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昭和57年大阪大学医学部卒業。研修後循環器内科医として診療に従事。昭和62年より大阪大学医学部生化学講座にて生化学の研究・教育に従事。平成元年に大阪大学医学部助手（生化学講座）。同助教授を経て平成11年兵庫医科大学生化学講座主任教授。その後教務部長、医学教育センター長、医療人育成研修センター長、臨床教育統括センター長、 副学長（教育担当）等を併任。2023年3月で生化学講座教授を定年退職し現在は兵庫医科大学学長。
Last Updated :2024/12/19
Researcher Information
Field Of Study
Career
- Apr. 2023 - Present
Hyogo Medical University, President - Oct. 1999 - Mar. 2023
Hyogo Medical University, Faculty of Medicine, Department of Biochemistry, Professor, Chairman, MD, PhD - 1998 - 1999
Osaka University - 1998 - 1999
Osaka University Medical School, Associate - 1999
大阪大学大学院 助教授 - 1999
- Hyogo College of Medicine, Professor - 1999
Osaka University Graduate School of Medicine - 1992 - 1998
Osaka University - 1992 - 1998
Osaka University Medical School, Assistant - 1989 - 1992
Osaka University - 1989 - 1992
Osaka University Medical School, Research - Associate Professor
- Professor
- Associate
Educational Background
Research activity information
Paper
- The Ile35 Residue of the ALS-Associated Mutant SOD1 Plays a Crucial Role in the Intracellular Aggregation of the Molecule.
Yoshiyuki Asai; Kyoka Yano; Tomoyuki Higashino; Daisaku Yoshihara; Haruhiko Sakiyama; Hironobu Eguchi; Kazuaki Fukushima; Keiichiro Suzuki; Noriko Fujiwara
Molecular neurobiology, Jul. 2024 - 家族性ALSを引き起こす変異SOD1の凝集体形成に寄与するIle35
矢埜 杏果; 浅井 新喜; 東野 智行; 吉原 大作; 江口 裕伸; 崎山 晴彦; 鈴木 敬一郎; 藤原 範子
日本生化学会大会プログラム・講演要旨集, Oct. 2023 - HepG2細胞におけるc-Metのリン酸化に対するNOの影響
江口 裕伸; 浜崎 重彰; 崎山 晴彦; 吉原 大作; 藤原 範子; 塚本 蔵; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Oct. 2023 - Iron deficiency aggravates DMNQ-induced cytotoxicity via redox cycling in kidney-derived cells.
Daisaku Yoshihara; Noriko Fujiwara; Hironobu Eguchi; Haruhiko Sakiyama; Keiichiro Suzuki
Free radical research, Dec. 2022 - ChREBP deficiency prevents high sucrose diet-induced obesity through reducing sucrase expression.
Haruhiko Sakiyama; Lan Li; Minako Inoue; Hironobu Eguchi; Daisaku Yoshihara; Noriko Fujiwara; Keiichiro Suzuki
Journal of clinical biochemistry and nutrition, Nov. 2022 - A lack of ChREBP inhibits mitochondrial cristae formation in brown adipose tissue.
Haruhiko Sakiyama; Lan Li; Sachi Kuwahara-Otani; Tsutomu Nakagawa; Hironobu Eguchi; Daisaku Yoshihara; Masakazu Shinohara; Noriko Fujiwara; Keiichiro Suzuki
Molecular and cellular biochemistry, Oct. 2021 - Activation of the mitogen-activated protein kinase ERK1/2 signaling pathway suppresses the expression of ChREBPα and β in HepG2 cells.
Lan Li; Haruhiko Sakiyama; Hironobu Eguchi; Daisaku Yoshihara; Noriko Fujiwara; Keiichiro Suzuki
FEBS open bio, Jul. 2021 - Glycation in Disease
Motoko Takahashi; Keiichiro Suzuki; Yoshitaka Ikeda; Naoyuki Taniguchi
Comprehensive Glycoscience: Second Edition, Jun. 2021 - Introduction of team-based learning improves understanding of glucose metabolism in biochemistry among undergraduate students.
Hironobu Eguchi; Haruhiko Sakiyama; Hitoshi Naruse; Daisaku Yoshihara; Noriko Fujiwara; Keiichiro Suzuki
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, May 2021 - Cu/Zn-スーパーオキシドディスムターゼの凝集および線維ゲル形成におけるpH依存性
藤原 範子; 我妻 美千留; 麻見 安雄; 吉原 大作; 江口 裕伸; 崎山 晴彦; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2019 - Basic skills examination in a biochemical practical training program for undergraduate students.
Sakiyama H; Eguchi H; Yoshihara D; Ookawara T; Naruse H; Fujiwara N; Suzuki K
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, May 2019, [Reviewed] - Cu/Zn-superoxide dismutase forms fibrillar hydrogels in a pH-dependent manner via a water-rich extended intermediate state.
Fujiwara N; Wagatsuma M; Oba N; Yoshihara D; Tokuda E; Sakiyama H; Eguchi H; Ichihashi M; Furukawa Y; Inoue T; Suzuki K
PloS one, 2018, [Reviewed] - Cu,Zn-SOD deficiency induces the accumulation of hepatic collagen.
Sakiyama H; Fujiwara N; Yoneoka Y; Yoshihara D; Eguchi H; Suzuki K
Free radical research, Jun. 2016, [Reviewed] - Glyco-redox, a link between oxidative stress and changes of glycans: Lessons from research on glutathione, reactive oxygen and nitrogen species to glycobiology
Naoyuki Taniguchi; Yasuhiko Kizuka; Shinji Takamatsu; Eiji Miyoshi; Congxiao Gao; Keiichiro Suzuki; Shinobu Kitazume; Kazuaki Ohtsubo
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Apr. 2016, [Reviewed] - The absence of the SOD1 gene causes abnormal monoaminergic neurotransmission and motivational impairment-like behavior in mice.
Yoshihara D; Fujiwara N; Kitanaka N; Kitanaka J; Sakiyama H; Eguchi H; Takemura M; Suzuki K
Free radical research, 2016, [Reviewed] - Impact of early interventions by a cardiac rehabilitation team on the social rehabilitation of patients resuscitated from cardiogenic out-of-hospital cardiopulmonary arrest.
Keiko Takahashi; Naoki Sasanuma; Yusuke Itani; Takashi Tanaka; Kazuhisa Domen; Tohru Masuyama; Mitsumasa Ohyanagi; Keiichiro Suzuki
Internal medicine (Tokyo, Japan), 2015 - 溶液酸素NMRによる酸化修飾タンパク質の新規検出方法
藤原 範子; 花島 慎弥; 山口 芳樹; 鄭 国慶; 鳥越 秀峰; 谷口 直之; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2013, [Reviewed] - A solution 17O-NMR approach for observing an oxidized cysteine residue in Cu,Zn-superoxide dismutase.
Hanashima S; Fujiwara N; Matsumoto K; Iwasaki N; Zheng GQ; Torigoe H; Suzuki K; Taniguchi N; Yamaguchi Y
Chemical communications (Cambridge, England), Feb. 2013, [Reviewed] - Cu/Zn-スーパーオキシドジスムターゼのループVI構造は2種類のタイプに分類される
藤原 範子; 伊原 健太郎; 山口 芳樹; 鳥越 秀峰; 若槻 壮市; 谷口 直之; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Dec. 2012, [Reviewed] - Structural switching of Cu,Zn-superoxide dismutases at loop VI: insights from the crystal structure of 2-mercaptoethanol-modified enzyme.
Ihara K; Fujiwara N; Yamaguchi Y; Torigoe H; Wakatsuki S; Taniguchi N; Suzuki K
Bioscience reports, Dec. 2012, [Reviewed] - Alterations in renal iron metabolism caused by a copper/zinc-superoxide dismutase deficiency.
Yoshihara D; Fujiwara N; Kato S; Sakiyama H; Eguchi H; Suzuki K
Free radical research, Jun. 2012, [Reviewed] - ヒトSOD1ダイマーのループVI構造は非対称である
藤原 範子; 伊原 健太郎; 鳥越 秀峰; 山口 芳樹; 若槻 壮市; 谷口 直之; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2011, [Reviewed] - Erratum to: N-Glycosylation profiling of recombinant mouse extracellular superoxide dismutase produced in Chinese hamster ovary cells.
Hiroaki Korekane; Atsuko Korekane; Yoshiki Yamaguchi; Masaki Kato; Yasuhide Miyamoto; Akio Matsumoto; Tomoko Hasegawa; Keiichiro Suzuki; Naoyuki Taniguchi; Tomomi Ookawara
Glycoconjugate journal, Aug. 2011, [Reviewed] - N-Glycosylation profiling of recombinant mouse extracellular superoxide dismutase produced in Chinese hamster ovary cells
Hiroaki Korekane; Atsuko Korekane; Yoshiki Yamaguchi; Masaki Kato; Yasuhide Miyamoto; Akio Matsumoto; Tomoko Hasegawa; Keiichiro Suzuki; Naoyuki Taniguchi; Tomomi Ookawara
GLYCOCONJUGATE JOURNAL, May 2011, [Reviewed] - Hydrogen peroxide enhances LPS-induced nitric oxide production via the expression of interferon beta in BV-2 microglial cells.
Eguchi H; Fujiwara N; Sakiyama H; Yoshihara D; Suzuki K
Neuroscience letters, Apr. 2011, [Reviewed] - 2-メルカプトエタノール修飾型Cu,Zn-SODの構造解析と安定性について
藤原 範子; 伊原 健太郎; 鳥越 秀峰; 小笹 哲夫; 金田 薫; 佐々木 澄美; 山口 芳樹; 若槻 壮市; 谷口 直之; 鈴木 敬一郎
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2010, [Reviewed] - The role of O-linked GlcNAc modification on the glucose response of ChREBP.
Sakiyama H; Fujiwara N; Noguchi T; Eguchi H; Yoshihara D; Uyeda K; Suzuki K
Biochemical and biophysical research communications, Nov. 2010, [Reviewed] - Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy.
Yokoe S; Asahi M; Takeda T; Otsu K; Taniguchi N; Miyoshi E; Suzuki K
Glycobiology, Oct. 2010, [Reviewed] - Antioxidants: Benefits and risks for long-term health
Daisaku Yoshihara; Noriko Fujiwara; Keiichiro Suzuki
MATURITAS, Oct. 2010, [Reviewed] - Induction of protective immunity by vaccination with wild-type apo superoxide dismutase 1 in mutant SOD1 transgenic mice.
Takeuchi S; Fujiwara N; Ido A; Oono M; Takeuchi Y; Tateno M; Suzuki K; Takahashi R; Tooyama I; Taniguchi N; Julien JP; Urushitani M
Journal of neuropathology and experimental neurology, Oct. 2010, [Reviewed] - 抗酸化能を獲得した2-メルカプトエタノール修飾型Cu,Zn-SODの構造解析
藤原 範子; 伊原 健太郎; 若槻 壮市; 谷口 直之; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2009, [Reviewed] - Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice.
Yoshihara D; Fujiwara N; Ookawara T; Kato S; Sakiyama H; Yokoe S; Eguchi H; Suzuki K
Free radical biology & medicine, Sep. 2009, [Reviewed] - O-GlcNacylation of phospholamban induces cardiac dysfunction
Michio Asahi; Shunichi Yokoe; Keiichiro Suzuki; Naoyuki Taniguchi; Eiji Miyoshi
FASEB JOURNAL, Apr. 2008 - Acute exercise increases expression of extracellular superoxide dismutase in skeletal muscle and the aorta
Yoshiaki Hitomi; Sumiko Watanabe; Takako Kizaki; Takuya Sakurai; Tohru Takemasa; Shukoh Haga; Tomomi Ookawara; Keiichiro Suzuki; Hideki Ohno
Redox Report, 2008, [Reviewed] - Neurochemical characterization of Long-Evans Cinnamon (LEC) rats, an animal model of Wilson's disease
Kitanaka Nobue; Kitanaka Junichi; Fujiwara Noriko; Yoshihara Daisaku; Tatsuta Tomohiro; Ookawara Tomomi; Iso Hiroyuki; Morita Yoshio; Suzuki Keiichiro; Takemura Motohiko
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2008, [Reviewed] - Oxidative modification to cysteine sulfonic acid of Cys(111) in human copper-zinc superoxide dismutase
Noriko Fujiwara; Miyako Nakano; Shinsuke Kato; Daisaku Yoshihara; Tomomi Ookawara; Hironobu Eguchi; Naoyuki Taniguchi; Keiichiro Suzuki
JOURNAL OF BIOLOGICAL CHEMISTRY, Dec. 2007 - Transcription regulation of gene expression in rat brown adipose tissue in response to unloading or 2G loading during growing period
S. Watanabe; Y. Hitomi; F. Kawano; Y. Ohira; T. Kizaki; N. Nakano; T. Sakurai; T. Izawa; K. Suzuki; M. Sudoh; R. R. Roy; H. Ohno
ACTA ASTRONAUTICA, May 2007, [Reviewed] - Glycation and Disease
M. Takahashi; K. Suzuki; Y. Ikeda; N. Taniguchi
Comprehensive Glycoscience: From Chemistry to Systems Biology, Jan. 2007, [Reviewed] - Inhibition of gene expression of heparin-binding epidermal growth factor-like growth factor by extracellular superoxide dismutase in rat aortic smooth muscle cells.
