobiyama; Benoit H. Dessailly; Etsushi Kuroda; Shizuo Akira; Kenji Mizuguchi; Cevayir Coban; Ken J. Ishii
PLOS ONE, Mar. 2013, [Reviewed] - Generation and characterization of murine alternatively activated macrophages.
Weisser SB, McLarren KW; Kuroda E; Sly LM
Methods in molecular biology (Clifton, N.J.), 2013, [Reviewed] - Pulmonary toxicity of well-dispersed single-wall carbon nanotubes after inhalation
Yasuo Morimoto; Masami Hirohashi; Norihiro Kobayashi; Akira Ogami; Masanori Horie; Takako Oyabu; Toshihiko Myojo; Masayoshi Hashiba; Yohei Mizuguchi; Tatsunori Kambara; Byeong Woo Lee; Etsushi Kuroda; Manabu Shimada; Wei-Ning Wang; Kohei Mizuno; Kazuhiro Yamamoto; Katsuhide Fujita; Junko Nakanishi; Isamu Tanaka
NANOTOXICOLOGY, Nov. 2012, [Reviewed] - Pulmonary toxicity of well-dispersed multi-wall carbon nanotubes following inhalation and intratracheal instillation
Yasuo Morimoto; Masami Hirohashi; Akira Ogami; Takako Oyabu; Toshihiko Myojo; Motoi Todoroki; Makoto Yamamoto; Masayoshi Hashiba; Yohei Mizuguchi; Byeong Woo Lee; Etsushi Kuroda; Manabu Shimada; Wei-Ning Wang; Kazuhiro Yamamoto; Katsuhide Fujita; Shigehisa Endoh; Kunio Uchida; Norihiro Kobayashi; Kohei Mizuno; Masaharu Inada; Hiroaki Tao; Tetsuya Nakazato; Junko Nakanishi; Isamu Tanaka
NANOTOXICOLOGY, Sep. 2012, [Reviewed] - Pulmonary inflammation of well-dispersed multi-wall carbon nanotubes following intratracheal instillation: Toxicity by fiber of 1-5 μm in length
Masanori Horie; Mayumi Stowe; Tatsunori Kambara; Byeong Woo Lee; Shigehisa Endoh; Junko Maru; Takako Oyabu; Toshihiko Myojo; Akira Ogami; Kunio Uchida; Kazuhiro Yamamoto; Norihiro Kobayashi; Etsushi Kuroda; Tetsuya Nakazato; Yasuo Morimoto
Materials, 2012, [Reviewed] - Pulmonary Toxicity of Well-dispersed Single-wall Carbon Nanotubes Following Intratracheal Instillation
Yasuo Morimoto; Masami Hirohashi; Masanori Horie; Akira Ogami; Takako Oyabu; Toshihiko Myojo; Masayoshi Hashiba; Yohei Mizuguchi; Tatsunori Kambara; Byeong Woo Lee; Etsushi Kuroda; Kazuhiro Yamamoto; Norihiro Kobayashi; Shigehisa Endoh; Kunio Uchida; Tetsuya Nakazato; Katsuhide Fujita; Junko Nakanishi; Isamu Tanaka
JOURNAL OF NANO RESEARCH, 2012, [Reviewed] - Synergism of Staphylococcus aureus Colonization and Allergic Reaction in the Nasal Cavity in Mice
Nobusuke Hohchi; Koichi Hashida; Jun-ichi Ohkubo; Tetsuro Wakasugi; Takanori Mori; Khac-Hung Nguyen; Etsushi Kuroda; Takako Ikeno; Hatsumi Taniguchi; Hideaki Suzuki
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 2012, [Reviewed] - Possibility of exacerbation of allergy by lunar regolith
Masanori Horie; Tatsunori Kambara; Etsushi Kuroda; Takeo Miki; Yoshiyuki Honma; Shigeru Aoki; Yasuo Morimoto
Journal of UOEH, 2012, [Reviewed] - Pulmonary Toxicity Following an Intratracheal Instillation of Nickel Oxide Nanoparticle Agglomerates
Yasuo Morimoto; Masami Hirohashi; Akira Ogami; Takako Oyabu; Toshihiko Myojo; Masayoshi Hashiba; Yohei Mizuguchi; Tatsunori Kambara; Byeong Woo Lee; Etsushi Kuroda; Isamu Tanaka
