Last Updated :2025/08/16
Researcher Information
Research activity information
Paper
- Anti-transferrin receptor 1 antibody reduces angiotensin II-induced vascular remodeling
Naito Y.; Tsujino T.; Matsuura T.; Asakura M.; Masuyama T.; Ishihara M.
J Mol Cell Cardiol, Jun. 2025, [Reviewed] - Increased Red Cell Superoxide Dismutase Activity Is Associated with Cancer Risk: A Hidaka Cohort Study
Shin-ichiro Tanaka; Yoshio Fujioka; Takeshi Tsujino; Tatsuro Ishida; Ken-ichi Hirata
CANCER RESEARCH COMMUNICATIONS, Nov. 2024, [Reviewed] - Hypoxia-inducible factor-prolyl hydroxylase inhibitor Roxadustat (FG-4592) reduces renal fibrosis in Dahl salt-sensitive rats.
Yoshiro Naito; Seiki Yasumura; Keisuke Okuno; Masanori Asakura; Takeshi Tsujino; Tohru Masuyama; Masaharu Ishihara
Journal of hypertension, Mar. 2024 - Dimethyl Fumarate Ameliorated Cardiorenal Anemia Syndrome and Improved Overall Survival in Dahl/Salt-Sensitive Rats.
Satoyasu Ito; Fuyuka Yamatani; Yuri Arai; Eri Manabe; Takeshi Tsujino
The Journal of pharmacology and experimental therapeutics, Dec. 2023 - Iron Deficiency Induces Heart Failure With Ectopic Cardiac Calcification in Mice With Metabolic Syndrome.
Yoshiro Naito; Hisashi Sawada; Seiki Yasumura; Tetsuo Horimatsu; Keisuke Okuno; Saki Tahara; Koichi Nishimura; Masanori Asakura; Takeshi Tsujino; Tohru Masuyama; Masaharu Ishihara
Circulation. Heart failure, Jul. 2022 - Reactive Oxygen Species Cause Exercise-Induced Angina in a Myocardial Ischaemia-Reperfusion Injury Model.
Xiaohang Wang; Hirosato Kanda; Takeshi Tsujino; Yoko Kogure; Feng Zhu; Satoshi Yamamoto; Taichi Sakaguchi; Koichi Noguchi; Yi Dai
International journal of molecular sciences, Mar. 2022 - Crosstalk between Iron and Arteriosclerosis.
Yoshiro Naito; Takeshi Tsujino; Tohru Masuyama; Masaharu Ishihara
Journal of atherosclerosis and thrombosis, Mar. 2022 - Juzentaihoto improves adenine-induced chronic renal failure in BALB/c mice via suppression of renal fibrosis and inflammation.
Satoyasu Ito; Eri Manabe; Yi Dai; Masaharu Ishihara; Takeshi Tsujino
Journal of pharmacological sciences, Jan. 2022 - Association between urinary N-acetyl-β-glucosaminidase activity-urinary creatinine concentration ratio and risk of disability and all-cause mortality.
Shin-Ichiro Tanaka; Yoshio Fujioka; Takeshi Tsujino; Tatsuro Ishida; Ken-Ichi Hirata
PloS one, 2022 - Low Quality of Warfarin Therapy is Associated With Female Gender but Not With Polypharmacy in Patients With Atrial Fibrillation.
Kojiro Takamoto; Jun-Ichi Sakamoto; Satoyasu Ito; Takeshi Kimura; Eri Manabe; Toshiyuki Shikata; Masanori Asakura; Masaharu Ishihara; Takeshi Tsujino
Frontiers in pharmacology, 2021 - Reduced lifespan of erythrocytes in Dahl/Salt sensitive rats is the cause of the renal proximal tubule damage.
Eri Manabe; Satoyasu Ito; Yoshiya Ohno; Toshiyuki Tanaka; Yoshiro Naito; Naoko Sasaki; Masanori Asakura; Tohru Masuyama; Masaharu Ishihara; Takeshi Tsujino
Scientific reports, Dec. 2020 - Polypharmacy Is Associated With Accelerated Deterioration of Renal Function in Cardiovascular Outpatients.
Jun-Ichi Sakamoto; Toshiyuki Shikata; Satoyasu Ito; Takeshi Kimura; Kojiro Takamoto; Eri Manabe; Masanori Asakura; Masaharu Ishihara; Takeshi Tsujino
Cardiology research, Feb. 2020 - Reduction in Left Ventricular Ejection Fraction is Associated with Subsequent Cardiac Events in Outpatients with Chronic Heart Failure.
Yoshitaka Okuhara; Masanori Asakura; Yoshiyuki Orihara; Daisuke Morisawa; Yuki Matsumoto; Yoshiro Naito; Takeshi Tsujino; Masaharu Ishihara; Tohru Masuyama
Scientific reports, Nov. 2019 - Neutrophil/lymphocyte ratio elevation in renal dysfunction is caused by distortion of leukocyte hematopoiesis in bone marrow.
Satoyasu Ito; Yoshiya Ohno; Toshiyuki Tanaka; Shuhei Kobuchi; Kazuhide Ayajiki; Eri Manabe; Tohru Masuyama; Sakamoto Jun-Ichi; Takeshi Tsujino
Renal failure, Nov. 2019, [Reviewed] - Influence of quality of sleep in the first trimester on blood pressure in the third trimester in primipara women.
Kimie Okada; Izumi Saito; Chihiro Katada; Takeshi Tsujino
Blood pressure, Oct. 2019 - Effects of Weight Loss in Outpatients With Mild Chronic Heart Failure: Findings From the J-MELODIC Study.
Yoshitaka Okuhara; Masanori Asakura; Yoshiyuki Orihara; Yoshiro Naito; Takeshi Tsujino; Masaharu Ishihara; Tohru Masuyama
Journal of cardiac failure, Jan. 2019 - Altered expression of intestinal duodenal cytochrome b and divalent metal transporter 1 might be associated with cardio-renal anemia syndrome
Yoshiro Naito; Hisashi Sawada; Makiko Oboshi; Keisuke Okuno; Seiki Yasumura; Yoshitaka Okuhara; Akiyo Eguchi; Koichi Nishimura; Yuko Soyama; Masanori Asakura; Masaharu Ishihara; Takeshi Tsujino; Tohru Masuyama
Heart and Vessels, Nov. 2017 - Changes in brain natriuretic peptide in chronic heart failure patients treated with long-acting versus short-acting loop diuretics: J-MELODIC subanalysis.
Miho Fukui; Takeshi Tsujino; Shinichi Hirotani; Hiroshi Ito; Kazuhiro Yamamoto; Takashi Akasaka; Yutaka Hirano; Nobuyuki Ohte; Takashi Daimon; Satoshi Nakatani; Masaaki Kawabata; Tohru Masuyama
Heart and vessels, Jul. 2017, [Reviewed] - Attenuation of hypertension and renal damage in renovascular hypertensive rats by iron restriction
Makiko Oboshi; Yoshiro Naito; Hisashi Sawada; Toshihiro Iwasaku; Yoshitaka Okuhara; Akiyo Eguchi; Shinichi Hirotani; Toshiaki Mano; Takeshi Tsujino; Tohru Masuyama
HYPERTENSION RESEARCH, Dec. 2016, [Reviewed] - Long-term effects of L- and N-type calcium channel blocker on uric acid levels and left atrial volume in hypertensive patients
Mitsuru Masaki; Toshiaki Mano; Akiyo Eguchi; Shohei Fujiwara; Masataka Sugahara; Shinichi Hirotani; Takeshi Tsujino; Kazuo Komamura; Masahiro Koshiba; Tohru Masuyama
HEART AND VESSELS, Nov. 2016, [Reviewed] - Transferrin Receptor 1 in Chronic Hypoxia-Induced Pulmonary Vascular Remodeling
Yoshiro Naito; Manami Hosokawa; Hisashi Sawada; Makiko Oboshi; Shinichi Hirotani; Toshihiro Iwasaku; Yoshitaka Okuhara; Daisuke Morisawa; Akiyo Eguchi; Koichi Nishimura; Yuko Soyama; Kenichi Fujii; Toshiaki Mano; Masaharu Ishihara; Takeshi Tsujino; Tohru Masuyama
AMERICAN JOURNAL OF HYPERTENSION, Jun. 2016, [Reviewed] - Changes in collagen metabolism account for ventricular functional recovery following beta-blocker therapy in patients with chronic heart failure
Miho Fukui; Akiko Goda; Kazuo Komamura; Ayumi Nakabo; Mitsuru Masaki; Chikako Yoshida; Shinichi Hirotani; Masaaki Lee-Kawabata; Takeshi Tsujino; Toshiaki Mano; Tohru Masuyama
HEART AND VESSELS, Feb. 2016, [Reviewed] - Cardiac remodeling in response to chronic iron deficiency: role of the erythropoietin receptor
Yoshiro Naito; Hisashi Sawada; Makiko Oboshi; Toshihiro Iwasaku; Yoshitaka Okuhara; Daisuke Morisawa; Akiyo Eguchi; Shinichi Hirotani; Toshiaki Mano; Takeshi Tsujino; Tohru Masuyama
JOURNAL OF HYPERTENSION, Jun. 2015, [Reviewed] - Use of proton pump inhibitors is associated with anemia in cardiovascular outpatients.
