Last Updated :2025/01/15
Researcher Information
Career
- Apr. 2022 - Present
Hyogo Medical University, 薬学部, 助教 - Jul. 2020 - Mar. 2023
RIKEN, 客員研究員 - Jan. 2019 - Mar. 2022
Hyogo College of Medicine, 解剖学神経科学部門, 非常勤講師 - Jan. 2019 - Mar. 2022
Hyogo University of Health Sciences, School of Pharmacy, 助教 - Dec. 2017 - Dec. 2018
University of Alabama at Birmingham, 専任講師 - Oct. 2014 - Dec. 2017
University of Alabama at Birmingham, 博士研究員 - Jun. 2014 - Oct. 2014
University of Cincinnati, Anesthesiology, 博士研究員 - Apr. 2014 - Jun. 2014
Hyogo College of Medicine, 解剖学講座, 博士研究員
Research activity information
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Paper
- Sympathetic Nervous System Overactivation Induces Colonic Eosinophil-Associated Microinflammation and Contributes to the Pathogenesis of Irritable Bowel Syndrome
Shaoqi Duan; Hirosato Kanda; Feng Zhu; Masamichi Okubo; Taro Koike; Yoshiya Ohno; Toshiyuki Tanaka; Yukiko Harima; Kazunari Miyamichi; Hirokazu Fukui; Shinichiro Shinzaki; Yilong Cui; Koichi Noguchi; Yi Dai
Jul. 2024 - Modulation of Nicotine-Associated Behaviour in Rats By μ-Opioid Signals from the Medial Prefrontal Cortex to the Nucleus Accumbens Shell
Feng Zhu; Hirosato Kanda; Hiroyuki Neyama; Yuping Wu; Shigeki Kato; Di Hu; Shaoqi Duan; Koichi Noguchi; Yasuyoshi Watanabe; Kazuto Kobayashi; Yi Dai; Yilong Cui
Neuroscience Bulletin, Jun. 2024 - Axonal membrane stretch suppresses neuronal excitability by activating mechanosensitive K2P channels at the node of Ranvier
Hirosato Kanda; Koichi Noguchi; Yi Dai
Molecular Brain, Jan. 2023, [Reviewed]
Lead - エビデンスに基づく漢方診療 機能性ディスペプシアモデルラットの胃知覚過敏及び好酸球関連微小炎症に対する抑肝散の効果
今村 信子; 段 韶キ; 近藤 隆; 神田 浩里; 小暮 洋子; 奥川 卓也; 富田 寿彦; 大島 忠之; 福井 広一; 戴 毅; 三輪 洋人; 新崎 信一郎
日本消化管学会雑誌, Jan. 2023 - 発酵オタネニンジンの抗ストレス効果 ランダム化二重盲検プラセボ対照並行群間比較試験
小暮 洋子; 神田 浩里; 池田 真海; 白川 由佳子; 桃崎 祐実; 乾 さやか; 越田 真由; 中村 悠希; 森上 愛弓; 諸見里 奈央; 伊藤 久富; 宮崎 寿次; 位上 健太郎; 岩岡 恵実子; 青木 俊二; 山本 悟史; 戴 毅
薬理と治療, Nov. 2022 - Yokukansan Suppresses Gastric Hypersensitivity and Eosinophil-associated Microinflammation in Rats With Functional Dyspepsia.
Shaoqi Duan; Nobuko Imamura; Takashi Kondo; Hirosato Kanda; Yoko Kogure; Takuya Okugawa; Masashi Fukushima; Toshihiko Tomita; Tadayuki Oshima; Hirokazu Fukui; Koichi Noguchi; Yi Dai; Hiroto Miwa
Journal of neurogastroenterology and motility, Apr. 2022, [Reviewed] - Reactive Oxygen Species Cause Exercise-Induced Angina in a Myocardial Ischaemia-Reperfusion Injury Model
Xiaohang Wang; Hirosato; Takeshi Tsujino; Yoko Kogure; Feng Zhu; Satoshi Yamamoto; Taichi Sakaguchi; Koichi Noguchi; Yi Dai
International Journal of Molecular Sciences, Mar. 2022
Lead - Effects of cooling temperatures via thermal K2P channels on regeneration of high-frequency action potentials at nodes of Ranvier of rat Aβ-afferent nerves
Hirosato Kanda; Sotatsu Tonomura; Jianguo G. Gu
eneuro, Aug. 2021
Lead - Atractylodin Produces Antinociceptive Effect through a Long-Lasting TRPA1 Channel Activation
Hirosato Kanda; Yanjing Yang; Shaoqi Duan; Yoko Kogure; Shenglan Wang; Emiko Iwaoka; Miku Ishikawa; Saki Takeda; Hidemi Sonoda; Kyoka Mizuta; Shunji Aoki; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
International Journal of Molecular Sciences, Mar. 2021
Lead - 〔Major achievements〕Protocol for pressure-clamped patch-clamp recording at the node of Ranvier of rat myelinated nerves
Hirosato Kanda; Sotatsu Tonomura; Yi Dai; Jianguo G. Gu
STAR Protocols, Mar. 2021, [Reviewed]
Lead - Kv4.3 channel dysfunction contributes to trigeminal neuropathic pain manifested with orofacial cold hypersensitivity in rats.
