Last Updated :2024/12/13
Researcher Information
Research activity information
Paper
- Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis.
Keigo Nishida; Aiko Hasegawa; Satoru Yamasaki; Ryota Uchida; Wakana Ohashi; Yosuke Kurashima; Jun Kunisawa; Shunsuke Kimura; Toshihiko Iwanaga; Hiroshi Watarai; Koji Hase; Hideki Ogura; Manabu Nakayama; Jun-Ichi Kashiwakura; Yoshimichi Okayama; Masato Kubo; Osamu Ohara; Hiroshi Kiyono; Haruhiko Koseki; Masaaki Murakami; Toshio Hirano
Scientific reports, Jul. 2019, [Reviewed] - Presenilin 1 Regulates NF-κB Activation via Association with Breakpoint Cluster Region and Casein Kinase II.
Tanaka Y; Sabharwal L; Ota M; Nakagawa I; Jiang JJ; Arima Y; Ogura H; Okochi M; Ishii M; Kamimura D; Murakami M
Journal of immunology (Baltimore, Md. : 1950), Oct. 2018, [Reviewed] - Bmi1 Regulates IκBα Degradation via Association with the SCF Complex.
Okuyama Y; Tanaka Y; Jiang JJ; Kamimura D; Nakamura A; Ota M; Ohki T; Higo D; Ogura H; Ishii N; Atsumi T; Murakami M
Journal of immunology (Baltimore, Md. : 1950), Oct. 2018, [Reviewed] - Identification and Analysis of Islet Antigen-Specific CD8+ T Cells with T Cell Libraries.
Ogura H; Preston-Hurlburt P; Perdigoto AL; Amodio M; Krishnaswamy S; Clark P; Yu H; Egli D; Fouts A; Steck AK; Herold KC
Journal of immunology (Baltimore, Md. : 1950), Sep. 2018, [Reviewed] - Rbm10 regulates inflammation development via alternative splicing of Dnmt3b
Toru Atsumi; Hironao Suzuki; Jing-Jing Jiang; Yuko Okuyama; Ikuma Nakagawa; Mitsutoshi Ota; Yuki Tanaka; Takuto Ohki; Kokichi Katsunuma; Koichi Nakajima; Yoshinori Hasegawa; Osamu Ohara; Hideki Ogura; Yasunobu Arima; Daisuke Kamimura; Masaaki Murakami
International Immunology, Dec. 2017, [Reviewed] - Oral treatment with foralumab, a fully human anti-CD3 monoclonal antibody, prevents skin xenograft rejection in humanized mice
Mineko Ogura; Songyan Deng; Paula Preston-Hurlburt; Hideki Ogura; Kunwar Shailubhai; Chantal Kuhn; Howard L. Weiner; Kevan C. Herold
CLINICAL IMMUNOLOGY, Oct. 2017, [Reviewed] - Breakpoint cluster region-mediated inflammation is dependent on casein kinase II (vol 197, pg 3111, 2016)
J. Meng; J. -J. Jiang; T. Atsumi; H. Bando; Y. Okuyama; L. Sabharwal; I. Nakagawa; H. Higuchi; M. Ota; M. Okawara; R. Ishitani; O. Nureki; D. Higo; Y. Arima; H. Ogura; D. Kamimura; M. Murakami
JOURNAL OF IMMUNOLOGY, Jan. 2017, [Reviewed] - Breakpoint Cluster Region-Mediated Inflammation Is Dependent on Casein Kinase II
Jie Meng; Jing-Jing Jiang; Toru Atsumi; Hidenori Bando; Yuko Okuyama; Lavannya Sabharwal; Ikuma Nakagawa; Haruka Higuchi; Mitsutoshi Ota; Momoko Okawara; Ryuichiro Ishitani; Osamu Nureki; Daisuke Higo; Yasunobu Arima; Hideki Ogura; Daisuke Kamimura; Masaaki Murakami
JOURNAL OF IMMUNOLOGY, Oct. 2016, [Reviewed] - Strong TCR-mediated signals suppress integrated stress responses induced by KDELR1 deficiency in naive T cells
Daisuke Kamimura; Yasunobu Arima; Mineko Tsuruoka; Jing-jing Jiang; Hidenori Bando; Jie Meng; Lavannya Sabharwal; Andrea Stofkova; Naoki Nishikawa; Kotaro Higuchi; Hideki Ogura; Toru Atsumi; Masaaki Murakami