Nishimura M; Ookawara T; Eguchi H; Fujiwara N; Yoshihara D; Yasuda J; Mimura O; Suzuki K
Free radical research, Jun. 2006, [Reviewed] - Reactive oxygen species modify oligosaccharides of glycoproteins in vivo: a study of a spontaneous acute hepatitis model rat (LEC rat).
Yasuda J; Eguchi H; Fujiwara N; Ookawara T; Kojima S; Yamaguchi Y; Nishimura M; Fujimoto J; Suzuki K
Biochemical and biophysical research communications, Mar. 2006, [Reviewed] - Identification of oxidized Cys111 in human Cu/Zn-superoxide dismutase
Noriko Fujiwara; Miyako Nakano; Tomomi Ookawara; Hironobu Eguchi; Daisaku Yoshihara; Naoyuki Taniguchi; Keiichiro Suzuki
FREE RADICAL BIOLOGY AND MEDICINE, 2006 - Effect of copper metabolism on neurological function in Wistar and Wilson's disease model rats.
N. Fujiwara; H. Iso; N. Kitanaka; J. Kitanaka; H. Eguchi; T. Ookawara; K. Ozawa; S. Shimoda; D. Yoshihara; M. Takemura; K. Suzuki
Biochem. Biophyis. Res. Commun., 2006 - Tumor necrosis factor-alpha-induced iron sequestration and oxidative stress in human endothelial cells
M Nanami; T Ookawara; Y Otaki; K Ito; R Moriguchi; K Miyagawa; Y Hasuike; M Izumi; H Eguchi; K Suzuki; T Nakanishi
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, Dec. 2005 - Dysregulation of TGF-beta 1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice
XC Wang; S Inoue; JG Gu; E Miyoshi; K Noda; WZ Li; Y Mizuno-Horikawa; M Nakano; M Asahi; M Takahashi; N Uozumi; S Ihara; SH Lee; Y Ikeda; Y Yamaguchi; Y Aze; Y Tomiyama; J Fujii; K Suzuki; A Kondo; SD Shapiro; C Lopez-Otin; T Kuwaki; M Okabe; K Honke; N Taniguchi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Nov. 2005 - Modification of oligosaccharides by reactive oxygen species decreases sialyl Lewis x-mediated cell adhesion
H Eguchi; Y Ikeda; T Ookawara; S Koyota; N Fujiwara; K Honke; PG Wang; N Taniguchi; K Suzuki
GLYCOBIOLOGY, Nov. 2005 - Clostridium botulinum type A progenitor toxin binds to Intestine-407 cells via N-acetyllactosamine moiety.
Kojima S; Eguchi H; Ookawara T; Fujiwara N; Yasuda J; Nakagawa K; Yamamura T; Suzuki K
Biochemical and biophysical research communications, Jun. 2005, [Reviewed] - Control of NO Production
Naoyuki Taniguchi; Noriko Fujiwara; Keiichiro Suzuki
Nitric Oxide Donors: For Pharmaceutical and Biological Applications, May 2005, [Reviewed] - Induction of thioredoxin reductase as an adaptive response to acrolein in human umbilical vein endothelial cells.
Park YS; Misonou Y; Fujiwara N; Takahashi M; Miyamoto Y; Koh YH; Suzuki K; Taniguchi N
Biochemical and biophysical research communications, Feb. 2005, [Reviewed] - Different immunoreactivity against monoclonal antibodies between wild-type and mutant copper/zinc superoxide dismutase linked to amyotrophic lateral sclerosis
N Fujiwara; Y Miyamoto; K Ogasahara; M Takahashi; T Ikegami; R Takamiya; K Suzuki; N Taniguchi
JOURNAL OF BIOLOGICAL CHEMISTRY, Feb. 2005 - Overexpression of mutated Cu,Zn-SOD in neuroblastoma cells results in cytoskeletal change
R Takamiya; M Takahashi; YS Park; Y Tawara; N Fujiwara; Y Miyamoto; JG Gu; K Suzuki; N Taniguchi
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, Feb. 2005 - ウィルソン病モデルラットでは運動機能の増大とプレパルス抑制の低下が認められる(Increased motor function and reduced prepulse inhibition in Wilson disease model rats)
藤原 範子; 磯 博行; 北中 順惠; 北中 純一; 尾澤 敬一郎; 下田 重朗; 江口 裕伸; 大河原 知水; 竹村 基彦; 鈴木 敬一郎
神経化学, Aug. 2004, [Reviewed] - Extracellular superoxide dismutaze and lifestyle related diseases.
Ohno H; Ookawara T; Kizaki T; Hitomi Y; Oh-ishi S; Saitoh D; Kimoto K; Itoh C; Izawa T; Haga S; Suzuki K; Radak Z
Current Topics in Pharmacology, 2004, [Reviewed] - Down-regulation of β2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation.
Itoh CE; Kizaki T; Hitomi Y; Hanawa T; Kamiya S; Ookawara T; Suzuki K; Izawa T; Saitoh D; Haga S; Ohno H
Biochemical and Biophysical Research Communications, 2004, [Reviewed] - Relationship between elevated FX expression and increased production of GDP-L-fucose, a common donor substrate for fucosylation in human hepatocellular carcinoma and hepatoma cell lines
K Noda; E Miyoshi; JG Gu; CX Gao; S Nakahara; T Kitada; K Honke; K Suzuki; H Yoshihara; K Yoshikawa; K Kawano; M Tonetti; A Kasahara; M Hori; N Hayashi; N Taniguchi
CANCER RESEARCH, Oct. 2003, [Reviewed] - Angiotensin II type 1 receptor blockade prevents diastolic heart failure through modulation of Ca2+ regulatory proteins and extracellular matrix
Y Sakata; K Yamamoto; T Mano; N Nishikawa; J Yoshida; H Nakayama; K Otsu; K Suzuki; M Tada; M Hori; T Miwa; T Masuyama
JOURNAL OF HYPERTENSION, Sep. 2003 - Effects of endurance training on three superoxide dismutase isoenzymes in human plasma
T Ookawara; S Haga; S Ha; S Oh-Ishi; K Toshinai; T Kizaki; LL Ji; K Suzuki; H Ohno
FREE RADICAL RESEARCH, Jul. 2003 - 銅イオンのヒストンH4のアセチル化に対する影響
宮本 泰豪; 康 九紅; 藤原 範子; 三善 英知; 本家 孝一; 鈴木 敬一郎; 谷口 直之
生化学, Aug. 2002, [Reviewed] - Inhibitory effects of agarose gel and LB medium on DNA sequencing
Y Yamaguchi; S Nimbari; T Ookawara; K Oishi; H Eguchi; K Suzuki
BIOTECHNIQUES, Aug. 2002, [Reviewed] - Nuclear translocation of extracellular superoxide dismutase.
Ookawara T; Kizaki T; Takayama E; Imazeki N; Matsubara O; Ikeda Y; Suzuki K; Li JL; Tadakuma T; Taniguchi N; Ohno H
Biochemical and biophysical research communications, Aug. 2002, [Reviewed] - [Effects of agarose and LB medium on dye-terminator DNA sequencing].
Yamaguchi Y; Nimbari S; Obata H; Ookawara T; Eguchi H; Kurotsu T; Suzuki K
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, Jul. 2002, [Reviewed] - Myocardial stiffness is determined by ventricular fibrosis, but not by compensatory or excessive hypertrophy in hypertensive heart
K Yamamoto; T Masuyama; Y Sakata; N Nishikawa; T Mano; J Yoshida; T Miwa; M Sugawara; Y Yamaguchi; T Ookawara; K Suzuki; M Hori
CARDIOVASCULAR RESEARCH, Jul. 2002 - Thioredoxin reductase gene expression by reactive nitrogen species in human umbilical vein endothelial cells
YS Park; N Fujiwara; YH Koh; Y Miyamoto; K Suzuki; N Taniguchi
FASEB JOURNAL, Mar. 2002 - Post-ischemic transcriptional and translational responses of EC-SOD in mouse brain and serum
S Fukui; T Ookawara; H Nawashiro; K Suzuki; K Shima
FREE RADICAL BIOLOGY AND MEDICINE, Feb. 2002 - Transcription regulation of gene expression in human skeletal muscle in response to endurance training.
Tomomi Ookawara; Kenji Suzuk; Shukoh Haga; Sung Ha; Kil-Sang Chung; Koji Toshinai; Takafumi Hamaoka; Toshihito Katsumura; Tohru Takemasa; Masao Mizuno; Yoshiaki Hitomi; Takako Kizaki; Keiichiro Suzuki; Hideki Ohno
Research communications in molecular pathology and pharmacology, 2002 - Dysfunction of antioxidative enzymes and redox regulation: Protective mechanisms against nitrosative stress and glycoxidative stress
YS Park; YH Koh; Y Miyamoto; K Suzuki; N Taniguchi
XI BIENNIAL MEETING OF THE SOCIETY FOR FREE RADICAL RESEARCH INTERNATIONAL, 2002, [Reviewed] - Inactivation of thioredoxin reductase by acrolein
YS Park; N Fujiwara; YH Koh; M Takahashi; Y Miyamoto; K Suzuki; N Taniguchi
MAILLARD REACTION IN FOOD CHEMISTRY AND MEDICAL SCIENCE: UPDATE FOR THE POSTGENOMIC ERA, 2002, [Reviewed] - Dysfunction of antioxidative enzymes and redox regulation under nitrosative stress and glycoxidative stress
Y Miyamoto; YH Koh; WY Che; YS Park; N Fujiwara; T Ookawara; K Suzuki; N Taniguchi
MAILLARD REACTION IN FOOD CHEMISTRY AND MEDICAL SCIENCE: UPDATE FOR THE POSTGENOMIC ERA, 2002, [Reviewed] - Stress- and aging-associated modulation of macrophage functions
Takako Kizaki; Kenji Suzuki; Tomomi Ookawara; Tetsuya Izawa; Daizoh Saitoh; Shuji Oh-Ishi; Keiichiro Suzuki; Shukoh Haga; Hideki Ohno
Environmental Health and Preventive Medicine, 2002 - Negative regulation of LPS-stimulated expression of inducible nitric oxide synthase by AP-1 in macrophage cell line J774A.1
T Kizaki; K Suzuki; Y Hitomi; K Iwabuchi; K Onoe; S Haga; H Ishida; T Ookawara; K Suzuki; H Ohno
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Dec. 2001 - ヒトα1,6フコース転移酵素のSplicing Variant遺伝子
山口 幸洋; 井原 秀之; 三善 英知; 池田 義孝; 大河原 知水; 谷口 直之; 鈴木 敬一郎
生化学, Nov. 2001 - Human alpha 1,6-fucosyltransferase gene is transcribed from multiple promoters.
