Last Updated :2024/09/11
Researcher Information
Field Of Study
Career
- Apr. 2022
兵庫医科大学医学教育センター、准教授へ配置換 - Apr. 2013
兵庫医科大学医学教育学、准教授に配置換 - Apr. 2012 - Mar. 2013
兵庫医大内科学 准教授 - Jun. 2004 - Apr. 2012
兵庫医科大学内科学、講師 - Nov. 2000 - May 2004
兵庫医科大学内科 助手 - Jul. 1999 - Oct. 2000
医療法人大織会 大織診療所内科医師 - Jul. 1993 - Mar. 2000
兵庫医科大学病院第三内科非常勤医師 - Jul. 1991 - Jun. 1993
兵庫医大第三内科医員 - Apr. 1990 - Jun. 1991
公立学校共済組合近畿中央病院内科医師として勤務 - Apr. 1989 - Mar. 1990
兵庫医大第三内科臨床研修医
Educational Background
Research activity information
Paper
- The in vivo antitumor effects of type I-interferon against hepatocellular carcinoma: the suppression of tumor cell growth and angiogenesis.
Hirayuki Enomoto; Lihua Tao; Ryoji Eguchi; Ayuko Sato; Masao Honda; Shuichi Kaneko; Yoshinori Iwata; Hiroki Nishikawa; Hiroyasu Imanishi; Hiroko Iijima; Tohru Tsujimura; Shuhei Nishiguchi
Scientific reports, Sep. 2017 - New malignant grading system for hepatocellular carcinoma using the Sonazoid contrast agent for ultrasonography.
Hironori Tanaka; Hiroko Iijima; Akiko Higashiura; Kazunori Yoh; Akio Ishii; Tomoyuki Takashima; Yoshiyuki Sakai; Nobuhiro Aizawa; Kazunari Iwata; Naoto Ikeda; Yoshinori Iwata; Hirayuki Enomoto; Masaki Saito; Hiroyasu Imanishi; Seiichi Hirota; Jiro Fujimoto; Shuhei Nishiguchi
Journal of gastroenterology, Apr. 2014 - Development of a new in situ hybridization method for the detection of global bacterial DNA to provide early evidence of a bacterial infection in spontaneous bacterial peritonitis.
Hirayuki Enomoto; Shin-ichi Inoue; Akio Matsuhisa; Nobuhiro Aizawa; Hiroyasu Imanishi; Masaki Saito; Yoshinori Iwata; Hironori Tanaka; Naoto Ikeda; Yoshiyuki Sakai; Tomoyuki Takashima; Soji Shimomura; Hiroko Iijima; Hideji Nakamura; Shuhei Nishiguchi
Journal of hepatology, Jan. 2012 - Crucial role of impaired Kupffer cell phagocytosis on the decreased Sonazoid-enhanced echogenicity in a liver of a nonalchoholic steatohepatitis rat model.
Shohei Yoshikawa; Hiroko Iijima; Masaki Saito; Hironori Tanaka; Hiroyasu Imanishi; Naoki Yoshimoto; Tomohiro Yoshimoto; Shizue Futatsugi-Yumikura; Kenji Nakanishi; Tohru Tsujimura; Takashi Nishigami; Atsushi Kudo; Shigeki Arii; Shuhei Nishiguchi
Hepatology research : the official journal of the Japan Society of Hepatology, Aug. 2010 - Vitamin K2 downregulates the expression of fibroblast growth factor receptor 3 in human hepatocellular carcinoma cells.
Ke Cao; Weidong Liu; Hideji Nakamura; Hirayuki Enomoto; Teruhisa Yamamoto; Masaki Saito; Hiroyasu Imanishi; Soji Shimomura; Peiguo Cao; Shuhei Nishiguchi
Hepatology research : the official journal of the Japan Society of Hepatology, Nov. 2009 - Involvement of hepatoma-derived growth factor in the growth inhibition of hepatocellular carcinoma cells by vitamin K(2).
