Last Updated :2024/09/11
Researcher Information
Research Keyword
Field Of Study
Career
- Sep. 2014 - Present
Hyogo College of Medicine, Department of Chemistry, Professor - Apr. 2007 - Aug. 2014
Wakayama Medical University, Faculty of Medicine, 准教授 - Apr. 2003 - Mar. 2007
Wakayama Medical University, 助教授 - Apr. 1997 - Mar. 2003
Wakayama Medical University, 講師 - Jun. 1995 - Mar. 1997
Osaka University, Graduate School of Engineering - 1995 - 1997
Osaka University, Graduate School of Engineering, Assistant
Research activity information
Paper
- Synthesis of 4-Imidazolidinones from Diamides and Ethynyl Benziodoxolones via Double Michael-Type Addition: Ethynyl Benziodoxolones as Electrophilic Ynol Synthons
Ayaka Shimizu; Atsushi Shibata; Takashi Kano; Yuuichi Kumai; Ryouhei Kawakami; Hiroyoshi Esaki; Kazuaki Fukushima; Norihiro Tada; Akichika Itoh
Organic Letters, Nov. 2022, [Reviewed] - Theoretical Study of the Mechanism of Ribosomal Peptide Bond Formation Using the ONIOM Method.
Kazuaki Fukushima; Hiroyoshi Esaki
Chemical and Pharmaceutical Bulletin, Aug. 2021, [Reviewed]
Lead - Enantioselective Protonation of Cyclic Carbonyl Ylides by Chiral Lewis Acid Assisted Alcohols
Yasunori Toda; Takayuki Yoshida; Kaoru Arisue; Kazuaki Fukushima; Hiroyoshi Esaki; Ayaka Kikuchi; Hiroyuki Suga
Chemistry – A European Journal, Jul. 2021, [Reviewed] - Methoxy Groups Increase Reactivity of Bifunctional Tetraarylphosphonium Salt Catalysts for Carbon Dioxide Fixation: A Mechanistic Study
Yasunori Toda; Yutaka Komiyama; Hiroyoshi Esaki; Kazuaki Fukushima; Hiroyuki Suga
The Journal of Organic Chemistry, Dec. 2019, [Reviewed] - Enantioselective Cycloadditions between Aliphatic Nitrile Oxides and 2-Hydroxystyrenes Catalyzed by Chiral Amine-Urea,
Yasunori Toda; Masato Koyama; Hiroyoshi Esaki; Kazuaki Fukushima; Hiroyuki Suga
Heterocycles, 2018, [Reviewed] - Amine-Urea-Mediated Asymmetric Cycloadditions between Nitrile Oxides and o-Hydroxystyrenes by Dual Activation
Hiroyuki Suga; Yohei Hashimoto; Yasunori Toda; Kazuaki Fukushima; Hiroyoshi Esaki; Ayaka Kikuchi
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Sep. 2017, [Reviewed] - ONIOM Study of a Proton Shuttle-Catalyzed Stepwise Mechanism for Peptide Bond Formation in the Ribosome
Kazuaki Fukushima; Hideo Iwahashi; Morimitsu Nishikimi
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, Oct. 2012, [Reviewed] - Effect of some naturally occurring iron ion chelators on the formation of radicals in the reaction mixtures of rat liver microsomes with ADP, Fe3+ and NADPH
Katsuyuki Minakata; Kazuaki Fukushima; Masayuki Nakamura; Hideo Iwahashi
Journal of Clinical Biochemistry and Nutrition, 2011, [Reviewed] - Substituent Effects on Two Orthogonal p-Systems in Pseudopericyclcic Ring-opening Reaction s of 5-Alkoxy-2-aminooxazoles
Kazuaki Fukushima; Hideo Iwahashi
Chem. Lett., 2006, [Reviewed] - Efficient catalytic effects of Lewis acids in the 1,3-dipolar cycloaddition reactions of carbonyl ylides with imines
H Suga; Y Ebiura; K Fukushima; A Kakehi; T Baba
JOURNAL OF ORGANIC CHEMISTRY, Dec. 2005, [Reviewed] - Natural bond orbital analysis of pericyclic and pseudopericyclic 1,5-electrocyclizations of conjugated azides
K Fukushima; H Iwahashi
HETEROCYCLES, Nov. 2005, [Reviewed] - Effects of Some Naturally Occurring Iron Ion Chelators on In Vitro Superoxide Radical Formation
Tomihiro Hirai; Kazuaki Fukushima; Kazumasa Kumamoto; Hideo Iwahashi
Biological Trace Element Research, 2005, [Reviewed] - Natural bond orbital analysis of pericyclic and pseudopericyclic 1,5-electrocyclizations of conjugated nitrileimines