Y Yamaguchi; Y Ikeda; H Ihara; J Yasuda; K Okuto; T Ookawara; N Taniguchi; K Suzuki
GLYCOBIOLOGY, Oct. 2001 - ヒトα1,6-フコース転移酵素の多重プロモーターによる各種腫瘍細胞での発現制御
山口 幸洋; 井原 秀之; 池田 義孝; 大河原 知水; 遠藤 猛; 畑中 豊; 黒津 敏嗣; 藤井 順逸; 谷口 直之; 鈴木 敬一郎
生化学, Aug. 2001 - 活性酸素の新しい生理的意義 細胞内小器官の機能制御 細胞外型スーパーオキシドジスムターゼの核移行とその意義
大河原 知水; 山口 幸洋; 高山 英次; 木崎 節子; 池田 義孝; 鈴木 敬一郎; 谷口 直之; 大野 秀樹
生化学, Aug. 2001 - Activation and apoptosis of murine peritoneal macrophages by acute cold stress (vol 283, pg 700, 2001)
T Kizaki; K Suzuki; Y Hitomi; K Iwabuchi; K Onoe; H Ishida; T Izawa; LL Ji; H Ohno
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jul. 2001 - 細胞外型スーパーオキシドジスムターゼの核移行性
大河原 知水; 山口 幸洋; 高山 英次; 木崎 節子; 池田 義孝; 大野 秀樹; 谷口 直之; 鈴木 敬一郎
生化学, Apr. 2001 - Inactivation of glutathione peroxidase by nitric oxide leads to the accumulation of H2O2 and the induction of HB-EGF via c-Jun NH2-terminal kinase in rat aortic smooth muscle cells
YH Koh; K Suzuki; WY Che; YS Park; Y Miyamoto; S Higashiyama; N Taniguchi
FASEB JOURNAL, Apr. 2001 - Expression of Cu,Zn-SOD, Mn-SOD and GST-pi in oral cancer treated with preoperative radiation therapy
N Terakado; S Shintani; Y Nakahara; M Mihara; K Tomizawa; K Suzuki; N Taniguchi; T Matsumura
ONCOLOGY REPORTS, Sep. 2000 - ヒトα1,6フコース転移酵素のsplicing variant遺伝子の組織特異性についての検討
山口 幸洋; 井原 秀之; 池田 義孝; 奥田 啓二; 大河原 知水; 谷口 直之; 鈴木 敬一郎
生化学, Aug. 2000 - A potent inhibitor of inducible nitric oxide synthase, ONO-1714, a cyclic amidine derivative
M Naka; T Nanbu; K Kobayashi; Y Kamanaka; M Komeno; R Yanase; T Fukutomi; S Fujimura; HG Seo; N Fujiwara; S Ohuchida; K Suzuki; K Kondo; N Taniguchi
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2000 - Inhibition of c-jun expression induces antioxidant enzymes under serum deprivation
YH Kim; M Takahashi; N Noguchi; E Suzuki; K Suzuki; N Taniguchi; E Niki
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Feb. 2000 - Serum extracellular superoxide dismutase in pediatric patients with various diseases as judged by an ELISA
T Ookawara; N Matsuura; T Oh-ishi; M Okazaki; T Kizaki; K Suzuki; Y Hitomi; K Suzuki; H Ohno
RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY, 2000 - Extracellular superoxide dismutase in tissues from obese (ob/ob) mice
C Nakao; T Ookawara; Y Sato; T Kizaki; N Imazeki; O Matsubara; S Haga; K Suzuki; N Taniguchi; H Ohno
FREE RADICAL RESEARCH, 2000 - Aldehyde reductase gene expression by lipid peroxidation end products, MDA and HNE
YH Koh; YS Park; M Takahashi; K Suzuki; N Taniguchi
FREE RADICAL RESEARCH, 2000 - Antioxidant binding of caeruloplasmin to myeloperoxidase: Myeloperoxidase is inhibited, but oxidase, peroxidase and immunoreactive properties of caeruloplasmin remain intact
YS Park; K Suzuki; S Mumby; N Taniguchi; JMC Gutteridge
FREE RADICAL RESEARCH, 2000 - The contribution of fructose and nitric oxide to oxidative stress in hamster islet tumor (HIT) cells through the inactivation of glutathione peroxidase
K Suzuki; KN Islam; H Kaneto; T Ookawara; N Taniguchi
ELECTROPHORESIS, Jan. 2000 - Glutathione peroxidase-like activity of caeruloplasmin as an important lung antioxidant
YS Park; K Suzuki; N Taniguchi; JMC Gutteridge
FEBS LETTERS, Sep. 1999 - 肝癌組織におけるα1-6 Fucosyltransferaseとフコシル化糖蛋白の発現についての検討
野田 勝久; 三善 英知; 江國 敦子; 池田 義孝; 鈴木 敬一郎; 佐々木 裕; 堀 正二; 松浦 成昭; 林 紀夫; 谷口 直之
日本癌学会総会記事, Aug. 1999 - 細胞外型スーパーオキシドジスムターゼのヘパリン結合ドメインは核移行シグナルとして機能する
大河原 知水; 木崎 節子; 大石 修司; 高山 英次; 今関 信夫; 松原 修; 芳賀 脩光; 池田 義孝; 鈴木 敬一郎; 藤井 順逸; 谷口 直之; 大野 秀樹
生化学, Aug. 1999 - The requirement of both intracellular reactive oxygen species and intracellular calcium elevation for the induction of heparin-binding EGF-like growth factor in vascular endothelial cells and smooth muscle cells.
Kayanoki Y; Higashiyama S; Suzuki K; Asahi M; Kawata S; Matsuzawa Y; Taniguchi N
Biochemical and biophysical research communications, May 1999, [Reviewed] - Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis: Possible implication for involvement of hydroxyl radicals
K Suzuki; H Eguchi; YH Koh; YS Park; N Taniguchi
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 1999 - The cytotoxicity of methylglyoxal and 3-deoxyglucosone is decreased in the aldehyde reductase gene-transfected cells
K Suzuki; YH Koh; N Taniguchi
ENZYMOLOGY AND MOLECULAR BIOLOGY OF CARBONYL METABOLISM 7, 1999, [Reviewed] - Nuclear targeting of extracellular superoxide dismutase
H Ohno; T Ookawara; T Kizaki; E Takayama; N Imazeki; O Matsubara; T Kondo; S Haga; K Suzuki; K Suzuki; N Taniguchi
FREE RADICAL BIOLOGY AND MEDICINE, 1999 - Hydroxyl radicals accelerates the cell adhesion of endothelium without de novo protein synthesis
K Suzuki; H Eguchi; YH Koh; S Park; T Ookawara; N Taniguchi
FREE RADICAL BIOLOGY AND MEDICINE, 1999 - Effects of acute cold stress on mRNA expression and immunoreactivity of three superoxide dismutase isoenzymes in genetically obese mice
C Nakao; T Ookawara; T Kizaki; K Suzuki; S Haga; Y Sato; H Ohno
RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY, 1999 - Angiotensin II type 1 receptor-mediated peroxide production in human macrophages
Y Yanagitani; H Rakugi; A Okamura; K Moriguchi; S Takiuchi; M Ohishi; K Suzuki; J Higaki; T Ogihara
HYPERTENSION, Jan. 1999 - Inflammatory cell mediated tumour progression and minisatellite mutation correlate with the decrease of antioxidative enzymes in murine fibrosarcoma cells
F. Okada; K. Nakai; T. Kobayashi; T. Shibata; S. Tagami; Y. Kawakami; T. Kitazawa; R. Kominami; S. Yoshimura; K. Suzuki; N. Taniguchi; O. Inanami; M. Kuwabara; H. Kishida; D. Nakae; Y. Konishi; T. Moriuchi; M. Hosokawa
British Journal of Cancer, 1999 - Human erythrocyte bisphosphoglycerate mutase: Inactivation by glycation in vivo and in vitro
T Fujita; K Suzuki; T Tada; Y Yoshihara; R Hamaoka; K Uchida; Y Matuo; T Sasaki; T Hanafusa; N Taniguchi
JOURNAL OF BIOCHEMISTRY, Dec. 1998 - Dysfunction of antioxidative enzymes in the trinitrobenzenesulfonic acid-induced colitis rat
Toshiya Watanabe; Junichi Fujii; Keiichiro Suzuki; Tsuneko Fujii; Michio Asahi; Ken Matsuoka; Naoyuki Taniguchi
Pathophysiology, Dec. 1998 - Gene expression of alpha 1-6 fucosyltransferase in human hepatoma tissues: A possible implication for increased fucosylation of alpha-fetoprotein
K Noda; E Miyoshi; N Uozumi; S Yanagidani; Y Ikeda; CX Gao; K Suzuki; H Yoshihara; M Yoshikawa; K Kawano; N Hayashi; M Hori; N Taniguchi
HEPATOLOGY, Oct. 1998, [Reviewed] - A defect in the mitochondrial import of mutant Mn-superoxide dismutase produced in Sf21 cells
J Fujii; Y Ikeda; T Watanabe; Y Kawasaki; K Suzuki; C Fujii; M Takahashi; N Taniguchi
JOURNAL OF BIOCHEMISTRY, Aug. 1998 - Overexpression of aldehyde reductase protects PC12 cells from the cytotoxicity of methylglyoxal or 3-deoxyglucosone
K Suzuki; YH Koh; H Mizuno; R Hamaoka; N Taniguchi
JOURNAL OF BIOCHEMISTRY, Feb. 1998 - A marked increase in free copper levels in the plasma and liver of LEC rats: An animal model for Wilson disease and liver cancer
M Koizumi; J Fujii; K Suzuki; T Inoue; T Inoue; JMC Gutteridge; N Taniguchi
FREE RADICAL RESEARCH, 1998 - A high expression of heme oxygenase-1 in the liver of LEC rats at the stage of hepatoma: The possible implication of induction in uninvolved tissue
A Matsumoto; R Hanayama; M Nakamura; K Suzuki; J Fujii; H Tatsumi; N Taniguchi
FREE RADICAL RESEARCH, 1998 - High expression of alpha-1-6 fucosyltransferase during rat hepatocarcinogenesis
K Noda; E Miyoshi; N Uozumi; CX Gao; K Suzuki; N Hayashi; M Hori; N Taniguchi
INTERNATIONAL JOURNAL OF CANCER, Jan. 1998 - Induction of apoptotic cell death in human endothelial cells treated with snake venom: Implication of intracellular reactive oxygen species and protective effects of glutathione and superoxide dismutases
K Suzuki; M Nakamura; Y Hatanaka; Y Kayanoki; H Tatsumi; N Taniguchi
JOURNAL OF BIOCHEMISTRY, Dec. 1997 - Chorioamnionitis reduces placental endocrine functions: the role of bacterial lipopolysaccharide and superoxide anion
T Okada; N Matsuzaki; K Sawai; T Nobunaga; K Shimoya; K Suzuki; N Taniguchi; F Saji; Y Murata
JOURNAL OF ENDOCRINOLOGY, Dec. 1997 - Induction of manganese superoxide dismutase by thyroid stimulating hormone in rat thyroid cells
S Nishida; T Nakano; S Kimoto; T Kusunoki; K Suzuki; N Taniguchi; K Murata; TT Tomura
FEBS LETTERS, Oct. 1997 - Effects of endurance training on superoxide dismutase activity, content and mrna expression in rat muscle
S Ohishi; T Kizaki; J Nagasawa; T Izawa; T Komabayashi; N Nagata; K Suzuki; N Taniguchi; H Ohno
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, May 1997 - TGF-beta 1 triggers oxidative modifications and enhances apoptosis in hit cells through accumulation of reactive oxygen species by suppression of catalase and glutathione peroxidase
KN Islam; Y Kayanoki; H Kaneto; K Suzuki; M Asahi; J Fujii; N Taniguchi
FREE RADICAL BIOLOGY AND MEDICINE, 1997 - Reducing sugars trigger oxidative modification and apoptosis in pancreatic beta-cells by provoking oxidative stress through the glycation reaction
H Kaneto; J Fujii; T Myint; N Miyazawa; KN Islam; Y Kawasaki; K Suzuki; M Nakamura; H Tatsumi; Y Yamasaki; N Taniguchi
BIOCHEMICAL JOURNAL, Dec. 1996 - High expression of heparin-binding EGF-like growth factor in rat hepatocarcinogenesis
E Miyoshi; S Higashiyama; T Nakagawa; K Suzuki; M Horimoto; N Hayashi; H Fusamoto; T Kamada; N Taniguchi
INTERNATIONAL JOURNAL OF CANCER, Oct. 1996, [Reviewed] - A role of peroxides in Ca2+ ionophore-induced apoptosis in cultured rat cortical neurons
Y Hatanaka; K Suzuki; Y Kawasaki; Y Endo; N Taniguchi; N Takei
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Oct. 1996 - Glycation and inactivation of sorbitol dehydrogenase in normal and diabetic rats
A Hoshi; M Takahashi; J Fujii; T Myint; H Kaneto; K Suzuki; Y Yamasaki; T Kamada; N Taniguchi
BIOCHEMICAL JOURNAL, Aug. 1996 - The protective role of glutathione peroxidase in apoptosis induced by reactive oxygen species
Y Kayanoki; J Fujii; KN Islam; K Suzuki; S Kawata; Y Matsuzawa; N Taniguchi
JOURNAL OF BIOCHEMISTRY, Apr. 1996 - Glycated Cu,Zn-superoxide dismutase in rat lenses: Evidence for the presence of fragmentation in vivo
Takata, I; N Kawamura; T Myint; N Miyazawa; K Suzuki; N Maruyama; M Mino; N Taniguchi
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Feb. 1996 - Apoptosis induced by nitric oxide in pancreatic beta-cells
H Kaneto; J Fujii; HG Seo; K Suzuki; M Nakamura; H Tatsumi; N Taniguchi
BIOLOGY OF NITRIC OXIDE, PT 5, 1996, [Reviewed] - Inactivation of glutathione peroxidase by nitric oxide: Implication for cytotoxicity
M Asahi; J Fujii; K Suzuki; HG Seo; N Taniguchi
BIOLOGY OF NITRIC OXIDE, PT 5, 1996, [Reviewed] - Superoxide dismutase derivative prevents oxidative damage in liver and kidney of rats induced by exhausting exercise
Z Radak; K Asano; M Inoue; T Kizaki; S OhIshi; K Suzuki; N Taniguchi; H Ohno
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY AND OCCUPATIONAL PHYSIOLOGY, Jan. 1996 - Effects of hypobaric hypoxia on antioxidant enzymes in rats
Nakanishi, I; F Tajima; A Nakamura; SY Yagura; T Ookawara; H Yamashita; K Suzuki; N Taniguchi; H Ohno
JOURNAL OF PHYSIOLOGY-LONDON, Dec. 1995 - Induction of nitric oxide synthase and concomitant suppression of superoxide dismutases in experimental colitis in rats
HG Seo; Takata, I; M Nakamura; H Tatsumi; K Suzuki; J Fujii; N Taniguchi
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Dec. 1995 - AUGMENTATION OF TRANSPORT FOR CISPLATIN-GLUTATHIONE ADDUCT IN CISPLATIN-RESISTANT CANCER-CELLS
S GOTO; K YOSHIDA; T MORIKAWA; Y URATA; K SUZUKI; T KONDO
CANCER RESEARCH, Oct. 1995 - INTERLEUKIN 1-ALPHA-INDUCED EXPRESSION OF MANGANOUS SUPEROXIDE-DISMUTASE REDUCES MYOCARDIAL REPERFUSION INJURY IN THE RAT
C NOGAE; N MAKINO; T HATA; NOGAE, I; S TAKAHASHI; K SUZUKI; N TANIGUCHI; T YANAGA
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Oct. 1995 - IMMUNOLOGICAL DETECTION OF GLYCATED PROTEINS IN NORMAL AND STREPTOZOTOCIN-INDUCED DIABETIC RATS USING ANTI-HEXITOL-LYSINE IGG
T MYINT; S HOSHI; T OOKAWARA; N MIYAZAWA; K SUZUKI; N TANIGUCHI
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, Oct. 1995 - INACTIVATION OF GLUTATHIONE-PEROXIDASE BY NITRIC-OXIDE - IMPLICATION FOR CYTOTOXICITY
M ASAHI; J FUJII; K SUZUKI; HG SEO; T KUZUYA; M HORI; M TADA; S FUJII; N TANIGUCHI
JOURNAL OF BIOLOGICAL CHEMISTRY, Sep. 1995 - SUPEROXIDE-DISMUTASE DERIVATIVE REDUCES OXIDATIVE DAMAGE IN SKELETAL-MUSCLE OF RATS DURING EXHAUSTIVE EXERCISE
Z RADAK; K ASANO; M INOUE; T KIZAKI; S OHISHI; K SUZUKI; N TANIGUCHI; H OHNO
JOURNAL OF APPLIED PHYSIOLOGY, Jul. 1995 - APOPTOTIC CELL-DEATH TRIGGERED BY NITRIC-OXIDE IN PANCREATIC BETA-CELLS
H KANETO; J FUJII; HG SEO; K SUZUKI; T MATSUOKA; M NAKAMURA; H TATSUMI; Y YAMASAKI; T KAMADA; N TANIGUCHI
DIABETES, Jul. 1995 - MITOCHONDRIAL LIPID-PEROXIDATION AND SUPEROXIDE-DISMUTASE IN RAT HYPERTENSIVE TARGET ORGANS
T OHTSUKI; M MATSUMOTO; K SUZUKI; N TANIGUCHI; T KAMADA
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, Apr. 1995 - Physical exercise and superoxide dismutase isoenzymes in rat skeletal muscle.