Toshiyuki Shikata; Naoko Sasaki; Masahiro Ueda; Takeshi Kimura; Kanako Itohara; Masataka Sugahara; Miho Fukui; Eri Manabe; Tohru Masuyama; Takeshi Tsujino
Circulation journal : official journal of the Japanese Circulation Society, 2015 - Nuclear Factor-kappa B-Hypoxia-Inducible Factor-2 Pathway in Aortic Valve Stenosis
Hirokuni Akahori; Takeshi Tsujino; Yoshiro Naito; Hisashi Sawada; Masataka Sugahara; Miho Fukui; Mitsumasa Ohyanagi; Masataka Mitsuno; Yuji Miyamoto; Tohru Masuyama
JOURNAL OF HEART VALVE DISEASE, Sep. 2014, [Reviewed] - Atorvastatin ameliorates cardiac fibrosis and improves left ventricular diastolic function in hypertensive diastolic heart failure model rats
Hirokuni Akahori; Takeshi Tsujino; Yoshiro Naito; Mika Matsumoto; Naoko Sasaki; Toshihiro Iwasaku; Akiyo Eguchi; Hisashi Sawada; Shinichi Hirotani; Tohru Masuyama
JOURNAL OF HYPERTENSION, Jul. 2014, [Reviewed] - Elevated Arterial Stiffness and Diastolic Dysfunction in Subclinical Hypothyroidism
Mitsuru Masaki; Kazuo Komamura; Akiko Goda; Shinichi Hirotani; Misato Otsuka; Ayumi Nakabo; Miho Fukui; Shohei Fujiwara; Masataka Sugahara; Masaaki Lee-Kawabata; Takeshi Tsujino; Masahiro Koshiba; Tohru Masuyama
CIRCULATION JOURNAL, Jun. 2014, [Reviewed] - Long-term effects of irbesartan on plasma aldosterone concentration and left atrial volume in hypertensive patients
Mitsuru Masaki; Kazuo Komamura; Akiko Goda; Shinichi Hirotani; Misato Otsuka; Ayumi Nakabo; Miho Fukui; Shohei Fujiwara; Masataka Sugahara; Masaaki Lee-Kawabata; Takeshi Tsujino; Masahiro Koshiba; Tohru Masuyama
JOURNAL OF CARDIOLOGY, Mar. 2014, [Reviewed] - The impairment of the parasympathetic modulation is involved in the age-related change in mitral E/A ratio
Ayumi Nakabo; Akiko Goda; Mitsuru Masaki; Misato Otsuka; Chikako Yoshida; Akiyo Eguchi; Shinichi Hirotani; Masaaki Lee-Kawabata; Takeshi Tsujino; Tohru Masuyama
Heart and Vessels, 2014 - Beta-blocker stress echocardiography in an aortic stenosis patient with associated left ventricular outflow tract obstruction
Masataka Sugahara; Akiko Goda; Mitsuru Masaki; Ayumi Nakabo; Shohei Fujiwara; Miho Fukui; Kanako Itohara; Shinichi Hirotan; Kazuo Komamura; Masaaki Kawabata-Lee; Takeshi Tsujino; Tohru Masuyama
Journal of Echocardiography, 2014, [Reviewed] - Increased Renal Iron Accumulation in Hypertensive Nephropathy of Salt-Loaded Hypertensive Rats
Yoshiro Naito; Hisashi Sawada; Makiko Oboshi; Aya Fujii; Shinichi Hirotani; Toshihiro Iwasaku; Yoshitaka Okuhara; Akiyo Eguchi; Daisuke Morisawa; Mitsumasa Ohyanagi; Takeshi Tsujino; Tohru Masuyama
PLOS ONE, Oct. 2013, [Reviewed] - Intraleaflet haemorrhage as a mechanism of rapid progression of stenosis in bicuspid aortic valve
Hirokuni Akahori; Takeshi Tsujino; Yoshiro Naito; Chikako Yoshida; Masaaki Lee-Kawabata; Mitsumasa Ohyanagi; Masataka Mitsuno; Yuji Miyamoto; Takashi Daimon; Tohru Masuyama
International Journal of Cardiology, Jul. 2013, [Reviewed] - Dietary iron restriction prevents further deterioration of renal damage in a chronic kidney disease rat model
Yoshiro Naito; Aya Fujii; Hisashi Sawada; Shinichi Hirotani; Toshihiro Iwasaku; Yoshitaka Okuhara; Akiyo Eguchi; Mitsumasa Ohyanagi; Takeshi Tsujino; Tohru Masuyama
Journal of Hypertension, Jun. 2013, [Reviewed] - Impact of dietary iron restriction on the development of monocrotaline-induced pulmonary vascular remodeling and right ventricular failure in rats
Yoshiro Naito; Manami Hosokawa; Hiroyuki Hao; Hisashi Sawada; Shinichi Hirotani; Toshihiro Iwasaku; Yoshitaka Okuhara; Akiyo Eguchi; Seiichi Hirota; Mitsumasa Ohyanagi; Takeshi Tsujino; Tohru Masuyama
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jun. 2013, [Reviewed] - Iron restriction prevents diabetic nephropathy in Otsuka Long-Evans Tokushima fatty rat
Mika Matsumoto; Naoko Sasaki; Takeshi Tsujino; Hirokuni Akahori; Yoshiro Naito; Tohru Masuyama
RENAL FAILURE, 2013, [Reviewed] - Effect of iron restriction on renal damage and mineralocorticoid receptor signaling in a rat model of chronic kidney disease
Yoshiro Naito; Aya Fujii; Hisashi Sawada; Shinichi Hirotani; Toshihiro Iwasaku; Akiyo Eguchi; Mitsumasa Ohyanagi; Takeshi Tsujino; Tohru Masuyama
JOURNAL OF HYPERTENSION, Nov. 2012, [Reviewed] - Anemia in chronic heart failure: Mechanisms and treatment options
Takeshi Tsujino; Yoshiro Naito; Tohru Masuyama
Japanese Journal of Clinical Pharmacology and Therapeutics, 2012, [Reviewed] - Superiority of long-acting to short-acting loop diuretics in the treatment of congestive heart failure - The J-MELODIC study -
Tohru Masuyama; Takeshi Tsujino; Hideki Origasa; Kazuhiro Yamamoto; Takashi Akasaka; Yutaka Hirano; Nobuyuki Ohte; Takashi Daimon; Satoshi Nakatani; Hiroshi Ito
Circulation Journal, 2012, [Reviewed] - Determinants of plasma brain natriuretic peptide levels in untreated hypertensive patients
Akiko Goda; Shinji Nakao; Takeshi Tsujino; Masao Yuba; Misato Otsuka; Mika Matsumoto; Chikako Yoshida; Yoshiro Naito; Masaaki Lee-Kawabata; Mitsumasa Ohyanagi; Tohru Masuyama
Journal of Echocardiography, Sep. 2011, [Reviewed] - Endothelium-dependent coronary vasomotor response and neointimal coverage of zotarolimus-eluting stents 3 months after implantation
Kenichi Fujii; Daizo Kawasaki; Katsumi Oka; Hirokuni Akahori; Masashi Fukunaga; Hisashi Sawada; Motomaru Masutani; Masaaki Lee-Kawabata; Takeshi Tsujino; Mitsumasa Ohyanagi; Tohru Masuyama
HEART, Jun. 2011, [Reviewed] - The Impact of Pravastatin Pre-Treatment on Periprocedural Microcirculatory Damage in Patients Undergoing Percutaneous Coronary Intervention
Kenichi Fujii; Daizo Kawasaki; Katsumi Oka; Hirokuni Akahori; Toshihiro Iwasaku; Masashi Fukunaga; Akiyo Eguchi; Hisashi Sawada; Motomaru Masutani; Masaaki Lee-Kawabata; Takeshi Tsujino; Mitsumasa Ohyanagi; Tohru Masuyama
JACC-CARDIOVASCULAR INTERVENTIONS, May 2011, [Reviewed] - Administration of angiotensin-converting enzyme inhibitors is associated with slow progression of mild aortic stenosis in Japanese patients
Kana Wakabayashi; Takeshi Tsujino; Yoshiro Naito; Akira Ezumi; Masaaki Lee-Kawabata; Shinji Nakao; Akiko Goda; Yasushi Sakata; Kazuhiro Yamamoto; Takashi Daimon; Tohru Masuyama
Heart and Vessels, May 2011, [Reviewed] - Intraleaflet haemorrhage is associated with rapid progression of degenerative aortic valve stenosis.
Hirokuni Akahori; Takeshi Tsujino; Yoshiro Naito; Mika Matsumoto; Masaaki Lee-Kawabata; Mitsumasa Ohyanagi; Masataka Mitsuno; Yuji Miyamoto; Takashi Daimon; Hiroyuki Hao; Seiichi Hirota; Tohru Masuyama
European heart journal, Apr. 2011, [Reviewed] - Impaired expression of duodenal iron transporters in Dahl salt-sensitive heart failure rats
Yoshiro Naito; Takeshi Tsujino; Yoshihiro Fujimori; Hisashi Sawada; Hirokuni Akahori; Shinichi Hirotani; Mitsumasa Ohyanagi; Tohru Masuyama
JOURNAL OF HYPERTENSION, Apr. 2011, [Reviewed] - Dietary Iron Restriction Prevents Hypertensive Cardiovascular Remodeling in Dahl Salt-Sensitive Rats
Yoshiro Naito; Shinichi Hirotani; Hisashi Sawada; Hirokuni Akahori; Takeshi Tsujino; Tohru Masuyama
HYPERTENSION, Mar. 2011, [Reviewed] - Role of plasma aldosterone concentration in regression of left-ventricular mass following antihypertensive medication
Chikako Yoshida; Akiko Goda; Yoshiro Naito; Ayumi Nakaboh; Mika Matsumoto; Misato Otsuka; Mitsumasa Ohyanagi; Shinichi Hirotani; Masaaki Lee-Kawabata; Takeshi Tsujino; Tohru Masuyama
JOURNAL OF HYPERTENSION, Feb. 2011, [Reviewed] - Spherical ventricular chamber is a predictor of poor prognosis of heart failure with preserved ejection fraction
Akiyo Eguchi; Ayumi Nakaboh; Akiko Goda; Mitsuru Masaki; Misato Otsuka; Chikako Yoshida; Shinichi Hirotani; Lee-Kawabata Masaaki; Takeshi Tsujino; Tohru Masuyama
choonpa igaku, 2011, [Reviewed] - Preprocedural Evaluation and Endovascular Treatment of Iliofemoral Artery Disease Without Contrast Media for Patients With Pre-Existing Renal Insufficiency
Daizo Kawasaki; Kenichi Fujii; Masashi Fukunaga; Naohiko Fujii; Motomaru Masutani; Masaaki Lee Kawabata; Takeshi Tsujino; Mitsumasa Ohyanagi; Tohru Masuyama
CIRCULATION JOURNAL, Jan. 2011, [Reviewed] - Characterization of Cardiac Size and Function in SHRSP Z-Lepr(fa)/IzmDmcr Rats, a New Animal Model of Metabolic Syndrome
Yukari Tada; Satomi Kagota; Mika Matsumoto; Yoshiro Naito; Hiromi Shibata; Namie Nejime; Takeshi Tsujino; Masahiro Koshiba; Tohru Masuyama; Kazumasa Shinozuka
BIOLOGICAL & PHARMACEUTICAL BULLETIN, Dec. 2010, [Reviewed] - Decrease in serum adiponectin levels in response to treatment predicts good prognosis in acute decompensated heart failure.