Teruhisa Yamamoto; Hideji Nakamura; Weidong Liu; Ke Cao; Shohei Yoshikawa; Hirayuki Enomoto; Yoshinori Iwata; Noritoshi Koh; Masaki Saito; Hiroyasu Imanishi; Soji Shimomura; Hiroko Iijima; Toshikazu Hada; Shuhei Nishiguchi
Journal of gastroenterology, 2009 - Vitamin K2 inhibits the proliferation of HepG2 cells by up-regulating the transcription of p21 gene.
Weidong Liu; Hideji Nakamura; Teruhisa Yamamoto; Naoto Ikeda; Masaki Saito; Masao Ohno; Naoki Hara; Hiroyasu Imanishi; Soji Shimomura; Tetsuo Yamamoto; Toshiyuki Sakai; Shuhei Nishiguchi; Toshikazu Hada
Hepatology research : the official journal of the Japan Society of Hepatology, May 2007 - Chemoprevention of spontaneous development of hepatocellular carcinomas in fatty liver Shionogi mice by a cyclooxygenase-2 inhibitor.
Weidong Liu; Hideji Nakamura; Tohru Tsujimura; Jidong Cheng; Teruhisa Yamamoto; Yuna Iwamoto; Hiroyasu Imanishi; Soji Shimomura; Tetsuo Yamamoto; Tsutomu Hirasawa; Shuichiro Inagaki; Shuhei Nishiguchi; Toshikazu Hada
Cancer science, Aug. 2006 - Recombinant HBsAg inhibits LPS-induced COX-2 expression and IL-18 production by interfering with the NFkappaB pathway in a human monocytic cell line, THP-1.
Jidong Cheng; Hiroyasu Imanishi; Hiroko Morisaki; Weidong Liu; Hideji Nakamura; Takayuki Morisaki; Toshikazu Hada
Journal of hepatology, Sep. 2005 - Hemochromatosis with mutation of the ferroportin 1 (IREG1) gene.
Weidong Liu; Souji Shimomura; Hiroyasu Imanishi; Yuna Iwamoto; Naoto Ikeda; Masaki Saito; Masao Ohno; Naoki Hara; Tetsuo Yamamoto; Hideji Nakamura; Toshikazu Hada
Internal medicine (Tokyo, Japan), Apr. 2005 - Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells.
Jidong Cheng; Hideji Nakamura; Hiroyasu Imanishi; Weidong Liu; Takayuki Morisaki; Toshihiro Sugiyama; Toshikazu Hada
Biochemical and biophysical research communications, Sep. 2004 - Involvement of cell cycle regulatory proteins and MAP kinase signaling pathway in growth inhibition and cell cycle arrest by a selective cyclooxygenase 2 inhibitor, etodolac, in human hepatocellular carcinoma cell lines.
Jidong Cheng; Hiroyasu Imanishi; Weidong Liu; Hideji Nakamura; Takayuki Morisaki; Kazuya Higashino; Toshikazu Hada
Cancer science, Aug. 2004 - Evaluation of interleukin-12-induced interferon-y production in vitro by peripheral blood mononuclear cells in patients with chronic liver disease.
Hiroyasu Imanishi; Jidong Cheng; Naoto Ikeda; Masaki Saito; Masao Ohno; Naoki Hara; Souji Shimomura; Tetsuo Yamamoto; Yoshiki Amuro; Hiromi Fujiwara; Toshikazu Hada
Hepato-gastroenterology, 2003 - Novel mutation and multiple mutations found in the human butyrylcholinesterase gene.
Weidong Liu; Jidong Cheng; Arata Iwasaki; Hiroyasu Imanishi; Toshikazu Hada
Clinica chimica acta; international journal of clinical chemistry, Dec. 2002 - Inhibition of the expression of alpha-smooth muscle actin in human hepatic stellate cell line, LI90, by a selective cyclooxygenase 2 inhibitor, NS-398.
Jidong Cheng; Hiroyasu Imanishi; Weidong Liu; Atara Iwasaki; Noboru Ueki; Hideji Nakamura; Toshikazu Hada
Biochemical and biophysical research communications, Oct. 2002 - Induction of apoptosis in hepatocellular carcinoma cell lines by emodin.
Xubin Jing; Noboru Ueki; Jidong Cheng; Hiroyasu Imanishi; Toshikazu Hada
Japanese journal of cancer research : Gann, Aug. 2002 - NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines.