JOURNAL OF OCCUPATIONAL HEALTH, Jul. 2011, [Reviewed] - Investigation of Gene Expression of MMP-2 and TIMP-2 mRNA in Rat Lung in Inhaled Nickel Oxide and Titanium Dioxide Nanoparticles
Yasuo Morimoto; Takako Oyabu; Akira Ogami; Toshihiko Myojo; Etsushi Kuroda; Masami Hirohashi; Manabu Shimada; Wuled Lenggoro; Kikuo Okuyama; Isamu Tanaka
INDUSTRIAL HEALTH, May 2011, [Reviewed] - Topical Cholecystokinin Depresses Itch-Associated Scratching Behavior in Mice
Shoko Fukamachi; Tomoko Mori; Jun-Ichi Sakabe; Noriko Shiraishi; Etsushi Kuroda; Miwa Kobayashi; Toshinori Bito; Kenji Kabashima; Motonobu Nakamura; Yoshiki Tokura
JOURNAL OF INVESTIGATIVE DERMATOLOGY, Apr. 2011, [Reviewed] - Silica Crystals and Aluminum Salts Regulate the Production of Prostaglandin in Macrophages via NALP3 Inflammasome-Independent Mechanisms
Etsushi Kuroda; Ken J. Ishii; Satoshi Uematsu; Keiichi Ohata; Cevayir Coban; Shizuo Akira; Kosuke Aritake; Yoshihiro Urade; Yasuo Morimoto
IMMUNITY, Apr. 2011, [Reviewed] - Role of SHIP in cancer
Melisa J. Hamilton; Victor W. Ho; Etsushi Kuroda; Jens Ruschmann; Frann Antignano; Vivian Lam; Gerald Krystal
EXPERIMENTAL HEMATOLOGY, Jan. 2011, [Reviewed] - SHIP Represses Th2 Skewing by Inhibiting IL-4 Production from Basophils
Etsushi Kuroda; Frann Antignano; Victor W. Ho; Michael R. Hughes; Jens Ruschmann; Vivian Lam; Toshiaki Kawakami; William G. Kerr; Kelly M. McNagny; Laura M. Sly; Gerald Krystal
JOURNAL OF IMMUNOLOGY, Jan. 2011, [Reviewed] - Tyrosine phosphorylation of SHIP promotes its proteasomal degradation
Jens Ruschmann; Victor Ho; Frann Antignano; Etsushi Kuroda; Vivian Lam; Mariko Ibaraki; Kim Snyder; Connie Kim; Richard A. Flavell; Toshiaki Kawakami; Laura Sly; Ali G. Turhan; Gerald Krystal
EXPERIMENTAL HEMATOLOGY, May 2010, [Reviewed] - SHIP Represses the Generation of IL-3-Induced M2 Macrophages by Inhibiting IL-4 Production from Basophils
Etsushi Kuroda; Victor Ho; Jens Ruschmann; Frann Antignano; Melisa Hamilton; Michael J. Rauh; Andrey Antov; Richard A. Flavell; Laura M. Sly; Gerald Krystal
JOURNAL OF IMMUNOLOGY, Sep. 2009, [Reviewed] - The NF-kappa B RelA Subunit Confers Resistance to Leishmania major by Inducing Nitric Oxide Synthase 2 and Fas Expression but Not Th1 Differentiation
Setsuko Mise-Omata; Etsushi Kuroda; Tsutomu Sugiura; Uki Yamashita; Yuichi Obata; Takahiro S. Doi
JOURNAL OF IMMUNOLOGY, Apr. 2009, [Reviewed] - SHIP prevents lipopolysaccharide from triggering an antiviral response in mice
Laura M. Sly; Melisa J. Hamilton; Etsushi Kuroda; Victor W. Ho; Frann L. Antignano; Stephanie L. Omeis; Christina J. van Netten-Thomas; Dana Wong; Hayley K. Brugger; Olusegun Williams; Morris E. Feldman; Benjamin T. Houseman; Dorothea Fiedler; Kevan M. Shokat; Gerald Krystal
BLOOD, Mar. 2009, [Reviewed] - Cutaneous hypersensitivities to hapten are controlled by IFN-gamma-upregulated keratinocyte Th1 chemokines and IFN-gamma-downregulated Langerhans cell Th2 chemokines
Tomoko Mori; Kenji Kabashima; Ryutaro Yoshiki; Kazunari Sugita; Noriko Shiraishi; Ayako Onoue; Etsushi Kuroda; Miwa Kobayashi; Uki Yamashita; Yoshiki Tokura
