Last Updated :2024/09/11
Researcher Information
Career
Research activity information
Paper
- Beclin1 is essential for the pancreas development.
Sally Mehanna; Satoko Arakawa; Mai Imasaka; Wenting Chen; Yuto Nakanishi; Hiroshi Nishiura; Shigeomi Shimizu; Masaki Ohmuraya
Developmental biology, Dec. 2023 - Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis.
Yuichi Tsuchiya; Takao Seki; Kenta Kobayashi; Sachiko Komazawa-Sakon; Shigeyuki Shichino; Takashi Nishina; Kyoko Fukuhara; Kenichi Ikejima; Hidenari Nagai; Yoshinori Igarashi; Satoshi Ueha; Akira Oikawa; Shinya Tsurusaki; Soh Yamazaki; Chiharu Nishiyama; Tetuo Mikami; Hideo Yagita; Ko Okumura; Taketomo Kido; Atsushi Miyajima; Kouji Matsushima; Mai Imasaka; Kimi Araki; Toru Imamura; Masaki Ohmuraya; Minoru Tanaka; Hiroyasu Nakano
Nature communications, Oct. 2023 - Tmem161a regulates bone formation and bone strength through the P38 MAPK pathway.
Takuya Nagai; Tomohisa Sekimoto; Syuji Kurogi; Tomomi Ohta; Shihoko Miyazaki; Yoichiro Yamaguchi; Takuya Tajima; Etsuo Chosa; Mai Imasaka; Kumiko Yoshinobu; Kimi Araki; Masatake Araki; Narantsog Choijookhuu; Katsuaki Sato; Yoshitaka Hishikawa; Taro Funamoto
Scientific reports, Sep. 2023 - Reg family proteins contribute to inflammation and pancreatic stellate cells activation in chronic pancreatitis.
Wenting Chen; Mai Imasaka; Miyu Lee; Hirokazu Fukui; Hiroshi Nishiura; Masaki Ohmuraya
Scientific reports, Jul. 2023 - Double deficiency of cathepsin B and L in the mouse pancreas alters trypsin activity without affecting acute pancreatitis severity
Wenting Chen; Mai Imasaka; Hideaki Iwama; Hiroshi Nishiura; Masaki Ohmuraya
Pancreatology, Nov. 2022 - I536T variant of RBM20 affects splicing of cardiac structural proteins that are causative for developing dilated cardiomyopathy
Takuma Yamamoto; Rie Sano; Aya Miura; Mai Imasaka; Yoshiro Naito; Minori Nishiguchi; Kensuke Ihara; Naruhito Otani; Yoshihiko Kominato; Masaki Ohmuraya; Hidehito Kuroyanagi; Hajime Nishio
Journal of Molecular Medicine, Oct. 2022 - EPLINβ Is Involved in the Assembly of Cadherin-catenin Complexes in Osteoblasts and Affects Bone Formation
Shihoko Miyazaki; Taro Funamoto; Tomohisa Sekimoto; Syuji Kurogi; Tomomi Ohta; Takuya Nagai; Takuya Tajima; Mai Imasaka; Kumiko Yoshinobu; Kimi Araki; Masatake Araki; Narantsog Choijookhuu; Yoshitaka Hishikawa; Etsuo Chosa
ACTA HISTOCHEMICA ET CYTOCHEMICA, Jun. 2022 - Immune Aging and How It Works for Inflammation and Fibrosis
Hiroshi Nishiura; Mai Imasaka; Koji Yamanegi; Jiro Fujimoto; Masaki Ohmuraya
Frontiers in Physiology, Jan. 2022 - LincRNA-p21 exon 1 expression correlates with Cdkn1a expression in vivo.
Riki Furuhata; Mai Imasaka; Michihiko Sugimoto; Kumiko Yoshinobu; Masatake Araki; Kimi Araki
Genes to cells : devoted to molecular & cellular mechanisms, Jan. 2022 - Gene trapping reveals a new transcriptionally active genome element: The chromosome‐specific clustered trap region
Iyo Takeda; Masatake Araki; Kei‐ichiro Ishiguro; Toshinori Ohga; Kouki Takada; Yusuke Yamaguchi; Koichi Hashimoto; Takuma Kai; Naomi Nakagata; Mai Imasaka; Kumiko Yoshinobu; Kimi Araki
Genes to Cells, Aug. 2021 - The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis.