Jidong Cheng; Hiroyasu Imanishi; Yoshiki Amuro; Toshikazu Hada
International journal of cancer, Jun. 2002 - Idiopathic hemochromatosis with the mutation of Ala176Val heterozygous for HFE gene.
H Imanishi; W Liu; J Cheng; N Ikeda; Y Amuro; T Hada
Internal medicine (Tokyo, Japan), Jun. 2001 - Investigation of TTV by in situ hybridization in patients with chronic hepatitis.
J Cheng; T Hada; W Liu; H Imanishi; H Iijima; S Shimomura; Y Amuro; A Kubota; K Higashino
Hepatology research : the official journal of the Japan Society of Hepatology, Jul. 2000 - Familial hypocholinesterasemia found in a family and a new confirmed mutation.
W Liu; T Hada; K Fukui; H Imanishi; N Matsuoka; A Iwasaki; K Higashino
Internal medicine (Tokyo, Japan), Jan. 1997 - A fetal intestinal-type alkaline phosphatase produced in Caco-2 cells.
K Fukui; T Hada; H Imanishi; A Iwasaki; K Hirano; K Higashino
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1996 - Establishment of an enzyme immunoassay using monoclonal antibody (HG1-219) and its application for the diagnosis of hepatocellular carcinoma.
T Hada; Y Kinoshita; Y Ichimori; H Imanishi; K Umeyama; Y Amuro; A Toyosaka; E Okamoto; K Higashino
Japanese journal of cancer research : Gann, Dec. 1992 - A variant serum cholinesterase and a confirmed point mutation at Gly-365 to Arg found in a patient with liver cirrhosis.
T Hada; K Muratani; T Ohue; H Imanishi; Y Moriwaki; M Itoh; Y Amuro; K Higashino
Internal medicine (Tokyo, Japan), Mar. 1992 - A hybrid form of alkaline phosphatase produced in FL-amnion cells.
T Hada; H Imanishi; K Muratani; K Hirano; K Higashino
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1991 - A xanthinuric family--the proposita having immunologically reactive xanthine oxidase but no xanthine oxidase activity.
T Yamamoto; Y Moriwaki; S Takahashi; T Hada; M Suda; H Imanishi; O E Agbedana; M Nanahoshi; K Higashino
Advances in experimental medicine and biology, 1991 - Discrimination of liver cirrhosis from chronic hepatitis by analysis of serum cholinesterase isozymes using affinity electrophoresis with concanavalin A or wheat germ agglutinin.
T Hada; T Ohue; H Imanishi; H Nakaoka; A Hirosaki; S Shimomura; M Fujikura; Y Matsuda; T Yamamoto; Y Amuro
Gastroenterologia Japonica, Dec. 1990 - Expression of a hybrid form of alkaline phosphatase isoenzyme in a newly established cell line (HuG-1) from a gastric cancer patient.
H Imanishi; T Hada; K Muratani; K Hirano; K Higashino
Cancer research, Jun. 1990 - Structures of the asparagine-linked oligosaccharides of an alkaline phosphatase, kasahara isozyme, purified from FL amnion cells.
T Endo; K Higashino; T Hada; H Imanishi; K Muratani; N Kochibe; A Kobata
Cancer research, Feb. 1990 - Purification and some properties of the fast migrating alkaline phosphatase in FL-amnion cells (the Kasahara isoenzyme) and its cDNA cloning.
K Higashino; K Muratani; T Hada; H Imanishi; Y Amuro; Y Yamamoto; J Furuyama; K Hirano; Y M Hong; M Shimokura
Clinica chimica acta; international journal of clinical chemistry, Jan. 1990 - An alkaline phosphatase reacting with both monoclonal antibodies to intestinal and placental isoenzymes.
H Imanishi; T Hada; K Muratani; K Hirano; K Higashino
Clinica chimica acta; international journal of clinical chemistry, Jan. 1990 - Alteration of serum cholinesterase isozyme in patients with liver cirrhosis.