INTERNATIONAL IMMUNOLOGY, Mar. 2016, [Reviewed] - Naive T Cell Homeostasis Regulated by Stress Responses and TCR Signaling
Daisuke Kamimura; Toru Atsumi; Andrea Stofkova; Naoki Nishikawa; Takuto Ohki; Hironao Suzuki; Kokichi Katsunuma; Jing-jing Jiang; Hidenori Bando; Jie Meng; Lavannya Sabharwal; Hideki Ogura; Toshio Hirano; Yasunobu Arima; Masaaki Murakami
FRONTIERS IN IMMUNOLOGY, Dec. 2015, [Reviewed] - Impact of recent innovations in the use of mass cytometry in support of drug development
Ala F. Nassar; Hideki Ogura; Adam V. Wisnewski
DRUG DISCOVERY TODAY, Oct. 2015, [Reviewed] - KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR
Daisuke Kamimura; Kokichi Katsunuma; Yasunobu Arima; Toru Atsumi; Jing-jing Jiang; Hidenori Bando; Jie Meng; Lavannya Sabharwal; Andrea Stofkova; Naoki Nishikawa; Hironao Suzuki; Hideki Ogura; Naoko Ueda; Mineko Tsuruoka; Masaya Harada; Junya Kobayashi; Takanori Hasegawa; Hisahiro Yoshida; Haruhiko Koseki; Ikuo Miura; Shigeharu Wakana; Keigo Nishida; Hidemitsu Kitamura; Toshiyuki Fukada; Toshio Hirano; Masaaki Murakami
NATURE COMMUNICATIONS, Jun. 2015, [Reviewed] - Temporal Expression of Growth Factors Triggered by Epiregulin Regulates Inflammation Development
Masaya Harada; Daisuke Kamimura; Yasunobu Arima; Hitoshi Kohsaka; Yuji Nakatsuji; Makoto Nishida; Toru Atsumi; Jie Meng; Hidenori Bando; Rajeev Singh; Lavannya Sabharwal; Jing-Jing Jiang; Noriko Kumai; Nobuyuki Miyasaka; Saburo Sakoda; Keiko Yamauchi-Takihara; Hideki Ogura; Toshio Hirano; Masaaki Murakami
JOURNAL OF IMMUNOLOGY, Feb. 2015, [Reviewed] - Role of cytokine-mediated crosstalk between T cells and nonimmune cells in the pathophysiology of multiple sclerosis
Daisuke Kamimura; Yasunobu Arima; Toru Atsumi; Jie Meng; Lavannya Sabharwal; Hidenori Bando; Hideki Ogura; Jing-Jing Jiang; Eric S. Huseby; Masaaki Murakami
Multiple Sclerosis: A Mechanistic View, Jan. 2015, [Reviewed] - The Gateway Reflex, which is mediated by the inflammation amplifier, directs pathogenic immune cells into the CNS
Lavannya Sabharwal; Daisuke Kamimura; Jie Meng; Hidenori Bando; Hideki Ogura; Chiemi Nakayama; Jing-Jing Jiang; Noriko Kumai; Hironao Suzuki; Toru Atsumi; Yasunobu Arima; Masaaki Murakami
JOURNAL OF BIOCHEMISTRY, Dec. 2014, [Reviewed] - Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development
Tomohiro Miyai; Shintaro Hojyo; Tomokatsu Ikawa; Masami Kawamura; Tarou Irie; Hideki Ogura; Atsushi Hijikata; Bum-Ho Bin; Takuwa Yasuda; Hiroshi Kitamura; Manabu Nakayama; Osamu Ohara; Hisahiro Yoshida; Haruhiko Koseki; Kenji Mishima; Toshiyuki Fukada
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Aug. 2014, [Reviewed] - The Reverse-Direction Method Links Mass Experimental Data to Human Diseases
Hideki Ogura; Toru Atsumi; Hidenori Bando; Lavannya Sabharwal; Moe Yamada; Jing-Jing Jiang; Akihiro Nakamura; Yasunobu Arima; Daisuke Kamimura; Masaaki Murakami
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, Feb. 2014, [Reviewed] - Inflammation Amplifier, a New Paradigm in Cancer Biology
Toru Atsumi; Rajeev Singh; Lavannya Sabharwal; Hidenori Bando; Jie Meng; Yasunobu Arima; Moe Yamada; Masaya Harada; Jing-Jing Jiang; Daisuke Kamimura; Hideki Ogura; Toshio Hirano; Masaaki Murakami