Matsumoto M; Lee-Kawabata M; Tsujino T; Naito Y; Ezumi A; Sakoda T; Ohyanagi M; Shimomura I; Masuyama T
Journal of clinical hypertension (Greenwich, Conn.), Nov. 2010, [Reviewed] - Increase in tissue and circulating pentraxin3 levels in patients with aortic valve stenosis
Yoshiro Naito; Takeshi Tsujino; Hirokuni Akahori; Mitsumasa Ohyanagi; Masataka Mitsuno; Yuji Miyamoto; Hiroyuki Hao; Seiichi Hirota; Tohru Masuyama
AMERICAN HEART JOURNAL, Oct. 2010, [Reviewed] - Serum interleukin-6 and C-reactive protein are markedly elevated in acute decompensated heart failure patients with left ventricular systolic dysfunction
Mika Matsumoto; Takeshi Tsujino; Masaaki Lee-Kawabata; Yoshiro Naito; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Tohru Masuyama
CYTOKINE, Mar. 2010, [Reviewed] - OCT Assessment of Thin-Cap Fibroatheroma Distribution in Native Coronary Arteries
Kenichi Fujii; Daizo Kawasaki; Motomaru Masutani; Takahiro Okumura; Takafumi Akagami; Tsuyoshi Sakoda; Takeshi Tsujino; Mitsumasa Ohyanagi; Tohru Masuyama
JACC-CARDIOVASCULAR IMAGING, Feb. 2010, [Reviewed] - Iron Regulatory Hormone Hepcidin Decreases in Chronic Heart Failure Patients With Anemia
Mika Matsumoto; Takeshi Tsujino; Masaaki Lee-Kawabata; Yoshiro Naito; Hirokuni Akahori; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Naohisa Tomosugi; Tohru Masuyama
CIRCULATION JOURNAL, Feb. 2010, [Reviewed] - HYPERGLYCEMIA INDUCED CELL GROWTH AND GENE EXPRESSION VIA THE SERUM RESPONSE ELEMENT THROUGH RhoA AND Rho-KINASE IN VASCULAR SMOOTH MUSCLE CELLS
Kai Ishiko; Tsuyoshi Sakoda; Takahumi Akagami; Toshio Naka; Takashi Doi; Takeshi Tsujino; Tohru Masuyama; Mitsumasa Ohyanagi
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, 2010, [Reviewed] - The Mechanism of Distinct Diurnal Variations of Renin-Angiotensin System in Aorta and Heart of Spontaneously Hypertensive Rats
Yoshiro Naito; Takeshi Tsujino; Mika Matsumoto; Satoshi Okuda; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Tohru Masuyama
CLINICAL AND EXPERIMENTAL HYPERTENSION, Dec. 2009, [Reviewed] - Inappropriateness of ventricular hypertrophy is important as a determinant of BNP but not of diastolic filling in untreated hypertensive patients
Akiko Goda; Shinji Nakao; Takeshi Tsujino; Misato Otsuka; Mika Matsumoto; Chikako Yoshida; Yoshiro Naito; Masaaki Lee-Kawabata; Mitsumasa Ohyanagi; Tohru Masuyama
HYPERTENSION RESEARCH, Oct. 2009, [Reviewed] - Matrix metalloproteinase-1 and-2 levels are differently regulated in acute exacerbation of heart failure in patients with and without left ventricular systolic dysfunction
Yoshiro Naito; Takeshi Tsujino; Masaaki Lee-Kawabata; Mika Matsumoto; Akira Ezumi; Shinji Nakao; Akiko Goda; Mitsumasa Ohyanagi; Tohru Masuyama
HEART AND VESSELS, May 2009, [Reviewed] - Value of assessment of left atrial volume and diameter in patients with heart failure but with normal left ventricular ejection fraction and mitral flow velocity pattern
Chikako Yoshida; Shinji Nakao; Akiko Goda; Yoshiro Naito; Mika Matsumoto; Misato Otsuka; Miho Shimoshikiryo; Akiyo Eguchi; Masaaki Lee-Kawabata; Takeshi Tsujino; Tohru Masuyama
EUROPEAN JOURNAL OF ECHOCARDIOGRAPHY, Mar. 2009, [Reviewed] - Adaptive response of the heart to long-term anemia induced by iron deficiency
Yoshiro Naito; Takeshi Tsujino; Mika Matsumoto; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Tohru Masuyama
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, Mar. 2009, [Reviewed] - High Salt Intake Elevated Blood Pressure but not Changed Circadian Blood Pressure Rhythm in Otsuka Long-Evans Tokushima Fatty (OLETF) Rat
Mika Matsumoto; Takeshi Tsujino; Yoshiro Naito; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Hidemi Nonaka; Tohru Masuyama
CLINICAL AND EXPERIMENTAL HYPERTENSION, 2009, [Reviewed] - Symptomatic ventricular tachyarrhythmia is associated with delayed gadolinium enhancement in cardiac magnetic resonance imaging and with elevated plasma brain natriuretic peptide level in hypertrophic cardiomyopathy
Katsumi Oka; Takeshi Tsujino; Shinji Nakao; Masaaki Lee-Kawabata; Akira Ezumi; Miho Masai; Mitsumasa Ohyanagi; Tohru Masuyama
Journal of Cardiology, Oct. 2008, [Reviewed] - Aldosterone induces interleukin-18 through endothelin-1, angiotensin II, Rho/Rho-kinase, and PPARs in cardiomyocytes
Takashi Doi; Tsuyoshi Sakoda; Takafumi Akagami; Toshio Naka; Yoshitomo Mori; Takeshi Tsujino; Tohru Masuyama; Mitsumasa Ohyanagi
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, Sep. 2008, [Reviewed] - Anemia as a Factor That Elevates Plasma Brain Natriuretic Peptide Concentration in Apparently Healthy Subjects
Mika Matsumoto; Takeshi Tsujino; Yoshiro Naito; Masaaki Lee-Kawabata; Akira Ezumi; Kazuhiro Yamamoto; Toshiaki Mano; Tohru Masuyama
INTERNATIONAL HEART JOURNAL, Sep. 2008, [Reviewed] - Novel use of ultrasound guidance for recanalization of iliac, femoral, and popliteal arteries
Daizo Kawasaki; Takeshi Tsujino; Kenichi Fujii; Motomaru Masutani; Mitsumasa Ohyanagi; Tohru Masuyama
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, May 2008, [Reviewed] - Mechanical stretch induced interleukin-18 (IL-18) expression through angiotensin subtype 1 receptor (AT1R) and endothelin-1 in cardiomyocytes
Toshio Naka; Tsuyoshi Sakoda; Takashi Doi; Takafumi Akagami; Takeshi Tsujino; Tohru Masuyama; Mitsumasa Ohyanagi
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, 2008, [Reviewed] - Characterization of left ventricular filling abnormalities and its relation to elevated plasma brain natriuretic peptide level in acute to chronic Diastolic heart failure
Shinji Nakao; Akiko Goda; Masao Yuba; Misato Otsuka; Mika Matsumoto; Chikako Yoshida; Mitsumasa Ohyanagi; Yoshiro Naito; Masaaki Lee; Takeshi Tsujino; Tohru Masuyama
CIRCULATION JOURNAL, Sep. 2007, [Reviewed] - Rationale and design of a randomized trial to assess the effects of diuretics in heart failure - Japanese multicenter evaluation of long- vs short-acting diuretics in congestive heart failure (J-MELODIC)
Tohru Masuyama; Hiroshi Ito; Nobuyuki Ohte; Takashi Akasaka; Satoshi Nakatani; Yutaka Hirano; Kazuhiro Yamamoto; Mitsumasa Ohyanagi; Keiko Takahashi; Yutaka Takeda; Shinichi Fujimoto; Toshiaki Mano; Yoshio Yasumura; Hideki Origasa; Tatsuyuki Kakuma; Satoshi Hattori; Takeshi Tsujino; Masaaki Lee; Akira Kitabatake; Hirohide Matsuo; Toshihiko Morikawa
CIRCULATION JOURNAL, Jul. 2007, [Reviewed] - Two giant renal aneurysms and renal arteriovenous fistula associated with cardiac insufficiency and a sustained elevation of atrial natriuretic peptide and brain natriuretic peptide
Tsuyoshi Sakoda; Arisa Nishimukai; Takeshi Tsujino; Tohru Masuyama; Yuji Miyamoto; Mitsumasa Oyanagi
AMERICAN JOURNAL OF THE MEDICAL SCIENCES, May 2007, [Reviewed] - Role of activated renin-angiotensin system in myocardial fibrosis and left ventricular diastolic dysfunction in diabetic patients - Reversal by chronic angiotensin II type 1A receptor blockade
Daizo Kawasaki; Keisuke Kosugi; Hidehiko Waki; Kazuhiro Yamamoto; Takeshi Tsujino; Tohru Masuyama
CIRCULATION JOURNAL, Apr. 2007, [Reviewed] - Loop diuretic precipitated beriberi in a patient after pancreaticoduodenectomy: A case report
Takeshi Tsujino; Shinji Nakao; Kana Wakabayashi; Masaaki Lee; Takashi Kimura; Hiroo Yoshikawa; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Tohru Masuyama
American Journal of the Medical Sciences, 2007 - Left Ventricular Geometrical Characterization in Patients With Diastolic Heart Failure
Akiko Goda; Misato Otsuka; Mika Matsumoto; Chikako Yoshida; Akiyo Eguchi; Miho Shimoshikiryo; Yoshiro Naito; Masaaki Lee; Takeshi Tsujino; Tohru Masuyama
Journal of Echocardiography, 2007, [Reviewed] - Postgastrectomy beriberi exaggerated by diuretic use : A case report
Hirokuni Akahori; Takeshi Tsujino; Mitsuo Masutani; Takafumi Akagami; Keiji Tanabe; Miho Masai; Yoshio Fujioka; Mitsumasa Ohyanagi; Tohru Masuyama
Journal of Cardiology, 2007, [Reviewed] - Ultrasound enhances retrovirus-mediated gene transfer
Toshio Naka; Tsuyoshi Sakoda; Takashi Doi; Takeshi Tsujino; Tohru Masuyama; Seinosuke Kawashima; Tadaaki Iwasaki; Mitsumasa Ohyanagi
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, 2007, [Reviewed] - Inhibitory effect of insulin on vasopressin-induced intracellular calcium response is blunted in hyperinsulinemic hypertensive patients: role of membrane fatty acid composition.