JOURNAL OF INVESTIGATIVE DERMATOLOGY, Jul. 2008, [Reviewed] - Induction of prostaglandin E-2 synthesis and microsomal prostaglandin E synthase-1 expression in murine microglia by glioma-derived soluble factors
Yoshiteru Nakano; Etsushi Kuroda; Tomohiro Kito; Satoshi Uematsu; SHizuo Akira; Akira Yokota; Shigeru Nishizawa; Uki Yamashita
JOURNAL OF NEUROSURGERY, Feb. 2008, [Reviewed] - A proximal kappa B site in the IL-23 p19 promoter is responsible for RelA- and c-rel-dependent transcription
Setsuko Mise-Omata; Etsushi Kuroda; Junko Niikura; Uki Yamashita; Yuichi Obata; Takahiro S. Doi
JOURNAL OF IMMUNOLOGY, Nov. 2007, [Reviewed] - Role of cytokine in implantation and maintenance of pregnancy
Hiroyuki Horita; Etsushi Kuroda; Tooru Hachisuga
Journal of UOEH, Sep. 2007, [Reviewed] - IL-3 is an important differentiation factor for the development of prostaglandin E-2-producing macrophages between C57BL/6 and BALB/c mice
Etsushi Kuroda; Junko Noguchi; Takahiro Doi; Satoshi Uematsu; Sizuo Akira; Uki Yamashita
EUROPEAN JOURNAL OF IMMUNOLOGY, Aug. 2007, [Reviewed] - Induction of prostaglandin E-2 production by leukemia inhibitory factor promotes migration of first trimester extravillous trophoblast cell line, HTR-8/SVneo
Hiroyuki Horita; Etsushi Kuroda; Tooru Hachisuga; Masamichi Kashimura; Uki Yamashita
HUMAN REPRODUCTION, Jul. 2007, [Reviewed] - Differential expression of EC-SOD, Mn-SOD and CuZn-SOD in rat lung exposed to crystalline silica
Heungnam Kim; Yasuo Morimoto; Akira Ogami; Hiroko Nagatomo; Masami Hirohashi; Takako Oyabu; Yukiko Kawanami; Etsushi Kuroda; Toshiaki Higashi; Isamu Tanaka
JOURNAL OF OCCUPATIONAL HEALTH, May 2007, [Reviewed] - MafB is essential for renal development and F4/80 expression in macrophages
Takashi Moriguchi; Michito Hamada; Naoki Morito; Tsumoru Terunuma; Kazuteru Hasegawa; Chuan Zhang; Tomomasa Yokomizo; Ritsuko Esaki; Etsushi Kuroda; Keigyou Yoh; Takashi Kudo; Michio Nagata; David R. Greaves; James Douglas Engel; Masayuki Yamamoto; Satoru Takahashi
MOLECULAR AND CELLULAR BIOLOGY, Aug. 2006, [Reviewed] - Induction of macrophagic prostaglandin E-2 synthesis by glioma cells
Y Nakano; E Kuroda; T Kito; A Yokota; U Yamashita
JOURNAL OF NEUROSURGERY, Apr. 2006, [Reviewed] - Strain difference of murine bone marrow-derived mast cell functions
J Noguchi; E Kuroda; U Yamashita
JOURNAL OF LEUKOCYTE BIOLOGY, Sep. 2005, [Reviewed] - Effect of endocrine disrupters on macrophage functions in vitro
Uki Yamashita; Tsutomu Sugiura; Yasuhiro Yoshida; Etsushi Kuroda
Journal of UOEH, Mar. 2005, [Reviewed] - Effects of interferon-beta on the cytokine production of astrocytes
K Okada; E Kuroda; Y Yoshida; U Yamashita; A Suzumura; S Tsuji
JOURNAL OF NEUROIMMUNOLOGY, Feb. 2005, [Reviewed] - Dysfunction of macrophages in metallothionein-knock out mice
Tsutomu Sugiura; Etsushi Kuroda; Uki Yamashita
Journal of UOEH, Jun. 2004, [Reviewed] - Assay system for the effect of prostaglandin E(2) in the determination of polarized cytokine production.