Oh-ishi S; Yamashita H; Kizaki T; Nagasawa J; Sagawa M; Nagata N; Izawa T; Komabayashi T; Suzuki K; Taniguchi N; Ohno H
Proceedings FISU/CESU Conference, 1995, [Reviewed] - Changes in immunoreactive manganese-superoxide dismutase content in rat tissues under heat or cold environment
Tomomi Ookawara; Takako Kizaki; Hitoshi Yamashita; Shuji Oh-ishi; Daizoh Saitoh; Keiichiro Suzuki; Naoyuki Taniguchi; Hideko Ohno
Pathophysiology, 1995 - Alteration of superoxide dismutase iso-enzyme activity,content,and mRNA expression with aging in rat skeletal muscle.(共著)
Mechanisms of Ageing and Development, 1995 - OXIDATIVE STRESS-INDUCED BY INTERMITTENT EXPOSURE AT A SIMULATED ALTITUDE OF 4000-M DECREASES MITOCHONDRIAL SUPEROXIDE-DISMUTASE CONTENT IN SOLEUS MUSCLE OF RATS
Z RADAK; K LEE; W CHOI; S SUNOO; T KIZAKI; S OHISHI; K SUZUKI; N TANIGUCHI; H OHNO; K ASANO
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY AND OCCUPATIONAL PHYSIOLOGY, Nov. 1994 - DNA CLEAVAGE INDUCED BY GLYCATION OF CU,ZN-SUPEROXIDE DISMUTASE
H KANETO; J FUJII; K SUZUKI; H KASAI; R KAWAMORI; T KAMADA; N TANIGUCHI
BIOCHEMICAL JOURNAL, Nov. 1994 - IMMUNOHISTOCHEMICAL EXPRESSION OF MANGANESE SUPEROXIDE-DISMUTASE IN HEPATOCELLULAR-CARCINOMA, USING A SPECIFIC MONOCLONAL-ANTIBODY
Y AIDA; S MAEYAMA; T TAKAKUWA; T UCHIKOSHI; Y ENDO; K SUZUKI; N TANIGUCHI
JOURNAL OF GASTROENTEROLOGY, Aug. 1994, [Reviewed] - SUPPRESSION OF ANTIOXIDATIVE ENZYME EXPRESSION BY TRANSFORMING GROWTH-FACTOR-BETA-1 IN RAT HEPATOCYTES
Y KAYANOKI; J FUJII; K SUZUKI; S KAWATA; Y MATSUZAWA; N TANIGUCHI
JOURNAL OF BIOLOGICAL CHEMISTRY, Jun. 1994 - EFFECTS OF CYTOKINES AND ENDOTOXIN ON LUNG MANGANESE SUPEROXIDE-DISMUTASE EXPRESSION AND IMMUNOHISTOCHEMICAL DISTRIBUTION
CW WHITE; Y LEWISMOLOCK; K SUZUKI; N TANIGUCHI; H SHIMIZU; DH NGUYEN; RJ MASON
CHEST, Mar. 1994, [Reviewed] - NITRIC-OXIDE SYNTHASE FROM RAT COLORECTUM - PURIFICATION, PEPTIDE SEQUENCING, PARTIAL PCR CLONING, AND IMMUNOHISTOCHEMISTRY
HG SEO; H TATSUMI; J FUJII; A NISHIKAWA; K SUZUKI; K KANGAWA; N TANIGUCHI
JOURNAL OF BIOCHEMISTRY, Mar. 1994 - LUNG MANGANESE SUPEROXIDE-DISMUTASE INCREASES DURING CYTOKINE-MEDIATED PROTECTION AGAINST PULMONARY OXYGEN-TOXICITY IN RATS
Y LEWISMOLOCK; K SUZUKI; N TANIGUCHI; DDH NGUYEN; RJ MASON; CW WHITE
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, Feb. 1994 - LOCALIZATION, MECHANISM OF INDUCTION AND RELEASE INTO SERUM OF MANGANESE SUPEROXIDE-DISMUTASE IN HUMAN UMBILICAL ENDOTHELIAL-CELLS
K SUZUKI; H TATSUMI; S SATOH; T SENDA; T NAKATA; J FUJII; N TANIGUCHI
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, [Reviewed] - CHARACTERIZATION OF HUMAN MN-SOD AND CU,ZN-SOD EXPRESSED IN BACULOVIRUS-INSECT CELL SYSTEM
J FUJII; Y IKEDA; K SUZUKI; N TANIGUCHI
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, [Reviewed] - FRAGMENTATION OF CU,ZN-SOD AND DNA CLEAVAGE INDUCED BY GLYCATION REACTION
H KANETO; T OOKAWARA; J FUJII; K SUZUKI; N TANIGUCHI
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, [Reviewed] - INHIBITORY EFFECTS OF HYPOXIC PRECONDITIONING ON MYOCARDIAL-CELL INJURY AT LATE-PHASE ARE CLOSELY LINKED TO AN INCREASE IN MN-SOD ACTIVITY OF RAT NEONATAL CARDIAC MYOCYTES
N YAMASHITA; T KUZUYA; S HOSHIDA; M NISHIDA; H OE; K SUZUKI; N TANIGUCHI; M HORI; T KAMADA; M TADA
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, [Reviewed] - TRANSFORMING GROWTH-FACTOR-BETA SUPPRESSES EXPRESSION OF ANTIOXIDATIVE ENZYMES IN RAT HEPATOCYTES
Y KAYANOKI; J FUJII; K SUZUKI; Y AIDA; T UCHIKOSHI; S KAWATA; Y MATSUZAWA; N TANIGUCHI
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, [Reviewed] - REGULATION OF HUMAN MN-SOD GENE-EXPRESSION BY CYTOKINES AND OTHER FACTORS
J FUJII; Y KAYANOKI; K SUZUKI; N TANIGUCHI
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, [Reviewed] - CHANGES IN IMMUNOREACTIVE MANGANESE-SUPEROXIDE DISMUTASE LEVEL IN RAT-TISSUES UNDER HYPOBARIC-HYPOXIC ENVIRONMENT
K NAKANISHI; F TAJIMA; A NAKAMURA; T OOKAWARA; H YAMASHITA; K SUZUKI; N TANIGUCHI; H OHNO
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, [Reviewed] - EFFECTS OF COLD OR HEAT ENVIRONMENT ON IMMUNOREACTIVE MANGANESE-SUPEROXIDE DISMUTASE IN RAT-TISSUES
T OOKAWARA; T KIZAKI; H YAMASHITA; S OHISHI; Y OHIRA; K SUZUKI; N TANIGUCHI; Y SATO; H OHNO
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994 - Immunohistochemical Expression of Manganese Superoxide Dismutase in Hepatocellular Carcinoma, Using A Specific Monoclonal Antibody. (共著)
Journal of Gastroenterology, 1994 - Immunoreactivity and activity of mitochondrial superoxide dismutase following training and exercise
Chandan K. Sen; Tomomi Ookawara; Keiichiro Suzuki; Naoyuki Taniguchi; Osmo Hänninen; Hideki Ohno
Pathophysiology, 1994 - EXPRESSION OF MANGANESE SUPEROXIDE-DISMUTASE IS NOT ALTERED IN TRANSGENIC MICE WITH ELEVATED LEVEL OF COPPER-ZINC SUPEROXIDE-DISMUTASE
CW WHITE; DDH NGUYEN; K SUZUKI; N TANIGUCHI; LS RUSAKOW; KB AVRAHAM; Y GRONER
FREE RADICAL BIOLOGY AND MEDICINE, Dec. 1993 - INDUCTION AND RELEASE OF MANGANESE SUPEROXIDE-DISMUTASE FROM MITOCHONDRIA OF HUMAN UMBILICAL VEIN ENDOTHELIAL-CELLS BY TUMOR-NECROSIS-FACTOR-ALPHA AND INTERLEUKIN-1-ALPHA
T NAKATA; K SUZUKI; J FUJII; M ISHIKAWA; N TANIGUCHI
INTERNATIONAL JOURNAL OF CANCER, Oct. 1993 - MANGANESE-SUPEROXIDE DISMUTASE IN ENDOTHELIAL-CELLS - LOCALIZATION AND MECHANISM OF INDUCTION
K SUZUKI; H TATSUMI; S SATOH; T SENDA; T NAKATA; J FUJII; N TANIGUCHI
AMERICAN JOURNAL OF PHYSIOLOGY, Oct. 1993 - HIGH COPPER AND IRON LEVELS AND EXPRESSION OF MN-SUPEROXIDE DISMUTASE IN MUTANT RATS DISPLAYING HEREDITARY HEPATITIS AND HEPATOMA (LEC RATS)
K SUZUKI; N MIYAZAWA; T NAKATA; HG SEO; T SUGIYAMA; N TANIGUCHI
CARCINOGENESIS, Sep. 1993 - EFFECT OF TRANSIENT FOREBRAIN ISCHEMIA ON SUPEROXIDE DISMUTASES IN GERBIL HIPPOCAMPUS
T OHTSUKI; M MATSUMOTO; K SUZUKI; N TANIGUCHI; T KAMADA
BRAIN RESEARCH, Aug. 1993 - IDENTITY OF A MAJOR 3-DEOXYGLUCOSONE-REDUCING ENZYME WITH ALDEHYDE REDUCTASE IN RAT-LIVER ESTABLISHED BY AMINO-ACID SEQUENCING AND CDNA EXPRESSION
M TAKAHASHI; J FUJII; T TESHIMA; K SUZUKI; T SHIBA; N TANIGUCHI
GENE, May 1993 - RESPONSES OF HUMAN GLIOBLASTOMA CELLS TO HUMAN NATURAL TUMOR-NECROSIS-FACTOR-ALPHA - SUSCEPTIBILITY, MECHANISM OF RESISTANCE AND CYTOKINE PRODUCTION STUDIES
S SAKUMA; Y SAWAMURA; M TADA; T AIDA; H ABE; K SUZUKI; N TANIGUCHI
JOURNAL OF NEURO-ONCOLOGY, Mar. 1993 - MANGANESE SUPEROXIDE-DISMUTASE CONTENT AND LOCALIZATION IN HUMAN THYROID-TUMORS
S NISHIDA; F AKAI; H IWASAKI; K HOSOKAWA; T KUSUNOKI; K SUZUKI; N TANIGUCHI; S HASHIMOTO; TT TAMURA
JOURNAL OF PATHOLOGY, Mar. 1993 - ULTRASTRUCTURAL-LOCALIZATION OF SUPEROXIDE-DISMUTASE IN HUMAN SKIN
T KOBAYASHI; N SAITO; N TAKEMORI; S IIZUKA; K SUZUKI; N TANIGUCHI; H IIZUKA
ACTA DERMATO-VENEREOLOGICA, Feb. 1993 - A ROLE FOR MANGANESE SUPEROXIDE-DISMUTASE IN RADIOPROTECTION OF HEMATOPOIETIC STEM-CELLS BY INTERLEUKIN-1
J EASTGATE; J MOREB; HS NICK; K SUZUKI; N TANIGUCHI; ZUCALI, JR
BLOOD, Feb. 1993 - GLYCATION OF CU, ZN-SUPEROXIDE DISMUTASE AND ITS CONSEQUENCES
T OOKAWARA; S HOSHI; T MYINT; K SUZUKI; N TANIGUCHI
PERSPECTIVE BIOLOGY, 1993, [Reviewed] - SUBLETHAL ISCHEMIA ALTERS MYOCARDIAL ANTIOXIDANT ACTIVITY IN CANINE HEART
S HOSHIDA; T KUZUYA; H FUJI; N YAMASHITA; H OE; M HORI; K SUZUKI; N TANIGUCHI; M TADA
AMERICAN JOURNAL OF PHYSIOLOGY, Jan. 1993 - INFLUENCE OF OXIDATIVE STRESS ON INDUCED TOLERANCE TO ISCHEMIA IN GERBIL HIPPOCAMPAL-NEURONS
T OHTSUKI; M MATSUMOTO; K KUWABARA; K KITAGAWA; K SUZUKI; N TANIGUCHI; T KAMADA
BRAIN RESEARCH, Dec. 1992 - EXPRESSION OF MN-SUPEROXIDE DISMUTASE IN CARCINOGENESIS
N TANIGUCHI; M ISHIKAWA; T KAWAGUCHI; J FUJII; K SUZUKI; T NAKATA
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, Oct. 1992 - HIGH EXPRESSION OF MANGANESE SUPEROXIDE-DISMUTASE IN 7,12-DIMETHYLBENZ[A]ANTHRACENE-INDUCED OVARIAN-CANCER AND INCREASED SERUM LEVELS IN THE TUMOR-BEARING RATS
T NAKATA; K SUZUKI; J FUJII; M ISHIKAWA; H TATSUMI; T SUGIYAMA; T NISHIDA; T SHIMIZU; M YAKUSHIJI; N TANIGUCHI
CARCINOGENESIS, Oct. 1992 - DISTRIBUTION OF MANGANESE SUPEROXIDE-DISMUTASE IN RAT STOMACH - APPLICATION OF TRITON X-100 AND SUPPRESSION OF ENDOGENOUS STREPTAVIDIN BINDING-ACTIVITY
S SATOH; H TATSUMI; K SUZUKI; N TANIGUCHI
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, Aug. 1992 - INCREASED GLYCATED CU,ZN-SUPEROXIDE DISMUTASE LEVELS IN ERYTHROCYTES OF PATIENTS WITH INSULIN-DEPENDENT DIABETES-MELLITUS
N KAWAMURA; T OOKAWARA; K SUZUKI; K KONISHI; M MINO; N TANIGUCHI