Maekawa K; Tsujino T; Saito K; Kim JI; Ikeda Y; Emoto N; Yokoyama M
Heart and vessels, Jul. 2006, [Reviewed] - Chylomicron remnants stimulate release of interleukin-1 beta by THP-1 cells
Takahiro Okumura; Yoshio Fujioka; Shinji Morimoto; Miho Masai; Tsuyoshi Sakoda; Takeshi Tsujino; Shin-ichiro Kashiwamura; Haruki Okamura; Mitsumasa Ohyanagi
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, Feb. 2006, [Reviewed] - Mizoribine-induced rhabdomyolysis in a rheumatoid arthritis patient receiving bezafibirate treatment
S Morimoto; Y Fujioka; C Tsutsumi; M Masai; T Okumura; M Yuba; T Sakoda; T Tsujino; M Ohyanagi
AMERICAN JOURNAL OF THE MEDICAL SCIENCES, Apr. 2005, [Reviewed] - Cardiac wall motion abnormalities observed in a patient with transient hyperthyroidism
T Sakaki; Y Fujioka; T Akagami; M Masai; H Shimizu; T Sakoda; T Tsujino; M Ohyanagi
JAPANESE HEART JOURNAL, Nov. 2004, [Reviewed] - Candida parapsilosis endocarditis that emerged 2 years after abdominal surgery
Kazumi Tonomo; Takeshi Tsujino; Yoshio Fujioka; Shinji Nakao; Hideki Yao; Hitoshi Yasoshima; Akira Kubota; Tadaaki Iwasaki; Mitsumasa Ohyanagi
Heart and Vessels, May 2004 - Oral taurine supplementation prevents fructose-induced hypertension in rats.
Harada H; Tsujino T; Watari Y; Nonaka H; Emoto N; Yokoyama M
Heart and vessels, May 2004, [Reviewed] - Pulmonary Thromboembolism (PTE) in a Patient with Polycythemia Vera after Surgery for Acute Epidural Hematoma
Mitsuyo Kinoshita; Yoshio Fujioka; Shinji Nakao; Hiroki Shimizu; Masao Yuba; Shinji Morimoto; Tsuyoshi Sakoda; Takeshi Tsujino; Mahito Misawa; Kazuyoshi Tamura; Mitsumasa Ohyanagi
Journal of Medical Ultrasonics, Nov. 2003 - Circadian gene expression of clock genes and plasminogen activator inhibitor-1 in heart and aorta of spontaneously hypertensive and Wistar-Kyoto rats
Y Naito; T Tsujino; D Kawasaki; T Okumura; S Morimoto; M Masai; T Sakoda; Y Fujioka; M Ohyanagi; T Iwasaki
JOURNAL OF HYPERTENSION, Jun. 2003, [Reviewed] - Usefulness of circulating interleukin-18 concentration in acute myocardial infarction as a risk factor for late restenosis after emergency coronary angioplasty
D Kawasaki; T Tsujino; S Morimoto; Y Fujioka; Y Naito; T Okumura; M Masutani; H Shimizu; M Yuba; A Ueda; M Ohyanagi; S Kashiwamura; H Okamura; T Iwasaki
AMERICAN JOURNAL OF CARDIOLOGY, May 2003, [Reviewed] - Bezatibrate improves hypertension and insulin sensitivity in humans
JI Kim; T Tsujino; Y Fujioka; K Saito; M Yokoyama
HYPERTENSION RESEARCH, Apr. 2003, [Reviewed] - The renin-angiotensin system is involved in the production of plasminogen activator inhibitor type 1 by cultured endothelial cells in response to chylomicron remnants
S Morimoto; Y Fujioka; H Hosoai; T Okumura; M Masai; T Sakoda; T Tsujino; M Ohyanagi; T Iwasaki
HYPERTENSION RESEARCH, Apr. 2003, [Reviewed] - Troglitazone reduces activity of the Na+/H+ exchanger in fructose-fed borderline hypertensive rats
Y Fujioka; M Masai; S Tsuboi; T Okumura; S Morimoto; T Tsujino; M Ohyanagi; T Iwasaki
HYPERTENSION RESEARCH, Jan. 2003 - Augmented diurnal variations of the cardiac renin-angiotensin system in hypertensive rats
Y Naito; T Tsujino; Y Fujioka; M Ohyanagi; T Iwasaki
HYPERTENSION, Dec. 2002 - Eicosapentaenoic acid improves endothelial function in hypertriglyceridemic subjects despite increased lipid oxidizability
T Okumura; Y Fujioka; S Morimoto; S Tsuboi; M Masai; T Tsujino; M Ohyanagi; T Iwasaki
AMERICAN JOURNAL OF THE MEDICAL SCIENCES, Nov. 2002 - Increased circulating interleukin-18 in patients with congestive heart failure
Naito Y.; Tsujino T.; Fujioka Y.; Ohyanagi M.; Okamura H.; Iwasaki T.
Heart, Sep. 2002, [Reviewed]
Corresponding - Decreased ornithine decarboxylase activity in the kidneys of Dahl salt-sensitive rats
T Hayashi; T Tsujino; S Iwata; H Nonaka; N Emoto; Y Yano; S Otani; Y Hayashi; H Itoh; M Yokoyama
HYPERTENSION RESEARCH, Sep. 2002 - Decreased expression of arginase II in the kidneys of Dahl salt-sensitive rats
S Iwata; T Tsujino; Y Ikeda; T Ishida; T Ueyama; T Gotoh; M Mori; M Yokoyama
HYPERTENSION RESEARCH, May 2002 - Effects of eicosapentaenoic acid on blood pressure, cell membrane fatty acids, and intracellular sodium concentration in essential hypertension
T Miyajima; T Tsujino; K Saito; M Yokoyama
HYPERTENSION RESEARCH, Sep. 2001 - Taurine prevents the decrease in expression and secretion of extracellular superoxide dismutase induced by homocysteine - Amelioration of homocysteine-induced endoplasmic reticulum stress by taurine
H Nonaka; T Tsujino; Y Watari; N Emoto; M Yokoyama
CIRCULATION, Sep. 2001 - Oral taurine supplementation prevents the development of ethanol-induced hypertension in rats
H Harada; K Kitazaki; T Tsujino; Y Watari; S Iwata; H Nonaka; T Hayashi; T Takeshita; K Morimoto; M Yokoyama
HYPERTENSION RESEARCH, May 2000 - Genotype--Phenotype Correlation of Patients with Multiple Endocrine Neoplasia Type 2 in Japan
S.-i. Egawa; H. Futami; K. Takasaki; M. Iihara; T. Okamoto; M. Kanbe; T. Ohi; Y. Saio; A. Miyauchi; Y. Takiyama; M. Koga; K. Miyanaga; K.-i. Inoue; S. Mitsuyama; Y. Nomura; H. Takei; S. Mugiya; O. Ishida; F. Zeze; S. Shakutsui; H. Inoue; H. Oya; A. Yoshimura; S. Ishizuka; T. Tsujino; T. Obara; K. Yamaguchi
Japanese Journal of Clinical Oncology, Oct. 1998, [Reviewed] - ALPHA-SUBSPECIES, BETA-II-SUBSPECIES AND GAMMA-SUBSPECIES OF PROTEIN-KINASE-C LOCALIZED IN THE MONKEY HIPPOCAMPUS - PRESYNAPTIC AND POSTSYNAPTIC LOCALIZATION OF GAMMA-SUBSPECIES
N SAITO; T TSUJINO; K FUKUDA; C TANAKA
BRAIN RESEARCH, Sep. 1994 - CALCIUM SUPPLEMENTATION INHIBITS THE EXPRESSION OF PARATHYROID HYPERTENSIVE FACTOR IN DOCA-SALT HYPERTENSIVE RATS
CM LIN; K SAITO; T TSUJINO; M YOKOYAMA
AMERICAN JOURNAL OF HYPERTENSION, Feb. 1994 - MOLECULAR-STRUCTURE AND TRANSCRIPTIONAL FUNCTION OF THE RAT VASCULAR AT(1A) ANGIOTENSIN RECEPTOR GENE
K TAKEUCHI; RW ALEXANDER; Y NAKAMURA; T TSUJINO; TJ MURPHY
CIRCULATION RESEARCH, Oct. 1993 - IMMUNOCYTOCHEMICAL LOCALIZATION OF ALPHA-SUBSPECIES, BETA-I-SUBSPECIES, BETA-II-SUBSPECIES AND GAMMA-SUBSPECIES OF PROTEIN-KINASE-C IN THE MOTOR AND PREMOTOR CORTICES OF THE RHESUS-MONKEY
S TOMINAGA; N SAITO; T TSUJINO; C TANAKA
NEUROSCIENCE RESEARCH, May 1993, [Reviewed] - EXPRESSION OF FOS-LIKE IMMUNOREACTIVITY BY YOHIMBINE AND CLONIDINE IN THE RAT-BRAIN
T TSUJINO; H SANO; Y KUBOTA; ST HSIEH; T MIYAJIMA; K SAITO; M NAKAJIMA; N SAITO; M YOKOYAMA
EUROPEAN JOURNAL OF PHARMACOLOGY-MOLECULAR PHARMACOLOGY SECTION, May 1992, [Reviewed]
Lead - Alpha2-adrenergic receptor mediated expression of c-Fos immunoreactivity in rat brain.