Kuroda E; Yamashita U
Methods in molecular biology (Clifton, N.J.), 2004, [Reviewed] - Effect of Endocrine Disrupters on Immune Responses In Vivo
Uki Yamashita; Etsushi Kuroda; Yasuhiro Yoshida; Tsutomu Sugiura
Journal of UOEH, Dec. 2003, [Reviewed] - Effect of endocrine disrupters on thymocytes in vitro
Uki Yamashita; Tsutomu Sugiura; Yasuhiro Yoshida; Etsushi Kuroda
Journal of UOEH, Jun. 2003, [Reviewed] - Cytotoxicity in glioma cells due to interleukin-12 and interleukin-18-stimulated macrophages mediated by interferon-gamma-regulated nitric oxide
T Kito; E Kuroda; A Yokota; U Yamashita
JOURNAL OF NEUROSURGERY, Feb. 2003, [Reviewed] - Mechanisms of enhanced macrophage-mediated prostaglandin E-2 production and its suppressive role in Th1 activation in Th2-dominant BALB/c mice
E Kuroda; U Yamashita
JOURNAL OF IMMUNOLOGY, Jan. 2003, [Reviewed] - The long-term high-frequency repetitive transcranial magnetic stimulation does not induce mRNA expression of inflammatory mediators in the rat central nervous system
K Okada; K Matsunaga; T Yuhi; E Kuroda; U Yamashita; S Tsuji
BRAIN RESEARCH, Dec. 2002, [Reviewed] - Regulation of immune responses by prostaglandin
Etsushi Kuroda; Uki Yamashita
Journal of UOEH, Sep. 2002, [Reviewed] - Enhancement of macrophage cytotoxicity against murine gliomas by interferon beta: increase in nitric oxide production in response to glioma-derived soluble factors
T Kito; E Kuroda; A Yokota; U Yamashita
JOURNAL OF NEUROSURGERY, Sep. 2002, [Reviewed] - Reduced expression of STAT4 and IFN-gamma in macrophages from BALB/c mice
E Kuroda; T Kito; U Yamashita
JOURNAL OF IMMUNOLOGY, Jun. 2002, [Reviewed] - Prostaglandin E-2 down-regulates viable Bacille Calmette-Guerin-induced macrophage cytotoxicity against murine bladder cancer cell MBT-2 in vitro
H Yamada; E Kuroda; S Matsumoto; T Matsumoto; T Yamada; U Yamashita
CLINICAL AND EXPERIMENTAL IMMUNOLOGY, Apr. 2002, [Reviewed] - Effect of endocrine disrupters on immune responses In Vitro
Uki Yamashita; Tsutomu Sugiura; Etsushi Kuroda
Journal of UOEH, Mar. 2002, [Reviewed] - Regulation of macrophage-derived chemokine (MDC, CCL22) production
U Yamashita; E Kuroda
CRITICAL REVIEWS IN IMMUNOLOGY, 2002, [Reviewed] - Phenytoin promotes Th2 type immune response in mice
K Okada; T Sugiura; E Kuroda; S Tsuji; U Yamashita
CLINICAL AND EXPERIMENTAL IMMUNOLOGY, Jun. 2001, [Reviewed] - Cytotoxic effect of an anti-liver monoclonal autoantibody obtained after neonatal thymectomy in mice
Y Yoshida; M Myozaki; E Kuroda; U Yamashita
JOURNAL OF AUTOIMMUNITY, Jun. 2001, [Reviewed] - Role of TGF-β in the retinoic acid-induced inhibition of proliferation and melanin synthesis in chick retinal pigment epithelial cells in vitro
Hiroko Kishi; Etsushi Kuroda; Hiromu K. Mishima; Uki Yamashita
Cell Biology International, 2001, [Reviewed] - Macrophage-colony stimulating factor inhibits the growth of human ovarian cancer cells in vitro