CANCER RESEARCH, Jan. 2014, [Reviewed] - IL-6 and inflammatory diseases
Daisuke Kamimura; Yasunobu Arima; Toshio Hirano; Hideki Ogura; Masaaki Murakami
Cytokine Frontiers: Regulation of Immune Responses in Health and Disease, Jan. 2014, [Reviewed] - Erratum to Disease-Association Analysis of an Inflammation-Related Feedback Loop [Cell Reports 3, (2013) 946-959]
Masaaki Murakami; Masaya Harada; Daisuke Kamimura; Hideki Ogura; Yuko Okuyama; Noriko Kumai; Azusa Okuyama; Rajeev Singh; Jing-Jing Jiang; Toru Atsumi; Sayaka Shiraya; Yuji Nakatsuji; Makoto Kinoshita; Hitoshi Kohsaka; Makoto Nishida; Saburo Sakoda; Nobuyuki Miyasaka; Keiko Yamauchi-Takihara; Toshio Hirano
Cell Reports, May 2013, [Reviewed] - Disease-association analysis of an inflammation-related feedback loop.
Masaaki Murakami; Masaya Harada; Daisuke Kamimura; Hideki Ogura; Yuko Okuyama; Noriko Kumai; Azusa Okuyama; Rajeev Singh; Jing-Jing Jiang; Toru Atsumi; Sayaka Shiraya; Yuji Nakatsuji; Makoto Kinoshita; Hitoshi Kohsaka; Makoto Nishida; Saburo Sakoda; Nobuyuki Miyasaka; Keiko Yamauchi-Takihara; Toshio Hirano
Cell reports, Mar. 2013, [Reviewed] - Regulation of immune cell infiltration into the CNS by regional neural inputs explained by the gate theory
Yasunobu Arima; Daisuke Kamimura; Lavannya Sabharwal; Moe Yamada; Hidenori Bando; Hideki Ogura; Toru Atsumi; Masaaki Murakami
Mediators of Inflammation, 2013, [Reviewed] - The gateway theory: Bridging neural and immune interactions in the CNS
Daisuke Kamimura; Moe Yamada; Masaya Harada; Lavannya Sabharwal; Jie Meng; Hidenori Bando; Hideki Ogura; Toru Atsumi; Yasunobu Arima; Masaaki Murakami
Frontiers in Neuroscience, 2013, [Reviewed] - The gateway theory: How regional neural activation creates a gateway for immune cells via an inflammation amplifier
Hideki Ogura; Yasunobu Arima; Daisuke Kamimura; Masaaki Murakami
Biomedical Journal, 2013, [Reviewed] - Local microbleeding facilitates IL-6- and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells
Masaaki Murakami; Yuko Okuyama; Hideki Ogura; Shogo Asano; Yasunobu Arima; Mineko Tsuruoka; Masaya Harada; Minoru Kanamoto; Yukihisa Sawa; Yoichiro Iwakura; Kiyoshi Takatsu; Daisuke Kamimura; Toshio Hirano
JOURNAL OF EXPERIMENTAL MEDICINE, Jan. 2011, [Reviewed] - IL-6 positively regulates Foxp3(+)CD8(+) T cells in vivo
Takayuki Nakagawa; Mineko Tsuruoka; Hideki Ogura; Yuko Okuyama; Yasunobu Arima; Toshio Hirano; Masaaki Murakami
INTERNATIONAL IMMUNOLOGY, Feb. 2010, [Reviewed] - Preparation of conophylline affinity nano-beads and identification of a target protein
Eriko Suzuki; Hideki Ogura; Kuniki Kato; Izumi Takei; Yasuaki Kabe; Hiroshi Handa; Kazuo Umezawa
BIOORGANIC & MEDICINAL CHEMISTRY, Sep. 2009, [Reviewed] - Hepatic Interleukin-7 Expression Regulates T Cell Responses
Yukihisa Sawa; Yasunobu Arima; Hideki Ogura; Chika Kitabayashi; Jing-Jing Jiang; Toru Fukushima; Daisuke Kamimura; Toshio Hirano; Masaaki Murakami
IMMUNITY, Mar. 2009, [Reviewed] - Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction