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, Jun. 1992 - ELEVATED SERUM MANGANESE SUPEROXIDE-DISMUTASE IN ACUTE LEUKEMIAS
T NISHIURA; K SUZUKI; T KAWAGUCHI; H NAKAO; N KAWAMURA; M TANIGUCHI; Y KANAYAMA; T YONEZAWA; N TANIGUCHI
CANCER LETTERS, Mar. 1992 - INDUCTION OF MN-SOD AND CU, ZN-SOD AFTER TRANSIENT FOREBRAIN ISCHEMIA AND ISCHEMIC TOLERANCE
T OHTSUKI; M MATSUMOTO; K SUZUKI; K KIMURA; N TANIGUCHI; T KAMADA
OXYGEN RADICALS, 1992, [Reviewed] - INDUCED TOLERANCE TO FOLLOWING ISCHEMIC NEURONAL DAMAGES BY PRECEDING OXYGEN RADICAL STRESS
T OHTSUKI; M MATSUMOTO; K KUWABARA; K SUZUKI; K KIMURA; N TANIGUCHI; T KAMADA
OXYGEN RADICALS, 1992, [Reviewed] - Elevation of immunoreactive serum mn-superoxide dismutase in patients with acute myocardial infarction
Keiichiro Suzuki; Noriaki Kinoshita; Yukihiko Matsuda; Shigeki Higashiyama; Tsunehiko Kuzuya; Takazo Minamino; Michihiko Tada; Naoyuki Taniguchi
Free Radical Research, 1992, [Reviewed] - HIGH-LEVELS OF MN-SUPEROXIDE DISMUTASE IN SERUM OF PATIENTS WITH NEUROBLASTOMA AND IN HUMAN NEUROBLASTOMA CELL-LINES
N KAWAMURA; K SUZUKI; M ISHIKAWA; S IIZUKA; M MIYAKE; M MINO; N TANIGUCHI
FREE RADICAL BIOLOGY AND MEDICINE, 1992 - ELEVATION OF IMMUNOREACTIVE SERUM MN-SUPEROXIDE DISMUTASE IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION
K SUZUKI; N KINOSHITA; Y MATSUDA; S HIGASHIYAMA; T KUZUYA; T MINAMINO; M TADA; N TANIGUCHI
FREE RADICAL RESEARCH COMMUNICATIONS, 1992 - ELEVATED LEVEL OF SERUM MN-SUPEROXIDE DISMUTASE IN PATIENTS WITH PRIMARY BILIARY-CIRRHOSIS - POSSIBLE INVOLVEMENT OF FREE-RADICALS IN THE PATHOGENESIS IN PRIMARY BILIARY-CIRRHOSIS
M ONO; C SEKIYA; M OHHIRA; M OHHIRA; M NAMIKI; Y ENDO; K SUZUKI; Y MATSUDA; N TANIGUCHI
JOURNAL OF LABORATORY AND CLINICAL MEDICINE, Nov. 1991 - SUPEROXIDE-DISMUTASE IN PSORIASIS, SQUAMOUS-CELL CARCINOMA AND BASAL-CELL EPITHELIOMA - AN IMMUNOHISTOCHEMICAL STUDY
T KOBAYASHI; M MATSUMOTO; H IIZUKA; K SUZUKI; N TANIGUCHI
BRITISH JOURNAL OF DERMATOLOGY, Jun. 1991 - LOCALIZATION OF MN-SUPEROXIDE DISMUTASE (MN-SOD) IN CHOLINERGIC AND SOMATOSTATIN-CONTAINING NEURONS IN THE RAT NEOSTRIATUM
S INAGAKI; K SUZUKI; N TANIGUCHI; H TAKAGI
BRAIN RESEARCH, May 1991 - PREPARATION OF HUMAN MANGANESE SUPEROXIDE-DISMUTASE BY TRI-PHASE PARTITIONING AND PRELIMINARY CRYSTALLOGRAPHIC DATA
HF DEUTSCH; S HOSHI; Y MATSUDA; K SUZUKI; K KAWANO; Y KITAGAWA; Y KATSUBE; N TANIGUCHI
JOURNAL OF MOLECULAR BIOLOGY, May 1991 - INTENSE IMMUNOREACTIVITY FOR MN-SUPEROXIDE DISMUTASE (MN-SOD) IN CHOLINERGIC AND NONCHOLINERGIC NEURONS IN THE RAT BASAL FOREBRAIN
S INAGAKI; H TAKAGI; K SUZUKI; F AKAI; N TANIGUCHI
BRAIN RESEARCH, Feb. 1991 - Post-Embedding Immuno-Electron Microscopy with Rapid Freezing and Freeze-Substitution Techniques for the Localization of Manganese Superoxide Dismutase
Haruyuki Tatsumi; Shoji Satoh; Keiichiro Suzuki; Naoyuki Taniguchi; Takao Senda; Hisao Fujita
Archives of Histology and Cytology, 1991 - A three-step purification of manganese superoxide dismutase from human liver on both large and small scales
Yukihiko Matsuda; Keiichiro Suzuki; Tomomi Ookawara; Toshiyuki Nakata; Han-Geuk Seo; Sumio Kawata; Seiichiro Tarui; Harold F. Deutsch; Naoyuki Taniguchi
Protein Expression and Purification, 1991 - HUMAN LIVER MANGANESE SUPEROXIDE-DISMUTASE - PURIFICATION AND CRYSTALLIZATION, SUBUNIT ASSOCIATION AND SULFHYDRYL REACTIVITY
Y MATSUDA; S HIGASHIYAMA; Y KIJIMA; K SUZUKI; K KAWANO; M AKIYAMA; S KAWATA; S TARUI; HF DEUTSCH; N TANIGUCHI
EUROPEAN JOURNAL OF BIOCHEMISTRY, Dec. 1990 - STIMULATION OF MN-SUPEROXIDE DISMUTASE EXPRESSION BY TUMOR NECROSIS FACTOR-ALPHA - QUANTITATIVE-DETERMINATION OF MN-SOD PROTEIN-LEVELS IN TNF-RESISTANT AND SENSITIVE CELLS BY ELISA
T KAWAGUCHI; A TAKEYASU; K MATSUNOBU; T UDA; M ISHIZAWA; K SUZUKI; T NISHIURA; M ISHIKAWA; N TANIGUCHI
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Sep. 1990 - IMMUNOCYTOCHEMICAL LOCALIZATION OF MANGANESE SUPEROXIDE-DISMUTASE (MN-SOD) IN THE HIPPOCAMPUS OF THE RAT
F AKAI; M MAEDA; K SUZUKI; S INAGAKI; H TAKAGI; N TANIGUCHI
NEUROSCIENCE LETTERS, Jul. 1990 - SERUM-MANGANESE-SUPEROXIDE DISMUTASE - NORMAL VALUES AND INCREASED LEVELS IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION AND SEVERAL MALIGNANT DISEASES DETERMINED BY AN ENZYME-LINKED-IMMUNOSORBENT-ASSAY USING A MONOCLONAL-ANTIBODY
T KAWAGUCHI; K SUZUKI; Y MATSUDA; T NISHIURA; T UDA; M ONO; C SEKIYA; M ISHIKAWA; S IINO; Y ENDO; N TANIGUCHI
JOURNAL OF IMMUNOLOGICAL METHODS, Mar. 1990 - SELECTIVE EXPRESSION AND INDUCTION OF CYTOCHROME P450PB AND P450MC DURING THE DEVELOPMENT OF HEREDITARY HEPATITIS AND HEPATOMA OF LEC RATS
T SUGIYAMA; K SUZUKI; T OOKAWARA; T KUROSAWA; N TANIGUCHI
CARCINOGENESIS, Nov. 1989, [Reviewed] - POLYMORPHONUCLEAR LEUKOCYTE ACTIVITY AND VENTRICULAR ARRHYTHMIA IN ACUTE MYOCARDIAL-INFARCTION
T KUZUYA; S HOSHIDA; K SUZUKI; T SASAKI; A KITABATAKE; T KAMADA; T MINAMINO; M TADA
AMERICAN JOURNAL OF CARDIOLOGY, Nov. 1988 - IMMEDIATE AND LONG-TERM PROGNOSES OF ACUTE MYOCARDIAL-INFARCTION - ANALYSIS OF DETERMINANTS OF PROGNOSIS
S FUKUI; A TANI; Y HAMANO; O KATOH; K SUZUKI; T MINAMINO
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, Mar. 1987 - PATHOGENESIS OF IMPENDING MYOCARDIAL-INFARCTION AND ACUTE MYOCARDIAL-INFARCTION - CLINICAL AND ANGIOGRAPHIC EVALUATION OF CORONARY-THROMBOSIS AS A PRECIPITATING FACTOR
O KATOH; K GOTOH; H TATEYAMA; K SUZUKI; Y YASUMURA; S OHNISHI; K FUJII; Y HAMANO; S FUKUI; T MINAMINO
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, Feb. 1986
MISC
- SOD1欠損マウスにおける脳内モノアミン代謝の変化と行動異常
吉原大作; 藤原範子; 北中順惠; 北中純一; 江口裕伸; 崎山晴彦; 竹村基彦; 鈴木敬一郎
日本酸化ストレス学会学術集会プログラム・抄録集, 2022 - ALS原因タンパク質であるSOD1の凝集体形成に必要なアミノ酸配列の同定
東野智行; 浅井新喜; 矢埜杏果; 吉原大作; 江口裕伸; 崎山晴彦; 藤原範子; 鈴木敬一郎
日本生化学会大会(Web), 2022 - 鉄欠乏状態におけるRedox cycling quinone:DMNQによる細胞傷害
吉原大作; 藤原範子; 江口裕伸; 崎山晴彦; 鈴木敬一郎
日本酸化ストレス学会学術集会プログラム・抄録集, 2021 - 転写因子ChREBP欠損マウスにおける抗肥満効果に関する研究
崎山晴彦; LAN Li; 中川勉; 江口裕伸; 吉原大作; 藤原範子; 鈴木敬一郎
日本酸化ストレス学会学術集会プログラム・抄録集, 2019 - ChREBP-KOマウスの褐色脂肪組織における脂質代謝と熱産生に関する研究
黎蘭; 崎山晴彦; 中川勉; 江口裕伸; 吉原大作; 藤原範子; 鈴木敬一郎
日本分子生物学会年会プログラム・要旨集(Web), 2019 - スーパーオキシド産生剤DMNQによる細胞内の鉄動態の変化
吉原大作; 藤原範子; 平山祐; 丹羽正人; 江口裕伸; 崎山晴彦; 永澤秀子; 鈴木敬一郎
日本鉄バイオサイエンス学会学術集会プログラム・抄録集, 2019 - 酸化ストレスが鉄代謝異常を引き起こす機序の解析
吉原大作; 藤原範子; 平山祐; 丹羽正人; 江口裕伸; 崎山晴彦; 永澤秀子; 鈴木敬一郎
日本鉄バイオサイエンス学会学術集会プログラム・抄録集, 2018 - 転写因子ChREBP欠損マウスにおける抗肥満効果に関する研究
崎山晴彦; RAN Li; 中川勉; 江口裕伸; 吉原大作; 藤原範子; 鈴木敬一郎
日本メイラード学会学術集会プログラム・抄録集, 2018 - ALS原因タンパク質であるSOD1の線維化やゲル化には適度な水分子を含む伸びた中間体が必要である
藤原範子; 我妻美千留; 大場矢登; 吉原大作; 徳田栄一; 江口裕伸; 崎山晴彦; 井上正志; 古川良明; 鈴木敬一郎
日本生化学会大会(Web), 2018 - 酸化ストレスが細胞内の鉄イオン動態に与える影響
吉原 大作; 藤原 範子; 平山 祐; 丹羽 正人; 江口 裕伸; 崎山 晴彦; 永澤 秀子; 鈴木 敬一郎
生命科学系学会合同年次大会, Dec. 2017 - Development of preventive and therapeutic drugs for lifestyle-related diseases targeting ChREBP
崎山 晴彦; 中川 勉; 江口 裕伸; 吉原 大作; 藤原 範子; 鈴木 敬一郎
細胞, Feb. 2017 - ALS原因タンパク質であるSOD1の線維ゲル形成とその物性
藤原範子; 我妻美千留; 大場矢登; 吉原大作; 徳原栄一; 江口裕伸; 崎山晴彦; 井上正志; 古川良明; 鈴木敬一郎
日本生化学会大会(Web), 2017 - 酸化ストレスによる細胞死の誘導と鉄イオン動態の変化
吉原大作; 藤原範子; 平山祐; 丹羽正人; 江口裕伸; 崎山晴彦; 永澤秀子; 鈴木敬一郎
日本鉄バイオサイエンス学会学術集会プログラム・抄録集, 2017 - Solution oxygen-17 NMR application for observing a peroxidized cysteine residue in oxidized human SOD1
Noriko Fujiwara; Daisaku Yoshihara; Haruhiko Sakiyama; Hironobu Eguchi; Keiichiro Suzuki
HYPERFINE INTERACTIONS, Aug. 2016 - Antioxidant use in humans - Successes and failures
Hironobu Eguchi; Haruhiko Sakiyama; Daisaku Yoshihara; Noriko Fujiwara; Keiichiro Suzuki
Systems Biology of Free Radicals and Antioxidants, 01 May 2012 - Oxidation of Cys111 residue in loop VI of human copper/zinc superoxide dismutase
Fujiwara Noriko; Ihara Kentaro; Kato Shinsuke; Yoshihara Daisaku; Eguchi Hironobu; Sakiyama Haruhiko; Wakatsuki Soichi; Taniguchi Naoyuki; Suzuki Keiichiro
AMINO ACIDS, Jul. 2011, [Reviewed] - The role of O-linked GlcNAc modification on the glucose response of ChREBP
Sakiyama Haruhiko; Fujiwara Noriko; Noguchi Takahiro; Eguchi Hironobu; Yoshihara Daisaku; Suzuki Keiichiro
AMINO ACIDS, Jul. 2011, [Reviewed] - Benefits and risks of antioxidants for health
Daisaku Yoshihara; Noriko Fujiwara; Keiichiro Suzuki
Maturitas, 01 Dec. 2010 - Cardiac dysfunction caused by O-GlcNAcylation of phospholamban
Shunichi Yokoe; Takatoshi Nakagawa; Keiichiro Suzuki; Michio Asahi
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010 - Oxidative stress and health
江口 裕伸; 藤原 範子; 大河原 知水
生物試料分析 = Journal of analytical bio-science, Sep. 2009 - Anti-oxidants for therapeutic use: Why are only a few drugs in clinical use?