Y Kawakami; N Nagai; K Ohama; K Zeki; Y Yoshida; E Kuroda; U Yamashita
EUROPEAN JOURNAL OF CANCER, Oct. 2000, [Reviewed] - Effect of mite antigens on antigen presenting cells/macrophages in mice
J. Noguchi; E. Kuroda; K. Ono; U. Yamashita
Journal of UOEH, Sep. 2000, [Reviewed] - Reduced interleukin-1 beta reactivity in the immune system and the central nervous system of inbred polydipsic mice
K Okada; Y Yoshida; E Kuroda; H Yamashita; U Yamashita
CONTROL MECHANISMS OF STRESS AND EMOTION: NEUROENDOCRINE-BASED STUDIES, 1999, [Reviewed] - Immunomodulating activity of seaweed extract on human lymphocytes in vitro
BE Shan; Y Yoshida; E Kuroda; U Yamashita
INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, Jan. 1999, [Reviewed] - Dysfunction of immune system and induction of autoantibodies to liver antigens by neonatal thymectomy in mice
Mitsuru Myozaki; Mei Qi Wang; Yasuhiro Yoshida; Jia Nuo Liu; Etsushi Kuroda; Uki Yamashita
Hiroshima Journal of Medical Sciences, Sep. 1996, [Reviewed]
MISC
- Applying imaging flow cytometry for the characterization and quantification of NETosis and cell death in vitro and in vivo
Patrick M. Lelliott; Masatoshi Momota; Michelle S. J. Lee; Etsushi Kuroda; Norifumi Iijima; Ken J. Ishii; Cevayir Coban
CELL DEATH DISCOVERY, Jan. 2019 - 血管炎とアレルギー疾患―内因性・外因性アジュバントの関わり―I.微細粒子によるIL‐1誘導とアレルギー性炎症
黒田悦史; 黒田悦史; 黒田悦史; 小張真吾; 日下部峻斗; 日下部峻斗; 石井健; 石井健
アレルギー・免疫, 15 May 2018 - 微細粒子吸入によるアレルギー性炎症発症機序の解析~肺胞マクロファージの細胞死と三次リンパ節(iBALT)形成~
黒田悦史; 黒田悦史; 森本泰夫; 石井健; 石井健
分子呼吸器病, 01 Mar. 2018 - The role of Tfh cells, DCs and iBALT formations in inhaled fine particle-induced allergic inflammation in the lungs
Etsushi Kuroda; Ken J. Ishii
CYTOKINE, Dec. 2017 - 免疫学の新展開と呼吸器疾患 基礎医学とのダイアローグ アジュバントと抗原を含有するナノ粒子を用いる次世代ワクチン
日下部峻斗; 黒田悦史; 石井健
Lung Perspectives, 01 Dec. 2017 - 自然免疫に関する新規知見と発展 微細粒子吸入によるアレルギー性炎症におけるIL‐1と異所性リンパ組織の役割
黒田悦史; 黒田悦史; 小張真吾; 小張真吾; 小張真吾; 日下部峻斗; 日下部峻斗; 石井健; 石井健
月刊臨床免疫・アレルギー科, 25 Oct. 2017 - 職業・環境アレルギーの最前線 I.微細粒子吸入によるアレルギー性炎症発症のメカニズム
黒田悦史; 黒田悦史; 小張真吾; 小張真吾; 日下部峻斗; 日下部峻斗; 石井健; 石井健
アレルギー・免疫, 15 Oct. 2017 - がん免疫療法―What’s now and what’s next?―第4章 次世代がん免疫療法へのチャレンジ 2.アジュバントがつなぐ自然免疫と獲得免疫
神沼智裕; 神沼智裕; 黒田悦史; 黒田悦史; 黒田悦史; 石井健; 石井健; 石井健
遺伝子医学MOOK, 31 Jul. 2017 - 【がん免疫療法-What's now and what's next?-】 (第4章)次世代がん免疫療法へのチャレンジ アジュバントがつなぐ自然免疫と獲得免疫
神沼 智裕; 黒田 悦史; 石井 健
遺伝子医学MOOK, Jul. 2017 - がん免疫療法 腫瘍免疫学の最新知見から治療法のアップデートまで 第I部 腫瘍免疫応答の基本とその制御メカニズム 第3章 がん免疫応答の制御方法 1.がん免疫アジュバント
黒田悦史; 黒田悦史; 黒田悦史; TEMIZOZ Burcu; TEMIZOZ Burcu; 石井健; 石井健; 石井健
実験医学, 01 Aug. 2016 - Novel adjuvants
Burcu Temizoz; Etsushi Kuroda; Kouji Kobiyama; Taiki Aoshi; Ken J. Ishii
Immunotherapy of Cancer: An Innovative Treatment Comes of Age, 22 Feb. 2016 - Particulates induce macrophages to produce lipid mediators via the Syk activation
Etsushi Kuroda; Keiichi Ohata; Cevayir Coban; Ken Ishii
JOURNAL OF IMMUNOLOGY, May 2012 - Particulates control immune responses via signaling by lipid mediator.