Hirosato Kanda; Jennifer Ling; Ya-Ting Chang; Ferhat Erol; Viacheslav Viatchenko-Karpinski; Akihiro Yamada; Koichi Noguchi; Jianguo G. Gu
The Journal of neuroscience, Jan. 2021, [Reviewed] - Acid increases PGE2 in the duodenal mucosa in rats
Tadahiro Fujimura; Takashi Kondo; Kimiko Kobayashi; Shaoqi Duan; Hirosato Kanda; Tomoaki Kono; Masashi Fukushima; Toshihiko Tomita; Tadayuki Oshima; Hirokazu Fukui; Yoshihito Fujii; Takashi Konemura; Hiroki Okada; Hiroki Yamanaka; Yi Dai; Koichi Noguchi; Hiroto Miwa
Journal of Clinical Biochemistry and Nutrition, 2021 - ラット母子分離ストレスモデルにおける胃十二指腸の微小炎症は胃の痛覚過敏に関与する(Micro-inflammation in the Gastroduodenal Tract Contributes to Gastric Pain Hypersensitivity in MS Model Rats)
段 韶き; 神田 浩里; 近藤 隆; 三輪 洋人; 野口 光一; 戴 毅
PAIN RESEARCH, Dec. 2020 - 虚血性心疾患に関連する心臓痛へのTRPA1チャネルの関与(Involvement of TRPA1 channel in cardiac pain accompanied with ischemic heart disease)
王 暁航; 神田 浩里; 坂口 太一; 野口 光一; 戴 毅
PAIN RESEARCH, Dec. 2020 - Increased TRPV4 expression in non-myelinating Schwann cells is associated with demyelination after sciatic nerve injury
Xiaona Feng; Yasunori Takayama; Nobuhiko Ohno; Hirosato Kanda; a; Yi Dai; Takaaki Sokabe; Makoto Tominaga
Communications Biology, Dec. 2020, [Reviewed] - The ubiquitin E3 ligase Nedd4‐2 relieves mechanical allodynia through ubiquitination of TRPA1 channel in db/db mice
Shenglan Wang; Simin Qi; Yoko Kogure; Hirosato Kanda; Lin Tian; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
European Journal of Neuroscience, Nov. 2020, [Reviewed] - Eosinophil-associated micro-inflammation in the gastroduodenal tract contributes to gastric hypersensitivity in a rat model of early life adversity
Shaoqi Duan; Takashi Kondo; Hiroto Miwa; Yanjing Yang; Shenglan Wang; Hirosato Kanda; a; Yoko Kogure; Nobuko Imamura; Tadahiro Fujimura; Tomoaki Kono; Masashi Fukushima; Katsuyuki Tozawa; Toshihiko Tomita; Tadayuki Oshima; Hirokazu Fukui; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
American Journal of Physiology-Gastrointestinal and Liver Physiology, Nov. 2020, [Reviewed] - Localization of prostaglandin E2 synthases and E-prostanoid receptors in the spinal cord in a rat model of neuropathic pain.
Hirosato Kanda; Kimiko Kobayashi; Hiroki Yamanaka; Masamichi Okubo; Yi Dai; Koichi Noguchi
Brain research, Oct. 2020, [Reviewed]
Lead - Daikenchuto attenuates visceral pain and suppresses eosinophil infiltration in inflammatory bowel disease in murine models
Yoko Kogure; Hirosato Kanda; Shenglan Wang; Yongbiao Hao; Junxiang Li; Satoshi Yamamoto; Koichi Noguchi; Yi Dai
JGH Open, Aug. 2020, [Reviewed] - 〔Major achievements〕TREK-1 and TRAAK Are Principal K+ Channels at the Nodes of Ranvier for Rapid Action Potential Conduction on Mammalian Myelinated Afferent Nerves.
Kanda H; Ling J; Tonomura S; Noguchi K; Matalon S; Gu JG
Neuron, Dec. 2019, [Reviewed]
Lead - TRPA1-expressing lamina propria mesenchymal cells regulate colonic motility.