Keiichiro Suzuki
ADVANCED DRUG DELIVERY REVIEWS, Apr. 2009 - ALSにおける酸化ストレスおよび酸化型SOD1の関与
藤原範子; 松本紋子; 鈴木敬一郎; 谷口直之
実験医学(増刊)『病態解明に迫る活性酸素シグナルと酸化ストレス』（谷口直之監修）, 2009 - 筋萎縮性側索硬化症の画期的診断・治療法に関する研究 SOD1のCys111残基の酸化とALS治療ターゲットへの可能性
谷口直之; 藤原範子; 中の三弥子; 松本紋子; 鈴木敬一郎
筋萎縮性側索硬化症の画期的診断・治療法に関する研究 平成19年度 総括研究報告書, 2008 - 筋萎縮性側索硬化症の画期的診断・治療法に関する研究 変異SOD1の構造学的特性と酸化型SOD1のALSへの関与
谷口直之; 藤原範子; 中の三弥子; 高宮里奈; 松本紋子; 鈴木敬一郎
筋萎縮性側索硬化症の画期的診断・治療法に関する研究 平成17-19年度 総合研究報告書, 2008 - Effects of copper metabolism on neurologigal functions in Wistar and LEC rats
Daisaku Yoshihara; Noriko Fujiwara; Hiroyuki Iso; Nobue Kitanaka; Junichi Kitanaka; Hironobu Eguchi; Tomomi Ookawara; Keiichiro Ozawa; Shigero Shimoda; Motohiko Takemura; Keiichiro Suzuki
NEUROSCIENCE RESEARCH, 2007 - Role of Cys111 in an oxidative damage of human Cu/Zn-superoxide dismutase
Noriko Fujiwara; Miyako Nakano; Daisaku Yoshihara; Tomomi Ookawara; Hironobu Eguchi; Naoyuki Taniguchi; Keiichiro Suzuki
NEUROSCIENCE RESEARCH, 2007 - Overexpression of mutated Cu, Zn-SOD in neuroblastoma cells results in cytoskeletal change (vol 288, pg C253, 2005)
R Takamiya; M Takahashi; YS Park; Y Tawara; N Fujiwara; Y Miyamoto; J Gu; K Suzuki; N Taniguchi
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, Jun. 2005 - Specific cleavage of carbohydrates by reactive oxygen species.
Eguchi H; Ikeda Y; Ookawara T; Fujiwara N; Taniguchi N; Suzuki K
Natural Antioxidants and Micronutrients, 2005 - Induction of manganese superoxide dismutase by IL-1 beta in rat aortic smooth muscle cells; significance of IL-1 beta-induced nitric oxide in vascular system
M Asahi; K Otsu; N Yamashita; K Suzuki; N Taniguchi
NITRIC OXIDE-BIOLOGY AND CHEMISTRY, Aug. 2004 - Nitric oxide enhances the internalization of extracellular superoxide dismutase
H Eguchi; T Ookawara; N Fujiwara; J Yasuda; S Kojima; M Nishimura; M Nanami; K Suzuki
NITRIC OXIDE-BIOLOGY AND CHEMISTRY, Aug. 2004 - Aging Theories in Molecular Biology and Biochemistry
Keiichiro Suzuki; Naoyuki Taniguchi
Neuro-Ophthalmology Japan, 2004 - Desialylation of cell surface oligosaccharides by reactive oxygen species
H Eguchi; Y Ikeda; T Ookawara; N Fujiwara; J Yasuda; S Kojima; N Taniguchi; K Suzuki
FREE RADICAL BIOLOGY AND MEDICINE, 2004 - An inter-subunit disulfide bond affects affinity of human lung extracellular superoxide dismutase to heparin
T Ookawara; H Eguchi; T Kizaki; C Nakao; Y Sato; N Imazeki; O Matsubara; H Ohno; K Suzuki
FREE RADICAL RESEARCH, Aug. 2003 - An inter-subunit disulfide bond affects affinity of human lung extracellular superoxide dismutase to heparin
T Ookawara; H Eguchi; T Kizaki; C Nakao; Y Sato; N Imazeki; O Matsubara; H Ohno; K Suzuki
FREE RADICAL RESEARCH, Aug. 2003 - Effects of oxidative stress on the nuclear translocation of extracellular superoxide dismutase
T Ookawara; H Eguchi; M Nishimura; T Kizaki; E Takayama; D Saitoh; H Ohno; K Suzuki
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2003 - Oxidative stress caused by inactivation of glutathione peroxidase and adaptive responses
Y Miyamoto; YH Koh; YS Park; N Fujiwara; H Sakiyama; Y Misonou; T Ookawara; K Suzuki; K Honke; N Taniguchi
BIOLOGICAL CHEMISTRY, Apr. 2003 - Effects of oxidative stress on the nuclear translocation of extracellular superoxide dismutase
T Ookawara; H Eguchi; M Nishimura; T Kizaki; E Takayama; D Saitoh; H Ohno; K Suzuki
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2003 - Gliclazide protects pancreatic beta-cells from damage by hydrogen peroxide
K Kimoto; K Suzuki; T Kizaki; Y Hitomi; H Ishida; H Katsuta; E Itoh; T Ookawara; K Suzuki; K Honke; H Ohno
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Mar. 2003 - Physical Exercise and Extracellular Superoxide Dismutase: Antiatherogenic Effects :
OHNO Hideki; KIZAKI Takako; SUZUKI Kenji; HITOMI Yoshiaki; WATANABE Sumiko; OOKAWARA Tomomi; SUZUKI Keiichiro; HAGA Shukoh; SAITOH Daizoh; RADAK Zsolt; JI Li Li
Advances in exercise and sports physiology, 2003 - Physical exercise and extracellular superoxide dismutase.
OHNO Hideki; KIZAKI Takako; SUZUKI Kenji; HITOMI Yoshiaki; WATANABE Sumiko; OOKAWARA Tomomi; SUZUKI Keiichiro; HAGA Shukoh; SAITOH Daizoh; RADAK Zsolt; JI Li Li
Adv Exerc Sports Physiol., 2003 - Identification of the binding site of methylglyoxal on glutathione peroxidase: Methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185
YS Park; YH Koh; M Takahashi; Y Miyamoto; K Suzuki; N Dohmae; K Takio; K Honke; N Taniguchi
FREE RADICAL RESEARCH, 2003 - Induction of thioredoxin reductase gene expression by peroxynitrite in human umbilical vein endothelial cells
YS Park; N Fujiwara; YH Koh; Y Miyamoto; K Suzuki; K Honke; N Taniguchi
BIOLOGICAL CHEMISTRY, Mar. 2002 - Oxidative damage due to copper ion and hydrogen peroxide induces GlcNAc-Specific cleavage of an asn-linked oligosaccharide
H Eguchi; Y Ikeda; S Koyota; K Honke; K Suzuki; J Gutteridge; N Taniguchi
JOURNAL OF BIOCHEMISTRY, Mar. 2002 - Enzyme-linked immunosorbent assay for human and rat manganese superoxide dismutases
K Suzuki; T Ookawara; Y Miyamoto; N Taniguchi
SUPEROXIDE DISMUTASE, 2002 - Enzyme-linked immunosorbent assay for human and rat manganese superoxide dismutases
Keiichiro Suzuki; Tomomi Ookawara; Yasuhide Miyamoto; Naoyuki Taniguchi
Methods in Enzymology, 2002 - Dye terminator re-cycle-sequencing method: Phage plaque direct sequencing
H Obata; T Tanaka; T Fujii; C Sasho; Y Yamaguchi; K Suzuki
ANALYTICAL BIOCHEMISTRY, Oct. 2001 - Osmotic stress induces HB-EGF gene expression via Ca2+/Pyk2/JNK signal cascades in rat aortic smooth muscle cells
YH Koh; WY Che; S Higashiyama; M Takahashi; Y Miyamoto; K Suzuki; N Taniguchi
JOURNAL OF BIOCHEMISTRY, Sep. 2001 - 活性酸素の糖鎖構造に及ぼす影響
江口 裕伸; 池田 義孝; 小代田 宗一; 本家 孝一; 谷口 直之; 鈴木 敬一郎
生化学, Aug. 2001 - 糖尿病・動脈硬化とフリーラジカル
鈴木 敬一郎; 谷口 直之
The Lipid, Jan. 2001 - Thioredoxin reductase gene expression by reactive nitrogen species in human umbilical vein endothelial cells.
YS Park; N Fujiwara; YH Koh; Y Miyamoto; K Suzuki; N Taniguchi
FREE RADICAL BIOLOGY AND MEDICINE, 2001 - Nitric oxide induces gene expression of heparin-binding epidermal growth factor-like growth factor(HB-EGF) in rat aortic smooth muscle cells: Its mechanism and anti-apoptotic effect.