Michio Sato; Tsuyoshi Kadomatsu; Keishi Miyata; Junco S Warren; Zhe Tian; Shunshun Zhu; Haruki Horiguchi; Aman Makaju; Anna Bakhtina; Jun Morinaga; Taichi Sugizaki; Kaname Hirashima; Kumiko Yoshinobu; Mai Imasaka; Masatake Araki; Yoshihiro Komohara; Tomohiko Wakayama; Shinichi Nakagawa; Sarah Franklin; Koichi Node; Kimi Araki; Yuichi Oike
Nature communications, May 2021 - Cathepsin B and D deficiency in the mouse pancreas induces impaired autophagy and chronic pancreatitis.
Hideaki Iwama; Sally Mehanna; Mai Imasaka; Shinsuke Hashidume; Hiroshi Nishiura; Ken-Ichi Yamamura; Chigure Suzuki; Yasuo Uchiyama; Etsuro Hatano; Masaki Ohmuraya
Scientific reports, Mar. 2021 - Insulin2Q104del (Kuma) mutant mice develop diabetes with dominant inheritance.
Daisuke Sakano; Airi Inoue; Takayuki Enomoto; Mai Imasaka; Seiji Okada; Mutsumi Yokota; Masato Koike; Kimi Araki; Shoen Kume
Scientific reports, Jul. 2020 - Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.
Syuji Kurogi; Tomohisa Sekimoto; Taro Funamoto; Tomomi Ota; Shihoko Nakamura; Takuya Nagai; Mai Nakahara; Kumiko Yoshinobu; Kimi Araki; Masatake Araki; Etsuo Chosa
Scientific reports, Jan. 2017, [Reviewed] - Two transgenic mouse models for β-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations.
Gergely Kacso; Dora Ravasz; Judit Doczi; Beáta Németh; Ory Madgar; Ann Saada; Polina Ilin; Chaya Miller; Elsebet Ostergaard; Iordan Iordanov; Daniel Adams; Zsuzsanna Vargedo; Masatake Araki; Kimi Araki; Mai Nakahara; Haruka Ito; Aniko Gál; Mária J Molnár; Zsolt Nagy; Attila Patocs; Vera Adam-Vizi; Christos Chinopoulos
The Biochemical journal, Oct. 2016 - Database for exchangeable gene trap clones: Pathway and gene ontology analysis of exchangeable gene trap clone mouse lines
Masatake Araki; Mai Nakahara; Mayumi Muta; Miharu Itou; Chika Yanai; Fumika Yamazoe; Mikiko Miyake; Ayaka Morita; Miyuki Araki; Yoshiyuki Okamoto; Naomi Nakagata; Kumiko Yoshinobu; Ken-ichi Yamamura; Kimi Araki
DEVELOPMENT GROWTH & DIFFERENTIATION, Feb. 2014, [Reviewed] - Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice
Mai Nakahara; Hiroki Tateyama; Masatake Araki; Naomi Nakagata; Ken-Ichi Yamamura; Kimi Araki
Mammalian Genome, Jun. 2013, [Reviewed] - Ectopic Expression of Ptf1a Induces Spinal Defects, Urogenital Defects, and Anorectal Malformations in Danforth's Short Tail Mice
Kei Semba; Kimi Araki; Ken-ichirou Matsumoto; Hiroko Suda; Takashi Ando; Akira Sei; Hiroshi Mizuta; Katsumasa Takagi; Mai Nakahara; Mayumi Muta; Gen Yamada; Naomi Nakagata; Aritoshi Iida; Shiro Ikegawa; Yusuke Nakamura; Masatake Araki; Kuniya Abe; Ken-ichi Yamamura
PLoS Genetics, Feb. 2013, [Reviewed] - Defective Development of the Gall Bladder and Cystic Duct in Lgr4- Hypomorphic Mice
Ryo Yamashita; Yumiko Takegawa; Machiko Sakumoto; Mai Nakahara; Haruna Kawazu; Takayuki Hoshii; Kimi Araki; Yuji Yokouchi; Ken-Ichi Yamamura
DEVELOPMENTAL DYNAMICS, Apr. 2009, [Reviewed]
Research Themes
- Analysis of pathogenic alveolar macrophages which release IL-1alpha in response to fine particles.
Grant-in-Aid for Scientific Research (B)
Hyogo Medical University
01 Apr. 2023 - 31 Mar. 2026 - 新規糖尿病モデル:lincRNA-p21 過剰発現マウスにおける p21 転写亢進機序の解明
Apr. 2023 - Mar. 2024 - 新規糖尿病モデル：lincRNA-p21過剰発現マウスの解析
2021 - CRISPR/Cas9システムを用いた遺伝子変異細胞・マウスの作出とゲノム編集技術の開発
Apr. 2018 - Mar. 2019 - 内在性遺伝子座に過剰に発現したlincRNA-p21が糖尿病を引き起こす機序の解明
2016