Tsujino T.; Sano H.; Kubota Y.; Hsieh ST; Miyajima T.; Yokoyama Y.
Ther Res, 1992
Lead - IMMUNOCYTOCHEMICAL LOCALIZATION OF PROTEIN-KINASE-C SUBSPECIES IN THE RAT SPINAL-CORD - LIGHT AND ELECTRON-MICROSCOPIC STUDY
M MORI; A KOSE; T TSUJINO; C TANAKA
JOURNAL OF COMPARATIVE NEUROLOGY, Sep. 1990, [Reviewed] - IMMUNOCYTOCHEMICAL LOCALIZATION OF THE ALPHA-SUBSPECIES OF PROTEIN KINASE-C IN RAT-BRAIN
A ITO; N SAITO; M HIRATA; A KOSE; T TSUJINO; C YOSHIHARA; K OGITA; A KISHIMOTO; Y NISHIZUKA; C TANAKA
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Apr. 1990, [Reviewed], [Invited] - LIGHT AND ELECTRON-MICROSCOPIC LOCALIZATION OF BETA-1-SUBSPECIES, BETA-II-SUBSPECIES, AND GAMMA-SUBSPECIES OF PROTEIN KINASE-C IN RAT CEREBRAL NEOCORTEX
T TSUJINO; A KOSE; N SAITO; C TANAKA
JOURNAL OF NEUROSCIENCE, Mar. 1990, [Reviewed]
Lead - IMMUNOCYTOCHEMICAL LOCALIZATION OF THE BETA-1-SUBSPECIES OF PROTEIN KINASE-C IN RAT-BRAIN
K HOSODA; N SAITO; A KOSE; A ITO; T TSUJINO; K OGITA; U KIKKAWA; Y ONO; K IGARASHI; Y NISHIZUKA; C TANAKA
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Feb. 1989, [Reviewed], [Invited]
MISC
- Mechanisms of aortic stenosis
Hirokuni Akahori; Takeshi Tsujino; Tohru Masuyama; Masaharu Ishihara
Journal of Cardiology, 01 Mar. 2018 - Cellular Iron Transport Protein, Transferrin Receptor 1 Plays an Important Role in the Pathophysiology of Chronic Kidney Disease
Makiko Oboshi; Yoshiro Naito; Hisashi Sawada; Toshihiro Iwasaku; Yoshitaka Okuhara; Daisuke Morisawa; Akiyo Eguchi; Koichi Nishimura; Yuko Soyama; Shinichi Hirotani; Toshiaki Mano; Masaharu Ishihara; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Nov. 2015 - DWS as an Index of Myocardial Stiffness and a Predictor of Heart Failure Outcome in Patients with Chronic Beta-blockade Therapy
Yuko Soyama; Toshiaki Mano; Shinichi Hirotani; Mitsuru Masaki; Miho Fukui; Shohei Fujiwara; Masataka Sugahara; Kazuo Komamura; Masaaki L. Kawabata; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Nov. 2014 - Iron Plays a Role in the Thrombus Formation of a Rat Model of Deep Vein Thrombosis
Makiko Oboshi; Yoshiro Naito; Hisashi Sawada; Toshihiro Iwasaku; Yoshitaka Okuhara; Daisuke Morisawa; Akiyo Eguchi; Shinichi Hirotani; Toshiaki Mano; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Nov. 2014 - Iron Restricted Pair Feeding Attenuates Hypertension and Renal Damage in a Rat Model of Chronic Kidney Disease
Yoshiro Naito; Hisashi Sawada; Makiko Oboshi; Aya Fujii; Manami Hosokawa; Toshihiro Iwasaku; Yoshitaka Okuhara; Daisuke Morisawa; Akiyo Eguchi; Shinichi Hirotani; Toshiaki Mano; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Nov. 2014 - Cellular Iron Transport Protein, Transferrin Receptor 1 Plays a Role in the Pathophysiology of Pulmonary Arterial Hypertension
Manani Hosokawa; Yoshiro Naito; Hisashi Sawada; Makiko Oboshi; Toshihiro Iwasaku; Yoshitaka Okuhara; Daisuke Morisawa; Akiyo Eguchi; Shinichi Hirotani; Toshiaki Mano; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Nov. 2014 - EFFECTS OF IRON RESTRICTION ON MONOCROTALINE-INDUCED PULMONARY VASCULAR REMODELING
Yoshiro Naito; Manami Hosokawa; Hiroyuki Hao; Hisashi Sawada; Makiko Oboshi; Toshihiro Iwasaku; Yoshitaka Okuhara; Daisuke Morisawa; Akiyo Eguchi; Shinichi Hirotani; Takeshi Tsujino; Tohru Masuyama
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Apr. 2014 - Hepcidin is increased in the hypertrophied heart of Dahl salt-sensitive rats
Yoshiro Naito; Manami Hosokawa; Hisashi Sawada; Makiko Oboshi; Toshihiro Iwasaku; Yoshitaka Okuhara; Daisuke Morisawa; Akiyo Eguchi; Shinichi Hirotani; Mitsumasa Ohyanagi; Takeshi Tsujino; Tohru Masuyama
INTERNATIONAL JOURNAL OF CARDIOLOGY, Mar. 2014 - Dietary Iron Restriction Attenuates Hypertension and Renal Injury in Aldosterone/Salt-Induced Hypertensive Mice
Hisashi Sawada; Yoshiro Naito; Makiko Oboshi; Toshihiro Iwasaku; Yoshitaka Okuhara; Daisuke Morisawa; Akiyo Eguchi; Shinichi Hirotani; Takeshi Tsujino; Mitsumasa Ohyanagi; Tohru Masuyama
CIRCULATION, Nov. 2013 - A Novel Index of Ventricular Stiffness Shows Recovery Following Induction of Beta-Blockade in Patients With Left Ventricular Systolic Dysfunction
Yuko Soyama; Shinichi Hirotani; Ayumi Nakabo; Akiko Goda; Mitsuru Masaki; Miho Fukui; Shohei Fujiwara; Masataka Sugahara; Kanako Itohara; Kazuo Komamura; Masaaki Lee-Kawabata; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Nov. 2013 - Association of Changes in Heart Rate and Collagen Metabolism by Beta-Blocker Therapy With Improvement in Left Ventricular Diastolic Function in Patients With Chronic Heart Failure
Miho Fukui; Kazuo Komamura; Ayumi Nakabo; Akiko Goda; Mitsuru Masaki; Chikako Yoshida; Shinichi Hirotani; Masaaki Lee-Kawabata; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Nov. 2013 - Angiotensin II type 1a receptor signaling is implicated in erythropoietin production in response to iron deficiency in mice
Yoshiro Naito; Hisashi Sawada; Shinichi Hirotani; Toshihiro Iwasaku; Yoshitaka Okuhara; Akiyo Eguchi; Kojiro Miki; Mitsumasa Ohyanagi; Takeshi Tsujino; Tohru Masuyama
International Journal of Cardiology, 30 Sep. 2013 - Expression of interleukin-33 and ST2 in nonrheumatic aortic valve stenosis
Hisashi Sawada; Yoshiro Naito; Shinichi Hirotani; Hirokuni Akahori; Toshihiro Iwasaku; Yoshitaka Okuhara; Kojiro Miki; Akiyo Eguchi; Masataka Mitsuno; Yuji Miyamoto; Mitsumasa Ohyanagi; Takeshi Tsujino; Tohru Masuyama
INTERNATIONAL JOURNAL OF CARDIOLOGY, Sep. 2013 - Neovascularization of stenotic aortic valve is associated with expression of nuclear factor-kappa B and hypoxia inducible factor-2 alpha
M. Sugahara; T. Tsujino; H. Akahori; Y. Naito; H. Sawada; M. Fukui; M. Ohyanagi; M. Mitsuno; Y. Miyamoto; T. Masuyama
EUROPEAN HEART JOURNAL, Aug. 2013 - Comparison of long- and short-acting diuretics in follow-up of patients with chronic heart failure
Tohru Masuyama; Takeshi Tsujino
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013 - Dietary Iron Restriction Prevents and Rescues Renal Injury in a Rat Model of Chronic Kidney Disease
Aya Fujii; Yoshiro Naito; Hisashi Sawada; Shinichi Hirotani; Toshihiro Iwasaku; Akiyo Eguchi; Yoshitaka Okuhara; Kojiro Miki; Mitsumasa Ohyanagi; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Nov. 2012 - Interleukin-33 and Soluble ST2 Are Expressed in Human Nonrheumatic Aortic Valve Stenosis
Hisashi Sawada; Yoshiro Naito; Shinichi Hirotani; Hirokuni Akahori; Toshihiro Iwasaku; Yoshitaka Okuhara; Kojiro Miki; Akiyo Eguchi; Masataka Mitsuno; Yuji Miyamoto; Masaaki L. Kawabata; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Nov. 2012 - Long-acting Loop Diuretic is Superior to Short-acting One in Treatment of Congestive Heart Failure: The J-MELODIC Study
Takeshi Tsujino; Tohru Masuyama
JOURNAL OF CARDIAC FAILURE, Oct. 2012 - T-type Ca2+channel antagonists attenuated aldosterone induces endothelin-1-Rho/Rho-kinase-interleukin-18 pathway in cardiomyocytes
T. Doi; T. Sakoda; T. Akagami; T. Naka; T. Tsujino; T. Masuyama; M. Ohyanagi
EUROPEAN HEART JOURNAL, Aug. 2012 - The Correlation Between Collagen Degradation and LV Function Following Induction of Beta-Blocker Therapy
Chikako Yoshida; Shinichi Hirotani; Akiko Goda; Mitsuru Masaki; Misato Otsuka; Ayumi Nakaboh; Akiyo Eguchi; Masaaki Lee-Kawabata; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Nov. 2011 - Involvement of bone morphogenetic protein-binding endothelial regulator in aortic valve stenosis
Hisashi Sawada; Yoshiro Naito; Shinichi Hirotani; Hirokuni Akahori; Toshihiro Iwasaku; Akiyo Eguchi; Yoshitaka Okuhara; Aya Fujii; Mitsumasa Ohyanagi; Masataka Mitsuno; Yuji Miyamoto; Takeshi Tsujino; Tohru Masuyama
INTERNATIONAL JOURNAL OF CARDIOLOGY, Oct. 2011 - Administration of Dual Calcium Channel Blocker, Efonidipine Enhances Benefits of Cardiac Rehabilitation in Patients with First Myocardial Infarction