K Fukushima; H Iwahashi
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, Sep. 2004, [Reviewed] - 1 : 1 Complex of guanine quartet with alkali metal cations detected by electrospray ionization mass spectrometry
K Fukushima; H Iwahashi
CHEMICAL COMMUNICATIONS, 2000, [Reviewed] - 2-Bromo-2,3-diphenylmethano-2,3-dihydronaphthoquinone
T. Oshima; K. Fukushima; T. Kawamoto
Acta Crystallographica Section C Crystal Structure Communications, Apr. 1999, [Reviewed] - Quinolinic acid, α-picolinic acid, fusaric acid, and 2,6-pyridinedicarboxylic acid enhance the Fenton reaction in phosphate buffer
Hideo Iwahashi; Hiroyuki Kawamori; Kazuaki Fukushima
Chemico-Biological Interactions, Apr. 1999, [Reviewed] - Selective cation binding of crown ether acetals in electrospray ionization mass spectrometry
Takumi Oshima; Fumikazu Matsuda; Kazuaki Fukushima; Hatsue Tamura; Gen-etsu Matsubayashi; Ryuichi Arakawa
Journal of the Chemical Society, Perkin Transactions 2, 1998, [Reviewed] - Formation of 5-alkoxy-2-aminooxazoles and their novel reactivity: Equilibrium with nitrile ylide
K Fukushima; YQ Lu; T Ibata
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, Nov. 1996, [Reviewed] - Conversion of donor-substituted homonaphthoquinones to indenonaphthoquinones via intramolecular photoinduced electron-transfer
Hiroshi Moriwaki; Kazuaki Fukushima; Toshikazu Nagai; Takumi Oshima
Chemical Communications, 1996, [Reviewed] - REGIO-SELECTIVITY AND RELATIVE REACTIVITY OF YLIDE FORMATION IN THE REACTION OF KETOCARBENOID WITH HETERO-CUMULENES
Toshikazu Ibata; Motomu Himori; Kazuaki Fukushima; Hiroyuki Suga; Hirofumi Nakano
Heterocyclic Communications, Jan. 1996, [Reviewed] - Formation of acyl-substituted nitrile ylides by Rh-2(OAc)(4)-catalyzed decomposition of alpha-diazocarbonyl compounds in nitriles
K Fukushima; T Ibata
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, Dec. 1995, [Reviewed] - Formation of 2-Alkylaminooxazoles by the Rh2(OAc)4-Catalyzed Reaction of a-Diazocarbonyl Compounds in the Presence of Cyanamides
Toshikazu Ibata; Kazuaki Fukushima
HETEROCYCLES, 1995, [Reviewed] - Thermolysis and photolysis of arylchlorodiazirines in allyl bromide
R. Bonneau; M. Grobys; M. T. H. Liu; M. Himori; K. Fukushima; T. Ibata
Research on Chemical Intermediates, Jan. 1994, [Reviewed] - FORMATION AND REACTION OF ACYL SUBSTITUTED NITRILE YLIDE THROUGH THE RH2(OAC)4-CATALYZED REACTION OF ALPHA-DIAZOCARBONYL COMPOUNDS WITH BENZONITRILE
T IBATA; K FUKUSHIMA
CHEMISTRY LETTERS, Nov. 1992, [Reviewed]
MISC
- Molecular Orbital Calculations on Ground State Nitrilium Betaines
Kazuaki Fukushima
Bulletin of Wakayama Medical University, Liberal Arts and Sciences, 2000 - Density Functional Studies of 1, 5-Cyclization of 3-Carbonyl Nitrile Ylide.
Kazuaki Fukushima
Bulletin of Wakayama Medical University, Liberal Arts and Sciences, 1999 - Ab Initio and Density Functional Studies of Nitrile Ylide and 3-Formyl Nitrile Ylide.
Kazuaki Fukushima
Bulletin of Wakayama Medical College, Premedical School, 1998
Lead
Research Themes
- Quantum Chemical Calculations of Mechanism for Formation of Peptide Bond on the Ribosome
Grant-in-Aid for Scientific Research (C)
01 Apr. 2013 - 31 Mar. 2016 - グアニン4量体の形成
- ニトリルイリドを経由するオキサゾールの生成
- 共役1,3-双極子の1,5-電子環状反応の機構
- Formation of Guanine Quartet
- Formation of Oxazole via Nitrile Ylide
- Mechanism of 1,5-Electrocyclization of Conjgated 1,3-Dipole
- 量子化学計算を用いた酵素反応の反応機構の解明
- 量子化学計算を用いた有機触媒反応の反応機構の解明