T Hada; T Ohue; H Imanishi; H Nakaoka; A Hirosaki; M Fujikura; Y Amuro; K Higashino
Clinica chimica acta; international journal of clinical chemistry, Nov. 1988 - Novel cholinesterase expression in the HuH-7 cell line.
T Hada; T Yamamoto; H Imanishi; S Takahashi; Y Amuro; K Higashino; J Sato
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1987 - Microheterogeneity of Kasahara isozyme.
T Hada; H Imanishi; T Yamamoto; Y Amuro; K Higashino; K Taketa; J Sato
Clinica chimica acta; international journal of clinical chemistry, Aug. 1986
MISC
- UFT,etodolac,ビタミンK2経口投与後著明に改善した門脈腫瘍塞栓を伴う進行肝細胞癌の1例
今西 宏安; 斎藤 正紀; 程 継東; 劉 衛東; 片瀬 竜司; 山本 晃久; 秦 一美; 池田 直人; 大野 正雄; 原 直樹; 下村 壯治; 山元 哲雄; 中村 秀次; 波田 壽一
肝臓, Feb. 2006 - 原発性胆汁性肝硬変患者血清中のインターロイキン-18濃度の測定
今西宏安; 程 継東; 斎藤正紀; 池田直人; 大野正雄; 原 直樹; 下村壯冶; 瀬戸良文; 岩田信生; 山元哲雄; 安室芳樹; 波田壽一
肝臓, 2002, [Reviewed]
Lead
Books and other publications
- 経静脈治療オーダーマニュアル
今西宏安; 西口修平, Contributor
Mar. 2013 - Annual Review 消化器 2005. 11代謝性肝疾患
波田寿一; 今西宏安, Contributor
中外医学社, Jan. 2005 - 臨床検査ガイド 2001
東野一彌; 今西宏安, Contributor
文光堂, Jan. 2001 - 最新内科学体系、代謝疾患部門第10巻「核酸,蛋白,ポルフィリン代謝異常」
波田寿一; 今西宏安, Contributor
中山書店, Feb. 1996 - 最新内科学体系 担癌個体ー生化学異常
東野一彌; 今西宏安, Contributor
Jul. 1995 - Annual Review 消化器 1993、 14.肝癌
東野一彌; 今西宏安, Contributor, 肝癌
中外医学社, Jan. 1993
Lectures, oral presentations, etc.
- Use of monoclonal antibody, D6, for serological test of hepatocellular carcinoma
Imanishi H; Hada. T; AmuroY; Higashino K
15th International Cancer Congress, Aug. 1990 - Expression of a hybrid form of alkaline phospatase isoenzyme in a gastric cancer patient.
H. Imanishi, T. Hada, K. Muratani et al.
6th International Congress on Isozymes , Toyama JAPAN, May 1989 - Expression of a hybrid form of alkaline phospatase isoenzyme in a gastric cancer patient.
Imanishi H; Hada T; Muratani K; Higashino K
1989 Alkaline phosphatase symposium, Feb. 1989, [Invited]
Affiliated academic society
Research Themes
- Design of flipped classroom and its educational effect in medical college
Grant-in-Aid for Challenging Research (Exploratory)
Hyogo Medical University
30 Jun. 2017 - 31 Mar. 2021 - Practice of TBL using the tablet-type device and moodle as interactive learning tool
Grant-in-Aid for Challenging Exploratory Research
Hyogo Medical University
01 Apr. 2014 - 31 Mar. 2017 - Role of hepatoma-derived growth factor in the tumor angiogenesis and the growth of the hepatocellular carcinoma
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
01 Apr. 2012 - 31 Mar. 2016 - Growth inhibition of hepatocellular carcinoma by the regulation of signal pathway of the hepatoma-derived growth factor
Grant-in-Aid for Scientific Research (C)
Hyogo Medical University
2009 - 2011 - Growth suppression of hepatocellular carcinoma by the regulation of the expression and activation of hepatoma-derived growth factor and its receptor
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
2007 - 2008 - Roles of Hepatoma-derived growth factor(HDGF) on the proliferation and differentiation of hepatic stem cells and liver development
Grant-in-Aid for Scientific Research (C)
Hyogo College of Medicine
2003 - 2004