Etsushi Kuroda
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012 - Establishment and PGE2 requirement of a new mouse model for pellagra
Kazunari Sugita; Kenji Kabashima; Jun-Ichi Sakabe; Etsushi Kuroda; Motonobu Nakamura; Yoshiki Tokura
JOURNAL OF INVESTIGATIVE DERMATOLOGY, Sep. 2011 - The mandatory role of P13-kinase pathway in IL-4 and IL-13 production by basophils stimulated with IgE and antigen
Jun-ichi Sakabe; Etsushi Kuroda; Motonobu Nakamura; Yoshiki Tokura
JOURNAL OF INVESTIGATIVE DERMATOLOGY, Sep. 2010 - TOPICAL CHOLECYTOKININ DEPRESSES ITCH-ASSOCIATED SCRATCHING BEHAVIOR IN MICE
Shoko Fukamachi; Tomoko Mori; Jun-ichi Sakabe; Noriko Shiraishi; Etsushi Kuroda; Hidetada Matsuoka; Toshinori Bito; Kenji Kabashima; Motonobu Nakamura; Yoshiki Tokura
ACTA DERMATO-VENEREOLOGICA, 2009 - M1マクロファージ,M2マクロファージの分化とSHIP
黒田悦史; SLY Laura M; HO Victor; RAUH Mochael J; KRYSTAL Gerald; 山下優毅
月刊臨床免疫・アレルギー科, 25 Oct. 2008 - Cutaneous hypersensitivities to hapten are controlled by IFN-gamma-upregulated keratinocyte Th1 chemokines and IFN-gamma-downregulated langerhans cell Th2 chemokines
T. Mori; K. Kabashima; R. Yoshiki; K. Sugita; N. Shiraishi; A. Onoue; E. Kuroda; M. Kobayashi; U. Yamashita; Y. Tokura
JOURNAL OF INVESTIGATIVE DERMATOLOGY, Apr. 2008 - 38.Trimellitic anhydride(TMA)に対する接触性過敏反応の誘導におけるプロスタグランジンの役割(第25回産業医科大学学会総会 学術講演会記録)
山下 優毅; 黒田 悦史
産業医科大学雑誌, 01 Mar. 2008 - 13.化学物質による接触過敏反応の発症機構の解明 : プロスタグランジンE_2合成酵素欠損マウスを用いた新しいアプローチ(第24回産業医科大学学会総会 学術講演会記録)
黒田 悦史; 山下 優毅
産業医科大学雑誌, 01 Mar. 2007 - Analysis of genes controlling strain differences in murine macrophage functions
Etsushi Kuroda; Uki Yamashita
JOURNAL OF IMMUNOLOGY, Apr. 2006 - 7. 癌細胞-マクロファージ相互作用によるマクロファージからのPGE_2産生増強と抗腫瘍免疫の抑制(第22回産業医科大学学会総会 学術講演会記録)
中野 良昭; 黒田 悦史; 鬼頭 知宏; 横田 晃; 山下 優毅
産業医科大学雑誌, 01 Mar. 2005 - Enhanced PGE2 and PGD2 production by macrophages in Th2-dominant BALB/c mice are committed at the early stage of development from bone marrow precursors
E Kuroda; U Yamashita
FASEB JOURNAL, Mar. 2005 - Mechanisms of enhanced macrophage-mediated prostaglandin E-2 production and its suppressive role in Th1 activation in Th2-dominant BALB/c mice
E Kuroda; U Yamashita
JOURNAL OF INVESTIGATIVE DERMATOLOGY, Nov. 2003 - Regulation of immune responses by prostaglandin
Etsushi Kuroda; Uki Yamashita
Journal of UOEH, 01 Sep. 2002 - Reduced expression of STAT4 and IFN-gamma in macrophages from BALB/c mice
E Kuroda; T Kito; U Yamashita
JOURNAL OF IMMUNOLOGY, Jun. 2002 - Suppression of macrophage interleukin-12 and tumour necrosis factor-alpha production in mice infected with Toxocara canis
E Kuroda; Y Yoshida; BE Shan; U Yamashita
PARASITE IMMUNOLOGY, Jun. 2001 - Prostaglandin E-2 up-regulates macrophage-derived chemokine production but suppresses IFN-Inducible protein-10 production by APC
E Kuroda; T Sugiura; K Okada; K Zeki; U Yamashita
JOURNAL OF IMMUNOLOGY, Feb. 2001 - Sensitivity difference to the suppressive effect of prostaglandin E2 among mouse strains: A possible mechanism to polarize Th2 type response in BALB/c mice
E Kuroda; T Sugiura; K Zeki; Y Yoshida; U Yamashita
JOURNAL OF IMMUNOLOGY, Mar. 2000 - バセドウ病モデルマウスのTSH receptorにより惹起される免疫応答におけるinterleukin-5の関与
是木 一也; 黒田 悦史; 吉田 安宏; 森本 勲夫; 下条 直樹; 河野 陽一; 江藤 澄哉; 山下 優毅
日本内分泌学会雑誌, Sep. 1999
Affiliated academic society
Research Themes
- Assessing the risk of lung cancer development and malignant transformation caused by PM2.5, as well as elucidating its mechanism of action
Grant-in-Aid for Scientific Research (B)
Niigata University
01 Apr. 2024 - 31 Mar. 2027 - Analysis of pathogenic alveolar macrophages which release IL-1alpha in response to fine particles.