Toshio Naka; Chikako Yoshida; Takafumi Akagami; Takashi Doi; Takeshi Tsujino; Tohru Masuyama; Mitsumasa Ohyanagi
JOURNAL OF CARDIAC FAILURE, Sep. 2011 - Statin use reduces neoangiogenesis and intraleaflet haemorrhage in the aortic valve of degenerative aortic stenosis
H. Akahori; T. Tsujino; Y. Naito; C. Yoshida; N. Sasaki; M. L. Kawabata; M. Ohyanagi; M. Mitsuno; Y. Miyamoto; T. Masuyama
EUROPEAN HEART JOURNAL, Aug. 2011 - Neoangiogenesis, intraleaflet haemorrhage and macrophage infiltration are more remarkable in bicuspid aortic valve stenosis than in tricuspid aortic valve stenosis
H. Akahori; T. Tsujino; Y. Naito; C. Yoshida; N. Sasaki; M. L. Kawabata; M. Ohyanagi; M. Mitsuno; Y. Miyamoto; T. Masuyama
EUROPEAN HEART JOURNAL, Aug. 2011 - Ventricular diastolic dysfunction in SHRSP.Z-Lepr(fa)/IzmDmcr rats, a model of metabolic syndrome
Yukari Tada; Satomi Kagota; Mika Matsumoto; Yoshiro Naito; Hiromi Shibata; Namie Nejime; Takeshi Tsujino; Masahiro Koshiba; Tohru Masuyama; Kazumasa Shinozuka
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011 - Statin use reduces neoangiogenesis and intraleaflet haemorrhage in the aortic valve of degenerative aortic stenosis
H. Akahori; T. Tsujino; Y. Naito; C. Yoshida; N. Sasaki; M. L. Kawabata; M. Ohyanagi; M. Mitsuno; Y. Miyamoto; T. Masuyama
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2011 - Neoangiogenesis, intraleaflet haemorrhage and macrophage infiltration are more remarkable in bicuspid aortic valve stenosis than in tricuspid aortic valve stenosis
H. Akahori; T. Tsujino; Y. Naito; C. Yoshida; N. Sasaki; M. L. Kawabata; M. Ohyanagi; M. Mitsuno; Y. Miyamoto; T. Masuyama
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2011 - Augmented cannabinoid receptors expression in human aortic valve stenosis
Yoshiro Naito; Takeshi Tsujino; Hirokuni Akahori; Mitsumasa Ohyanagi; Masataka Mitsuno; Yuji Miyamoto; Tohru Masuyama
INTERNATIONAL JOURNAL OF CARDIOLOGY, Dec. 2010 - Increased serum neopterin in patients with nonrheumatic aortic valve stenosis
Yoshiro Naito; Takeshi Tsujino; Hirokuni Akahori; Mika Matsumoto; Mitsumasa Ohyanagi; Masataka Mitsuno; Yuji Miyamoto; Tohru Masuyama
INTERNATIONAL JOURNAL OF CARDIOLOGY, Nov. 2010 - Association of Endothelium-dependent Coronary Vasomotor Response and Neointimal Coverage of Zotarolimus-Eluting Stents Three Months After Implantation
Kenichi Fujii; Daizo Kawasaki; Hirokuni Akahori; Tsuyoshi Nakata; Masashi Fukunaga; Hisashi Sawada; Motomaru Masutani; Masaaki Lee-Kawabata; Takeshi Tsujino; Mitsumasa Ohyanagi; Tohru Masuyama
CIRCULATION, Nov. 2010 - Characteristics of Patients with Pulmonary Hypertension but without Cardiovascular Diseases: a Study with Echocardiography
Ayumi Nakaboh; Akiko Goda; Misato Otsuka; Mitsuru Masaki; Chikako Yoshida; Akiyo Eguchi; Shinichi Hirotani; Masaaki L. Kawabata; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Nov. 2010 - Intraleaflet Hemorrhage is Associated with Rapid Progression of Degenerative Aortic Valve Stenosis
Hirokuni Akahori; Takeshi Tsujino; Yoshiro Naito; Mika Matsumoto; Chikako Yoshida; Kana Wakabayashi; Masaaki L. Kawabata; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Masataka Mitsuno; Yuji Miyamoto; Tohru Masuyama
CIRCULATION, Nov. 2010 - Rho/Rho-kinase inhibitor and peroxisome proliferator-activated receptors agonists attenuated leptin induces IL-18 expression with heart failure via the endothelin-1 pathway in cardiomyocytes
T. Doi; T. Sakoda; T. Akagami; T. Naka; T. Tsujino; T. Masuyama; M. Ohyanagi
EUROPEAN HEART JOURNAL SUPPLEMENTS, Oct. 2010 - Increased interleukin-18 expression in nonrheumatic aortic valve stenosis
Yoshiro Naito; Takeshi Tsujino; Kana Wakabayashi; Mika Matsumoto; Mitsumasa Ohyanagi; Masataka Mitsuno; Yuji Miyamoto; Hiroyuki Hao; Seiichi Hirota; Haruki Okamura; Tohru Masuyama
INTERNATIONAL JOURNAL OF CARDIOLOGY, Oct. 2010 - Long-Term Administration of Atorvastatin Improves LV Diastolic Function in Diastolic Heart Failure Model of Dahl Salt-Sensitive Rats
Hirokuni Akahori; Takeshi Tsujino; Yoshiro Naito; Mika Matsumoto; Akiyo Eguchi; Naoko Sasaki; Masaaki Kawabata; Tohru Masuyama
JOURNAL OF CARDIAC FAILURE, Sep. 2010 - Addition of Statins Enhances Benefits of Cardiac Rehabilitation in Terms of Left Ventricular Diastolic Function
Chikako Yoshida; Masaaki Lee-Kawabata; Akiko Goda; Misato Otuska; Ayumi Nakaboh; Akiyo Eguchi; Hisashi Sawada; Shinichi Hirotani; Takeshi Tsujino; Tohru Masuyama
JOURNAL OF CARDIAC FAILURE, Sep. 2010 - Coronary Plaque Characteristics of Thin-cap Fibroatheroma: An Intravascular Ultrasound and Optical Coherence Tomography Study
Masashi Fukunaga; Kenichi Fujii; Motomaru Masutani; Daizo Kawasaki; Katsumi Oka; Hirokuni Akahori; Shohei Fujiwara; Takeshi Tsujino; Mitsumasa Ohyanagi; Tohru Masuyama
CIRCULATION, Nov. 2009 - Leptin induces interleukin-18 via endothelin-1-Rho/Rho-kinase-PPAR/NF-kB pathway in cardiomyocytes
T. Doi; T. Sakoda; T. Akagami; T. Naka; T. Tsujino; T. Masuyama; M. Ohyanagi
EUROPEAN HEART JOURNAL, Sep. 2009 - Effect of Beta-blokers on Glucose Tolerance and Exercise Intolerance in Patients With Chronic Heart Failure (Bisoprolol vs Carvedilol)
Toshio Naka; Takafumi Akagami; Tsuyoshi Sakoda; Takeshi Tsujino; Tohru Masuyama; Mitsumasa Ohyanagi
JOURNAL OF CARDIAC FAILURE, Sep. 2009 - Longitudinal Displacement of Mitral Annulus Shows Early Recovery Following Induction of Beta-Blockade In Patients with Chronic Heart Failure
Chikako Yoshida; Masaaki Lee-Kawabata; Takeshi Tsujino; Shinji Nakao; Akiko Goda; Akira Ezumi; Tohru Masuyama
CIRCULATION, Oct. 2008 - Change in Plasma Aldosterone Concentration is Important Determinant of Regression of LV Hypertrophy Following Anti-Hypertensive Medication
Chikako Yoshida; Takeshi Tsujino; Akiko Goda; Yoshiro Naito; Shinji Nakao; Masao Yuba; Misato Otsuka; Mika Matsumoto; Masaaki Lee-Kawabata; Akira Ezumi; Tohru Masuyama
CIRCULATION, Oct. 2008 - Myocardial Fibrosis and Diastolic Dysfunction Following Calcium-Channel Blockers or Angiotensin II Receptor Blockers in Hypertensive Patients
Chikako Yoshida; Takeshi Tsujino; Akiko Goda; Mika Matsumoto; Yoshiro Naito; Shinji Nakao; Akira Ezumi; Masaaki Lee-Kawabata; Tohru Masuyama
CIRCULATION, Oct. 2008 - Left Ventricular Torsion Reflects Degree of Myocardial Fibrosis in Hypertrophic Cardiomyopathy
Ayumi Nakaboh; Akiko Goda; Shinji Nakao; Katsumi Oka; Takeshi Tsujino; Masao Yuba; Misato Otsuka; Mika Matsumoto; Chikako Yoshida; Yoshiro Naito; Masaaki Lee-Kawabata; Tohru Masuyama
CIRCULATION, Oct. 2008 - The Usefulness of Serum Hepcidin Measurement in Chronic Heart Failure
Mika Matsumoto; Takeshi Tsujino; Masaaki Lee-Kawabata; Yoshim Naito; Akira Ezumi; Shinji Nakao; Akiko Goda; Chikako Yoshida; Kunihiro Akahori; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Naohisa Tomosugi; Tohru Masuyama
CIRCULATION, Oct. 2008 - High Serum Erythropoietin Level is Associated with Poor Prognosis in Heart Failure Patients with Systolic Dysfunction but not with Preserved Systolic Function
Mika Matsumoto; Takeshi Tsujino; Masaaki Lee-Kawabata; Yoshiro Naito; Akira Ezumi; Shinji Nakao; Akiko Goda; Chikako Yoshida; Kunihiro Akahori; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Tohru Masuyama
CIRCULATION, Oct. 2008 - Large temporal increase in serum adiponectin concentration in acute decompensation was associated with good prognosis in patients with heart failure
Mika Matsumoto; Takeshi Tsujino; Masaaki Kawabata; Yoshiro Naito; Akira Ezumi; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Tohru Masuyama
JOURNAL OF CARDIAC FAILURE, Sep. 2008 - Stalin therapy improve with exercise intolerance in patients with chronic heart failure?