Hideki Ogura; Masaaki Murakami; Yuko Okuyama; Mineko Tsuruoka; Chika Kitabayashi; Minoru Kanamoto; Mika Nishihara; Yoichiro Iwakura; Toshio Hirano
IMMUNITY, Oct. 2008, [Reviewed] - IL-6-gp130-STAT3 in T cells directs the development of IL-17+T-h with a minimum effect on that of Treg in the steady state
Mika Nishihara; Hideki Ogura; Naoko Ueda; Mineko Tsuruoka; Chika Kitabayashi; Fumio Tsuji; Hiroyuki Aono; Katsuhiko Ishihara; Eric Huseby; Ulrich A. K. Betz; Masaaki Murakami; Toshio Hirano
INTERNATIONAL IMMUNOLOGY, Jun. 2007, [Reviewed] - Correction to Local microbleeding facilitates IL-6- and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells [The Journal of Experimental Medicine, 208, 1, (2011) 103-114]
Murakami M; Okuyama Y; Ogura H; Asano S; Arima Y; Tsuruoka M; Harada M; Kanamoto M; Sawa Y; Iwakura Y; Takatsu K; Kamimura D; Hirano T
Journal of Experimental Medicine, [Reviewed]
MISC
- A novel regulator of NF kappa B signaling enhances I kappa B alpha ubiquitination and promotes inflammatory disease development
Y. Okuyama; T. Atsumi; J. -J Jiang; A. Nakamura; H. Ogura; J. Meng; D. Kamimura; N. Shii; T. Hirano; M. Murakami
EUROPEAN JOURNAL OF IMMUNOLOGY, Aug. 2016 - Disease-Association Analysis of an Inflammation-Related Feedback Loop (vol 3, pg 946, 2013)
Masaaki Murakami; Masaya Harada; Daisuke Kamimura; Hideki Ogura; Yuko Okuyama; Noriko Kumai; Azusa Okuyama; Rajeev Singh; Jing-Jing Jiang; Toru Atsumi; Sayaka Shiraya; Yuji Nakatsuji; Makoto Kinoshita; Hitoshi Kohsaka; Makoto Nishida; Saburo Sakoda; Nobuyuki Miyasaka; Keiko Yamauchi-Takihara; Toshio Hirano
CELL REPORTS, May 2013 - Inflammation amplifier (IL-6 amplifier) and its targets and regulators
小椋 英樹; 村上 正晃
臨床免疫・アレルギー科, Mar. 2013 - The gateway theory: bridging neural and immune interactions in the CNS
Daisuke Kamimura; Moe Yamada; Masaya Harada; Lavannya Sabharwal; Jie Meng; Hidenori Bando; Hideki Ogura; Toru Atsumi; Yasunobu Arima; Masaaki Murakami
FRONTIERS IN NEUROSCIENCE, 2013 - Local microbleeding facilitates IL-6- and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells (vol 208, pg 103, 2011)
Masaaki Murakami; Yuko Okuyama; Hideki Ogura; Shogo Asano; Yasunobu Arima; Mineko Tsuruoka; Masaya Harada; Minoru Kanamoto; Yukihisa Sawa; Yoichiro Iwakura; Kiyoshi Takatsu; Daisuke Kamimura; Toshio Hirano
JOURNAL OF EXPERIMENTAL MEDICINE, Nov. 2012 - The development of inflammatory diseases via the IL-6 amplifier in fibroblasts
村上 正晃; 小椋 英樹; 平野 俊夫
Cell technology, Nov. 2009 - The mechanism for rheumatoid arthritis-like disease pathology in IL-6 receptor gp130[F759/F759] mutated mice
小椋 英樹; 村上 正晃
Clinical immunology & allergology, Mar. 2007
Research Themes
- Exploration of diseases caused by MARCH dysregulation
Grant-in-Aid for Challenging Research (Exploratory)
Hyogo Medical University
29 Jun. 2018 - 31 Mar. 2020 - The novel molecular mechanism regulating the Inflammation Amplifier
Grant-in-Aid for Young Scientists (B)
01 Apr. 2012 - 31 Mar. 2015 - Screening of the target genes of IL-6 Amp that promotes autoimmune diseases
Grant-in-Aid for Young Scientists (B)
Osaka University
2010 - 2011