K Suzuki; YH Koh; YS Park; N Taniguchi
FREE RADICAL BIOLOGY AND MEDICINE, 2001 - 活性酸素の作用と消去 活性酸素による細胞接着の変化 蛋白新規合成阻害下での血管内皮細胞に対する好中球/癌細胞の接着性の亢進
鈴木 敬一郎; 江口 裕伸; 大河原 知水; 谷口 直之
生物物理化学, Dec. 2000 - Osmotic stressによるヘパリン結合成EGF様増殖因子(HB-EGF)の発現誘導と作用機序
高 永鎬; 車 文一; 鈴木 敬一郎; 朴 用軾; 高橋 素子; 東山 繁樹; 谷口 直之
生化学, Aug. 2000 - 3-デオキシグルコソンの糖尿病ラット臓器における増加と細胞毒性
鈴木 敬一郎; 高 永鎬; 谷口 直之
糖尿病合併症, Oct. 1999 - 3-デオキシグルコソンの細胞内蓄積及び糖尿病ラット臓器における増加
鈴木 敬一郎; 高 永鎬; 江口 裕伸; 庄野 文恵; 谷口 直之
生化学, Aug. 1998 - Mn-superoxide dismutase(Mn-SOD)のミトコンドリア移行の変異体を用いた解析
藤井 順逸; 池田 義隆; 渡辺 俊哉; 川崎 佳巳; 高橋 素子; 鈴木 敬一郎; 谷口 直之
生化学, Aug. 1998 - LECラットの肝癌発症に伴うヘムオキシゲナーゼの発現
松本 明郎; 華山 力成; 鈴木 敬一郎; 藤井 順逸; 谷口 直之
腫瘍マーカー研究会誌, Mar. 1998 - Involvement of glycation and oxidative stress in diabetic macroangiopathy
N Taniguchi; H Kaneto; R Asahi; M Takahashi; WY Che; S Higashiyama; J Fujii; K Suzuki; Y Kayanoki
DIABETES, Jul. 1996 - Induction of aldose reductase gene expression in LEC rats during the development of the hereditary hepatitis and hepatoma
M Takahashi; A Hoshi; J Fujii; E Miyoshi; T Kasahara; K Suzuki; K Aozasa; N Taniguchi
JAPANESE JOURNAL OF CANCER RESEARCH, Apr. 1996 - Mn-superoxide dismutase
N. Taniguchi; K. Suzuki; M. Ishikawa; T. Nakata
Nippon rinsho. Japanese journal of clinical medicine, 1995 - 運動とラット骨格筋および肝臓の抗酸化酵素システム
大石修司; 木崎節子; 山下 均; 瀬川雅彦; 井澤鉄也; 駒林隆夫; 鈴木敬一郎; 谷口直之; 永田直一; 大野秀樹
第４回健康スポーツ医科学フォーラム集：健康スポーツ核医学研究会編, 1994 - EFFECTS OF CYTOKINES (CTKIL-1 AND TNF) AND ENDOTOXIN (ETX) ON LUNG MANGANESE SUPEROXIDE-DISMUTASE (MNSOD) MESSENGER-RNA, PROTEIN, ACTIVITY, AND IMMUNOHISTOCHEMICAL DISTRIBUTION IN RATS EXPOSED TO HYPEROXIA
CW WHITE; Y LEWISMOLOCK; K SUZUKI; N TANIGUCHI; H SHIMIZU; DH NGUYEN; RJ MASON
AMERICAN REVIEW OF RESPIRATORY DISEASE, Apr. 1993 - 老化反応における蛋白質の糖化によるO-2の産生と遺伝子組変え型SODによる抑制
谷口 直之; 鈴木 敬一郎; 大河原 知水
代謝異常治療研究基金研究業績集, Jan. 1993 Change of superoxide dismutase content in SHRSP myocardium
NISHIDA Shozo; KIMOTO Saori; NAKANO Takayuki; TERAMOTO Kazuhiro; FUNASAKA Kunihiko; SUZUKI Keiichirou; TANIGUCHi Naoyuki; TOMURA Takanori
Medical journal of Kinki University, 30 Dec. 1992- 低酸素刺激による心筋細胞内Mn-SODの合成促進とその機構 : Cキナーゼの役割
藤 久和; 葛谷 恒彦; 星田 四朗; 山下 宜繁; 大江 洋史; 北畠 顕; 多田 道彦; 鎌田 武信; 鈴木 敬一郎; 谷口 直之
Japanese circulation journal, 01 Mar. 1992 - STIMULATION OF MN-SUPEROXIDE DISMUTASE EXPRESSION BY TUMOR-NECROSIS-FACTOR-ALPHA - QUANTITATIVE-DETERMINATION OF MN-SOD PROTEIN-LEVELS IN TNF-RESISTANT AND SENSITIVE CELLS BY ELISA
N TANIGUCHI; T KAWAGUCHI; M ISHIKAWA; K SUZUKI; Y MATSUDA; S HOSHI
FASEB JOURNAL, Mar. 1991
Books and other publications
- Superoxide dismutases in exercise and disease. (共著)
Handbook of Oxidants and Antioxidants in Exercise. (Elsevier), 2000 - The cytotoxicity of methylglyoxal and 3-deoxyglucosone is decreased in the aldehyde reductase gene-transfected cells. (共著)
Adv. Exp. Med. Biol., 2000 - Glycation as oxidative stress and redox regulation : Implications for aging, diabetes, and familial amyotrophic lateral sclerosis. , (共著)
Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases, 1997
Lectures, oral presentations, etc.
- HepG2細胞におけるc-Metのリン酸化に対するNOの影響
江口 裕伸; 浜崎 重彰; 崎山 晴彦; 吉原 大作; 藤原 範子; 塚本 蔵; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Oct. 2023, (公社)日本生化学会 - 家族性ALSを引き起こす変異SOD1の凝集体形成に寄与するIle35
矢埜 杏果; 浅井 新喜; 東野 智行; 吉原 大作; 江口 裕伸; 崎山 晴彦; 鈴木 敬一郎; 藤原 範子
日本生化学会大会プログラム・講演要旨集, Oct. 2023, (公社)日本生化学会 - 鉄欠乏はRedox cycling quinoneによるROS産生と細胞傷害性を増大させる
吉原 大作; 藤原 範子; 江口 裕伸; 崎山 晴彦; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Nov. 2022, (公社)日本生化学会 - ALS原因タンパク質であるSOD1の凝集体形成に必要なアミノ酸配列の同定
東野 智行; 浅井 新喜; 矢埜 杏果; 吉原 大作; 江口 裕伸; 崎山 晴彦; 藤原 範子; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Nov. 2022, (公社)日本生化学会 - 転写因子ChREBPの脂肪組織におけるあらたな役割
崎山 晴彦; リ・ラン; 中川 勉; 江口 裕伸; 吉原 大作; 藤原 範子; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2020, (公社)日本生化学会 - SIN-1およびペルオキシ亜硝酸イオンによるインターロイキン18の発現変化と機能解析
江口 裕伸; 崎山 晴彦; 吉原 大作; 藤原 範子; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2020, (公社)日本生化学会 - Cu/Zn-スーパーオキシドディスムターゼの凝集および線維ゲル形成におけるpH依存性
藤原 範子; 我妻 美千留; 麻見 安雄; 吉原 大作; 江口 裕伸; 崎山 晴彦; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2019, (公社)日本生化学会 - 転写因子ChREBP阻害による抗肥満効果のメカニズムの検討
崎山 晴彦; Lan Li; 中川 勉; 江口 裕伸; 吉原 大作; 藤原 範子; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2019, (公社)日本生化学会 - ニトロ化によるIL-18のIFNγ誘導活性変化と糖代謝経路への影響
江口 裕伸; 崎山 晴彦; 吉原 大作; 藤原 範子; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2019, (公社)日本生化学会 - Cu/Zn-スーパーオキシドディスムターゼの凝集および線維ゲル形成におけるpH依存性
藤原 範子; 我妻 美千留; 麻見 安雄; 吉原 大作; 江口 裕伸; 崎山 晴彦; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2019, (公社)日本生化学会 - 転写因子ChREBP阻害による抗肥満効果のメカニズムの検討
崎山 晴彦; Lan Li; 中川 勉; 江口 裕伸; 吉原 大作; 藤原 範子; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2019, (公社)日本生化学会 - ニトロ化によるIL-18のIFNγ誘導活性変化と糖代謝経路への影響
江口 裕伸; 崎山 晴彦; 吉原 大作; 藤原 範子; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2019, (公社)日本生化学会 - 医学部生の生化学実習に対する実技試験導入の試み
崎山 晴彦; 江口 裕伸; 吉原 大作; 大河原 知水; 成瀬 均; 藤原 範子; 鈴木 敬一郎
医学教育, Jul. 2019, (一社)日本医学教育学会 - ChREBP欠損マウスが有する抗肥満作用の検討
崎山 晴彦; 中川 勉; 井上 美奈子; 江口 裕伸; 吉原 大作; 藤原 範子; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2018, (公社)日本生化学会 - 活性酸素により引き起こされるIL-18の機能変化と糖尿病性腎症への関与の検討
江口 裕伸; 崎山 晴彦; 吉原 大作; 藤原 範子; 鈴木 敬一郎
臨床化学, Jul. 2018, (一社)日本臨床化学会 - ALS原因タンパク質であるSOD1の線維ゲル形成とその物性
藤原 範子; 我妻 美千留; 大場 矢登; 吉原 大作; 徳原 栄一; 江口 裕伸; 崎山 晴彦; 井上 正志; 古川 良明; 鈴木 敬一郎
生命科学系学会合同年次大会, Dec. 2017, 生命科学系学会合同年次大会運営事務局 - 酸化ストレスが細胞内の鉄イオン動態に与える影響
吉原 大作; 藤原 範子; 平山 祐; 丹羽 正人; 江口 裕伸; 崎山 晴彦; 永澤 秀子; 鈴木 敬一郎
生命科学系学会合同年次大会, Dec. 2017, 生命科学系学会合同年次大会運営事務局 - ペルオキシ亜硝酸はIL-18をニトロ化し、STAT3のリン酸化を阻害する
江口 裕伸; 崎山 晴彦; 吉原 大作; 藤原 範子; 鈴木 敬一郎
生命科学系学会合同年次大会, Dec. 2017, 生命科学系学会合同年次大会運営事務局 - 転写因子ChREBP欠損マウスにおける抗肥満効果の解明
崎山 晴彦; 井上 美奈子; 中川 勉; 江口 裕伸; 吉原 大作; 藤原 範子; 鈴木 敬一郎
生命科学系学会合同年次大会, Dec. 2017, 生命科学系学会合同年次大会運営事務局 - Solution oxygen-17 NMR application for observing a peroxidized cysteine residue in oxidized human SOD1
Noriko Fujiwara; Daisaku Yoshihara; Haruhiko Sakiyama; Hironobu Eguchi; Keiichiro Suzuki
Hyperfine Interactions, Dec. 2016 - Carbohydrate response element-binding protein(ChREBP)の活性制御に及ぼすO-GlcNAc修飾の影響
中川 勉; 崎山 晴彦; 山本 和宏; 藤原 範子; 鈴木 敬一郎; 平井 みどり
日本生化学会大会プログラム・講演要旨集, Sep. 2016, (公社)日本生化学会 - 酸化ストレスがChREBP活性化に与える影響の検討
崎山 晴彦; 井上 美奈子; 江口 裕伸; 藤原 範子; 吉原 大作; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2016, (公社)日本生化学会 - Carbohydrate response element-binding protein(ChREBP)の活性制御に及ぼす核移行/核外搬出シグナルの影響
中川 勉; 吉村 友希; 崎山 晴彦; 山本 和宏; 藤原 範子; 鈴木 敬一郎; 平井 みどり
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015, (公社)日本生化学会 - ALS原因タンパク質SOD1の線維化と物性変化
藤原 範子; 我妻 美千留; 大場 矢登; 吉原 大作; 古川 良明; 江口 裕伸; 崎山 晴彦; 井上 正志; 鈴木 敬一郎
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015, (公社)日本生化学会 - SOD1欠損マウスにおける行動学的異常
吉原 大作; 藤原 範子; 江口 裕伸; 崎山 晴彦; 鈴木 敬一郎
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015, (公社)日本生化学会 - ペルオキシ亜硝酸イオンによるIL-18のニトロ化と機能変化
江口 裕伸; 崎山 晴彦; 吉原 大作; 藤原 範子; 是金 敦子; 大河原 知水; 鈴木 敬一郎
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015, (公社)日本生化学会 - 酸化・糖化は肝臓においてコラーゲン蓄積を引き起こす
崎山 晴彦; 米岡 由佳; 江口 裕伸; 藤原 範子; 吉原 大作; 鈴木 敬一郎
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015, (公社)日本生化学会 - ChREBP-βの活性化機構の解明
吉村 友希; 中川 勉; 崎山 晴彦; 山本 和宏; 江口 裕伸; 藤原 範子; 平野 剛; 鈴木 敬一郎; 平井 みどり
日本薬学会年会要旨集, Mar. 2015, (公社)日本薬学会 - ALS原因タンパク質のアミロイド様線維形成に伴う物性変化
藤原 範子; 我妻 美千留; 古川 良明; 吉原 大作; 江口 裕伸; 崎山 晴彦; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Oct. 2014, (公社)日本生化学会 - 活性酸素種によるIL-18の不活性化と糖尿病性腎症への関与の検討
江口 裕伸; 崎山 晴彦; 吉原 大作; 藤原 範子; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Oct. 2014, (公社)日本生化学会 - SOD1欠損が脳内モノアミン代謝に与える影響
吉原 大作; 藤原 範子; 崎山 晴彦; 江口 裕伸; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Oct. 2014, (公社)日本生化学会 - SOD1KOマウスに発症する肝障害への糖・脂質代謝の関与の検討
米岡 由佳; 崎山 晴彦; 藤原 範子; 江口 裕伸; 吉原 大作; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Oct. 2014, (公社)日本生化学会 - 酸化ストレスと転写因子Carbohydrate Response Element-binding Protein(ChREBP)の活性化について