Grant-in-Aid for Scientific Research (B)
Hyogo Medical University
01 Apr. 2023 - 31 Mar. 2026 - 環境化学物質による眼免疫活性化を介した新規アレルギー性炎症発症機構の解析
Grant-in-Aid for Scientific Research (B)
Hyogo College of Medicine
01 Apr. 2020 - 31 Mar. 2023 - 免疫制御可能な機能性ペプチドの網羅的創製と創薬展開
Grant-in-Aid for Scientific Research (B)
Osaka University
01 Apr. 2017 - 31 Mar. 2020 - Analysis of allergic inflammation triggered by eyes.
Challenging Research (Exploratory)
National Institutes of Biomedical Innovation, Health and Nutrition
30 Jun. 2017 - 31 Mar. 2019 - The impact of alveolar macrophage death by fine particle on allergic inflammation
Grant-in-Aid for Scientific Research (B)
01 Apr. 2016 - 31 Mar. 2019 - Development of novel pertussis vaccine
Grant-in-Aid for Challenging Exploratory Research
Osaka University
01 Apr. 2015 - 31 Mar. 2017 - Novel anti-sepsis strategy targeting the endothelial cell-specific receptor Robo4
Grant-in-Aid for Scientific Research (B)
Osaka University
01 Apr. 2014 - 31 Mar. 2017 - Experimental study on prevention and therapy of autoimmune diseases using lowly pathogenic parasitic helminths
Grant-in-Aid for Scientific Research (C)
University of Occupational and Environmental Health, Japan
01 Apr. 2013 - 31 Mar. 2016 - Analysis of particulate-induced allergic responses
Grant-in-Aid for Scientific Research (C)
Osaka University
01 Apr. 2012 - 31 Mar. 2015 - Development of estimamation system of harmful effect under the space environment
Grant-in-Aid for Scientific Research (C)
University of Occupational and Environmental Health, Japan
2011 - 2013 - The influence on bone marrow cells of the indoor environment chemicals: Analysis of dendritic cell differentiation and the Treg induction
Grant-in-Aid for Scientific Research (C)
University of Occupational and Environmental Health, Japan
2011 - 2013 - Study on schistosome's suppressive mechanisms against Th17-type inflammation
Grant-in-Aid for Scientific Research (C)
University of Occupational and Environmental Health, Japan
2010 - 2012 - Innovation of a novel treatment for chronic allergic dermatitis using PI3-kinase inhibitors
Grant-in-Aid for Young Scientists (B)
University of Occupational and Environmental Health, Japan
2010 - 2011 - PI3キナーゼ阻害剤を用いた慢性アレルギー性皮膚炎発症の制御
Grant-in-Aid for Research Activity start-up
University of Occupational and Environmental Health, Japan
2009 - 2010 - Mechanism of immuno suppression by glioma-Role of microglia and prostaglandin.
Grant-in-Aid for Scientific Research (C)
University of Occupational and Environmental Health, Japan
2006 - 2007 - プロスタグランジンE2合成酵素欠損マウスを用いた接触過敏反応の発症機序の解析
Grant-in-Aid for Young Scientists (B)
University of Occupational and Environmental Health, Japan
2006 - 2007 - Mechanism of enhanced production of prostaglandins in BALB/c macrophages
Grant-in-Aid for Scientific Research (C)
University of Occupational and Environmental Health(UOEH)
2003 - 2004 - Study on the function of Macrophages