Yang Y; Wang S; Kobayashi K; Hao Y; Kanda H; Kondo T; Kogure Y; Yamanaka H; Yamamoto S; Li J; Miwa H; Noguchi K; Dai Y
JCI insight, May 2019, [Reviewed] - Effects of norepinephrine and β2 receptor antagonist ICI 118,551 on whisker hair follicle mechanoreceptors dissatisfy Merkel discs being adrenergic synapses
Mayumi Sonekatsu; Steven Lawrence Gu; Hirosato Kanda; Jianguo G. Gu
Molecular Brain, Apr. 2019, [Reviewed] - Urothelial bladder afferent neurons in the rat are anatomically and neurochemically distinct from non-urothelial afferents
Buffie J. Clodfelder-Miller; Hirosato Kanda; Jianguo G. Gu; Judy R. Creighton; Timothy J. Ness; Jennifer J. DeBerry
Brain Research, Jun. 2018, [Reviewed] - Orofacial neuropathic pain induced by oxaliplatin
Jennifer Ling; Ferhat Erol; Viacheslav Viatchenko-Karpinski; Hirosato Kanda; Jianguo G Gu
Molecular Pain, Aug. 2017 - Orofacial neuropathic pain induced by oxaliplatin: downregulation of KCNQ2 channels in V2 trigeminal ganglion neurons and treatment by the KCNQ2 channel potentiator retigabine
Jennifer Ling; Ferhat Erol; Viacheslav Viatchenko-Karpinski; Hirosato Kanda; Jianguo G. Gu
MOLECULAR PAIN, Aug. 2017, [Reviewed] - Effects of cold temperatures on the excitability of rat trigeminal ganglion neurons that are not for cold sensing
Hirosato Kanda; Jianguo G. Gu
JOURNAL OF NEUROCHEMISTRY, May 2017, [Reviewed] - Serotonergic transmission at Merkel discs: modulation by exogenously applied chemical messengers and involvement of I-h currents
Weipang Chang; Hirosato Kanda; Ryo Ikeda; Jennifer Ling; Jianguo G. Gu
JOURNAL OF NEUROCHEMISTRY, May 2017, [Reviewed] - Membrane Mechanics of Primary Afferent Neurons in the Dorsal Root Ganglia of Rats
Hirosato Kanda; Jianguo G. Gu
BIOPHYSICAL JOURNAL, Apr. 2017, [Reviewed] - Microglial TNFα induces COX2 and PGI2 synthase expression in spinal endothelial cells during neuropathic pain
Hirosato Kanda; Kimiko Kobayashi; Hiroki Yamanaka; Masamichi Okubo; Koichi Noguchi
eNeuro, 2017, [Reviewed] - Electrophysiological properties of lumbosacral primary afferent neurons innervating urothelial and non-urothelial layers of mouse urinary bladder
Hirosato Kanda; Buffie J. Clodfelder-Miller; Jianguo G. Gu; Timothy J. Ness; Jennifer J. DeBerry
BRAIN RESEARCH, Oct. 2016, [Reviewed] - Merkel disc is a serotonergic synapse in the epidermis for transmitting tactile signals in mammals
Weipang Chang; Hirosato Kanda; Ryo Ikeda; Jennifer Ling; Jennifer J. DeBerry; Jianguo G. Gu
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Sep. 2016, [Reviewed] - Macrophage-Colony Stimulating Factor Derived from Injured Primary Afferent Induces Proliferation of Spinal Microglia and Neuropathic Pain in Rats
Masamichi Okubo; Hiroki Yamanaka; Kimiko Kobayashi; Yi Dai; Hirosato Kanda; Hideshi Yagi; Koichi Noguchi
PLOS ONE, Apr. 2016, [Reviewed] - Upregulated glial cell line-derived neurotrophic factor through cyclooxygenase-2 activation in the muscle is required for mechanical hyperalgesia after exercise in rats
Shiori Murase; Etsuji Terazawa; Kenji Hirate; Hiroki Yamanaka; Hirosato Kanda; Koichi Noguchi; Hiroki Ota; Fernando Queme; Toru Taguchi; Kazue Mizumura