Toshio Naka; Tsuyoshi Sakoda; Takeshi Tsujino; Tohru Masuyama; Mitsumasa Ohyanagi
JOURNAL OF CARDIAC FAILURE, Sep. 2008 - Multicenter study for testing long-term outcome of diuretic therapy in chronic heart failure: Is long-acting diuretics superior to short-acting diuretics?
Tohru Masuyama; Takeshi Tsujino
JOURNAL OF CARDIAC FAILURE, Sep. 2008 - The difference between systolic heart failure and diastolic heart failure: From the viewpoint of biomarkers
Takeshi Tsujino; Mika Matsumoto; Masaaki Lee-Kawabata; Tohru Masuyama
JOURNAL OF CARDIAC FAILURE, Sep. 2008 - Characteristics of circadian blood pressure variation in Otsuka Long-Evans Tokushima Fatty (OLETF) rat and Long-Evans Tokushima (LETO) rat
M. Matsumoto; T. Tsujino; Y. Naito; T. Sakoda; M. Ohyanagi; T. Masuyama
JOURNAL OF HYPERTENSION, Jun. 2008 - Dosing time of captopril is essential in inhibiting tissue angiotensin converting enzyme activity and improving survival rate of stroke-prone spontaneously hypertensive rats
T. Tsujino; M. Matsumoto; Y. Naito; T. Sakoda; M. Ohyanagi; T. Masuyama
JOURNAL OF HYPERTENSION, Jun. 2008 - Interleukin-18 (IL-18), endothelin-1 and aldosterone induce smooth muscle senescence via Rho-kinase- and PPAR-dependent pathways
T. Akagami; T. Sakoda; T. Doi; T. Naka; T. Tsujino; T. Masuyama; M. Ohyanagi
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Apr. 2008 - Dosing time of angiotensin converting enzyme inhibitor is important for protecting organ damage in hypertension
Takeshi Tsujino; Mika Matsumoto; Yoshiro Naito; Yoshida Chilkako; Kana Wakabayashi; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Tohru Masuyama
CIRCULATION, Oct. 2007 - Relation between left ventricular chamber stiffness constant and turnover of type I collagen in heart failure
Mika Matsumoto; Takeshi Tsujino; Yoshiro Naito; Masaaki Lee; Shinji Nakao; Akiko Goda; Chikako Yoshida; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Tohru Masuyama
CIRCULATION, Oct. 2007 - Angiotensin converting enzyme inhibitor is the only drug that slows the progression of aortic stenosis among first-line antithypertensive agents
Kana Wakabayashi; Tsujino Takeshi; Goda Akiko; Shinji Nakao; Naito Yoshiro; Misato Otsuka; Mika Matsumoto; Chikako Yoshida; Masaaki Lee; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Yasushi Sakata; Kazuhiro Yanamoto; Thoru Masuyama
CIRCULATION, Oct. 2007 - Aldosterone induced IL-18 expression through Endotheline-1 and Angiotensin II via Rho, Rho-kinase and PPAR in cardiomyocytes
T. Doi; T. Sakoda; T. Akagami; T. Naka; T. Tsujino; T. Masuyama; M. Ohyanagi
EUROPEAN HEART JOURNAL, Sep. 2007 - Hyperglycemia-induced cell growth and gene expression via serum response element through Pkc beta, Rhoa, and Rho-kinase in vascular smooth muscle cells
Kai Ishiko; Tsuyoshi Sakoda; Takahumi Akagami; Takashi Doi; Toshio Naka; Takeshi Tsujino; Tohru Masuyama; Mitsumasa Ohyanagi
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, Jun. 2007 - Hepatocyte growth factor generated in the distal segment of the occlusive lesions enhances the collateral development in peripheral artery disease
Daizo Kawasaki; Takeshi Tsujino; Kenichi Fujii; Motomaru Masutani; Masaaki Lee; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Tohru Masuyama
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Mar. 2007 - Organ protective effect of captopril is dependent on dosing time in stroke prone spontaneously hypertensive rats
Takeshi Tsujino; Mika Matsumoto; Satoshi Okuda; Yoshiro Naito; Miho Masai; Shinji Morimoto; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Tohru Masuyama
JOURNAL OF HYPERTENSION, Dec. 2006 - Inhibitory action of ppar agonists, pioglitazone and bezafibrate on aldosterone-induced interleukin-18 (IL-18) expression in cardiomyocytes.