崎山 晴彦; 米岡 由佳; 江口 裕伸; 藤原 範子; 吉原 大作; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Oct. 2014, (公社)日本生化学会 - 溶液酸素NMRによる酸化修飾タンパク質の新規検出方法
藤原 範子; 花島 慎弥; 山口 芳樹; 鄭 国慶; 鳥越 秀峰; 谷口 直之; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2013, (公社)日本生化学会 - 活性酸素種がIL-18の発現に与える影響
江口 裕伸; 崎山 晴彦; 藤原 範子; 吉原 大作; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2013, (公社)日本生化学会 - SOD1 KOマウスの肝臓における糖および脂質代謝の検討
崎山 晴彦; 江口 裕伸; 吉原 大作; 米岡 由佳; 藤原 範子; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2013, (公社)日本生化学会 - SOD1欠損が脳機能に与える影響
吉原 大作; 藤原 範子; 崎山 晴彦; 江口 裕伸; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2013, (公社)日本生化学会 - Cu/Zn-スーパーオキシドジスムターゼのループVI構造は2種類のタイプに分類される
藤原 範子; 伊原 健太郎; 山口 芳樹; 鳥越 秀峰; 若槻 壮市; 谷口 直之; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Dec. 2012, (公社)日本生化学会 - 活性酸素種によるNO産生増強作用の解析
江口 裕伸; 藤原 範子; 崎山 晴彦; 吉原 大作; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Dec. 2012, (公社)日本生化学会 - 転写因子Carbohydrate Response Element-binding Protein(ChREBP)の新規活性化因子の探索
崎山 晴彦; 藤原 範子; 江口 裕伸; 吉原 大作; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Dec. 2012, (公社)日本生化学会 - ヒトSOD1ダイマーのループVI構造は非対称である
藤原 範子; 伊原 健太郎; 鳥越 秀峰; 山口 芳樹; 若槻 壮市; 谷口 直之; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2011, (公社)日本生化学会 - SOD1ノックアウトマウスの腎臓におけるIRP1のリン酸化とその生理的意義
吉原 大作; 藤原 範子; 崎山 晴彦; 江口 裕伸; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2011, (公社)日本生化学会 - ChREBPのグルコース応答におけるO-GlcNAc修飾の生理的役割
崎山 晴彦; 藤原 範子; 江口 裕伸; 吉原 大作; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2011, (公社)日本生化学会 - 過酸化水素はLPSによるNO産生を増強する
江口 裕伸; 藤原 範子; 崎山 晴彦; 吉原 大作; 鈴木 敬一郎
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2010, (公社)日本生化学会 - SOD1ノックアウトマウスの腎臓における鉄代謝異常とその分子機構
吉原 大作; 藤原 範子; 崎山 晴彦; 江口 裕伸; 鈴木 敬一郎
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2010, (公社)日本生化学会 - 2-メルカプトエタノール修飾型Cu,Zn-SODの構造解析と安定性について
藤原 範子; 伊原 健太郎; 鳥越 秀峰; 小笹 哲夫; 金田 薫; 佐々木 澄美; 山口 芳樹; 若槻 壮市; 谷口 直之; 鈴木 敬一郎
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2010, (公社)日本生化学会 - 転写因子Carbohydrate Response Element-binding Protein(ChREBP)の活性化に及ぼすO-GlcNAc修飾及びMlxの役割
崎山 晴彦; 藤原 範子; 江口 裕伸; 吉原 大作; Uyeda Ko; 鈴木 敬一郎
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2010, (公社)日本生化学会 - アセトアルデヒドはグリコアルブミン生成を抑制する
崎山 晴彦; 藤原 範子; 鈴木 敬一郎; 笠山 宗正; 古賀 正史
糖尿病, Apr. 2010, (一社)日本糖尿病学会 - Mlxの結合が転写因子ChREBPの細胞内局在に及ぼす影響の検討
崎山 晴彦; 深澤 昌史; 藤原 範子; 江口 裕伸; 横江 俊一; 吉原 大作; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2009, (公社)日本生化学会 - 抗酸化能を獲得した2-メルカプトエタノール修飾型Cu,Zn-SODの構造解析
藤原 範子; 伊原 健太郎; 若槻 壮市; 谷口 直之; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2009, (公社)日本生化学会 - SOD1ノックアウトマウスの腎臓における鉄の沈着とGSTA4の誘導
吉原 大作; 藤原 範子; 大河原 知水; 崎山 晴彦; 横江 俊一; 江口 裕伸; 鈴木 敬一郎
日本生化学会大会プログラム・講演要旨集, Sep. 2009, (公社)日本生化学会 - 細胞外型スーパーオキシドジスムターゼ(EC-SOD)は血管平滑筋細胞のヘパリン結合型上皮増殖因子様増殖因子(HB-EGF)の発現を抑制する
大河原 知水; 西村 雅史; 藤原 範子; 江口 裕伸; 吉原 大作; 鈴木 敬一郎
生化学, Jul. 2006, (公社)日本生化学会 - ウィルソン病モデルラットでは運動機能の増大とプレパルス抑制の低下が認められる(Increased motor function and reduced prepulse inhibition in Wilson disease model rats)
藤原 範子; 磯 博行; 北中 順惠; 北中 純一; 尾澤 敬一郎; 下田 重朗; 江口 裕伸; 大河原 知水; 竹村 基彦; 鈴木 敬一郎
神経化学, Aug. 2004, 日本神経化学会 - 銅イオンのヒストンH4のアセチル化に対する影響
宮本 泰豪; 康 九紅; 藤原 範子; 三善 英知; 本家 孝一; 鈴木 敬一郎; 谷口 直之
生化学, Aug. 2002, (公社)日本生化学会 - 活性酸素の新しい生理的意義 細胞内小器官の機能制御 細胞外型スーパーオキシドジスムターゼの核移行とその意義
大河原 知水; 山口 幸洋; 高山 英次; 木崎 節子; 池田 義孝; 鈴木 敬一郎; 谷口 直之; 大野 秀樹
生化学, Aug. 2001, (公社)日本生化学会 - 細胞外型スーパーオキシドジスムターゼの核移行性
大河原 知水; 山口 幸洋; 高山 英次; 木崎 節子; 池田 義孝; 大野 秀樹; 谷口 直之; 鈴木 敬一郎
生化学, Apr. 2001, (公社)日本生化学会 - 肝癌組織におけるα1-6 Fucosyltransferaseとフコシル化糖蛋白の発現についての検討
野田 勝久; 三善 英知; 江國 敦子; 池田 義孝; 鈴木 敬一郎; 佐々木 裕; 堀 正二; 松浦 成昭; 林 紀夫; 谷口 直之
日本癌学会総会記事, Aug. 1999, (一社)日本癌学会 - 細胞外型スーパーオキシドジスムターゼのヘパリン結合ドメインは核移行シグナルとして機能する
大河原 知水; 木崎 節子; 大石 修司; 高山 英次; 今関 信夫; 松原 修; 芳賀 脩光; 池田 義孝; 鈴木 敬一郎; 藤井 順逸; 谷口 直之; 大野 秀樹
生化学, Aug. 1999, (公社)日本生化学会 - INHIBITORY EFFECTS OF HYPOXIC PRECONDITIONING ON MYOCARDIAL-CELL INJURY AT LATE-PHASE ARE CLOSELY LINKED TO AN INCREASE IN MN-SOD ACTIVITY OF RAT NEONATAL CARDIAC MYOCYTES
N YAMASHITA; T KUZUYA; S HOSHIDA; M NISHIDA; H OE; K SUZUKI; N TANIGUCHI; M HORI; T KAMADA; M TADA
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, ELSEVIER SCIENCE PUBL B V - CHANGES IN IMMUNOREACTIVE MANGANESE-SUPEROXIDE DISMUTASE LEVEL IN RAT-TISSUES UNDER HYPOBARIC-HYPOXIC ENVIRONMENT
K NAKANISHI; F TAJIMA; A NAKAMURA; T OOKAWARA; H YAMASHITA; K SUZUKI; N TANIGUCHI; H OHNO
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, ELSEVIER SCIENCE PUBL B V - LOCALIZATION, MECHANISM OF INDUCTION AND RELEASE INTO SERUM OF MANGANESE SUPEROXIDE-DISMUTASE IN HUMAN UMBILICAL ENDOTHELIAL-CELLS
K SUZUKI; H TATSUMI; S SATOH; T SENDA; T NAKATA; J FUJII; N TANIGUCHI
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, ELSEVIER SCIENCE PUBL B V - CHARACTERIZATION OF HUMAN MN-SOD AND CU,ZN-SOD EXPRESSED IN BACULOVIRUS-INSECT CELL SYSTEM
J FUJII; Y IKEDA; K SUZUKI; N TANIGUCHI
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, ELSEVIER SCIENCE PUBL B V - FRAGMENTATION OF CU,ZN-SOD AND DNA CLEAVAGE INDUCED BY GLYCATION REACTION
H KANETO; T OOKAWARA; J FUJII; K SUZUKI; N TANIGUCHI
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, ELSEVIER SCIENCE PUBL B V - TRANSFORMING GROWTH-FACTOR-BETA SUPPRESSES EXPRESSION OF ANTIOXIDATIVE ENZYMES IN RAT HEPATOCYTES
Y KAYANOKI; J FUJII; K SUZUKI; Y AIDA; T UCHIKOSHI; S KAWATA; Y MATSUZAWA; N TANIGUCHI
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, ELSEVIER SCIENCE PUBL B V - REGULATION OF HUMAN MN-SOD GENE-EXPRESSION BY CYTOKINES AND OTHER FACTORS
J FUJII; Y KAYANOKI; K SUZUKI; N TANIGUCHI
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, ELSEVIER SCIENCE PUBL B V - EFFECTS OF COLD OR HEAT ENVIRONMENT ON IMMUNOREACTIVE MANGANESE-SUPEROXIDE DISMUTASE IN RAT-TISSUES
T OOKAWARA; T KIZAKI; H YAMASHITA; S OHISHI; Y OHIRA; K SUZUKI; N TANIGUCHI; Y SATO; H OHNO
FRONTIERS OF REACTIVE OXYGEN SPECIES IN BIOLOGY AND MEDICINE, 1994, ELSEVIER SCIENCE PUBL B V - Physical training and Mn-SOD in rat skeletal muscle.
Nagasawa J; Oh-ishi S; Kizaki T; Yamashita H; Radak Z; Asano K; Izawa T; Komabayashi T; Sato Y; Suzuki K; Taniguchi N; Ohno H
Asian Sports Sciences Congress, Proceedings., 1994 - EFFECTS OF CYTOKINES (CTKIL-1 AND TNF) AND ENDOTOXIN (ETX) ON LUNG MANGANESE SUPEROXIDE-DISMUTASE (MNSOD) MESSENGER-RNA, PROTEIN, ACTIVITY, AND IMMUNOHISTOCHEMICAL DISTRIBUTION IN RATS EXPOSED TO HYPEROXIA
CW WHITE; Y LEWISMOLOCK; K SUZUKI; N TANIGUCHI; H SHIMIZU; DH NGUYEN; RJ MASON
AMERICAN REVIEW OF RESPIRATORY DISEASE, Apr. 1993, AMER LUNG ASSOC - INDUCTION OF MN-SOD AND CU, ZN-SOD AFTER TRANSIENT FOREBRAIN ISCHEMIA AND ISCHEMIC TOLERANCE
T OHTSUKI; M MATSUMOTO; K SUZUKI; K KIMURA; N TANIGUCHI; T KAMADA
OXYGEN RADICALS, 1992, ELSEVIER SCIENCE PUBL B V - INDUCED TOLERANCE TO FOLLOWING ISCHEMIC NEURONAL DAMAGES BY PRECEDING OXYGEN RADICAL STRESS
T OHTSUKI; M MATSUMOTO; K KUWABARA; K SUZUKI; K KIMURA; N TANIGUCHI; T KAMADA
OXYGEN RADICALS, 1992, ELSEVIER SCIENCE PUBL B V - STIMULATION OF MN-SUPEROXIDE DISMUTASE EXPRESSION BY TUMOR-NECROSIS-FACTOR-ALPHA - QUANTITATIVE-DETERMINATION OF MN-SOD PROTEIN-LEVELS IN TNF-RESISTANT AND SENSITIVE CELLS BY ELISA
N TANIGUCHI; T KAWAGUCHI; M ISHIKAWA; K SUZUKI; Y MATSUDA; S HOSHI
FASEB JOURNAL, Mar. 1991, FEDERATION AMER SOC EXP BIOL
Affiliated academic society
Research Themes
- メイラード反応の阻害による動脈硬化阻止
- 血管系細胞の酸化ストレスからの保護
- 糖鎖生物学
- メイラード反応と糖尿病
- 血管内皮細胞の研究
- スーパーオキサイドディスムターゼとフリーラジカル
- Prevention of Atherosclerosis by Inhibition of Maillard Reaction
- Protection of blood vessel cells from oxidative stress
- Glycobiology
- Maillard reaction and Diabetes
- Function of endothelial cells
- Superoxide dismutase and free radicals