Journal of Physiology, Jun. 2013, [Reviewed] - COX-1-dependent prostaglandin D2 in microglia contributes to neuropathic pain via DP2 receptor in spinal neurons
Hirosato Kanda; Kimiko Kobayashi; Hiroki Yamanaka; Koichi Noguchi
GLIA, Jun. 2013, [Reviewed] - Up-regulation of platelet-activating factor synthases and its receptor in spinal cord contribute to development of neuropathic pain following peripheral nerve injury
Masamichi Okubo; Hiroki Yamanaka; Kimiko Kobayashi; Hirosato Kanda; Yi Dai; Koichi Noguchi
MOLECULAR PAIN, Feb. 2012, [Reviewed]
MISC
- 交感神経活動による大腸好酸球浸潤の誘導と内臓知覚過敏への関与(Sympathetic activation-induced colonic eosinophil infiltration contributes to visceral hypersensitivity)
段 韶き; 神田 浩里; 野口 光一; 戴 毅
PAIN RESEARCH, Dec. 2023 - 抑肝散はFDモデルラットの胃痛覚過敏と微小炎症を抑制する(Yokukansan suppresses gastric pain hypersensitivity and micro inflammation in FD model rats)
段 韶き; 今村 信子; 近藤 隆; 神田 浩里; 三輪 洋人; 野口 光一; 戴 毅
PAIN RESEARCH, Dec. 2022 - 過酸化水素によるTRPA1チャネルの活性化はPCI後狭心症の発症に関与する(The activation of TRPA1 by cardiac hydrogen peroxide is involved in angina after PCI of a rodent model)
王 暁航; 神田 浩里; 坂口 太一; 野口 光一; 戴 毅
PAIN RESEARCH, Dec. 2021 - 過酸化水素によるTRPA1チャネルの活性化はPCI後狭心症の発症に関与する(The activation of TRPA1 by cardiac hydrogen peroxide is involved in angina after PCI of a rodent model)
王 暁航; 神田 浩里; 坂口 太一; 野口 光一; 戴 毅
PAIN RESEARCH, Dec. 2021 - Maternal separation stress and gastric hypersensitivity
近藤隆; DUAN Shaoqi; DUAN Shaoqi; 神田浩里; 江田裕嗣; 原謙; 田村彰朗; 小川智広; 河野友彰; 福島政司; 富田寿彦; 大島忠之; 福井広一; 戴毅; 三輪洋人
日本消化管学会雑誌, 2021 - ラット十二指腸での酸刺激に伴うプロスタグランジンE2とその受容体の検討
藤村忠宏; 近藤隆; 段韶き; 段韶き; 神田浩里; 今村信子; 富田寿彦; 大島忠之; 福井広一; 岡田啓希; 戴毅; 三輪洋人
Cytoprotection研究会プログラム/抄録, 2021 - 母子分離ラットの胃知覚過敏と胃十二指腸微小炎症との関連
段韶基; 段韶基; 近藤隆; 神田浩里; 河野友彰; 福島政司; 富田寿彦; 大島忠之; 福井広一; 戴毅; 戴毅; 野口光一; 三輪洋人
日本潰瘍学会プログラム・抄録集, 2021 - Basic Investigation for the development of interaction simulator between Kampo products and prescription drugs.
橋本佳奈; 木下淳; 神田浩里; 神田浩里; DAI Yi; DAI Yi; 天野学; 藤野秀樹
日本薬学会年会要旨集(Web), 2021 - Analgesic effect of fermented ginseng and non-fermented ginseng on mustard oil-induced pain
小川栞里; 藤川弘平; 山本奈緒; 小暮洋子; 神田浩里; 神田浩里; 伊藤久富; 宮崎寿次; 位上健太郎; 山本悟史; YI Dai; YI Dai; YI Dai
日本薬学会年会要旨集(CD-ROM), 2020 - Analgesic effect of fermented ginseng and non-fermented ginseng on capsaicin-induced pain
藤川弘平; 小川栞里; 山本奈緒; 小暮洋子; 神田浩里; 神田浩里; 伊藤久富; 宮崎寿次; 位上健太郎; 山本悟史; YI Dai; YI Dai; YI Dai
日本薬学会年会要旨集(CD-ROM), 2020 - 眼窩下神経CCIモデルによる神経障害性疼痛へのKv4.3チャネルの役割
神田浩里; 神田浩里; 神田浩里; DAI Yi; DAI Yi; DAI Yi; 野口光一; GU Jianguo
Pain Research, 2019 - 末梢神経損傷後の脊髄および後根神経節におけるColony-stimulating factorとそれら受容体mRNAの発現
大久保正道; 山中博樹; 小林希実子; 神田浩里; 戴毅; 野口光一
日本運動器疼痛学会誌, 2013 - 脊髄マイクログリアにおけるPGD2とTXA2合成酵素および受容体発現と神経障害疼痛行動への関与
山中博樹; 神田浩里; 小林希実子; 野口光一
日本解剖学会総会・全国学術集会講演プログラム・抄録集, 2013 - Expression of COX1, COX2, PGD(2) and thromboxane A(2) synthases mRNAs in spinal cord following peripheral nerve injury
Hirosato Kanda; Kimiko Kobayashi; Hiroki Yamanaka; Koichi Noguchi
NEUROSCIENCE RESEARCH, 2011 - Receptors involved in flare reaction induced by acupuncture and moxibustion
神田浩里; 岡田薫; 川喜田健司
全日本鍼灸学会雑誌, 2010