Takashi Doi; Tsuyoshi Sakoda; Takafumi Akagami; Toshio Naka; Takeshi Tsujino; Tohru Masuyama; Mitsumasa Ohyanagi
JOURNAL OF HYPERTENSION, Dec. 2006 - Messenger RNA expression of many genes show altered circadian variations in aorta of spontaneously hypertensive rats
Satoshi Okuda; Takeshi Tsujino; Mika Matsumoto; Yoshiro Naito; Takahiro Okumura; Daizo Kawasaki; Tsuyoshi Sakoda; Mitsumasa Ohyanagi; Tohru Masuyama
JOURNAL OF HYPERTENSION, Dec. 2006 - Anemia as a factor that elevates plasma brain natriuretic peptide concentration in healthy subjects
Mika Matsumoto; Takeshi Tsujino; Masaaki Lee; Kazuhiro Yamamoto; Toshiaki Man; Tohru Masuyama
JOURNAL OF HYPERTENSION, Dec. 2006 - The impact of stent expansion on epicardial flow and myocardial perfusion after stent implantation in patients with ST-segment elevation myocardial infarction
Takafumi Akagami; Kenichi Fujii; Motomaru Masutani; Takahiro Okumura; Daizo Kawasaki; Takeshi Tsujino; Tsuyohi Sakoda; Tohru Masuyama; Mitsumasa Ohyanagi
AMERICAN JOURNAL OF CARDIOLOGY, Oct. 2006 - PPAR agonist, pioglitazone inhibits interleukin-18 (IL-18)-induced gene expression and apoptosis in cardiac myocytes
Takafumi Akagami; Tsuyoshi Sakoda; Takashi Doi; Toshio Naka; Takeshi Tsujino; Tohru Masuyama; Mitsumasa Ohyanagi
JOURNAL OF CARDIAC FAILURE, Oct. 2006 - The natural history of non-obstructive residual stent edge dissections detected by intravascular ultrasound after sirolimus-eluting stent implantation
Kenichi Fujii; Motomaru Masutani; Shinji Morimoto; Tsuyoshi Sakoda; Takeshi Tsujino; Tohru Masuyama; Mitsumasa Ohyanagi
AMERICAN JOURNAL OF CARDIOLOGY, Oct. 2006 - Progression of aortic stenosis is slowed by angiotensin-converting enzyme inhibition but not by angiotensin II type 1 receptor blockade
Kana Wakabayashi; Akiko Goda; Shinji Nakao; Misato Otsuka; Mika Matsumoto; Chikako Tsutsumi; Masaaki Lee; Takeshi Tsujino; Tohru Masuyama
CIRCULATION, Oct. 2006 - Left ventricular diastolic dysfunction in diabetic patients: Pathophysiology and therapeutic implications
Takeshi Tsujino; Daizo Kawasaki; Tohru Masuyama
American Journal of Cardiovascular Drugs, 2006 - Mechanical stretch induces interleukin-18 expression through angiotensin subtype 1 receptor, Rho/Rho-Kinase signal transduction pathway in cardiomyocytes
T Naka; T Sakoda; T Doi; T Tsujino; T Masuyama; M Ohyanagi
JOURNAL OF CARDIAC FAILURE, Dec. 2005 - Plasma interleukin-18 concentration: a novel marker of myocardial ischemia rather than necrosis in humans
D Kawasaki; T Tsujino; S Morimoto; M Masai; M Masutani; M Ohyanagi; S Kashiwamura; H Okamura; T Masuyama
CORONARY ARTERY DISEASE, Nov. 2005 - Long-term angiotensin II receptor blockade improves left ventricular diastolic filling in diabetic patients through modulation of collagen type 1 turnover and diastolic property
D Kawasaki; K Kosugi; H Waki; T Tsujino; T Masuyama
CIRCULATION, Oct. 2005 - Translocation of RhoA and Rho-kinase into nucleus is the novel mechanism of Interleukin (IL)-18-induced gene expression and apoptosis in cardiomyocytes
T. Sakoda; T. Naka; T. Doi; T. Tsujino; T. Masuyama; M. Ohyanagi
EUROPEAN HEART JOURNAL, Sep. 2005 - Role of activated renin-angiotensin system in myocardial fibrosis and left ventricular diastolic dysfunction in diabetic patients: Reversal by longterm angiotensin II blockade
D Kawasaki; K Kosugi; H Waki; K Yamamoto; T Tsujino; T Masuyama
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Feb. 2005 - Circadian expression of plasminogen activator inhibitor-1 in angiotensin II type 1a receptor knockout mice
T Tsujino; Y Naito; D Kawasaki; S Okuda; T Sakoda; Y Fujioka; T Sugaya; M Ohyanagi
CLINICAL AND EXPERIMENTAL HYPERTENSION, Feb. 2005 - Novel mechanism of the translocation of RhoA and Rho-kinase into nucleus is important for interieukin (IL)-18-induced gene expression and apoptosis in cardiac myocytes
T Sakoda; T Naka; T Tsujino; T Masuyama; M Ohyanagi
CIRCULATION, Oct. 2004 - Translocation Rho kinase from cytosol to nucleus interacted with p300 and subsequently upregulated c-fos, NF-kB, and b-MHC gene expression in cardiac myocytes
T Sakoda; T Naka; T Tsujino; M Ohyanagi
EUROPEAN HEART JOURNAL, Aug. 2004 - Ultrasound enhances retroviral-mediated gene transfer
T Naka; T Sakoda; Y Fujioka; T Tsujino; M Ohyanagi
MOLECULAR THERAPY, May 2004 - Circadian expression of plasminogen activator inhibitor-1 (PAI-1) in angiotensin II type1a receptor knockout mice
Y Naito; T Tsujino; S Okuda; D Kawasaki; T Sakoda; Y Fujioka; M Ohyanagi
JOURNAL OF HYPERTENSION, Feb. 2004 - Altered circadian gene expression of cardiac renin-angiotensin system in spontaneously hypertensive rats
T Tsujino; Y Naito; D Kawasaki; S Okuda; Y Fujinoka; T Sakoda
JOURNAL OF HYPERTENSION, Feb. 2004 - Urine 8-isoprostane is a useful marker for oxidative stress in hypertension
T Tsujino; T Okumura; Y Fujioka; M Kimura; D Kawasaki; Y Naito; S Morimoto; M Masai; T Sakoda; T Tsujino; M Ohyanagi
JOURNAL OF HYPERTENSION, Feb. 2004 - Circadian expression of plasminogen activator inhibitor-1 (PAI-1) and clock genes in heart and aorta of spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats
S Okuda; T Tsujino; Y Naito; D Kawasaki; T Okumura; S Morimoto; M Masai; T Sakoda; Y Fujioka; M Ohyanagi
JOURNAL OF HYPERTENSION, Feb. 2004 - Marked difference in diurnal variations of circulating angiotensin II between spontaneously hypertensive and Wistar-Kyoto rats
Y Naito; T Tsujino; S Okuda; D Kawasaki; T Naka; T Abe; T Sakoda; Y Fujioka; M Ohyanagi
JOURNAL OF HYPERTENSION, Feb. 2004 - p300 and serum response factor are involved in Rho kinase-mediated C-fos gene expression in cardiac myocytes
T Sakoda; T Naka; T Abe; Y Fujioka; T Tsujino; T Iso; Y Hamamori; M Ohyanagi
CIRCULATION, Oct. 2003 - Circadian expression of plasminogen activator inhibitor-1 (PAI-1) and clock genes in aorta of Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR)
Y Naito; T Tsujino; S Okuda; D Kawasaki; T Okumura; S Morimoto; M Asai; T Sakoda; Y Fujioka; M Ohyanagi
ATHEROSCLEROSIS SUPPLEMENTS, Sep. 2003 - Bezafibrate improves hypertension and insulin sensitivity in humans
Jong Il Kim; Takeshi Tsujino; Yoshio Fujioka; Komei Saito; Mitsuhiro Yokoyama
Hypertension Research, 01 Apr. 2003 - 103)感染性心内膜炎に合併した細菌性脳動脈瘤の一例(日本循環器学会 第92回近畿地方会)
土居 隆; 辻野 健; 大柳 光正; 岩崎 忠昭; 横田 正幸; 林 宏; 有田 憲生
Circulation journal : official journal of the Japanese Circulation Society, 20 Apr. 2002 - NUCLEAR FACTOR-BINDING TO REGIONS OF THE ANGIOTENSIN-II AT1A RECEPTOR (AT1A-R) GENE THAT MEDIATE TRANSCRIPTIONAL ACTIVATION IN RAT VASCULAR SMOOTH-MUSCLE CELLS (VSMC)
T TSUJINO; RW ALEXANDER; TJ MURPHY
FASEB JOURNAL, Mar. 1995
Lectures, oral presentations, etc.
- Ultrasound increases retrovirus-mediated gene transfer to endothelial cells and vascular smooth muscle cells
T Naka; T Sakoda; T Abe; Y Fujioka; T Tsujino; M Ohyanagi
ATHEROSCLEROSIS SUPPLEMENTS, Sep. 2003 - Circadian expression of plasminogen activator inhibitor-1 mRNA in rat heart: Effects of beta-blocker and angiotensin AT(1) receptor blocker
Y Naito; T Tsujino; D Kawasaki; S Tsuboi; T Okumura; S Morimoto; M Masai; Y Fujioka; T Iwasaki
JOURNAL OF HYPERTENSION, Jun. 2002 - Decreased ornithine decarboxylase activity in the kidney of Dahl salt-sensitive rat
T Hayashi; T Tsujino; N Emoto; Y Yano; S Otani; M Yokoyama
JOURNAL OF HYPERTENSION, Jun. 2002 - Taurine prevents homocyst(e)ine induced down-regulation of extracellular superoxide dismutase expression in rat vascular smooth muscle cells
H Nonaka; Y Watari; S Iwata; H Harada; T Hayashi; T Tsujino
CIRCULATION, Nov. 1999 - Decreased arginase activity in the kidney of Dahl salt sensitive rat
S Iwata; H Harada; H Nonaka; K Kitazaki; Y Watari; T Tsujino
CIRCULATION, Oct. 1998 - ROLE OF CHLORIDE AND SODIUM IN DOCA-SALT HYPERTENSIVE RATS
Y KUBOTA; J KAWAHARA; ST HSIEH; T TSUJINO; K HATTORI; H SANO
CIRCULATION, Oct. 1990 - ORAL MAGNESIUM SUPPLEMENTATION PREVENTS ALCOHOL-INDUCED HYPERTENSION IN RATS
ST HSIEH; H SANO; Y KUBOTA; T TSUJINO; J KAWAHARA; K HATTORI
CIRCULATION, Oct. 1990
Research Themes
- Does liver fibrosis aggravate heart failure?
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2023 - 31 Mar. 2026 - Examination of the effect that sleep education in the pregnancy period for blood pressure prevention for pregnancy hypertension syndrome gives to blood pressure
Grant-in-Aid for Scientific Research (C)
Hyogo University of Health Sciences
01 Apr. 2015 - 31 Mar. 2019 - The role of inflammation and oxydative stress in the development of anemia in chronic heart failure
Grant-in-Aid for Scientific Research (C)
Hyogo University of Health Sciences
01 Apr. 2015 - 31 Mar. 2018 - Investigation of anemia and iron metabolism in chronic heart failure
Grant-in-Aid for Scientific Research (C)
Hyogo University of Health Sciences
01 Apr. 2012 - 31 Mar. 2015 - Mechanisms of abnormal iron metabolism in metabolic syndrome and its implications for new therapeutic strategies
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
2009 - 2011 - 心不全における貧血の発症機序
2008 - Ultrasound imaging for tissue characterization to assess cardiovascular involvement in diabetes
Grant-in-Aid for Scientific Research (B)
Hyogo Medical University
2005 - 2006 - レニン・アンジオテンシン系抑制薬の時間薬理学
2005 - Ultrasound imaging of extracellular matrix remodeling for assessing congestive heart failure
Grant-in-Aid for Scientific Research (B)
2003 - 2004 - 自然発症高血圧ラットにおけるレニン・アンジオテンシン系日内変動の異常
2000 - Abnormal circadian variation in renin-angioteusin system in SHR
2000 - 大動脈弁狭窄症の進行促進因子について
- The role of homocysteine-induced ER stress in atherosclerosis
- The role of IL-18 in congestive heart failure
- The role of arginase in salt-sensitive hypertension
